BACKGROUND: Cardiac rehabilitation (CR) has been demonstrated to increase functional capacity in patients with cardiovascular disease (CVD). However, research has found only 14 to 31% of eligible patients participate in facility-based (FB) CR; participation appears to be even lower within the Veteran Administration (VA) with only 8 to 10% of eligible Veterans participating. Home-based (HB) CR may be a viable alternative to expand CR utilization. In a VA quality improvement project, we compared functional gains achieved in FB-CR versus HB-CR for Veterans with CVD. METHODS: Veterans diagnosed with CVD were assessed pre- and post- CR including medical and functional assessment [6 Minute Walk Distance (6MWD), Gait Speed (GS) and Timed Up and Go (TUG)]. Low risk patients were given the option to participate in the FB- or HB-CR program. Moderate and high risk patients participated only in FB-CR. FB-CR entailed standardized exercise training and education; 1 to 3 hospital-based sessions per week over 12 weeks (range of 24-36 sessions). HB-CR entailed an initial onsite exercise education session and then verbal exercise review/reinforcement and education over the phone, one session per week for 12 weeks. After 12 weeks, patients in both groups were reassessed. RESULTS: As shown in the Table, significant improvements in 6MWD, GS, and TUG were evident for both FB- and HB-CR. Similar magnitude of changes were achieved in both CR groups.Table: No title available.Conclusion: FB- and HB-CR were associated with similar improvements in key functional metrics, suggesting that both programs achieve valuable functional gains in patients that ranged in CVD severity. This extends the promise of HB-CR as a format of CR that not only has the potential to increase participation, especially for the many eligible patients who are curtailed by logistics, but to achieve similar efficacy. Functional recovery after a cardiovascular event is a critical step towards improved quality of life and reduced disability.