Microlubrication minimizes the exposure of metal working fluids to the machining operators leading to an economical, safer, and healthier workplace environment. In this study, a vegetable oil-based lubricant was used to conduct wear analysis and to analyze the effectiveness of microlubrication during end milling AISI 1018 steel. A solid carbide cutting tool with bright oxide finish was used with varying cutting speed and feed rate having a constant depth of cut. Abrasion was the dominant wear mechanism for all the cutting tools under consideration. Other than abrasion, sliding adhesive wear of the workpiece materials was also observed. The scanning electron microscope investigation of the used cutting tools revealed microfatigue cracks, welded microchips, and unusual built-up edges on the cutting tools flank and rake side. A full factorial experiment was conducted and regression models were generated for both the sides of tool flank wear. The study shows that with a proper selection of the cutting parameters it is possible to obtain higher tool life.