Collection Of Historical Data Research Articles

Evaluation of the clinical efficacy of anti-inflammatory therapy with topical biclotymol-based products

Topicality: Acute pharyngeal diseases are one of the most common reasons for patients to visit a doctor. According to the UK, approximately 50% of these diseases account for the appointment of antibacterial agents. Most of these prescriptions are not rational, but doctors use them for several reasons - unreal expectations of treatment, patient pressure/insistence on conducting the desired tests or treatment, the doctor's desire to maintain a better doctor-patient relationship, limited consultation time, diagnostic uncertainty, incorrect collection of historical data and others. Despite these reasons, patients with acute pharyngitis and tonsillitis who seek antibiotic therapy want to reduce their symptoms. Therefore, the search for agents that will significantly improve patients' quality of life during acute pharyngeal diseases is crit ical. Aim: To review the literature on the therapeutic efficacy of topical biclotymol-based products for treating acute pharyngeal diseases. Results and discussion: Most cases of acute pharyngitis should be treated with over-the-counter medicines that are primarily intended to control the symptoms of the disease and improve the patient's quality of life. Biclotymol, enoxolone and lysozyme are novel substances that, at the same time, are safe for resolving pain in viral or bacterial pharyngit is. Biclotymol can be used as monotherapy and in combination with other agents. In the analysed data, biclotymol showed its therapeutic efficacy and safety. Therefore, it is safe to recommend biclotymolbased products for use in acute viral and bacterial pharyngitis or tonsillitis both as monocomponent medicine and fixed-dose combination.

Trends and Patterns of Social History Data Collection Within an Electronic Health Record.

There is increased acceptance that social and behavioral determinants of health (SBDH) impact health outcomes, but electronic health records (EHRs) are not always set up to capture the full range of SBDH variables in a systematic manner. The purpose of this study was to explore rates and trends of social history (SH) data collection-1 element of SBDH-in a structured portion of an EHR within a large academic integrated delivery system. EHR data for individuals with at least 1 visit in 2017 were included in this study. Completeness rates were calculated for how often SBDH variable was assessed and documented. Logistic regressions identified factors associated with assessment rates for each variable. A total of 44,166 study patients had at least 1 SH variable present. Tobacco use and alcohol use were the most frequently captured SH variables. Black individuals were more likely to have their alcohol use assessed (odds ratio [OR] 1.21) compared with White individuals, whereas White individuals were more likely to have their "smokeless tobacco use" assessed (OR 0.92). There were also differences between insurance types. Drug use was more likely to be assessed in the Medicaid population for individuals who were single (OR 0.95) compared with the commercial population (OR 1.05). SH variable assessment is inconsistent, which makes use of EHR data difficult to gain better understanding of the impact of SBDH on health outcomes. Standards and guidelines on how and why to collect SBDH information within the EHR are needed.

Boundaries for genotype, phenotype, and pedigree truncation in genomic evaluations in pigs.

Historical data collection for genetic evaluation purposes is a common practice in animal populations; however, the larger the dataset, the higher the computing power needed to perform the analyses. Also, fitting the same model to historical and recent data may be inappropriate. Data truncation can reduce the number of equations to solve, consequently decreasing computing costs; however, the large volume of genotypes is responsible for most of the increase in computations. This study aimed to assess the impact of removing genotypes along with phenotypes and pedigree on the computing performance, reliability, and inflation of GEBV from ssGBLUP for selection candidates. Data from two pig lines, a terminal sire (L1) and a maternal line (L2), were analyzed in this study. Four analyses were implemented: growth and "weaning to finish" mortality on L1, pre-weaning and reproductive traits on L2. Four genotype removal scenarios were proposed: removing genotyped animals without phenotypes and progeny (noInfo), removing genotyped animals based on birth year (Age), the combination of noInfo and Age scenarios (noInfo + Age), and no genotype removal (AllGen). In all scenarios, phenotypes were removed, based on birth year, and three pedigree depths were tested: two and three generations traced back and using the entire pedigree. The full dataset contained 1,452,257 phenotypes for growth traits, 324,397 for weaning to finish mortality, 517,446 for pre-weaning traits, and 7,853,629 for reproductive traits in pure and crossbred pigs. Pedigree files for lines L1 and L2 comprised 3,601,369 and 11,240,865 animals, of which 168,734 and 170,121 were genotyped, respectively. In each truncation scenario, the linear regression method was used to assess the reliability and dispersion of GEBV for genotyped parents (born after 2019). The number of years of data that could be removed without harming reliability depended on the number of records, type of analyses (multitrait vs. single trait), the heritability of the trait, and data structure. All scenarios had similar reliabilities, except for noInfo, which performed better in the growth analysis. Based on the data used in this study, considering the last ten years of phenotypes, tracing three generations back in the pedigree, and removing genotyped animals not contributing own or progeny phenotypes, increases computing efficiency with no change in the ability to predict breeding values.

Data collection and outcome measurement in student counseling services in Irish higher education institutions: Counselors’ views on challenges and facilitators.

With increasing concerns around student mental health, student counseling services (SCSs) in higher education are being challenged to show evidence of their contribution to the personal and academic development of students through evidence-based approaches including systematic data collection and standardized outcome measurement. This study aims to document data collection and measurement processes in SCSs in higher education institutions (HEIs) in Ireland and to explore the opinions of staff in SCSs on the feasibility and functionality of a standardized national database for SCSs to enhance robust data collection and measurement across the sector. Twenty-three interviews were conducted and thematically analyzed with staff in SCSs in 22 HEIs (85% of publicly funded HEIs). Findings revealed that the process of data collection in SCSs is mainly focused on individual counseling with variations among SCSs in collecting clients' demography, presenting issues, and clinical and educational outcomes. Lack of human and financial resources, no access to an electronic data management system, negative opinions about standardized outcome measures, and concerns over data protection and misuse of data were impeding factors for systematic data collection in SCSs. There is strong support among SCSs for the establishment of a national database which is facilitated by secured funding from the Higher Education Authority, a strong sense of community and trust among student counselors, and a history of data collection through the Psychological Counsellors in Higher Education Ireland association. Findings offer insights into challenges and facilitators for robust data collection and measurement at a national level. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Production Planning to Meet Maximum Demand with Forecasting and Aggregation Methods

Production carried out by small industries still needs to be improved and classified as insufficient compared to the consumer demand. The company’s production traditionally relies on sunlight in the drying process. This is the main factor in the limited production process that can be carried out. This study aims to overcome the maximum demand, which is still an obstacle for the industry to meet their demands. To overcome this, demand forecasting is carried out to determine the demand forecast in advance, and production adjustments are made to meet maximum demand with aggregate planning. Data collection techniques in this study used 1) interview methods and 2) collection of request history data. Data analysis techniques use tools, namely forecasting and aggregate methods. The stages carried out in this study are 1) identification of demand patterns, 2) quantitative forecasting calculations, 3) error analysis, and adjustment of production quantities. This study shows that the maximum consumer demand can be met by procuring supplies in preparation for peak demand.

A Robust Chronic Kidney Disease Classifier Using Machine Learning

Clinical support systems are affected by the issue of high variance in terms of chronic disorder prognosis. This uncertainty is one of the principal causes for the demise of large populations around the world suffering from some fatal diseases such as chronic kidney disease (CKD). Due to this reason, the diagnosis of this disease is of great concern for healthcare systems. In such a case, machine learning can be used as an effective tool to reduce the randomness in clinical decision making. Conventional methods for the detection of chronic kidney disease are not always accurate because of their high degree of dependency on several sets of biological attributes. Machine learning is the process of training a machine using a vast collection of historical data for the purpose of intelligent classification. This work aims at developing a machine-learning model that can use a publicly available data to forecast the occurrence of chronic kidney disease. A set of data preprocessing steps were performed on this dataset in order to construct a generic model. This set of steps includes the appropriate imputation of missing data points, along with the balancing of data using the SMOTE algorithm and the scaling of the features. A statistical technique, namely, the chi-squared test, is used for the extraction of the least-required set of adequate and highly correlated features to the output. For the model training, a stack of supervised-learning techniques is used for the development of a robust machine-learning model. Out of all the applied learning techniques, support vector machine (SVM) and random forest (RF) achieved the lowest false-negative rates and test accuracy, equal to 99.33% and 98.67%, respectively. However, SVM achieved better results than RF did when validated with 10-fold cross-validation.

AKTUALISASI MODERASI BERAGAMA DALAM PENGEMBANGAN KURIKULUM PAI BERBASIS MERDEKA BELAJAR

This study aimed to learn how the implementation of religious moderation in the development of the PAI curriculum. Researchers used the Library Research research method with historical analysis research types and data collection techniques taken from various literature that discussed the theme in question to find out this. The data that has been collected is then analyzed using content analysis techniques. The study results reveal that the inculcation of moderation values ​​in education is so important in managing world civilization in the field of education. With a high sense of tolerance, will not blame differences. However, this does not mean that moderate Islamic teachings are wishy-washy. Still, these teachings will filter out existing disputes and unite the differences that divide the archipelago, nation and religion. Religious moderation in schools can be done through the Hidden Curriculum. The process of acculturation through the habit of internalization and institutionalization. The PAI curriculum now also uses the independent learning curriculum where the aim of the Free Learning curriculum is the policy of the Minister of Education and Culture to encourage students to master useful knowledge. and provide opportunities for students to be free but still express learning within existing limits and criticisms, without having to fade away as noble ideals and also morals for educators. The factors that influence religious moderation in schools include internal and external factors.

Digitization of 20 years of decametric observations of the Sun and Jupiter in Nançay between 1970 and 1990

Since 1970, decametric observations of the Sun and Jupiter have been acquired on a daily basis from the radio observatory of Nançay, France. The resulting database now forms the worldwide largest set of low frequency observations of the Solar Corona between 10 and 100 MHz and of the Jovian magnetosphere between 10 and 40 MHz. The Nançay Decameter Interferometer (NDI), a two-antenna interferometer, acquired pioneer observations from 1970 to 1978, using analog radio receivers tested on the Arecibo giant radiotelescope. The large Nançay Decameter array (NDA), a phased array of 144 helical antennas, was then constructed in the late 1970s as a ground-based support to the Voyager mission and started routine observations in January 1978 in replacement of the NDI, using similar spectrometers. The NDA is still in operation today and its observations, recorded in a digital format since 1990, are public and daily made accessible to the heliospheric and magnetospheric communities at https://www.obs-nancay.fr/reseau-decametrique/. Before 1990, though, the Nançay decametric observations were recorded on analog devices, such as 35-mm films, magnetic tapes and other paper supports, physically archived at the Observatory of Paris, on its site of the Observatory of Meudon, where they could only be accessed on demand. The NDA team recently undertook a multi-year effort to inventory all the Nançay decametric archives, to refurbish and digitize them in order to preserve and promote this historical data collection, most notably by extending the current public database over the 1970–1990 time interval. We digitized the full collection of 35-mm films, corresponding to a total film length of ∼45.5 km, with a specific high resolution scanner. Each roll was scanned by a series of pixel-to-pixel contiguous images recorded in TIF format with adequate metadata and naming convention. The final ∼40 Tb data volume was archived at Paris Astronomical Data Centre and the physical films were refurbished to be archived in a perennial way. We also digitized the associated observations sheets. Finally, we took advantage of this project to also digitize a sample of 35-mm films extracted from four other historical solar data collections hosted at the Observatory of Paris and dealing with two distinct Nançay radiotelescopes and two Lyot heliographs located at the Observatories of Meudon and Haute-Provence. The digitized, documented, Nançay decametric archives have been publicly released to the community in 2020 at http://archives-decametriques.obspm.fr. After having described the instruments, the data collections and the digitization pipeline, this articles ends with a few scientific case studies, focussing on the search for Jupiter-satellite decametric emissions. For instance, the digitized NDA archives suggest the presence of Gan-A and B emissions, while these were first reported in 2018. This work is a concrete example of how historical astronomical measurements can be preserved and archived along the IAU recommendation, to the benefit of the astronomical community.

High Prevalence of Demodex Infestation is Associated With Poor Blood Glucose Control in Type 2 Diabetes Mellitus: A Cross-Sectional Study in the Guangzhou Diabetic Eye Study.

The aim of this study was to investigate the association between type 2 diabetes mellitus (T2DM) and ocular Demodex mite infection. About 381 patients with T2DM from nearby communities were enrolled, and 163 age-matched and sex-matched nondiabetic patients from the cataract clinic were included as the control group. All subjects underwent personal history and demographic data collection, ocular examination, and lash sampling, followed by microscopic identification and counting of Demodex mites. Binocular fundus photography was performed for diabetic patients. Statistical correlation between ocular Demodex infestation and T2DM and blood glucose control status was performed. The Demodex mite infestation rate (62.5% vs. 44.8%, P < 0.001) and count [3 (0-12) vs. 2 (0-9.6), P = 0.01], especially of Demodex brevis (18.9% vs. 4.9%, P < 0.001) [0 (0-1) vs. 0 (0-0), P < 0.001], were significantly higher in the T2DM patient group than that in the control group. The ratio of Demodex brevis to Demodex folliculorum in the T2DM patient group was significantly higher than that in the control group (1:3 vs. 1:9, P < 0.001). Diabetic patients presented with more cylindrical dandruff (55.1% vs. 39.3%, P = 0.001). Ocular Demodex infestation was strongly associated with poor blood glucose control (HbA 1 c > 7%) (odds ratio = 1.82; 95% confidence interval, 1.12-2.94; P = 0.2) and female sex (odds ratio = 1.69, 95% confidence interval, 1.08-2.65, P = 0.02). No association was found between Demodex infestation and the severity of diabetic retinopathy. Patients with T2DM, especially those with poor blood glucose control, tend to have a higher prevalence of ocular Demodex infestation, suggesting that high blood glucose is a risk factor for demodicosis .

Racial Geographies of Land and Domestic Service in Panama

Foreign land control and Afro-Panamanian women domestics are mutually constituted and embedded in tourism development in Panama. In this article, I center the racial and patriarchal logics of dispossession informing land control, a process that connects twenty-first-century residential tourism development to twentieth-century U.S. imperial formations in the making of the Panama Canal. My approach blends ethnographic research with historical data collection, newspapers, and development-related policy documents drawn across a variety of research sites in Panama, Spain, and North America. To begin, I briefly trace the contemporary context of tourism-induced land dispossession and the growing tenure insecurities for Afro-Panamanian communities living on the shores of the Panamanian Caribbean. Here I show how residential tourism development reproduces settler colonial landscapes. Further, I place in conversation the concepts of postcolonial intersectionality and cuerpo-territorio (Cabnal 2015) to illustrate how land control and domestic service are interconnected, punctuating how land is not the only site of colonial governance. I then historicize tourism in Panama through tracing the discursive narratives of imperial formations in the early period of U.S. empire and the construction of the Panama Canal. I trace elite travel narratives, newspapers, and memoirs to link the racialized labor regimes of the Canal to the domestic spaces of the Canal Zone. Finally, I argue that foreign land acquisitions and domestic service are inextricably entangled in tourism development across time and space in Panama.

Perceived discrimination and cognition in a middle age, racially diverse cohort

AbstractBackgroundRisk factors for Alzheimer’s disease (AD) include biologic (e.g. vascular), economic, and socio‐cultural factors. AD incidence and prevalence has been linked to race, and African American/Black individuals (AA/B) are at greater risk compared to non‐Hispanic Whites (NHW), due to physiological and social factors, however few clinical research studies are dedicated to prospective and thoughtful data collection on both physiology (biomarkers) and social/structural risk factors, including discrimination.MethodsWe enrolled 49 middle‐age, cognitively normal B/AA (n = 29) and NHW (n = 20) participants with a family history of AD, and examined correlations between cognition and a perceived discrimination. Cognitive assessments included tests of global cognition, executive function, verbal and visuospatial memory, and language. Six discrimination factors were derived from a larger battery of individually validated assessments of perceived discrimination including, Expanded Everyday Discrimination (EED), Major Experiences of Discrimination (MED), Chronic Work Discrimination and Harassment (WORK), and the Heightened Vigilance (HVIGIL). Factor scores derived from these assessments included ‘Disrespect’, ‘Aggression’, ‘Housing’, ‘Avoidance’, ‘Professional’, and ‘Personal’. Models controlled for education, income, race, and age.ResultsPerceived discrimination had an influence on cognitive scores in a race‐independent manner in this cohort. It was also found that this relationship maybe stratified by educational level. Participants were mostly women (73.5%) highly educated (42.9% post‐Graduate education) and B/AA participants reported more perceived discrimination compared to NHWs across all 6 composite discrimination factors. We observed a positive association between episodic memory score and the 'housing’ discrimination factor (p = 0.34 (0.03)), such that increased housing discrimination was associated with increased cognition. A negative correlation was observed between working memory and the discrimination factor ‘Professional’ (p = ‐0.3 (0.05)).ConclusionDiscrimination negatively affects health outcomes and disease risk. Here we report a negative correlation between working memory and ‘professional’ factor score. We also report a positive correlation between cognition and housing discrimination. This latter is likely explained by the relationship between discrimination and geographic mobility, highlighting the presence of systemic and situational racism across all levels of socioeconomic status. Future AD research should incorporate historical and current data collection on redlining, Area Deprivation Index (ADI), and social and housing mobility.

The Australian New Zealand Spontaneous Coronary Artery Dissection (ANZ-SCAD) Registry - A Multi-Centre Cohort Study: Protocol, Background and Significance.

Spontaneous coronary artery dissection (SCAD) is an under-recognised cause of acute coronary syndrome (ACS) with a strong female predominance. There are currently limited prospective studies and no randomised controlled trials that inform on SCAD's best clinical care. Little is also known about predictors of acute SCAD deterioration or recurrence. We describe the study design of a multi-centre prospective and historical cohort study recruiting patients with SCAD across 15-20 sites in Australia/New Zealand (NZ). The primary aim is to describe the clinical presentation, management and outcomes along with predictors of acute deterioration and recurrence in a large Australian/NZ SCAD cohort, with international data pooling. Consented patients diagnosed with SCAD during a hospital admission for an ACS will be prospectively followed at 30 days then yearly, for up to 5 years. Each recruiting site will also retrospectively identify historical cases of SCAD from the proceeding 10 years, with a waiver of consent. For historical cases, data will be collected in a de-identified manner with date of last follow-up or death obtained from the medical records. All cases undergo core laboratory adjudication of coronary angiography and any accompanying imaging to confirm SCAD diagnosis. The primary endpoint will be occurrence of major adverse cardiovascular events; a composite of all-cause mortality, recurrent myocardial infarction (including SCAD recurrence), stroke/transient ischaemic attack, heart failure, cardiogenic shock, cardiac arrest/ventricular arrhythmia, heart transplantation and, repeat/unplanned revascularisation. Secondary endpoints will include each individual primary outcome as well as acute SCAD extension and quality of life/Seattle Angina Score in prospectively recruited participants. Endpoints will be assessed at the end of the hospital admission and at 30-days, 1 year, and median long-term follow-up. Multicentre ethics approval has been granted from the Western Sydney Local Health District Human Research Ethics Committee (2021/ETH00040). The analysed results will be published in peer-reviewed journals on completion of the historical data collection and then on completion of the prospective data collection. The ANZ-SCAD registry has been prospectively registered with the Australia and New Zealand Clinical Trials Registry (ACTRN12621000824864).

Risk factors for heart failure in patients with COVID-19

Aim. To establish risk factors for heart failure (HF) in patients with coronavirus disease 2019 (COVID-19).Material and methods. Medical records of 151 patients treated in an infectious disease hospital from November 3, 2020 to February 2, 2021 with a confirmed diagnosis of COVID-19 were retrospectively selected. The collection of clinical, history and laboratory data were carried out by analyzing electronic medical records. We analyzed information on age, sex, body mass index, smoking, and comorbidities. Following laboratory studies were analyzed: complete blood count, biochemical blood tests, coagulation profile, acute phase proteins (C-reactive protein (CRP), ferritin, lactate dehydrogenase (LDH)), procalcitonin. The diagnosis of HF was confirmed by clinical performance, echocardiography, and elevated levels of the N-terminal pro-brain natriuretic peptide (NT-proBNP). The risk of HF was taken as the endpoint of the study.Results. The studied sample of patients was divided into two groups depending on HF: the 1st group included 46 patients with HF, the 2nd group — 105 patients without HF. The median age was 66,2 (50-92) years (women, 91 (60,3%)). Laboratory indicators, such as the levels of CRP, LDH, procalcitonin, creatinine, bilirubin, differed significantly from each other, and the median values were higher in patients with HF. The neutrophil-to-lymphocyte ratio (NLR) showed significant intergroup differences: in the group of patients with HF, the median was 4,97% vs 3,62% (p=0,011) in the group of patients without HF. There were following most significant predictors increasing the HF risk: age ≥66 years (odds ratio, 8,038, p&lt;0,001), procalcitonin level, which increases the HF risk in patients by 3,8 times (p&gt;&lt;0,001), NLR ≥4,11% (p=0,010), thrombocytopenia ≤220×109/l (p=0,010), history of chronic kidney disease (CKD) (p=0,018). Conclusion. The following predictors of HF were established: age ≥66 years, procalcitonin ≥0,09 ng/ml, NLR ≥4,11%, thrombocytopenia ≤220×109/l, history of CKD, LDH ≥685 U/l and creatinine ≥102 µmol/l, international normalized ratio ≥1,19, QTc interval ≥407,5 ms, bilirubin ≤10,7 µmol/l. It is worth noting that the best accuracy values are demonstrated by the Random Forest algorithm (88,5% on the validation set), but the mathematical model of the neural network turned out to be the most sensitive (90,0% on the validation set). Keywords: novel coronavirus infection, heart failure, prognosis&gt;˂0,001), procalcitonin level, which increases the HF risk in patients by 3,8 times (p˂0,001), NLR ≥4,11% (p=0,010), thrombocytopenia ≤220×109/l (p=0,010), history of chronic kidney disease (CKD) (p=0,018).Conclusion. The following predictors of HF were established: age ≥66 years, procalcitonin ≥0,09 ng/ml, NLR ≥4,11%, thrombocytopenia ≤220×109/l, history of CKD, LDH ≥685 U/l and creatinine ≥102 µmol/l, international normalized ratio ≥1,19, QTc interval ≥407,5 ms, bilirubin ≤10,7 µmol/l. It is worth noting that the best accuracy values are demonstrated by the Random Forest algorithm (88,5% on the validation set), but the mathematical model of the neural network turned out to be the most sensitive (90,0% on the validation set).

The Evolutionary Process and Mechanism of Cultural Landscapes: An Integrated Perspective of Landscape Ecology and Evolutionary Economic Geography

Cultural landscapes are joint masterpieces of man and nature with outstanding universal value. Adequate knowledge of their evolutionary process and mechanism is crucial to their development, protection, and management. However, theoretical understanding about such has been limited as existing studies tend to focus on the descriptive and interpretative analysis of the evolutionary process and pay less attention to the underlying mechanism of the process. Integrating the traditional perspective of landscape ecology in cultural landscape research and theories of path dependence and path creation in evolutionary economic geography, this paper constructs a triple-layered integrated analytical framework of cultural landscape evolution and applies the framework to empirically examine the cultural landscape evolution of Mount Lushan. To grasp an accurate and full picture of the process, field observation and historical data collection were carried out, and a combination of thematic analysis and chronological organization was conducted. The research finds that the cultural landscape evolution of Mount Lushan has experienced three stages, i.e., coexistence and mutual influence of multiple cultures, conflict and integration of Chinese and Western cultures, as well as landscape transformation, revival, and expansion. Such evolution is a non-linear, dynamic, and complex process across which the elements, functions, and patterns of landscapes were constantly constructed and reconstructed. Fundamentally, it is the result of the synergistic effect of path dependence and path creation, and is driven by the interplay of the behavior of associated actors and the change of contextuality. The findings of this study can provide some strategic references for the management practice of cultural landscape heritage sites.

Do privacy assurances work? a study of truthfulness in healthcare history data collection.

Patients often provide untruthful information about their health to avoid embarrassment, evade treatment, or prevent financial loss. Privacy disclosures (e.g. HIPAA) intended to dissuade privacy concerns may actually increase patient lying. We used new mouse tracking-based technology to detect lies through mouse movement (distance and time to response) and patient answer adjustment in an online controlled study of 611 potential patients, randomly assigned to one of six treatments. Treatments differed in the notices patients received before health information was requested, including notices about privacy, benefits of truthful disclosure, and risks of inaccurate disclosure. Increased time or distance of device mouse movement and greater adjustment of answers indicate less truthfulness. Mouse tracking revealed a significant overall effect (p&lt;0.001) by treatment on the time to reach their final choice. The control took the least time indicating greater truthfulness and the privacy + risk group took the longest indicating least truthfulness. Privacy, risk, and benefit disclosure statements led to greater lying. These differences were moderated by gender. Mouse tracking results largely confirmed the answer adjustment lie detection method with an overall treatment effect (p &lt; .0001) and gender differences (p &lt; .0001) on truthfulness. Privacy notices led to decreased patient honesty. Privacy notices should perhaps be administered well before personal health disclosure is requested to minimize patient untruthfulness. Mouse tracking and answer adjustment appear to be health care lie-detection methods to enhance optimal diagnosis and treatment.

Participatory Historical Village Landscape Analysis Using a Virtual Globe-Based 3D PGIS: Guizhou, China

The analysis of historical village landscape characteristics and the influential driving factors of their evolutions can provide an essential decision-making basis for rural sustainable development strategies and landscape planning. How to obtain historical village landscape data at a time when objectively recorded data, such as remote sensing images, were unavailable is a key problem that restricts the analysis of village landscape evolution characteristics. As local villagers are important knowledge sources regarding historical village landscapes, a participatory data collection and analysis approach was used for village historical landscape data in this paper using a virtual globe-based three-dimensional participatory geographic information system (3D PGIS). Taking Duimengshan village, Guizhou, China, as a case study, the 3D landscape of the Duimengshan village and corresponding major historical events in four historical periods, 1958, 1980, 1995, and 2015, were collected in an on-site, interactive way by researchers with the participation of local villagers, and its land-use structure, ecosystem service values, and landscape pattern were analyzed. The results show that the historical landscapes in the four periods were strongly related to important local historical events. The 3D PGIS greatly mobilized the enthusiasm of villagers to participate with its intuitive 3D display form and simple and easy-to-use operation mode. It can be concluded that the historical landscape memory of local villagers and the oral inheritance information handed down from generation to generation can be utilized to make up for the lack of remote sensing and other objective data in the collection and acquisition of historical village landscape data. The obtained historical village landscape characteristics and their evolution laws can be used in future participatory rural planning and landscape design.

Comics As a Tool for Research on Gender Violence. Interview With Nayanika Mookherjee on the Graphic Novel Birangona. Towards Ethical Testimonies of Sexual Violence During Conflict (2019)

Comics and the recently emerged graphic novel format are among the art forms that researchers have chosen to disseminate and provide a visual representation of their work. This relationship between comics and research, which is part of a practice labelled as “arts-based research”, has been facilitated by comics’ recognised narrative and didactic abilities. Research on gender-based violence has not been deaf to the call of comics art, and, in some rare but interesting cases, it has exploited the features of the medium to visualise and circulate research findings. An example is the graphic novel Birangona (Mookherjee &amp; Najmun Nahar, 2019 Durham University), authored by the researcher Nayanika Mookherjee and by the comics artist Najmun Nahar Keya, which was circulated, both in an online and paper version, with the aim of popularizing a set of guidelines on how to conduct oral history data collection with survivors of wartime rape. This interview with Professor Nayanika Mookherjee, the co-author of the graphic novel and the anthropologist who conducted the research with wartime rape testimonies from which the guidelines were taken, has the objective of presenting the arts-based research project Birangona and discussing, in a scholarly fashion, the implementation of visual arts methodologies (and comics-based methodologies in particular) to research gender violence.

FP.39 An international retrospective early natural history study of LAMA2-related dystrophies

<i>LAMA2</i>-related dystrophies (LAMA2-RDs), caused by recessively inherited mutations in the <i>LAMA2</i> gene, represent one of the most common forms of congenital muscular dystrophy and are characterized by a complete or partial deficiency of laminin-211 (merosin). Patients with LAMA2-RDs presenting congenitally typically have a phenotype of severe weakness, delayed motor milestones, failure to thrive and progressive respiratory insufficiency. While a comprehensive prospective natural history study has been performed in LAMA2-RD patients >5 years, the early natural history of patients with LAMA2-RD 5 years and younger has not been comprehensively characterized. Extracting data from the CMD international registry, we describe a cohort of 62 patients with LAMA2-RD from 10 countries. Data for ages birth-5 years was retrospectively collected from the medical records. Inclusion criteria required that the patients had either two causative <i>LAMA2</i> variants or one confirmed causative <i>LAMA2</i> variant and a supporting clinical phenotype. Initial analyses reveal key findings including significant elevations of creatine kinase during the neonatal period which declined rapidly within the first few months of life. The mean age of first recognition of abnormal brain white matter appearance on MRI was 12.0 months. The first report of failure to thrive was at a mean age of 23.4 months. Noninvasive ventilation was initiated in half the patients by 24 months of age. This data represents the largest multinational retrospective early natural history study of LAMA2-RD which provides data essential for understanding early clinical history, especially as international, prospective early natural history data collection is in progress. Promising therapies in preclinical development for LAMA2-RD may ameliorate the phenotype of LAMA2-RD, particularly when initiated early in the course of the disease, making the comprehensive understanding of early natural history of LAMA2-RD timely and of great importance.

The Educational Relations and Agrarian Life Orientation in the Majapahit Period

The Majapahit Kingdom is one of the major Hindu-Buddha kingdoms in the Nusantara. The kingdom that has been around for a long time certainly has a lot of history that deserves to be studied, such as the education system, and the system of economic life. Both certainly have an inseparable relationship, between education and the agrarian system of life. The purpose of this study was to determine the relationship between non-formal education and agrarian life in the Majapahit kingdom, both in terms of the economic system and knowledge of the people at that time in their agrarian life, besides that the purpose of this study was to educate readers about informal education. During the Majapahit era and its relationship with the orientation of the agrarian life of the Majapahit kingdom, this discussion is expected to further broaden the reader's insight into the history of the Nusantara. This study uses qualitative methods and historical data collection in order to describe an event, social activity, thought, belief either individually or in groups. As for the results obtained from this study, the Majapahit kingdom was an agrarian kingdom, where the economic sector was in the agricultural sector. The technology used in agriculture has existed since ancient times, but it is still simple. Based on the discussion with this method, we come to a conclusion that, Majapahit was a very developed kingdom in its time, both in terms of education and agrarian life and the relationship between the two was very closely related.

Swiss human geographies lecture 2019 tourism troubles: feminist political ecologies of land and body in Panama

Abstract. On the Panamanian Caribbean coast and the Bocas del Toro Archipelago, foreign direct investment via residential tourism development drives land displacement. As land insecurities grow, particularly for local Indigenous and Afro-Panamanian peoples, ongoing dispossession is not simply about land, but rather simultaneously about land, people and their bodies. In Bocas, foreign land enclosures are infused with imaginaries, which take for granted Black female servitude and Black landlessness. Such imaginaries seemingly lock economically “poor” Afro-Panamanian women into particular kinds of work. To illustrate, I entangle feminist political ecological assertions that struggles over nature are embodied struggles, with intersectional and relational understandings of land and body. To do so, I draw insights from postcolonial, decolonial and Black feminist critiques of coloniality and settler colonialism. Building from this literature, I seek to show how a logic of elimination operates within the legal geographies of residential tourism development. In doing so, I highlight the historical and contemporary ways in which Afro-Panamanian women are naturalized as criadas (maids), a process that accompanies land enclosure. Blending ethnographic and historical data collection, I seek to illuminate how Afro-Panamanian women's livelihood struggles reflect both their acquiescence to residential tourism development, and their resilience in the face of Bocas' anti-black patriarchal coloniality. Thus, I argue that Afro-Panamanian women's desires for inclusion and belonging in Bocas' tourism enclave – a project that seeks to eliminate Indigenous and Black relations to coastal lands and foster their embodied subjection to foreign nationals – simultaneously reflects their struggles for the right to remain on the coast.