Hollow Silicon Research Articles

Aligned Hollow Silicon Nanorods Containing Ionic Liquid Enhanced Solid Polymer Electrolytes with Superior Cycling and Rate Performance.

The low lithium-ion conductivity of polyethylene oxide (PEO)-based polymer electrolytes limits their application in solid-state lithium batteries and related fields. Here, ionic liquids (ILs) are injected into hollow silicon nanorods (HSNRs) to prepare a composite solid polymer electrolyte (CSPE) with aligned HSNRs containing ILs (F-ILs@HSNRs). Applying a magnetic field promoted uniform dispersion and orientation of F-ILs@HSNRs in CSPE. The addition of F-ILs@HSNRs reduced PEO crystallinity and formed Li+ transport pathways at the F-ILs@HSNRs/PEO interface. Calculations and multi-physics simulations reveal that ILs within F-ILs@HSNRs contribute most to lithium-ion conduction, followed by the F-ILs@HSNRs/PEO interface. When F-ILs@HSNRs are arranged perpendicular to the electrodes, the CSPE exhibits the shortest Li+ migration pathways, resulting in stable and efficient lithium-ion conduction. The conductivity (2.14 × 10-4 S cm-1) and lithium-ion migration number tLi+ (0.307) are the highest, being 125 times and 184% higher, respectively, than those of PEO-LiTFSI, when compared to CSPEs with randomly arranged or parallel-aligned F-ILs@HSNRs. Furthermore, Li|CSPE|Li batteries and LiFePO4|CSPE|Li batteries display stable cycling for over 2000h, with coulombic efficiency approaching 100%. Excellent electrochemical reversibility is also confirmed in the rate performance test.

Ultrasound-Triggered NO Release to Promote Axonal Regeneration for Noise-Induced Hearing Loss Therapy.

Intense noise poses a threat to spiral ganglion neurons (SGNs) in the inner ear, often resulting in limited axonal regeneration during noise injury and leading to noise-induced hearing loss (NIHL). Here, we propose an ultrasound-triggered nitric oxide (NO) release to enhance the sprouting and regeneration of injured axons in SGNs. We developed hollow silicon nanoparticles to load nitrosylated N-acetylcysteine, producing HMSN-SNO, which effectively protects NO from external interferences. Utilizing low-intensity ultrasound stimulation with bone penetration, we achieve the controlled release of NO from HMSN-SNO within the cochlea. In mice with NIHL, a rapid and extensive loss of synaptic connections between hair cells and SGNs is observed within 24 h after exposure to excessive noise. However, this loss could be reversed with the combined treatment, resulting in a hearing functional recovery from 83.57 to 65.00 dB SPL. This positive outcome is attributed to the multifunctional effects of HMSN-SNO, wherein they scavenge reactive oxygen species (ROS) to reverse the pathological microenvironment and simultaneously upregulate the CREB/BDNF/EGR1 signaling pathway, thereby enhancing neuroplasticity and promoting the regeneration of neuronal axons. These findings underscore the potential of nanomedicine for neuroplasticity modulation, which holds promise for advancing both basic research and the further treatment of neurological diseases.

Silicon Microthermocycler for Point-of-Care Analytical Systems: Modeling, Design, and Fabrication.

A four-tether silicon microthermocycler for point-of-care PCR analytical systems is proposed. Substituting the commonly employed platinum with titanium in the fabrication of thin film resistance temperature detectors and heaters enabled the realization of a smaller device without compromising temperature accuracy or increasing heater lead power losses. The device was extensively analyzed through analytical modeling and FEM numerical simulations using a 3-D thermo-mechanical simulation model in COMSOL. Numerical simulations revealed that the four-tether design provides a 460% improvement in mechanical strength and a 57% reduction in the thermal time constant compared with a similar three-tether design, with a trade-off of a 22% increase in heat losses. Detailed structural and thermal analyses of crucial design parameters guided the optimization of the final geometry, leading to the successful fabrication of prototypes. It was shown that the current of 60 mA was sufficient to heat the fabricated solid and hollow silicon structure to 132 °C and 134 °C in 10 s for an applied heater power of 510 mW and 525 mW, respectively.

Enhanced effect of ultrasound and gelatin on physical and antibacterial properties of thymol/hollow mesoporous silicon spheres doped zein film

A new antibacterial film, Thy-HMSS/zein film, was prepared from hollow mesoporous silicon spheres loaded with thymol (Thy-HMSS) by ultrasonic optimization casting method (150 W power ultrasonic treatment solution for 3 min). To further enhance the film quality, a composite film, Thy-HMSS/Zein-gelatin film (Thy-HMSS/ZG film), was created by incorporating gelatin into zein. Compared to film containing the same amount of Thy, the effective protection and slow-release effect of HMSS on Thy resulted in a lower release rate of Thy in Thy-HMSS/zein films in the first 2 h, while the total amount of Thy released increased by 10 %. The appearance and structure of the films were optimized by ultrasonic treatment, which reduced the surface bubbles, cross section pores and particle agglomeration. The addition of gelatin enhanced the antibacterial effect of the film, the inhibition zone diameters of Escherichia coli and Staphylococcus aureus can be increased by up to 123.53 % and 159.37 %, respectively. Both Thy-HMSS/zein film and Thy-HMSS/ZG film showed no toxicity in cytotoxicity tests and exhibited good anti-corrosion ability when applied to blueberry preservation. Therefore, the combination of HMSS encapsulation with ultrasonic treatment and gelatin addition represents a suitable and straightforward approach for producing excellent antimicrobial films with superior appearance, structure, and antibacterial properties. This method holds significant potential in the food industry for producing sustainable active packaging materials while also offering new avenues for employing various techniques in films preparation.

PH and temperature dual-responsive hollow mesoporous silica nanoparticles for drug encapsulation and delivery

In this work, pH and temperature dual-responsive drug delivery vehicles (CDs/PNVCL@HMSNs) with 57.05% drug loading efficiency were prepared. Hollow mesoporous silicon nanoparticles (HMSNs) were synthesized by selective etching. The mixed shells on the surface of HMSNs were composed of carbon dots (CDs) and poly (N-vinylcaprolactam) (PNVCL), which were linked to HMSNs via Schiff base reaction. At room environment (pH = 7.4, T = 25 °C), PNVCL was stretched, so that the model drug Doxorubicin (DOX) could be transported freely through the mesopores. In the blood stream (pH = 7.4, T = 37 °C), PNVCL was collapsed, and DOX was encapsulated to form PNVCL@HMSNs-DOX. CDs were grafted to give CDs/PNVCL@HMSNs-DOX and could further inhibit the leakage of drugs. At the acidic environment of the tumor site, Schiff base bonds broke, leading to shell shedding and DOX release. The drug release could be real-time monitored by the change in fluorescence intensity, which was confirmed by the linear fitting of the fluorescence strength of CDs and the percentage of DOX released. CDs/PNVCL@HMSNs are intriguing drug delivery systems (DDSs), which can combine real-time monitoring and control of drug release.

Synergistic Protecting-Etching Synthesis of Carbon Nanoboxes@Silicon for High-Capacity Lithium-Ion Battery.

Silicon (Si) is considered as the most likely choice for the high-capacity lithium-ion batteries owing to its ultrahigh theoretical capacity (4200 mA h g-1) being over 10 times than that of traditional graphite anode materials (372 mA h g-1). However, its widespread application is limited by problems such as a large volume expansion and low electrical conductivity. Herein, we design a hollow nitrogen-doped carbon-coated silicon (Si@Co-HNC) composite in a water-based system via a synergistic protecting-etching strategy of tannic acid. The prepared Si@Co-HNC composite can effectively mitigate the volume change of silicon and improve the electrical conductivity. Moreover, the abundant voids inside the carbon layer and the porous carbon layer accelerate the transport of electrons and lithium ions, resulting in excellent electrochemical performance. The reversible discharge capacity of 1205 mA h g-1 can be retained after 120 cycles at a current density of 0.5 A g-1. In particular, the discharge capacity can be maintained at 1066 mA h g-1 after 300 cycles at a high current density of 1 A g-1. This study provides a new strategy for the design of Si-based anode materials with excellent electrical conductivity and structural stability.

Acidity-activated degradable Mn-engineered silicon nanohybrids coordinated with iprodione for high-efficiency management of Sclerotinia sclerotiorum and nutrient enhancement to crops

Nanocarriers that respond to environmental stimuli are highly desirable in optimizing the bioavailability of pesticides while minimizing side effects. Manganese-engineered nanomaterials hold promising prospects in agriculture as versatile carriers for both intelligent controlled pesticide delivery and crop nutrient enhancement. Here, Mn-engineered hollow silicon nanospheres (Mn-HSNs) with a bubble-like structure were synthesized for encapsulating iprodione (IPR) to obtain IPR-loaded Mn-HSNs (IPR@Mn-HSNs). Due to its high surface area of 261.28 m2/g and surface-enriched active sites, Mn-HSNs demonstrated a commendable loading capacity of 56.4 % for IPR. Results indicated that the -Si-O-Mn- hybrid framework of IPR@Mn-HSNs not only facilitated acidity-triggered IPR release capability but also served as a plentiful source of Mn ion and orthosilicic acid (Si(OH)4) to promote crop growth. The release amount of IPR in an acidic environment generated by Sclerotinia sclerotiorum of oilseed rape was 3.14 times higher than that under neutral conditions. In vitro experiments demonstrated that the antibacterial activity of IPR@Mn-HSNs was about 1.2 times higher than that of commercial IPR suspension concentrate. Appreciably, IPR@Mn-HSNs could be effectively transported to different parts of rapeseed plants through foliar spray, thereby enhancing the effectiveness of pesticide utilization. More importantly, IPR@Mn-HSNs had no discernible impact on the survival of Harmonia axyridis and were relatively safe for HL-7702 and HK-2 cells. Therefore, this work offers valuable insights into the development of an efficient and environmentally friendly pesticide nanoformulation for sustainable and eco-friendly plant protection in agriculture.

Inhibition of growth of hepatocellular carcinoma by co-delivery of anti-PD-1 antibody and sorafenib using biomimetic nano-platelets

BackgroundTraditional nanodrug delivery systems have some limitations, such as eliciting immune responses and inaccuracy in targeting tumor microenvironments.Materials and methodsTargeted drugs (Sorafenib, Sora) nanometers (hollow mesoporous silicon, HMSN) were designed, and then coated with platelet membranes to form aPD-1-PLTM-HMSNs@Sora to enhance the precision of drug delivery systems to the tumor microenvironment, so that more effective immunotherapy was achieved.ResultsThese biomimetic nanoparticles were validated to have the same abilities as platelet membranes (PLTM), including evading the immune system. The successful coating of HMSNs@Sora with PLTM was corroborated by transmission electron microscopy (TEM), western blot and confocal laser microscopy. The affinity of aPD-1-PLTM-HMSNs@Sora to tumor cells was stronger than that of HMSNs@Sora. After drug-loaded particles were intravenously injected into hepatocellular carcinoma model mice, they were demonstrated to not only directly activate toxic T cells, but also increase the triggering release of Sora. The combination of targeted therapy and immunotherapy was found to be of gratifying antineoplastic function on inhibiting primary tumor growth.ConclusionsThe aPD-1-PLTM-HMSNs@Sora nanocarriers that co-delivery of aPD-1 and Sorafenib integrates unique biomimetic properties and excellent targeting performance, and provides a neoteric idea for drug delivery of personalized therapy for primary hepatocellular carcinoma (HCC).

Porous silicon nanotube bundles as nanocarriers for small interfering RNA delivery

AbstractWe describe in this work an evaluation of bundles of hollow mesoporous silicon nanotubes to facilitate transfection of HeLa cells using small interfering RNA designed to knock down expression of Enhanced Green Fluorescent Protein (eGFP). These experiments entail direct visualization of the nanotube bundles associated with the cells using both scanning electron microscopy (SEM) and confocal fluorescence imaging. These nanotube bundles are generated by surface modification of nanotube arrays with aminopropyl‐triethoxysilane (APTES), followed by their ultrasonication in water, to create the amine‐terminated structures capable of electrostatic conjugation of siRNA at an efficiency of 23%–50% (depending on initial siRNA concentration). Delivery and transfection to HeLa cells are verified by quantification of fluorescence imaging; an average percent knockdown of ∼50% eGFP is achieved. As nanoscale drug delivery vehicles are expected to be resorbed in clinical use, we also assess SiNT bundle degradation during the above in vitro timescale using scanning and transmission electron (TEM) microscopies. We conclude with a brief discussion of challenges and opportunities in future experiments involving this platform.

Laplace Differentiator Based on Metasurface with Toroidal Dipole Resonance

AbstractAs an important method of image processing, image differentiation enables edge detection of targets to achieve recognition of object features and information compression and the computation speed can be boosted by optical information techniques. Traditional optical image differentiation methods mainly rely on spatial spectrum filtering by using classical 4f system, while some work focus on 1D or single‐direction differentiation. It is only in recent years that the rapid development of metasurfaces has facilitated image differentiation methods. In this work, a Laplace operation device is demonstrated based on a silicon hollow brick dielectric resonant metasurface for incident light field. The optical transfer function (OTF) required by the optical Laplace operation can be obtained by exciting an angularly selective toroidal dipole (TD) resonance supported by the metasurface. This hollow silicon brick differentiator not only realizes 2D second‐order edge detection but also has a numerical aperture close to 0.4 and a broad working wavelength range >100 nm and can be directly integrated with imaging systems. Such metadevice may be potentially applied in the fields of optical sensing, microscopy, machine vision, biomedical imaging, etc.

A Biomimetic Nanocarrier Strategy Targets Ferroptosis and Efferocytosis During Myocardial Infarction.

Myocardial infarction (MI) is characterized by irreversible cardiomyocyte death resulting from an inadequate supply of oxygenated blood to the myocardium. Recent studies have indicated that ferroptosis, a form of regulated cell death, exacerbates myocardial injury during MI. Concurrently, the upregulation of CD47 on the surface of damaged myocardium following MI impairs the clearance of dead cells by macrophages, thereby hindering efferocytosis. In this context, simultaneously inhibiting ferroptosis and enhancing efferocytosis may represent a promising strategy to mitigate myocardial damage post-MI. In this study, we engineered platelet membrane-coated hollow mesoporous silicon nanoparticles (HMSN) to serve as a drug delivery system, encapsulating ferroptosis inhibitor, Ferrostatin-1, along with an anti-CD47 antibody. We aimed to assess the potential of these nanoparticles (designated as Fer-aCD47@PHMSN) to specifically target the site of MI and evaluate their efficacy in reducing cardiomyocyte death and inflammation. The platelet membrane coating on the nanoparticles significantly enhanced their ability to successfully target the site of myocardial infarction (MI). Our findings demonstrate that treatment with Fer-aCD47@PHMSN resulted in a 38.5% reduction in cardiomyocyte ferroptosis under hypoxia, indicated by decreased lipid peroxidation and increased in vitro. Additionally, Fer-aCD47@PHMSN improved cardiomyocyte efferocytosis by approximately 15% in vitro. In MI mice treated with Fer-aCD47@PHMSN, we observed a substantial reduction in cardiomyocyte death (nearly 30%), decreased inflammation, and significant improvement in cardiac function. Our results demonstrated that the cooperation between the two agents induced anti-ferroptosis effects and enhanced dead cardiomyocyte clearance by macrophage as well as anti-inflammation effects. Thus, our nanoparticle Fer-aCD47@PHMSN provides a new therapeutic strategy for targeted therapy of MI.

Hollow Mie resonators based on toroidal magnetic dipole mode with enhanced sensitivity in refractometric sensing

We propose a refractometric sensor based on hollow silicon Mie resonators of a toroidal magnetic dipole mode. This mode has a pair of antiparallel electric dipoles perpendicular to the silica substrate; thus, the radiation of the mode is suppressed, resulting in an ultra-narrow reflection peak linewidth of 0.35 nm. In addition, the hollow structure enhances the interaction between the enhanced electric field and the surrounding medium, thus improving the sensitivity. The proposed Mie resonators achieve a sensitivity of 486 nm RIU−1 and a figure of merit up to 1389 RIU−1, which are ideal for refractometric sensing.

Fabrication of antireflective coatings with self-cleaning function using Si–Ti modified hollow silicon mixed sol

The antireflective coating (ARC) is fabricated by the sol-gel method using mixed sol modified by Si–Ti composite sol. The effects of the mixing ratio of Si–Ti composite sol and hollow silica sol on the surface morphology, optical properties, mechanical properties, and wetting ability of the ARC were studied. Moreover, the self-cleaning ability and environmental stability were examined via dip coating the modified sol on glass substrates. The proposed ARC exhibited a total solar-weighted transmittance (Тsw) of more than 94.97% over a wavelength range of 380–1100 nm, significantly higher than that of the bare glass substrate (Тsw = 90.62%). After modification, the proposed ARC exhibited a hardness of 3 H. In addition, the coating presented an extremely hydrophilic surface with a minimum water contact angle of less than 5°. Water droplets resulted in the formation of a water film on the ARC surface, which could significantly reduce the adverse effects of subsequent pollutants on the coating transmittance; simultaneously, owing to the introduction of TiO2, the coating could oxidatively decompose organic contamination. Finally, damp test results showed that the ARC transmittance only decreased by 0.05%, indicating good environmental stability.

Highly dense calcium phosphate ceramics prepared by self-hydration with hollow silicon calcium additives

Vertebral compression fractures are common nowadays. The application of calcium phosphate bone cement (CPCs) in the treatment of vertebral compression fractures is the research focus, because of its advantages of good biocompatibility, bone conductivity and injectability. However, it is still limited in the clinical application because of its poor mechanical properties. The main reason for the insufficient strength of CPC is that there are many defects inside the solidified body during the hydration reaction. Therefore, we design a kind of hollow silicon calcium additives to regulate the crystallization behavior of CPC hydration products in the self-curing process to achieve the densification of solidified bodies in the microstructure. Firstly, we plan to increase the nucleation site of hydration products during α-TCP hydration to fill structural defects by introducing hollow bioglass. Secondly, we prepare hollow calcium silicon additive by in situ mineralization which can dissolve calcium and silicon ions efficiently are used to regulate the local hydration microenvironment to reduce the crystal size and increase the number of hydration products to obtain a highly dense solidified body structure. The experimental results show that the initial hydration intensity of CPC increased from 18.36 ± 1.72 MPa to 35.37 ± 1.84 MPa, an increase of about 92.65 %. Also, the toughness of the solidified body has been greatly improved, reaching more than 200 %. After 7 days of hydration, the mechanical strength of CPC was further improved, reaching 89.39 ± 3.65 MPa. With the addition of hollow calcium silica additives, we achieved the conversion from calcium phosphate cement to the calcium phosphate ceramic. Our work provides reference value for the clinical replacement of calcium phosphate ceramic for PMMA in vertebral compression fractures.

Hollow silicon carbide microspheres for excellent and lightweight electromagnetic wave absorber

Developing semiconductor ceramic materials with lightweight, outstanding stability, and high-performance electromagnetic wave (EMW) absorption are attractive for harsh environments. Due to thermal and chemical stability, designable microstructure, and tunable dielectric property, microstructured silicon carbide (SiC) ceramics offer promising potential as excellent EMW absorbers while limited by the scarce fabricating methods. Here, a simple coaxial electrospinning technology and the high-temperature calcination process are developed for the first time to fabricate hollow SiC microspheres (HSCMs) for EMW absorbers. Owing to the sizeable SiC-free space interface in the shell and internal void, the inner hollow structure also endows HSCMs with excellent EMW absorbing properties. By comparing with the composite of 40 wt% solid SiC microspheres (SSCMs)/paraffine, it is found that the 40 wt% HSCMs/paraffin composite exhibits superior dielectric properties and a minimum reflection loss (RL) value of − 61.6 dB at 7.7 GHz and 3.4 mm thickness, associated with the most considerable adequate absorption bandwidth of 4.9 GHz (from 12.6 to 17.5 GHz) at 1.9 mm thickness. This work gives rise to a handy method for fabricating hollow SiC with lightweight and high-efficiency EMW absorption. It will potentially boost the development of next-generation EMW absorbers for harsh environment applications.

Delocalized Electric Field Enhancement through Near-Infrared Quasi-BIC Modes in a Hollow Cuboid Metasurface.

The two main problems of dielectric metasurfaces for sensing and spectroscopy based on electromagnetic field enhancement are that resonances are mainly localized inside the resonator volume and that experimental Q-factors are very limited. To address these issues, a novel dielectric metasurface supporting delocalized modes based on quasi-bound states in the continuum (quasi-BICs) is proposed and theoretically demonstrated. The metasurface comprises a periodic array of silicon hollow nanocuboids patterned on a glass substrate. The resonances stem from the excitation of symmetry-protected quasi-BIC modes, which are accessed by perturbing the arrangement of the nanocuboid holes. Thanks to the variation of the unit cell with a cluster of four hollow nanocuboids, polarization-insensitive, delocalized modes with ultra-high Q-factor are produced. In addition, the demonstrated electric field enhancements are very high (103-104). This work opens new research avenues in optical sensing and advanced spectroscopy, e.g., surface-enhanced Raman spectroscopy.

Molecular dynamics simulation of hollow and porous amorphous silicon nanowires coated with amorphous aluminum oxide

Silicon causes structural changes and residual stresses during the process of lithium-ion penetration. Aluminum oxide coatings with an optimal thickness can prevent the structural variations and failure of the anode, though it will affect the ionic conductivity. In this research, the mechanical and electrochemical properties of the aluminum oxide-coated silicon nanowires are investigated by the molecular dynamics simulations. The results of the simulations show that the capacity increases, and the dimensional stability is maintained to a suitable extent by applying the void space or creating porosity in the coated nanowires. Furthermore, the volumetric changes for the base sample decrease from 56.3% to 10.25% and 19.1% for porous and hollow Si nanowires samples, respectively. Nevertheless, the capacity is increased from 1015.3 to 1063.8, 1219.6, and 1573.3 mAhg−1 for porous, closed, and open-hole samples, respectively. The radial distribution of the residual stresses and elemental mapping are also measured to investigate the effect of porosity and void space on the amorphous nanowires.

Facile synthesis of hollow SiC/C nanospheres for high-performance electromagnetic wave absorption

Hollow silicon carbide/carbon (SiC/C) nanospheres have found wide applications owing to their excellent dielectric properties, high surface area, thermal insulation, and low effective density at high temperatures. However, their hollow structure is typically obtained by removing the templates using strong acids, which can lead to massive waste and severe pollution. Herein, a three-layer nanospheres containing resorcinol-formaldehyde (RF) and SiO2 (RF@SiO2@RF) were first prepared by a simple one-step method and used as precursors. Subsequently, monodispersed hollow SiC/C nanospheres (90 ± 5 nm in diameter) prepared in-situ through carbon thermal reduction. The hollow structure was formed by pyrolysis, eliminating the extra procedure to remove templates. The structure, size, and composition of the nanospheres were precisely controlled via synthesis temperatures (1400, 1450, 1500 °C) and using different raw material ratios. The obtained hollow SiC/C nanospheres demonstrated remarkable resistance to high temperature resistance. The specific surface area of the optimised hollow SiC/C nanospheres reached 301.9 m2 g−1. Their reflection loss (RL) value achieved −41.34 dB at 14.58 GHz, and the effective absorption bandwidth(EAB)was 4.0 GHz (12.77–16.78 GHz) with a thickness of 1.70 mm. The results of this study confirm that the proposed method allows for an in-situ synthesis of hollow SiC/C nanospheres for high temperature microwave absorption with low matching thickness.

Preparation of Buffered Nano-Submicron Hierarchical Structure Hollow SiOx @C Anodes for Lithium-Ion Battery Materials with Carboxymethyl Chitosan.

Silicon-based materials are among the most promising anode materials for next-generation lithium-ion batteries. However, the volume expansion and poor conductivity of silicon-based materials during the charge and discharge process seriously hinder their practical application in the field of anodes. Here, we choose carboxymethyl chitosan (CMCS) as the carbon source coating and binding on the surface of nano silicon and hollow silicon dioxide (H-SiO2 ) to form a hierarchical buffered structure of nano-hollow SiOx @C. The hollow H-SiO2 can alleviate the volume expansion of nano silicon during the lithiation process under continuous cycling. Meanwhile, the carbon layer carbonized by CMCS containing N-doping further regulates the silicon's expansion and improves the conductivity of the active materials. The as- prepared SiOx @C material exhibits an initial discharge capacity of 985.4 mAh g-1 with the decay rate of 0.27 % per cycle in 150 cycles under the current density of 0.2 A g-1 . It is proved that the hierarchical buffer structure nano-hollow SiOx @C anode material has practical application potential.

Oxidation-Resistant Silicon Nanosystem for Intelligent Controlled Ferrous Foliar Delivery to Crops.

Since ferrous (Fe(II)) is the main form of plant absorption, traditional ferrous foliar fertilizers (TFFF) are widely used in modern agriculture. However, TFFF suffer from the shortcomings of weak antioxidant capacity (AC), low foliar adhesion efficiency (FAE), poor fertilizer utilization efficiency (FUE), and noncontrollable slow-release behavior. To overcome these limitations, an oxidation-resistant silicon nanosystem for intelligent controlled ferrous foliar delivery to crops was first developed by using environmentally friendly micro/nano structured hollow silicon as carrier, and combining with vitamin C (in situ antioxidant) to synthesize an oxidation-resistant ferrous foliar fertilizer (ORFFF) for ameliorating Fe-deficiency in crops and increasing crop yield. Compared with TFFF, the ORFFF has excellent ferrous AC (only 11.5% of Fe(II) was oxidized in ORFFF within 72 h), ultrahigh FAE (∼84% of adhesion percentage (%) after two-times simulated rain rinsing), nutrient slow-release ability (720 h gradually release 100.6 mg·g-1), pH-controlled release ability (pH 3-8), and verified high biological safety (100% survival rate for zebrafish and earthworm). The pot experiments showed that ORFFF can correct the Fe-deficiency symptoms of tomato seedlings promptly compared with TFFF, and the FUE of ORFFF is 4.2 times that of TFFF. The specific pH responsiveness of ORFFF can control the slow-release rate of Fe(II) to satisfy the needs of Fe in varying crops and different growing periods of crops. This work provides a feasible way to achieve green and safe Fe supplementation for crops, reduce Fe fertilizer waste, avoid soil pollution caused by Fe fertilizer abuse, and promote the sustainable development of modern nanoagriculture.