Two field experiments were conducted in the Central Rift Valley of Ethiopia in the hot and cool dry seasons of 2016/2017 with the objective to develop an insecticide resistance management program on thrips infesting onion. The first experiment dealt with the evaluation of four different insecticides namely profenofos, λ–cyhalothrin, imidacloprid, and spinetoram in different sequences on thrips population and their effect on yield. The second experiment examined the effect of admixing the surfactant organosilicone with imidacloprid, spinetoram and dimethoate. A Randomized Complete Block Design with three replications was used for both experiments. Data on number of thrips, bulb yield and economic returns were collected. The insecticide imidacloprid and spinetoram resulted in fewer numbers of thrips and higher yields than profenofos and λ –cyhalothrin. Application of the more effective insecticides when the thrips population was high followed by less effective insecticides resulted in better control and higher economic return. Surfactant added insecticides gave a fewer numbers of thrips and higher yields than the corresponding insecticides applied without surfactant. The sequential application of spinetoram and imidacloprid with less effective λ-cyhalothrin and profenofos by mixing with adjuvant are recommended for thrips control as an integral component of thrips management in the Central Rift Valley of Ethiopia.