Bone marrow examination is a vital study carried out to attain a positive diagnosis of hematological disorders in a resource low income country like Nigeria specifically in Ondo state. Bone marrow is a main spot of hematopoiesis. It is also a major tool used in diagnosis of non-hematological disorders. The main aim of this study is to examine the outcome of bone marrow aspiration in Ondo state. A retrospective 8 years study was carried out between 2012 till 2020 at the University of medical sciences (former Kidney care center, Trauma center and State specialist hospital, Akure) Ondo state. Age, sex, location of patients, bleeding disorders, various indications and diagnosis were analysed using SPSS version 23. A total of 115 bone marrow aspirations were done at University of medical sciences, Ondo. Majority of the patients were male (58.3%) while 41.7% were females. Most are aged above 45 (46.1%). The most common indication was Anaemia specifically the moderate anaemia (52.2%). Commonest diagnostic findings in our study was Leukemia (42%) followed by Megaloblastic anaemia and Multiple myeloma (12.1%). Given the increase in the prevalence of Megaloblastic anaemia and Iron deficiency anemia globally, our study showed high prevalence rate of leukemia specifically chronic myeloid leukemia. The predominance of leukemia among diagnostic findings in our study has been related to the proximity to tertiary health facility. Low number of cases of other diagnostic findings can be due to lack of accessibility to an improved health center especially those in the rural areas and low population of people in the state. Early diagnosis should be done for effective management of these hematological disorders. Good family support and improved health care system with well trained personnel will help in management of the disease.