Leeches (Phylum: Annelida, Class: Hirudinea) are widely distributed all over the world in diverse habitats, such as freshwater, seas, deserts, and oases (Gouda 2006). They can be predators, vectors of parasites, or even prey of other aquatic animals (Saywer 1986a; Keim 1993). In recent years, the population of leeches have declined dramatically due to over-exploitation for fishing bait and medicinal purposes (particularly in Europe and Asia), and due to pollution (Sawyer, 1981; Elliot & Tullett 1984; Wells & Coombes 1987; Petrauskiene 2003; Trontelj & Utevsky 2005). Leech therapy is one of the most important and widely practiced methods of regimental therapy used for local evacuation of morbid tumors (Ibn Sina 1998). The therapy is known from the time of extreme antiquity, more than 2,500 years ago and is still being practiced until now. This fact testifies to its efficiency in various health problems. In Malaysia, the entrepreneurs use leeches as trading animal and they are exported to meet the demand in countries such as Korea, Ukraine, China and Spain. Normally, the products are exported in the dried form approved and certified by the Department of Fisheries, Ministry of Agriculture and Agro Based Industry, Malaysia. However, there are also a handful of unscrupulous entrepreneurs who used leeches for personal gain by deceiving the public in traditional medicine. This action on their part can harm the farming industry and cause hesitation amongst the local folks on the viability of the industry for new entrepreneurs who want to venture in this field.Leeches have been used for centuries in the treatment of variety of diseases, including thromboembolic disorders and inflammatory states. With the advent of modern medicine, leeching is slowly demising, yet interest in the medicinal use of the are still demanding. Leeches have been used successfully to restore the flow of blood in microcirculation after plastic surgery (Mutimer et al. 1987).Local Leech Status and IssueLeeches is a sanguivorous (haemopagic), freshwater leech, with a wide distribution in Southeast Asia such as in southern China, the Philippines, Thailand, Vietnam, and Malaysia. In Malaysia, these leeches are known as 'Lintah Kerbau' (406th Medical Lab. Special Repor, 1968). There has been numerous collection of this species for medical purposes in the 20th century (Steiner et al. 1990; Electricwala et al. 1993; Singhal & Davies 1996). The Department of Wildlife Protection and National Parks (PERHILITAN) previously operated the industry in Malaysia. Since 22nd of January 2009, the Department of Fisheries Malaysia has taken over the operation of local leech's industry (Department of Fisheries Malaysia 2009). The Fisheries Department have since identified the species that can be used for commercial purposes. The taxonomic status of the local is as follows: Order: Hirudinea; Species: Hirudinaria manillensis; Local name: Buffalo or lintah kerbau (Figure 1 ).However, it is not known or proven conclusively that the locally named Buffalo Leech is not of H. manillensis although this has been confirmed by Department of Fisheries Malaysia. In addition, local taxonomists have not been able to identify the species used for medicinal purposes (Rosly Hassan April 2, 2010).In Malaysia, there are two types of different local species namely brown buffalo leech and buffalo leech (Figure 2 and 3) (Zulhisyam A.K. et al. 2014). Previously, the folks used a green buffalo for medical purposes especially for cupping treatment. Nevertheless, there are also entrepreneurs that used a dark brown local for medical purposes without knowing the basic protein function between the species. However, in Malaysia researches on gathering more information of the hirudin protein is still far and between.Cupping from the Islamic PerspectiveLeech therapy is one of the most important and widely practiced methods of regimental therapy used for local evacuation of morbid tumors (Ibn Sina 1998). …