History Of Poor Performance Research Articles

Assessing the cardiac valves conditions in athletic horses with poor performance.

Heart murmurs and valvular regurgitation are common in horses and often have no effect on their performance. However, when structural changes occur in the heart size, they can affect performance adversely. This study aimed to examine the correlation between cardiac valves disease and poor performance in athletic horses. A total of 300 athletic Thoroughbred and mix-breed horses including 164 mares and 136 stallions, with a history of poor performance, were selected. Horses with cardiac murmurs were identified and further cardiac examination including precise auscultation, base-apex electrocardiogram for possible dysrhythmias at rest and after exercise, echocardiographic and hematological tests were conducted in two stages. The first was at admission time and the second examination was done four to six months later to evaluate the outcome of the possible disorders. Respiratory system and musculoskeletal diseases were diagnosed respectively in 93 and 149 out of 300 examined horses and 36 horses showed heart murmur without any other complications. Echocardiography was performed in horses with heart murmur and 25 of them showed regurgitation of the cardiac valve. During the first examination, 7 horses were diagnosed with regurgitation and changes in the size of cardiac chambers, whereas this number increased to 25 during the second examination. There was no significant relationship between degree of murmur and severity of regurgitant jet in horses. The valvular regurgitation can affect the performance when causing changes in the size of the cardiac chambers which can consequently jeopardize the athletic future of the horse.

Using heritage building registers to characterise unreinforced masonry buildings of Brisbane, Australia

ABSTRACT Worldwide, unreinforced masonry (URM) buildings are present in abundance with many holding cultural and heritage value. URM buildings have a known history of poor performance during past earthquakes because of the weak tensile properties and lack of mechanical connections between elements. Information about the construction of URM buildings for a region is important because it can help engineers and policy makers to perform seismic assessment, risk and loss studies. In this regard, this study includes a characterisation of the heritage URM buildings in Brisbane City, Australia, and its surrounding suburbs using the Queensland Heritage Register (QHR). The QHR includes a total of 1775 heritage sites, of which 323 are identified as URM buildings in Brisbane City and surrounding suburbs. The studied building characteristics obtained from QHR included the architectural styles, construction year, function/use, number of storeys, roof material and load-bearing wall materials. Other features such as roof types (shapes), plan geometry, isolated or interconnected buildings, verandas and openings, and finally the presence of seismic hazards such as gable-end walls, chimneys, and parapets have been obtained using online 3D maps. It was concluded that heritage registers in combination with online digital resources can be successfully utilised to characterise URM buildings.

Does conventional early life academic excellence predict later life scientific discovery? An assessment of the lives of great medical innovators.

SummaryBackgroundPerhaps, as never before, we need innovators. With our growing population numbers, and with increasing pressures on our education systems, are we in danger of becoming more rigid and formulaic and increasingly inhibiting innovation? When young can we predict who will become the great innovators? For example, in medicine, who will change clinical practice?AimsWe therefore determined to assess whether the current academic excellence approach to medical school entrance would have captured previous great innovators in medicine, assuming that they should all have well fulfilled current entrance requirements.MethodsThe authors assembled a list of 100 great medical innovators which was then approved, rejected or added to by a jury of 12 MD fellows of the Royal Society of Canada. Two reviewers, who had taken both the past and present Medical College Admission Test as part of North American medical school entrance requirements, independently assessed each innovator’s early life educational history in order to predict the innovator’s likely success at medical school entry, assuming excellence in all entrance requirements.ResultsThirty-one percent of the great medical innovators possessed no medical degree and 24% would likely be denied entry to medical school by today’s standards (e.g. had a history of poor performance, failure, dropout or expulsion) with only 24% being guaranteed entry. Even if excellence in only one topic was required, the figure would only rise to 41% certain of medical school entry.ConclusionThese data show that today’s medical school entry standards would have barred many great innovators and raise questions about whether we are losing medical innovators as a consequence. Our findings have important implications for promoting flexibility and innovation for medical education, and for promoting an environment for innovation in general.

Rapid screening for cardiac arrhythmias in competition draft horses

Cardiac arrhythmias may cause decreased performance and sudden death during exercise. Our objectives were: (1) to determine prevalence of unrecognised arrhythmias in a population of competition draft horses by performing short duration screening electrocardiograms (ECGs) at rest; and (2) to assess utility of a commercial handheld device for recording equine ECGs. Owners or trainers of 244 draft horses (age 0.5-16 years), including 82 Percherons, 69 Belgians, 69 Clydesdales, 11 Belgian mules, 8 Shires, and 5 Percheron mules, were queried to determine signalment, performance history, and known arrhythmias. All horses were auscultated for 30 s and ECGs were obtained in 204 horses using a handheld recording device (AliveCor®). ECGs were reviewed for quality and used to determine heart rate (HR) and rhythm. When ECG tracing quality permitted, PQ and QT intervals were also measured. ECGs displaying RR intervals adequate for HR determination and rhythm assessment were recorded from 161 horses (79%) while tracings with consistent P waves, QRS complexes, and T waves were recorded from only 47 horses (23%). Four arrhythmias were detected by both auscultation and ECG: atrial fibrillation (1), premature complexes (1), and second-degree atrioventricular block (2). None of these horses had a history of poor performance or previous recognition of an arrhythmia. The prevalence of unrecognised, and potentially clinically significant, arrhythmias in draft horses at rest appears to be low (2/244; 0.8%, 95% confidence interval 0.1-2.9%). Longer recordings at rest, as well as recordings during and immediately after exercise, would likely have revealed a higher prevalence of arrhythmias.

Clinical investigation of back disorders in horses: A retrospective study (2002-2017).

Background and Aim:Back disorder is an ailment that often affects athletic and riding horses. Despite the rapidly growing equine athletic and equestrian activities, there is no documentation on the nature of equine back disorder (EBD) in Malaysian horses. The purpose of this study was to characterize EBD cases presented to University Veterinary Hospital, Universiti Putra Malaysia, between 2002 and 2017.Materials and Methods:The compilation of data was based on signalment, case history, duration of clinical signs, anatomical location of the pain, method of diagnosis, type of EBD, treatment, and outcome. The diagnosis of EBD was based on a history of poor performance, clinical examination findings, radiography, and, where applicable, necropsy.Results:A total of 181 diagnosed cases of EBDs were identified. The age of horses ranged from 5 to 22 years. The EBD cases were more prevalent in male than female horses and predominantly in geldings (60.77%). Thoroughbred, Arab, Polo pony, and Warmblood also recorded the most EBD cases among breeds. The discipline of horses tended to influence the development of EBDs, with patrolling horses recording the highest frequency. Most EBD cases were of the primary type (92.27%), with the main causes being soft-tissue lesions (57.48%), vertebral lesions (18.56%), tack-associated problems (16.77%), and neurological lesions (7.19%). The common treatments employed were administration of nonsteroidal anti-inflammatory agents, 1 to 3-month rest, warm and cold compression therapy, massage therapy, exercise adjustment, as well as correction of ill-saddle fit.Conclusion:Most EBDs in this study were associated with soft-tissue lesions. Among vertebral lesions, kissing spines were the most common cause of EBDs in horses in Malaysia.

Changes in Blood Parameters in Healthy Horses and Horses With Upper and Lower Respiratory Tract Diseases Undergoing Treadmill Exercise Tests

Exercise tests are useful tools to evaluate the fitness level of horses in training or with a history of poor performance. The aim of this study was to evaluate the differences in blood parameters in three groups of horses undergoing treadmill exercise tests, either to detect the cause of exercise intolerance or to evaluate the level of fitness before a competition. Blood samples were taken from 30 horses before, at the end of, and two hours after a standardized treadmill exercise test, to detect differences in hematological parameters between healthy horses (10, group N), horses with upper (10, group U), and lower airway diseases (10, group L). Packed cell volume, erythrocyte number, hemoglobin, glucose, and total and unconjugated bilirubin concentration were statistically different between the groups, because of increased oxygen demands in respiratory diseases and intravascular hemolysis. This could occur during exercise and is worsened by the increased breakdown of erythrocytes secondary to exercise-induced pulmonary hemorrhage, diagnosed in horses in group L.

Para além dos preços contratados: fatores determinantes da celeridade nas entregas de compras públicas eletrônicas

Resumo Estudos sobre a efetividade das compras públicas frequentemente enfatizam o preço de aquisição. Pouco se sabe, contudo, sobre outras dimensões de desempenho das contratações realizadas pelo governo, incluindo as relações de interdependência entre custo de aquisição e qualidade. Usando a celeridade na entrega como dimensão alternativa de desempenho, este estudo investigou quais são os mecanismos que ajudam a compreender a redução dos preços contratados e dos prazos de entrega dos objetos adquiridos por meio de compras públicas eletrônicas, bem como a influência da economia obtida na fase de licitação sobre a celeridade da entrega. Analisando uma base de dados única, com informações detalhadas de 3.755 processos de compras realizadas por um órgão do governo federal, constatou-se que, embora as licitações eletrônicas sejam eficazes para reduzir preços contratados nos certames de intensa competição, não há relação significativa entre o acirramento da concorrência entre os participantes e a celeridade na entrega. Ademais, os resultados indicam que fornecedores com histórico de desempenho insatisfatório são exatamente aqueles que continuam comprometendo o resultado das compras públicas.

The Openness/Intellect Model on the M5-50: Supporting the Flexibility of IPIP-Based Instruments

This study examined ways to improve fit and interpretive capacity of the M5-50, an IPIP-based personality instrument, using the Openness/Intellect model (O/I) given a history of poor performance of the M5-50 Openness scale (Author, 2013; Socha, Cooper, & McCord, 2010). With participants from Amazon’s MTurk (n = 305), theoretical models for the five-factor model, Openness as a 10-item single factor, and the O/I model were tested and fitted poorly After removing one problematic item, the O/I model showed acceptable fit. Findings indicate that the O/I model improved psychometric validity and interpretive capacity for the M5-50. The flexibility and open access of IPIP-based instruments such as the M5-50 makes the IPIP an optimal choice for instrument adaptation and construction in Latin America.

Prioritization Strategy for Replacing Deteriorating Partial-Depth Precast Concrete Deck Panels in Florida

AbstractPrecast deck panel bridges have a history of poor performance in Florida. In the aftermath of five localized punching shear failures, a decision was made to replace all 127 deck panel bridges in southwest Florida over a 10-year period. This paper describes the strategy used for prioritizing their replacement. Two risk indices focusing on safety and importance were developed for this purpose. The safety index was determined from available inspection records and the importance index from annual daily traffic. Forty-two bridges had already been earmarked for replacement. The 85 remaining bridges were ranked using this protocol; 39 were rated as being in good condition. The replacement order for the remaining 46 bridges was prioritized. The validity of the approach was confirmed by the subsequent localized failure of two bridges, both identified as being at high risk.

Changing Environments by Changing Individuals

The two studies reported here tested whether a classroom-based psychological intervention that benefited a few African American 7th graders could trigger emergent ecological effects that benefited their entire classrooms. Multilevel analyses were conducted on data that previously documented the benefits of values affirmations on African American students’ grades. The density of African American students who received the intervention in each classroom (i.e., treatment density) was used as an independent predictor of grades. Within a classroom, the greater the density of African American students who participated in the intervention exercise, the higher the grades of all classmates on average, regardless of their race or whether they participated in the intervention exercise. Benefits of treatment density were most pronounced among students with a history of poor performance. Results suggest that the benefits of psychological intervention do not end with the individual. Changed individuals can improve their social environments, and such improvements can benefit others regardless of whether they participated in the intervention. These findings have implications for understanding the emergence of ecological consequences from psychological processes.

Long-Term Evaluation of Geosynthetic Reinforcement of Flexible Pavements Constructed over Thick Organic Soil Deposits

Many regions throughout Florida have thick deposits of organic soil. Roadways built over these deposits often exhibit differential settlement, significant rut depths, and extensive cracks in a relatively short period of time. The Florida Department of Transportation constructed an experimental project on a realigned portion of State Road 15 on the southeastern shore of Lake Okeechobee in Palm Beach County to evaluate the effect of geosynthetic reinforcement on pavement performance. This roadway traverses farmlands with deep layers of organic material just beneath the surface and has a history of poor performance. The experimental project included four 500-ft sections with combinations of geogrids and geotextiles placed below the base and above the organic material. A fifth section of similar length was constructed with no geosynthetic reinforcement and served as a control. In addition to geosynthetic reinforcement, the alignment was surcharged before construction. The investigation showed that surcharging alone significantly improved the pavement performance compared with historical pavement condition and rehabilitation records. Geosynthetic reinforcement doubled the equivalent single-axle loads allowed on the unreinforced section. A rigid geogrid or woven geotextile placed below the base appeared to provide a slightly stiffer and better-performing pavement than a flexible geogrid. This paper documents the research program and provides details on the improvement resulting from surcharging and geosynthetic reinforcement.

Diagnostic Exercise

A 9-year-old Thoroughbred gelding presented with a 97-day history of poor performance and intermittent fever. Clinicopathologic changes included increased serum activity of γ-glutamyltransferase and alkaline phosphatase, mild hyperbilirubinemia, and leukocytosis with neutrophilia and lymphopenia. Abdominal ultrasound revealed hepatomegaly with hyperechoic hepatic parenchyma and biliary distention. Pathologic findings included marked hepatomegaly (liver 3.6% of body weight), firm hepatic consistency with a diffuse enhanced reticular pattern, severe portal bridging and sinusoidal fibrosis, oval cell/bile duct hyperplasia, and bile stasis. The differential diagnoses and diagnostic workup to achieve the diagnosis are briefly discussed.

Ataxia due to vertebral hemangiosarcoma with evidence of disseminated disease in a 20-year old Swiss Warmblood mare

A 20-year old Swiss Warmblood mare was referred to the Swiss Institute of Equine Medicine with a history of poor performance, coughing and ataxia and hindlimb weakness which progressed to recumbency. Lung auscultation revealed pronounced wheezing, blood work showed signs of chronic inflammation and increased bone turnover and thoracic ultrasound indicated patchy pulmonary consolidation. Cerebrospinal fluid revealed only mild, unspecific changes allowing exclusion of meningoencephalomyelitis and clinically relevant bleeding. Despite medical treatment and support in a sling the mare did not improve and was euthanized. Necropsy revealed a poorly demarcated, non-encapsulated and invasively growing mass dorsally in the musculature at the level of the forth cervical vertebra (C4) infiltrating the vertebral body and the spinal canal at the level of C1–C2. Multiple nodular, firm masses were present in all lobes of the lung and appeared to be mainly located in vessels. Histologically the masses were composed of spindle cells with marked anisocytosis, anisocaryosis, a high mitotic activity and showed invasive growth. These neoplastic cells stained positive for CD31, an endothelial cell marker, which confirmed diagnosis of a hemangiosarcoma. Definite ante mortem diagnosis of hemangiosarcoma, which is rare in horses, is challenging. Besides the vertebral localization, disseminated, locally invasive and cutaneous forms of hemangiosarcoma exist and can be either acquired or congenital. Prognosis for equine hemangiosarcoma and response to treatment are usually poor and progression of clinical signs is rapid. Vertebral hemangiosarcoma is an uncommon cause of spinal ataxia in horses.

Characterization of Infectious Bursal Disease Viruses Isolated in 2007 from Delmarva Commercial Broiler Chickens

A study was performed in 2007 to isolate and characterize infectious bursal disease viruses (IBDVs) in commercial broilers grown in the Delmarva (DMV) Peninsula region of the United States. Bursae of Fabricius were collected weekly from 1 to 4 wk of age from broilers on 10 farms with a history of poor performance. Microscopic pathology was used to determine the infectious bursal disease (IBD) status of the broilers. Bursae from 1- and 2-wk-old broilers did not show IBD microscopic lesions. Moreover, broilers on 1 of the 10 farms were IBD lesion free at 3 and 4 wk of age. However, 3 of 9 and 9 of 9 farms yielded broilers with IBD-affected bursae from 3- and 4-wk-old commercial broilers, respectively. Ten IBDV isolates were recovered from 3 of 3 lesion-positive bursal pools at 3 wk of age and 7 of 9 lesion-positive bursal pools at 4 wk of age. Analysis of the viral protein (VP) 2 genes identified all isolates as serotype 1 Delaware (Del) variant viruses. Five field isolates, each representing different molecular clades of the Delaware variant viruses, were selected for further study. Experimental infection of specific-pathogen-free white leghorn chickens with isolates DMV/4813/07, DMV/4947/07, DMV/4955/07, DMV/5038/07, and DMV/5041/07 produced gross and microscopic pathology of the bursa consistent with Delaware variant infection. Monoclonal antibody testing showed DMV/4813/07, DMV/4947/07, DMV/ 4955/07, and DMV/5041/07 to be similar to previous recognized variant viruses. However, DMV/5038/07 was found to be unreactive with the monoclonal antibodies that typically recognize reference strains STC, Del E, GLS, RS593, and AL2. In a challenge of immunity study, 10-day-old progeny from breeders immunized with a commercially available inactivated IBDV vaccine containing the Del E and classic strains were protected to a lesser degree against isolate DMV/5038/07 compared to Del E challenge based on microscopic lesion scores (P < 0.01) of the bursa. This result suggests the virus is antigenically different from the Del E strain contained in the vaccine. Collectively, the monoclonal antibody and progeny challenge of immunity findings suggest DMV/5038/07 is antigenically different from the Del E strain contained in the vaccine.

Exercising videoendoscopic evaluation of 7 horses with abnormal respiratory noise and poor performance following partial arytenoidectomy

Summary Exercising upper airway endoscopic evaluation was performed in 7 horses with a history of poor performance after partial arytenoidectomy. Treadmill endoscopy revealed axial deviation of the ipsilateral aryepiglottic fold in all horses. Dynamic collapse of one or more additional upper airway structures was also observed. In 4 horses, laser resection of soft tissue structures that obstructed the upper airway was performed. After laser surgery, 3 horses raced and one performed adequately as a riding horse. Of the remaining 3 horses, 2 raced at a lower class and one performed adequately as a riding horse. In this population of horses, dynamic endoscopy of the upper airway was critical for case management. Based on our observations, horses post arytenoidectomy can have dynamic collapse of the ipsilateral aryepiglottic fold and laser resection of the fold may help resolve the performance problem.

Bacterial pneumonia and pleuropneumonia in sport horses: 17 cases (2001–2003)

SummarySeventeen racehorses were referred with a history of poor performance, recurrent fever, coughing and/or nasal discharge. All patients underwent a thorough diagnostic procedure, including physical examination, complete blood count, plasma fibrinogen estimation, arterial blood gas analysis, thoracic radiology and ultrasonography, endoscopy, tracheal aspiration with cytological and cultural evaluation, including sensitivity test. According to these procedures, bacterial pneumonia was diagnosed in 14 horses and bacterial pleuropneumonia in 3 horses.Streptococcusspp. were isolated in 11 cases (61.2%),Rhodococcus equiin 3 cases (16.6%),Klebsiella pneumoniaein 3 cases (16.6%) andPseudomonas aeruginosain one case (5.6%).

CMS Highlights Special Focus Facilities

CMS Highlights Special Focus Facilities

Back to the Future for African Infrastructure? Why State-Ownership is No More Promising the Second Time Around

Too many African state-owned enterprises (SOEs), particularly those in infrastructure sectors, have a long history of poor performance. African governments and donors labored through the 1970s and 1980s to improve SOE performance through “commercialization”— —i.e., methods short of ownership change. These generally failed, giving rise, in the 1990s, to much more heavy reliance on private sector participation and ownership. This approach produced some successes, but Africa’s private participation in infrastructure (PPI) initiatives have been comparatively few and weak. A number of those that have been launched have run into problems, to the point where both investor and African government interest in the approach has waned in the last few years. The reform is not popular—surveys of public opinion in 15 African countries reveal that only a third of respondents prefer private to stateowned firms. Nonetheless, African states (and their supporters) should not jettison the PPI approach. Rather, they should acknowledge its limitations, and recognize the large scope and moderate pace of the preparatory measures required both to improve their investment climates and to make PPI work effectively.

The Evolution of Enterprise Reform in Africa: From State-Owned Enterprises to Private Participation in Infrastructure - and Back?

Many African state-owned enterprises (SOEs), particularly those in infrastructure, have a long history of poor performance. From the outset, SOE financial and economic performance generally failed to meet the expectations of their creators and funders. By the late 1970s, the situation was alarming, and by early 1980s, critical. The poor financial performance of SOEs became so burdensome to government budgets that it attracted the attention of the international financial institutions, or IFIs. In response, in the 1980s, the World Bank approved SOE reforms that could be summed up in the term commercialization. By the mid-1990s, however, the idea of making SOEs function efficiently and effectively under government management was largely abandoned by the IFIs and privatization and private participation in infrastructure, or PPI became the order of the day. Once more, however, the results were disappointing. PPI has not been as widely adopted as anticipated, nor has it generated the massive resources and changes hoped for, nor has it been widely accepted as beneficial by the African public. The findings of recent studies in Africa suggest that PPI should not be jettisoned, and that the more productive path is to recognize the limitations of the approach, and to work harder at creating the conditions needed to make it function effectively. This will entail, as many have recognized, an end to the view that public and private infrastructure provision is a dichotomy - a case of either-or, one or the other - and a better appreciation of the extent to which the performance of each is dependent on the competence of the other. In other words, for the private sector to perform well, public sector capacity must be enhanced. Moreover, proposed tactics of reform should fit more closely with the expectations and sentiments of the affected government, consumer base, and general population. This broader approach implies, probably, a reduction in the scope and, certainly, a reduction in the planned speed of operations. Improving infrastructure performance is a long-term matter.

Upper Airway Dysfunction Associated with Collapse of the Apex of the Corniculate Process of the Left Arytenoid Cartilage During Exercise in 15 Horses

To report dynamic collapse of the apex of the left corniculate process under the right corniculate process into the airway at the dorsal apposition of the paired arytenoid cartilages during exercise as a cause of upper airway dysfunction in horses. Retrospective study. Fifteen horses with a history of poor performance and/or upper respiratory tract noise during exercise. Video recordings of all horses referred for upper airway evaluation using high-speed treadmill videoendoscopy (HSTV) between January 1998 and December 2003 were reviewed. Records of horses that developed dynamic collapse of the apex of the left corniculate process into the airway were included. Clinical history, age, gender, breed, and use of the horse were retrieved. Of 309 horses referred for examination for poor performance and/or upper respiratory tract noise during exercise, 15 (4.9%) had collapse of the apex of the left corniculate process under the right and into the airway at the dorsal apposition between the paired arytenoid cartilages during HSTV. There were 3 females and 13 males, aged from 2 to 5 years. Five horses had previous surgery for left recurrent laryngeal neuropathy (RLN): 2 had nerve muscle pedicle graft and 3 had laryngeal prosthesis. During HSTV, all 15 horses had progressive collapse of the apex of the left corniculate process under the right at the dorsal apposition of the 2 arytenoid cartilages, and into the dorsal aspect of the rima glottidis. Review of video recordings revealed that collapse of the apex of the corniculate process was followed by progressive collapse of the left aryepiglottic fold and left vocal fold. The ventral aspect of the left corniculate cartilage maintained abduction in all horses. Two horses also had progressive collapse of the right vocal fold, 1 had rostral displacement of the palatopharyngeal arch, and another had dorsal displacement of the soft palate. Dynamic collapse of the apex of the left corniculate process of the arytenoid cartilage under the right is an uncommon cause of upper airway dysfunction in horses and the pathogenesis is unclear. We speculate that the left arytenoideus transversus muscle is unable to support the dorsal apposition between the arytenoid cartilages. This loss of support allows the elastic cartilage of the left corniculate process to collapse under the right and into the airway, as inspiratory pressure increases during exercise. This condition may be associated with an unusually advanced neuropathy of the adductor components of the left recurrent laryngeal nerve and may be an unusual manifestation of RLN; however, this is speculative and further investigation is required to determine its cause. Dynamic collapse of the apex of the left corniculate process and into the airway at the dorsal apposition between the paired arytenoid cartilages can only be diagnosed during HSTV. It is an uncommon cause of upper airway dysfunction but may affect the athletic potential of racing Thoroughbreds and Standardbreds.