As the operating density of China’s high-speed railway increases, the phenomenon of interlayer debonding in movable point crossing (MPC) is becoming more prevalent, which can lead to failure of the frog’s slab track. Meanwhile, vehicle impacts and interlayer debonding can exacerbate abnormal vibration of the vehicle and even lead to derailment. Therefore, based on the theory of rigid-flexible coupling dynamics, a vehicle-turnout-slab coupling dynamics model is established for the first time. In this model, the crossing rails with variable cross sections is considered and the interlayer debonding between turnout slabs is modelled by nonlinear springs. Then, the characteristics of the debonding is identified by applying a wavelet transform to the dynamic response of the vehicle. Finally, different types and sizes of debonding between the layers are considered. The results show that different debonding can lead to two types of contact, partial contact and complete voiding, which can further lead to detrimental effects on vehicle safety. And the limit of the defect size that causes the track slab to void is 1 mm. On this basis, it was found that when MPC’s slab tracks were voided, longer debonding can cause high frequency vibration acceleration of approximately 700 Hz in the vehicle axle box. The new insights obtained by this study could provide guidance for the maintenance period and avoid the development of the damage. This study not only obtained a mechanism for the effect of interlayer debonding on the dynamic response of the vehicle-track system, but also provides a theoretical basis of detecting interlayer debonding for future study.