We prove that the universal central extension of a direct limit of perfect Hom- Lie algebras $$(\mathcal{L_i,\;\alpha_{\mathcal{L}_i}})$$ is (isomorphic to) the direct limit of universal central extensions of $$(\mathcal{L_i,\;\alpha_{\mathcal{L}_i}})$$ . As an application we provide the universal central extensions of some multi-plicative Hom-Lie algebras. More precisely, we consider a family of multiplicative Hom-Lie algebras {(slk $$(\mathcal{A})$$ , αk)}k∈I and describe the universal central extension of its direct limit.
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