History Of Systemic Disease Research Articles

Clinical profile of 108 cases of oral lichen planus.

Oral lichen planus (OLP) is a T cell-mediated chronic inflammatory disease with a varied clinical presentation. The present clinical study was carried out to clarify the demographic and clinical profile of 108 patients with OLP. The patients were identified based on the diagnostic criteria proposed by van der Meij et al. (2003) modified from the WHO (1978) clinical and histopathologic definition of OLP. Information such as age, gender, clinical presentation and type of OLP, site of involvement, symptoms, extraoral involvement, history of systemic disease, familial occurrence and risk factors like chewing and smoking tobacco, chewing betel quid, alcohol consumption were obtained. Mean age of OLP patients was 45.4 years, and among the identified patients, 70.4% were females. The most frequent clinical type was the reticular form (80.6%). The OLP lesions were symptomatic in 77.8% of the patients. The buccal mucosa was the most affected site (87.9%) and multiple oral lesions were observed in 41.7% of the patients. Among the OLP patients, 36.1% and 4.7% reported chewing tobacco and smoking tobacco, respectively. Histopathologically, epithelial dysplasia was seen in two cases. The chronic nature of OLP warrants patient education, psychological support and long-term follow up. (J Oral Sci 58, 43-47, 2016).

Effects of balance training on post-sprained ankle joint instability.

Effects of balance training on post-sprained ankle joint instability.

Prevalence of dyslalias in 8 to 16 year-old students with anterior open bite in the municipality of Envigado, Colombia.

BackgroundAnterior open bite AOB is the most common malocclusion associated with speech disorders and the literature has shown that problems of occlusion involve all oral functions. AOB not only produce aesthetic and occlusal problems for the patient and modifies the union of the lips, tongue, teeth, palate, palatal rugae and oropharynx, and thus affecting the ability to communicate well with their surroundings.The prevalence of AOB in children and adolescent in our population is unknown. Furthermore, the most frequent type of dyslalias in children with this malocclusion is also unknown. Therefore, the aim of the study was to describe the frequency and types of dyslalia in students between 8-16 years with AOB, as well as the difference in the types of dyslalia according to the magnitude of AOB.MethodsA cross-sectional study was conducted. Clinical assessment of AOB in students from the municipality of Envigado, Colombia, was performed. Students from 8 to16 years of age were examined during the second semester of 2011 and first semester of 2012. Phonoaudiological assessment was carried out in students in the mixed or permanent dentition. Exclusion criteria included children with history of systemic disease, altered skeletal development, neurological and psychiatric disorders, and residents in other departments. In addition, students undergoing orthodontic treatment at the time of evaluation or with history of previous orthodontic treatment, as well as those who did not cooperate with the oral cavity evaluation, were excluded.ResultsSix thousand one hundred sixty five children were evaluated. One hundred sixty six presented AOB (prevalence: 2.7 %; 95 % CI: 2.28–3.10). Thirty four students were excluded. 26.5 % of the sample presented mild AOB, 66.7 % moderate, and 6.8 % severe. Some type of dyslalia was found in 77.4 % of the students, being distortion (75.8 %) the most common. The most frequently altered phonemes were: / d / t / s / ch / ñ /. No significant association between different types of dyslalia and AOB severity (p-value = 0.974) was found.ConclusionPrevalence of AOB in Envigado is low (2.7 %). Phonation alterations are very common in children with AOB (77.8 %), and distortion is the most frequent type of dyslalia (75.8 %). In order to diagnose and treat occlusal and phonetic problems, and to avoid possible recurrence, interdisciplinary approach is recommended.

Comparison between the effects of Daivonex cream alone and its combination with narrowband ultraviolet B in treatment of psoriasis

Introduction: Psoriasis is a chronic immune disorder that multiple factors are involved in its creation. Psoriasis is not curable but a large number of local and systemic treatments for psoriasis are available that can reduce symptoms and recurrence of the disease. Treatment is selected based on severity of illness, associated comorbidities, patient preference[including costs and convenience], and evaluation of the effectiveness of patient response to treatment. Methods: 94 cases included from patients admitted to the Sina dermatology clinic with diagnosis of psoriasis. They were randomly divided in two groups. First group treated with Calcipotriol alone while the second group treated with calcipotriol and NBUVB phototherapy. Results: According to the results of our study the subjects in the two groups in terms of sex, age, weight, height, history of systemic disease, duration of psoriasis, site of involvement and the extent of the lesions were not significantly differ. An average improvement in lesion thickness, erythema and scaling and investment, and improve overall recovery of waste per week in the fourth, eighth and twelfth week after treatment, In the second group were significantly higher than the first group. Conclusion: Daivonex cream in combination with NBUVB phototherapy has a faster and more recovery in a given time. Daivonex with NBUVB phototherapy can be used to provide better results.

A rare manifestation of neuro-ophthalmic sarcoidosis: A case report

PurposeAnterior uveitis is the most common ocular manifestation of sarcoidosis. Ocular involvement affects approximately 30–60% of patients with systemic sarcoidosis; however, optic disc edema is a rare event. We report a patient who presented with a rare case of sarcoidosis with neuro-ophthalmic manifestations. Case reportA 22-year-old man was referred to our clinic with the primary complaint of a visual field defect over the temporal side of his right eye of 2 months duration. He did not have a history of systemic disease. At the first ophthalmic examination, the visual acuity, intraocular pressure, and slit lamp examination were normal. The fundus examination revealed bilateral optic disc edema. He was initially suspected of having a choroidal lesion between the disc and fovea of the right eye. To evaluate the possible lesion, the patient underwent brain magnetic resonance imaging (MRI), chest radiography, and chest computed tomography (CT). There were no abnormalities on the brain MRI, but the chest radiographs and CT images revealed bilateral mediastinal and hilar lymphadenomegaly. Histopathologic evaluation of an ultrasound-guided lymph node biopsy confirmed the diagnosis of sarcoidosis. ConclusionNeuro-ophthalmic manifestations of sarcoidosis are rare but may be the only presenting sign of an otherwise occult disease. A high clinical suspicion for sarcoidosis and its inclusion as a differential diagnosis are key to establishing the diagnosis and proper treatment.

Adult onset dyschomatosis universalis.

Dear Editor: Dyschromatosis universalis hereditaria (DUH) is a rare hereditary skin disorder that is characterized by a mixture of small and irregularly sized hyperpigmented and hypopigmented macules of a mottled or reticulated pattern. The usual onset age of DUH is 6 years1. The common pattern of inheritance is generally autosomal dominant; however, rarely, a few cases show a sporadic pattern. Some authors named this form as dyschromatosis universalis (DU) instead of DUH2. We report a case of DU in a 29-year-old female patient with no family history and a late onset of the disease. A 29-year-old Korean woman presented with asymptomatic multiple pinhead to rice sized mottled hypopigmented macules with diffuse hyperpigmented patches on the abdomen and left upper arm (Fig. 1A). The hyperpigmented lesions, which had been noted 1 year previously, started initially on the abdomen and gradually spread to the left upper arm. She has no history of systemic disease or any previous cutaneous disease. She also denied any family history of skin discoloration or similar skin lesions. Fig. 1 (A) Multiple pinhead to rice sized mottled hypopigmented macules with diffuse hyperpigmented patches. (B) A closer view. (C) A biopsy specimen taken from a hyperpigmented lesion on the abdomen showed increased abundant melanin pigments in the epidermis ... A biopsy specimen taken from the hyperpigmented lesion on the abdomen showed increased abundant melanin pigments in the epidermis, with normal number and distribution of melanocytes on hematoxylin-eosin, Fontana Masson, and MART-1 stainning (Fig. 1B). In contrast, the histopathologic finding of a hypopigmented macule suggested a reduced amount of melanin pigments in the lesion area (Fig. 1C). On the basis of these findings, the diagnosis was concluded to be DU. We recommended treatment with Q-switched Nd:YAG laser for the hyperpigmented lesions; however, she refused the therapy. She has been followed without any changes. Rycroft et al.3 reported a case with no family history, but was associated with short stature and high tone deafness. In addition, Shono amd Toda4 reported a case with no family history and associated with photosensitivity and a neurosensory hearing defect. Also, Kim et al.2 reported a case that occurred in the patient at age 20 years, with a sporadic pattern and with no comorbid conditions. Some authors suggest that DU is a more appropriate name for the sporadic cases rather than DUH2. DU should be differentiated from other conditions showing both hyperpigmentation and hypopigmentation, such as generalized Dowling-Degos disease, xeroderma pigmentosum, dyskeratosis congenita and chronic radiodermatitis. DU generally does not involve a family history and present only dyschromatosis without systemic disorder. Various therapeutic trials, such as psoralen and ultraviolet A irradiation, thin split-thickness skin autograft, and Q-switched ruby laser have been tried to treat these lesions; however, there is no definitely effective treatment for both hyperpigmented and hypopigmented lesions. Recently, Kim et al.5 reported that they successfully treated the hyperpigmented lesions of DUH with a Q-switched Nd:YAG laser. Only a few cases of DU have been reported worldwide, and we could find only three cases in the Korean literature (Table 1)2,3,4. Particularly, adult-onset DU like our case is very unusual. Thus, we here report a case of DU occurring in a 29-year-old female patient with no family history. Table 1 Reported cases of dyschromatosis universalis in global literatures (including Korea)

Effects of Training Program wearing Balance Shoes to Reduce Knee and Lower Extremity Injuries in Junior Athletes: A Randomized Controlled Trial

Objective: The purpose of this randomized controlled trial was to compare the effectiveness of an original 15-minute exercise program wearing the ReaLine Balanceshoes (RBS) and a conventional injury prevention program in reducing lower extremity injuries. Methods: We recruited athletic club teams from local junior high schools. Inclusion criteria were adolescents who were a member of their interscholastic athletic club team. Players with an injury within 6 weeks that prevented full participation in sports, a history of systemic disease or neurologic disorder at the start of the intervention, and those already using an injury prevention program were excluded. Participants were individually randomized within a team into one of the study groups (RBS or control). The RBS group used the RBS, a shoe-type training device designed for correcting dynamic knee valgus. A 6-staged progressive exercise program was developed, including slow closed kinetic chain strengthening, joint realignment, balancing, feedforward, feedback, and plyometric components. The control group performed an injury prevention program previously used to reduce injury risk. One 15-minute session was performed 3 days/week for 12 months. The primary outcome was incidence of anterior cruciate ligament (ACL) injury and acute knee injuries. Results: One hundred twenty three players completed the study (RBS, n=65; control, n=58). No ACL injury or acute knee injury occurred among RBS athletes versus 1 ACL injury [RR 0.298, 95% CI (0.012, 7.175)] and 3 acute knee injuries [RR 0.127, 95%CI (0.007, 2.421)] among control athletes. Conclusion: The RBS program was not significantly more effective than a conventional injury prevention program in reducing the incidence of ACL injury and other acute lower extremity injuries in junior athletes.

Kikuchi-Fujimoto disease: retrospective study of 91 cases and review of the literature.

Kikuchi-Fujimoto disease (KFD) is a rare cause of lymphadenopathy, most often cervical. It has been mainly described in Asia. There are few data available on this disease in Europe. We conducted this retrospective, observational, multicenter study to describe KFD in France and to determine the characteristics of severe forms of the disease and forms associated with systemic lupus erythematosus (SLE). We included 91 cases of KFD, diagnosed between January 1989 and January 2011 in 13 French hospital centers (median age, 30 ± 10.4 yr; 77% female). The ethnic origins of the patients were European (33%), Afro-Caribbean (32%), North African (15.4%), and Asian (13%). Eighteen patients had a history of systemic disease, including 11 with SLE. Lymph node involvement was cervical (90%), often in the context of polyadenopathy (52%), and it was associated with hepatomegaly and splenomegaly in 14.8% of cases. Deeper sites of involvement were noted in 18% of cases. Constitutional signs consisted mainly of fever (67%), asthenia (74.4%), and weight loss (51.2%). Other manifestations included skin rash (32.9%), arthromyalgia (34.1%), 2 cases of aseptic meningitis, and 3 cases of hemophagocytic lymphohistiocytosis. Biological signs included lymphocytopenia (63.8%) and increase of acute phase reactants (56.4%). Antinuclear antibodies (ANAs) and anti-DNA antibodies were present in 45.2% and 18% of the patients sampled, respectively. Concomitant viral infection was detected in 8 patients (8.8%). Systemic corticosteroids were prescribed in 32% of cases, hydroxychloroquine in 17.6%, and intravenous immunoglobulin in 3 patients. The disease course was always favorable. Recurrence was observed in 21% of cases. In the 33 patients with ANA at diagnosis, SLE was known in 11 patients, diagnosed concomitantly in 10 cases and in the year following diagnosis in 2 cases; 6 patients did not have SLE, and 4 patients were lost to follow-up (median follow-up, 19 mo; range, 3–39 mo). The presence of weight loss, arthralgia, skin lesions, and ANA was associated with the development of SLE (p < 0.05). Male sex and lymphopenia were associated with severe forms of KFD (p < 0.05). KFD can occur in all populations, irrespective of ethnic origin. Deep forms are common. An association with SLE should be investigated. A prospective study is required to determine the risk factors for the development of SLE.

Intravenous Antibiotics Impact on Post-ERCP Pancreatitis

Introduction: In a previous report, antibiotic prophylaxis of intravenous ceftazidime given 30 minutes before ERCP decreased the risk of pancreatitis, suggesting that bacteria could play a role in the pathogenesis of post-ERCP pancreatitis (PEP). We aimed to evaluate the role of antibiotics on the incidence of PEP. Methods: A single-center, retrospective, case-control study was conducted to evaluate the potential effect of pre-ERCP intravenous antibiotics (piperacillin and tazobactam, ciprofloxacin and cefoxitin) in preventing PEP. All patients who underwent ERCP between January 2007 and February 2014 were included. Medical records of the patients were reviewed for demographic information, history of systemic disease, smoking, and alcohol abuse. Physician orders and nursing notes were reviewed to confirm intravenous antibiotics use prior to ERCP. PEP was defined based on new onset abdominal pain requiring hospitalization for at least 2 nights and increase in serum lipase and/or amylase ≥3 times the upper limit of the normal level at least 24 hours after the procedure. Results: Two hundred eighty ERCPs were performed during the study period; the average patient age was 63.1 years, with 158 females, and 36 patients with history of pancreatitis. Patients were divided in those taking intravenous antibiotics (n=88) and control group (n=192) who did not take antibiotics. Fifteen patients developed PEP, 7 of 88 patients (7.9%) taking antibiotics and 8 of 192 (4.1%) not taking antibiotics (p=0.205). The following factors were found to be significantly associated with an increased incidence of PEP, history of PEP, female sex, and difficult cannulation/failed attempt. Conclusion: Our study did not show any evidence to support a role for antibiotics (piperacillin and tazobactam, ciprofloxacin, cefoxitin) in decreasing the incidence or severity of PEP.

A Rare Cause of Compression of the Ulnar Nerve Neuritis: Deep Vein Thrombosis

A 21-year-old woman presented to the emergency department with complaint of pain in the right elbow, and ring and pinky finger numbness. The patient had no prior history of systemic disease. The patient reported similar symptoms had occurred intermittently after physical exertion during the previous three months. However, the patient presented at the hospital after experiencing the symptoms while at rest. Physical examination identified a palpable soft mass at the beginning of the third distal humerus and extending to the cubital region on the inner side of the right elbow with the consistency of the dough. The Tinel test was positive. Other system examination findings were normal. The patient's laboratory findings, complete blood count and blood chemistry tests were normal. Magnetic resonance imaging of the patient is shown in Figure 1 and Figure 2a, b. Figure 1 An increase in brachial diameter and thrombus in fat-suppressed proton density T1-weighted MR images sequences at the same level (*). Figure 2 (a) An increase in brachial diameter and thrombus in axial T1-weighted MR images. Thin white arrows: brachial vein filled within thrombus. *: m. pronator teres, **: m. brakialis, black triangles: a. brachialis, curved white arrow: v. basilica, thick white ... DIAGNOSIS: Cubital Tunnel Syndrome Cubital tunnel syndrome (CuTS) is the most common form of entrapment of the ulnar nerve and the second most common nerve compression syndrome of the upper extremities, the most common being carpal tunnel syndrome. The incidence is 24.7 cases per 100,000 person-years; men are affected twice as often as women. Clinical findings include paraesthesia and tingling in the lateral 2 fingers, pain related to the elbow joint, and in severe cases, weakness or atrophy of the intrinsic muscles of the hand.1, 2, 3 Soft tissue masses such as ganglia, lipomas, fibrolipomas, and epidermoid cysts can compress the ulnar nerve as it lies in the condylar groove or within the cubital tunnel. However, it was not reported that the ulnar nerve was wrapped and compressed by the DVT mass. In this respect, the present case has the distinction of being unique. We present the first case of CuTS due to DVT. Magnetic resonance imaging of the patient detected an acute phase deep vein thrombosis (DVT) that could not be compressed, causing an increase in the lumen diameter in the brachial vein and in the right elbow (Figure 1, Figure 2). After cardiovascular surgery, consulting physicians initiated medical treatment with enoxaparine (150 anti-Xa IU/kg, once-daily). Control returned to the patient and the patient was discharged. The patient's symptoms completely resolved three months later.

Wohlfahrtia magnifica’dan Kaynaklanan Gingival Miyaz Olgusu

Myiasis is an infestation of living or dead tissue of humans and animals by diptera larvae. Gingival myiasis is a rare pathology and is mainly associated with poor oral hygiene, alcoholism, senility, suppurative lesions, mouth breathing, mental retardation and hemiplegia. Myiasis is most common during summer since the fly population increases during this season. Mostly it occurs in farmers and people who live in tropical climates. Gingival myiasis in humans in Turkey is limited to only a few cases. According to our literature research, this is the first case of gingival myiasis produced by larvae of Wohlfahrtia magnifica in a Turkish adult. According to our best knowledge, it is also the first gingival myiasis case that one of the causative larva had grown to the adult stage in Turkey. A 43 years old male patient who perceived the presence of live maggots in his mouth was referred to our clinic. Clinical findings of gingival myiasis were observed. The patient had no history of systemic disease but oral hygiene was poor. Clinical and radiographic examination indicated that he had chronic periodontitis. Before the dental treatment seven larvae and during the scalling five larvae were elevated from the gingival sulcus. The body of the larvae composed of 12 segments and they were 8-10 mm in length. One of the larvae which was sent to the microbiology laboratory were placed into sheep liver to resume life and the other larvae were placed into 70% alcohol solution. After 9-10 days, the larva which was placed in the liver became pupa. Approximately 15 days later, the pupa became an adult fly. The larvae were identified as the second stage larvae of Wohlfahrtia magnifica. Treatment consisted of removal of the maggots from the gingival sulcus, followed by scaling and oral hygiene instruction. Non-surgical periodontal treatment was applied and the patient was followed-up for 3 months. After non-surgical periodontal treatment, patient didn't accept the flap operation. The most important point for the prevention of gingival myiasis is to establish a good oral hygiene, together with the elimination of environmental factors which support the proliferation of the flies.

Periodontal health status and salivary parameters in pregnancy

Background: Pregnancy is considered a major risk factor for development and progression of periodontal disease. There are hormonal changes in both estrogen and progesterone hormones in addition to bacterial effect and poor oral hygiene that will enhance development of periodontal disease in pregnant women. Materials and methods: Seventy subjects were enrolled in the study, the subjects with an age range (20-35) years old without any history of systemic disease. The subjects were divided into 20 non-pregnant women they represent the control group (G I), 30 pregnant women with gingivitis (GII) and 20 pregnant women with periodontitis (GIII).All periodontal parameters (plaque index, gingival index, bleeding on probing, probing pocket depth and clinical attachment level) were recorded and 5ml of unstimulated saliva was collected for each subject. The collected saliva was centrifuged and clear supernatant was collected and kept frozen until biochemical analysis of salivary enzymes which included ALP, LDH and salivary Calcium. Results: No significant difference in the mean value of salivary ALP between GI and G II, while there is high significant difference between GI and GIII. There was significant difference in the salivary LDH and Ca levels between control group and group II, while there is highly significant difference of salivary LDH and Ca between group I and group III.There was significant difference in the number of bleeding sites, and probing pocket depth (PPD) among all groups. There was increase in the total number of all scores of PPD (score 1,2 and 3) GII and GIII compared to GI. Conclusions: Thepregnant women revealed more periodontal disease conditions (gingivitis and periodontitis) due to hormonal changes superimposed with microbial infection. Salivary enzymes (ALP, LDH) and salivary calcium are considered as good biochemical markers of periodontal tissue destruction and can be used to evaluate the effect of pregnancy on periodontal health status.

Leukemia Cutis Coexisting With Dermatofibroma as the Initial Presentation of B-cell Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

: Cutaneous involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is often observed in patients with a known history of systemic disease. Rarely, CLL/SLL may initially present with skin lesions. There are also rare reports of cutaneous CLL/SLL occurring in herpes scars and as an incidental finding in excision specimens for carcinoma. We present a 76-year-old woman with an inverted conical firm papule on the upper back that was clinically suggestive of a dermatofibroma. Excisional biopsy demonstrated the presence of a dermatofibroma coexisting with CLL/SLL. We describe the rare occurrence of CLL/SLL initially presenting as leukemia cutis. In addition, to the best of our knowledge, this is the first report of dermatofibroma coexisting with CLL/SLL. This finding further expands the types of skin lesions that may coincide with CLL/SLL.

潰瘍性大腸炎の初期症状として出現した増殖性化膿性口内炎の1例

A case of pyostomatitis vegetans as an initial symptom of ulcerative colitis is reported. A 16-year-old girl with no history of systemic disease was referred to our department because of oral pain. Miliary pustules with a cobblestone appearance and a partial ulcer were found in the bilateral maxillary gingiva and the left mandibular gingiva. Treatment with topical corticosteroids had no effect on the oral lesions. We recommended that the patient sought medical consultation because of fever, diarrhea, and hematochezia. She was given a diagnosis of ulcerative colitis and was prescribed mesalazine by a physician. After treatment, the fever, diarrhea, and hematochezia resolved. On the other hand, the oral lesion expanded and involved the entire mucosa of the mouth. Histopathological examination revealed that the lesion was suppurative inflammation with ulcer formation, diagnosed as pyostomatitis vegetans. Immediately after the systemic administration of corticosteroids began, the oral mucosal lesion resolved.

Non‐dermatophyte mould onychomycosis: a clinical and epidemiological study at a dermatology referral centre in Bogota, Colombia

Worldwide prevalence of non-dermatophyte mould onychomycosis has increased in recent years; however, available information on the topic is confusing and oftentimes contradictory, probably due to the small number of reported cases. The aim of this study was to determine and describe the aetiological agents, as well as the epidemiological and clinical characteristics of non-dermatophyte mould onychomycosis in a dermatology referral centre in Bogota, Colombia. A cross-sectional descriptive study was conducted between January 2001 and December 2011 among patients who attend the National Institute of Dermatology with a confirmed diagnosis of onychomycosis by non-dermatophytes moulds. There were 317 confirmed cases of non-dermatophyte mould onychomycosis in 196 women and 121 men whose average age was 43years. Twenty-seven per cent of them had a history of systemic disease. The habit of walking and showering barefoot was the major infection-related factor. Distal and lateral subungual presentation was the most common pattern of clinical presentation. The most frequent non-dermatophyte mould was Neoscytalidium dimidiatum followed by Fusarium spp. No relationship was observed with predisposing factors previously reported in the literature. Clinical features found in this population are indistinguishable from onychomycosis caused by dermatophytes. High prevalence of N.dimidiatum found here was in contrast to a large number of studies where other types of moulds predominate.

A reticular pigmented rash on the lower leg

A 10-year-old boy presented to the dermatologist for a spider web-like pigmented rash on the lower right leg. On examination it was found that the rash was expanding medially from the lateral aspect of the leg to ventral part of the foot (Figure 1). The left leg was uninvolved. Erythema was not elevated and disappeared on applying pressure to the area. His history revealed that, on advice of his parents, he had been using an electric heater for the past four winter months to keep his legs warm, prior to appearance of the rash. He had no leg pain, abdominal pain, or any history of recurrent fever. There was no history of systemic disease, and physical examination with CBC was within normal limits. A reticular pigmented rash on the lower leg

Factors related to peri‐implantitis – a retrospective study

Retrospectively, we assessed the likelihood that peri-implantitis was associated with a history of systemic disease, periodontitis, and smoking habits. Data on probing pocket depth (PPD), bleeding on probing (BOP), and radiographic bone levels were obtained from individuals with dental implants. Peri-implantitis was defined as described by Sanz & Chapple 2012. Control individuals had healthy conditions or peri-implant mucositis. Information on past history of periodontitis, systemic diseases, and on smoking habits was obtained. One hundred and seventy-two individuals had peri-implantitis (mean age: 68.2years, SD±8.7), and 98 individuals (mean age: 44.7years, SD±15.9) had implant health/peri-implant mucositis. The mean difference in bone level at implants between groups was 3.5mm (SE mean±0.4, 95% CI: 2.8, 4.3, P<0.001). A history of cardiovascular disease was found in 27.3% of individuals with peri-implantitis and in 3.0% of individuals in the implant health/peri-implant mucositis group. When adjusting for age, smoking, and gender, odds ratio (OR) of having peri-implantitis and a history of cardiovascular disease was 8.7 (95% CI: 1.9, 40.3 P<0.006), and odds ratio of having a history of periodontitis was 4.5 (95% CI 2.1, 9.7, P<0.001). Smoking or gender did not significantly contribute to the outcome. In relation to a diagnosis of peri-implantitis, a high likelihood of comorbidity was expressed by a history of periodontitis and a history of cardiovascular disease.

THU0316 Salivary Gland Ultrasonography in Primary SjöGren’s Syndrome. Association with Lymphoma Risk Markers and Longitudinal Follow-Up.

BackgroundPreviously we reported that salivary gland ultrasonography (SGUS) using a simplified score1,2 is a specific but not a sensitive diagnostic method in primary Sjögren’s syndrome (pSS). The purpose of the...

SAT0220 Diagnostic utility and prognostic value of parotid gland ultrasonography in primary sjögren’s syndrome: The classical hypoechogenic pattern of parenchymal abnormality is highly specific, associated with higher disease activity and systemic disease

BackgroundThe diagnosis of primary Sjögren’s Syndrome (pSS) relies on invasive or non-specific tests, such as salivary gland biopsy, sialometry, sialography or scintygraphy. Ultrasonography (US) has become widely available for rheumatologists...

Idiopathic dilated episcleral vessels (Radius-Maumenee syndrome): case report

Radius-Maumenee syndrome comprises idiopathic dilated episcleral vessels that are usually associated with glaucoma. The case described herein is of a male patient, 69 years old, with chronic dilation of the episcleral vessels and glaucoma in his left eye, with no history of systemic disease. Visual acuity and fundoscopy were normal in both eyes. Tonometry measured 14 mmHg in the right eye and 25 mmHg in the left. Computed tomography angiography (CTA) was negative for carotid-cavernous fistula. The intraocular pressure of the left eye decreased to 20 mmHg with clinical treatment without regression of episcleral venous dilation. Trabeculectomy normalized the intraocular pressure and reduced the vessels. There was choroidal effusion on day 16 of the postoperative period, which resolved with corticosteroids. Although choroidal effusion can occur, the efficacy of trabeculectomy in controlling glaucoma and the reduction of episcleral vessels are clearly demonstrated.