Based on the 18 realizations of three state-of-the-art climate models participated in the Coupled Model Intercomparison Project phase 6 (CMIP6), this paper examines the changes in climatology and trends of winter diurnal temperature range (DTR) over East Asia in response to natural and anthropogenic forcings. In the observation, the climatology of DTR during 1979–2014 displays a horizontal tile from southwest to northeast over East Asia. In addition, the observed DTR also presents an obviously declining trend in recent decades, with the magnitude of roughly −0.10 °C decade−1. The historical all-forcing simulations well reproduce the geographical distributions and magnitude of climatology and trends of winter DTR over East Asia in 1979–2014. Furthermore, the winter DTR exhibits a continuous declining trend from the historical scenario to the future SSP245 scenario over East Asia, with the most significant declining during the first half of twenty-first century (i.e., 2021–2060). Based on the individual forcing experiments, it suggests that the greenhouse gases forcing plays a primary role in driving the climatology and trends of DTR over East Asia, especially for the SSP245 scenario. Further analysis indicates that the increasing precipitation under greenhouse gases forcing largely explain the declining DTR trends over East Asia, especially over the northern East Asia both in historical and SSP245 scenarios.