High-level Cognitive Functions Research Articles

Listening Effort Measured Using a Dual-task Paradigm in Adults With Different Amounts of Noise Exposure.

Excessive noise levels can result in hearing damage and/or hearing-related symptoms, thereby leading to impaired communication and, eventually a decrease in the quality of life. Moreover, in daily practice, subjects often indicate that listening in noisy situations is a challenging and often exhausting experience, even in the absence of a clinically significant hearing loss. Hence, a person's perceived difficulty of the listening situation will also be important to consider. It has been suggested that beyond the peripheral factors, there are some central cognitive correlates of speech understanding that are essential for communication abilities. The aim of the present study was to evaluate the effect of the amount of noise exposure on hearing as measured by pure-tone audiometry and otoacoustic emissions (OAEs) on the one hand and listening effort measured using a dual-task paradigm on the other hand. The study included 152 adults between 18 and 40 years of age. First, participants completed a self-administered questionnaire regarding the amount of noise exposure. Second, hearing status was evaluated using pure-tone audiometry and transient evoked OAEs (TEOAEs) as well as distortion product OAEs (DPOAEs). Finally, listening effort was evaluated using a dual-task paradigm, which consisted of a primary speech-recognition task in different listening conditions and a secondary visual memory task that were performed both separately and simultaneously. Based on the quartiles of their subjective estimation of noise exposure, the participants were categorized into a group with low noise exposure (lower quartile), moderate noise exposure (two middle quartiles), and high noise exposure (upper quartile). There was no significant difference in hearing thresholds between the participants with low, moderate, and high noise exposure for each frequency of the pure-tone audiometry. In contrast, more absent TEOAEs and DPOAEs were found in the high noise exposed group. Regarding the primary speech-recognition task of the dual-task paradigm, no significant difference in speech recognition was found between the different groups of noise exposure. For the amount of listening effort, it was found that across all listening conditions subjects with high noise exposure expend significantly more listening effort compared with subjects with low and moderate noise exposure. This study is a first exploration of the effects of different amounts of noise exposure on listening effort showing that, listening effort is increased in subjects with high noise exposure compared with subjects with low and medium noise exposure. The most plausible hypothesis pertains to an effect of noise exposure on the peripheral and central auditory system, or a combination of effects on both the auditory system and the high-level cognitive functions necessary for speech understanding in the subjects with high levels of noise exposure. As such, a test for listening effort would be useful as part of a comprehensive test battery within the assessment of subjects exposed to noise.

Post-Stroke Cognitive Impairment: Pathophysiological Insights into Brain Disconnectome from Advanced Neuroimaging Analysis Techniques.

The neurological symptoms of stroke have traditionally provided the foundation for functional mapping of the brain. However, there are many unresolved aspects in our understanding of cerebral activity, especially regarding high-level cognitive functions. This review provides a comprehensive look at the pathophysiology of post-stroke cognitive impairment in light of recent findings from advanced imaging techniques. Combining network neuroscience and clinical neurology, our research focuses on how changes in brain networks correlate with post-stroke cognitive prognosis. More specifically, we first discuss the general consequences of stroke lesions due to damage of canonical resting-state large-scale networks or changes in the composition of the entire brain. We also review emerging methods, such as lesion-network mapping and gradient analysis, used to study the aforementioned events caused by stroke lesions. Lastly, we examine other patient vulnerabilities, such as superimposed amyloid pathology and blood-brain barrier leakage, which potentially lead to different outcomes for the brain network compositions even in the presence of similar stroke lesions. This knowledge will allow a better understanding of the pathophysiology of post-stroke cognitive impairment and provide a theoretical basis for the development of new treatments, such as neuromodulation.

Structuring cooperative learning methods in Ancient Greek classrooms

AbstractConsidering the concept of critical teaching, teachers should seek to ensure the active participation of students, emphasisng the adoption of student-centred and group-centred teaching methods, which will provide students with relevant motivation for learning. From this perspective the current article focuses on a teaching proposal for the course of Ancient Greek Language in Greece and Cyprus, presenting the method of jigsaw-based cooperative learning as a teaching practice which promotes both active student participation and group cooperation. According to this teaching practice, the teacher actively involves the students in the learning process, promoting higher-level cognitive, metacognitive and emotional functions. Not only is this method compatible with the broader contemporary pedagogical and didactic principles, which aim to provoke students' interest, cultivate their social skills and relationships, develop their personal self-perception, and create autonomous and fulfilled personalities, but also it is harmonised with the main aims of the Ancient Greek Language Curriculum in these countries, which are fully aligned with both their education policy and their societal needs.

Occupational Depression, Cognitive Performance, and Task Appreciation: A Study Based on Raven’s Advanced Progressive Matrices

The Occupational Depression Inventory (ODI) was recently developed to assess depressive symptoms that individuals specifically attribute to their work. Research on the criterion validity of the instrument is still in its infancy. In this study, we examined whether the ODI predicted performance on, and appreciation of, a cognitively challenging test. In light of the link established between clinical depression and neuropsychological impairment, and considering that individuals with depressive symptoms are more likely to feel helpless under challenging circumstances, we hypothesized that occupational depression would be associated with poorer cognitive performance and a darkened appreciation of the task undertaken. We relied on a sample of 1,359 educational staff members. We used an abridged version of Raven’s Advanced Progressive Matrices (RAPMs) as a cognitively challenging task and measure of cognitive performance. RAPMs assess so-called eductive ability (meaning-making and problem-solving abilities) through items of various degrees of difficulty. Transient mood was assessed with a three-item measure before RAPMs were administered. Task appreciation was assessed with a single-item measure after the completion of RAPMs. We found occupational depression to be negatively linked to cognitive performance. A two-step cluster analysis, in which ODI and RAPMs scores were used as classifiers, revealed two profiles of respondents. The first profile was characterized by relatively low levels of depressive symptoms and high levels of cognitive performance; the second profile, by relatively high levels of depressive symptoms and low levels of cognitive performance. The two profiles differed strongly from one another, as indexed by Cohen’s ds of 2.492 regarding depressive symptoms and 1.263 regarding cognitive performance. As anticipated, occupational depression predicted a darkened appreciation of the test. The association remained statistically significant, and largely unchanged, controlling for pretest mood and test performance. The highest levels of depressive symptoms were observed among individuals evaluating the task as “frustrating” and “discouraging.” Our study suggests that occupational depression predicts poorer cognitive performance and a negativized experience of cognitive challenge. Such features may be part of a self-sustaining loop fostering the maintenance of depressive symptoms. The extent to which the ODI predicts performance in the work context needs to be investigated.

Cognitive reserve as a moderator of outcomes in five clusters of first episode psychosis patients: a 10-year follow-up study of the PAFIP cohort.

Cognitive reserve (CR) has been associated with the development and prognosis of psychosis. Different proxies have been used to estimate CR among individuals. A composite score of these proxies could elucidate the role of CR at illness onset on the variability of clinical and neurocognitive outcomes. Premorbid intelligence quotient (IQ), years of education and premorbid adjustment were explored as proxies of CR in a large sample (N = 424) of first-episode psychosis (FEP) non-affective patients. Clusters of patients were identified and compared based on premorbid, clinical and neurocognitive variables at baseline. Additionally, the clusters were compared at 3-year (N = 362) and 10-year (N = 150) follow-ups. The FEP patients were grouped into five CR clusters: C1 (low premorbid IQ, low education and poor premorbid) 14%; C2 (low premorbid IQ, low education and good premorbid adjustment) 29%; C3 (normal premorbid IQ, low education and poor premorbid adjustment) 17%; C4 (normal premorbid IQ, medium education and good premorbid adjustment) 25%; and C5 (normal premorbid IQ, higher education and good premorbid adjustment) 15%. In general, positive and negative symptoms were more severe in the FEP patients with the lowest CR at baseline and follow-up assessments, while those with high CR presented and maintained higher levels of cognitive functioning. CR could be considered a key factor at illness onset and a moderator of outcomes in FEP patients. A high CR could function as a protective factor against cognitive impairment and severe symptomatology. Clinical interventions focused on increasing CR and documenting long-term benefits are interesting and desirable.

Increased Functional Connectivity of the Intraparietal Sulcus Underlies the Attenuation of Numerosity Estimations for Self-Generated Words.

Previous studies have shown that self-generated stimuli in auditory, visual, and somatosensory domains are attenuated, producing decreased behavioral and neural responses compared with the same stimuli that are externally generated. Yet, whether such attenuation also occurs for higher-level cognitive functions beyond sensorimotor processing remains unknown. In this study, we assessed whether cognitive functions such as numerosity estimations are subject to attenuation in 56 healthy participants (32 women). We designed a task allowing the controlled comparison of numerosity estimations for self-generated (active condition) and externally generated (passive condition) words. Our behavioral results showed a larger underestimation of self-generated compared with externally generated words, suggesting that numerosity estimations for self-generated words are attenuated. Moreover, the linear relationship between the reported and actual number of words was stronger for self-generated words, although the ability to track errors about numerosity estimations was similar across conditions. Neuroimaging results revealed that numerosity underestimation involved increased functional connectivity between the right intraparietal sulcus and an extended network (bilateral supplementary motor area, left inferior parietal lobule, and left superior temporal gyrus) when estimating the number of self-generated versus externally generated words. We interpret our results in light of two models of attenuation and discuss their perceptual versus cognitive origins.SIGNIFICANCE STATEMENT We perceive sensory events as less intense when they are self-generated compared with when they are externally generated. This phenomenon, called attenuation, enables us to distinguish sensory events from self and external origins. Here, we designed a novel fMRI paradigm to assess whether cognitive processes such as numerosity estimations are also subject to attenuation. When asking participants to estimate the number of words they had generated or passively heard, we found bigger underestimation in the former case, providing behavioral evidence of attenuation. Attenuation was associated with increased functional connectivity of the intraparietal sulcus, a region involved in numerosity processing. Together, our results indicate that the attenuation of self-generated stimuli is not limited to sensory consequences but is also impact cognitive processes such as numerosity estimations.

Hierarchical modelling of functional brain networks in population and individuals from big fMRI data

A major goal of large-scale brain imaging datasets is to provide resources for investigating heterogeneous populations. Characterisation of functional brain networks for individual subjects from these datasets will have an enormous potential for prediction of cognitive or clinical traits. We propose for the first time a technique, Stochastic Probabilistic Functional Modes (sPROFUMO), that is scalable to UK Biobank (UKB) with expected 100,000 participants, and hierarchically estimates functional brain networks in individuals and the population, while allowing for bidirectional flow of information between the two. Using simulations, we show the model's utility, especially in scenarios that involve significant cross-subject variability, or require delineation of fine-grained differences between the networks. Subsequently, by applying the model to resting-state fMRI from 4999 UKB subjects, we mapped resting state networks (RSNs) in single subjects with greater detail than has been possible previously in UKB (>100 RSNs), and demonstrate that these RSNs can predict a range of sensorimotor and higher-level cognitive functions. Furthermore, we demonstrate several advantages of the model over independent component analysis combined with dual-regression (ICA-DR), particularly with respect to the estimation of the spatial configuration of the RSNs and the predictive power for cognitive traits. The proposed model and results can open a new door for future investigations into individualised profiles of brain function from big data.

Functional Connectivity Within the Fronto-Parietal Network Predicts Complex Task Performance: A fNIRS Study.

Performance in complex tasks is essential for many high risk operators. The achievement of such tasks is supported by high-level cognitive functions arguably involving functional activity and connectivity in a large ensemble of brain areas that form the fronto-parietal network. Here we aimed at determining whether the functional connectivity at rest within this network could predict performance in a complex task: the Space Fortress video game. Functional Near Infrared Spectroscopy (fNIRS) data from 32 participants were recorded during a Resting-State period, the completion of a simple version of Space Fortress (monotask) and the original version (multitask). The intrinsic functional connectivity within the fronto-parietal network (i.e., during the Resting-State) was a significant predictor of performance at Space Fortress multitask but not at its monotask version. The same pattern was observed for the functional connectivity during the task. Our overall results suggest that Resting-State functional connectivity within the fronto-parietal network could be used as an intrinsic brain marker for performance prediction of a complex task achievement, but not for simple task performance.

Olfactory Stimulation Modulates Visual Perception Without Training.

Considerable research shows that olfactory stimulations affect other modalities in high-level cognitive functions such as emotion. However, little known fact is that olfaction modulates low-level perception of other sensory modalities. Although some studies showed that olfaction had influenced on the other low-level perception, all of them required specific experiences like perceptual training. To test the possibility that olfaction modulates low-level perception without training, we conducted a series of psychophysical and neuroimaging experiments. From the results of a visual task in which participants reported the speed of moving dots, we found that participants perceived the slower motions with a lemon smell and the faster motions with a vanilla smell, without any specific training. In functional magnetic resonance imaging (fMRI) studies, brain activities in the visual cortices [V1 and human middle temporal area (hMT)] changed based on the type of olfactory stimulation. Our findings provide us with the first direct evidence that olfaction modulates low-level visual perception without training, thereby indicating that olfactory-visual effect is not an acquired behavior but an innate behavior. The present results show us with a new crossmodal effect between olfaction and vision, and bring a unique opportunity to reconsider some fundamental roles of olfactory function.

Thalamo-cortical spiking model of incremental learning combining perception, context and NREM-sleep.

The brain exhibits capabilities of fast incremental learning from few noisy examples, as well as the ability to associate similar memories in autonomously-created categories and to combine contextual hints with sensory perceptions. Together with sleep, these mechanisms are thought to be key components of many high-level cognitive functions. Yet, little is known about the underlying processes and the specific roles of different brain states. In this work, we exploited the combination of context and perception in a thalamo-cortical model based on a soft winner-take-all circuit of excitatory and inhibitory spiking neurons. After calibrating this model to express awake and deep-sleep states with features comparable with biological measures, we demonstrate the model capability of fast incremental learning from few examples, its resilience when proposed with noisy perceptions and contextual signals, and an improvement in visual classification after sleep due to induced synaptic homeostasis and association of similar memories.

Working Memory Load Effects on the Tilt Aftereffect.

Prolonged exposure to an oriented stimulus causes a subsequent test stimulus to be perceived as tilted in the opposite direction, a phenomenon referred to as the tilt aftereffect (TAE). Previous studies have demonstrated that high-level cognitive functions such as attention can modulate the TAE, which is generally well-known as a low-level perceptual process. However, it is unclear whether working memory load, another high-level cognitive function, could modulate the TAE. To address this issue, here we developed a new paradigm by combining a working memory load task with a TAE task. Participants firstly remembered a stream of digits (Experiment 1) or four color-shape conjunctions (Experiment 2) under high/low load conditions, and then recognized the probe stimuli (digits or a color-shape conjunction), which were presented at the center of an adapting grating. After the recognition task (i.e., the adaptation stage), participants performed an orientation judgment task to measure their TAEs. The result of Experiment 1, where the load stimuli were digits, showed that the magnitude of the TAEs were reduced under the condition of the high working memory load compared to that of the low working memory load. However, we failed to replicate the finding in Experiment 2, where the load stimuli were color-shape conjunctions. Together, our two experiments provided mixed evidence regarding the working memory load effects on the TAE and further replications are needed in future work.

Movement-Related Gamma Synchrony Differentially Predicts Behavior in the Presence of Visual Interference Across the Lifespan.

The ability to allocate neural resources to task-relevant stimuli, while inhibiting distracting information in the surrounding environment (i.e., selective attention) is critical for high-level cognitive function, and declines in this ability have been linked to functional deficits in later life. Studies of age-related declines in selective attention have focused on frontal circuitry, with almost no work evaluating the contribution of motor cortical dynamics to successful task performance. Herein, we examined 69 healthy adults (23-72years old) who completed a flanker task during magnetoencephalography (MEG). MEG data were imaged in the time-frequency domain using a beamformer to evaluate the contribution of motor cortical dynamics to age-related increases in behavioral interference effects. Our results showed that gamma oscillations in the contralateral motor cortex (M1) were a robust predictor of reaction time, regardless of interference level. Additionally, we observed condition-wise differences in gamma-by-age interactions, such that in younger adults, increases in M1 gamma power were predictive of faster reaction times during incongruent trials, while older adults did not receive this same behavioral benefit. Importantly, these data indicate that M1 gamma oscillations are differentially predictive of behavior in the presence, but not absence of visual interference, resulting in exhausted compensatory strategies with age.

Results of revascularizing operations performed in the acute period of subarachnoid hemorrhage

The study objective is an assessment of long-term results of cerebral revascularization performed in the acute period of subarachnoid hemorrhage due to rupture of cerebral aneurysms.Materials and methods. This cross-sectional study includes 74 patients, operated in N.V. Sklifosovsky Research Institute for Emergency Medicine in the acute period of aneurysmal subarachnoid hemorrhage. Patients were divided into two groups. The first group contained patients with EC—IC bypass performed in the acute period of aneurysmal subarachnoid hemorrhage. The Control group contained patients without bypass. In the long-term period, 11 patients were examined. Computed tomography of cerebral vessels, duplex ultrasound examination of the aortic arch, brachiocephalic arteries and intracranial vessels, transcranial Doppler ultrasonography with a breathing function test, single-photon emission computed tomography of the brain followed by stress test with acetazolamide, Modified Renkin Scale, Mini-Mental State Examination, Montreal Cognitive Assessment, Index Bartel, The Hospital Anxiety and Depression Scale, Holms-Rahe were performed. For descriptive results, a mathematical model was used.Results. The best treatment outcomes in severe patients with subarachnoid hemorrhage and cerebral ischemia were observed when performing simultaneous clipping of the aneurysm and EC-IC bypass (57.1 % versus 41.0 %) there was no statistically significant difference in outcomes. EC-IC bypass functioned in 37.5 % of cases. The rate and acceleration of the fall in volumetric blood flow and the passage of blood from the aortic bulb to the cerebral arterioles affect the perfusion values in the region of the brain concerned. Evaluation of long-term results of simultaneous interventions revealed persistent disturbances in the regulation of cerebral blood flow at the microcirculatory level. Patients with EC-IC bypass had a higher level of cognitive function and stress potential.Conclusion. The results of this study showed us the necessity for a comprehensive exploration of cerebral blood flow.

Advance Directive Completion Among Older American Couples: A Dyadic Perspective on the Role of Cognitive Function and Other Factors.

Dyadic perspective is scarce in existing advance directive (AD) literature. Particularly, the significance of one's own and/or one's partner's cognitive function on AD remains unknown. This study investigates the relationship of cognitive function and other factors with AD completion within the spousal context. Data from the Health and Retirement Study (2014-2015) were used. Older heterosexual couples (age ≥65) married for 10+ years were asked if they had a living will and/or appointed a durable power of attorney for health care (DPAHC). Structural equation models examined the actor and partner effects of sociodemographic, health, and couple-level characteristics on wife's and husband's AD, respectively. Moderate spousal interdependence was observed in living will (kappa coefficient, κ = .60) and DPAHC (κ = .53). Older age and higher education were related to both spouses having AD. Less household wealth and being racial/ethnic minority were associated with a lower probability of having AD. Notable gender contrasts in actor and partner effects were found. Wife's higher level of cognitive function was associated with husband's AD completion. Contrarily, husband's lower level of cognitive function was associated with wife's AD completion. Retirement status had primarily actor effects for both husbands and wives. More chronic conditions were linked to husband's AD completion. The spousal interdependence of AD warrants practitioner efforts to facilitate family-oriented end-of-life planning. Wives and husbands may have different thoughts regarding their spouse's cognitive capacity to surrogate. Facilitating couple-based discussions may be a feasible approach to promote engagement with AD among older adults.

Neighborhood active aging infrastructure and cognitive function: A mixed-methods study of older Americans

Physical exercise benefits cognitive functioning and can protect against neurodegeneration. Neighborhood environments may be pivotal to physically active aging, and thus help shape older adults' cognitive function. This mixed-methods study investigated where older adults exercised outside the home, and whether availability of these neighborhood sites was associated with cognitive function. We thematically analyzed qualitative data from semi-structured interviews in 2015 with 125 older adults (mean age = 71) in the Minneapolis (MN) metropolitan area. Results identified nearby public parks, fitness/sports amenities, and walkable destinations as motivators for recreational exercise and active transit among participants. These findings informed quantitative analysis of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, a national sample of older Black and white Americans (n = 21,151; mean age at assessment = 67; data collected 2006–2017). We used generalized additive multilevel models to examine whether neighborhood features that qualitative participants identified as encouraging physical activity were associated with elevated levels of cognitive function. Results indicated that residing in neighborhoods with greater availability of local parks, access to recreational amenities, and business density was associated with higher levels of cognitive function. We found no evidence to suggest a significant association between availability of these neighborhood resources and rate of cognitive decline. This study identifies specific neighborhood active aging infrastructure that may support cognitive function among older adults aging in place.

The Impact of Auditory White Noise on Cognitive Performance

Although noise has often been characterized as a distractor, contemporary studies have emphasized how some individuals’ cognitive performance could benefit from task-irrelevant noise. Usually these studies focus on sub-attentive individuals and/or those who have been diagnosed with ADHD. An example of task-irrelevant noise is white noise (WN). Research regarding the effectiveness of WN in healthy adults has provided mixed results and therefore, the implications of WN remain unknown. The objective of this study was to determine the effects of WN on the cognitive performance of the neurotypical population. To test this, participants were asked to complete simultaneous amplitude discrimination and temporal order judgement (TOJ) tests several times in the presence of varying levels of WN. Participants were split into two groups––one containing individuals with regular prior WN exposure and the other with no previous experience with WN. The performances of participants with prior exposure to WN, but not those without prior exposure, resembled a U-shaped tuning curve for simultaneous amplitude discrimination. This indicates that familiarity with WN moderates its effectiveness on cognitive improvement. TOJ was not found to be affected by varying levels of WN intensity. The results of this study emphasized that there is a possibility that WN could facilitate higher levels of cognitive performance, though there is likely an adjustment period associated with its introduction to daily life. This warrants that additional research should be conducted in order to cultivate a definitive conclusion about the effects of WN.

Occupational performance issues in older adults with subjective cognitive decline

Purpose To describe and categorize difficulties in daily activities of older adults with subjective cognitive decline (SCD) compared to individuals with mild cognitive impairment (MCI). Methods Deductive quantitative content analysis was used to classify reported issues in the performance of meaningful daily activities, in older adults with SCD (n = 67; age= 70 ± 6.3) or MCI (n = 42; age= 72 ± 6.6). The occupational performance issues were identified using the Canadian Occupational Performance Measure, a semi-structured interview, and categorised using the International Classification of Functioning, Disability and Health (ICF). Results Both groups identified issues in all nine ICF “Activities and Participation” domains, with no significant group effects on seven of them. The most frequently affected “Activities and Participation” domains in both groups were “Self-care” (e.g. exercise and diet); “Community, social and civic life” (e.g. social-leisure activities); and "General tasks and demands” (e.g. time management). Over 90% of the issues in both groups were described in the context of difficulties in “Mental functions” (e.g. memory and higher-level cognitive functions). Conclusions Older adults with SCD, although independent, identified a variety of daily activities that they are not performing satisfactorily, remarkably similar in nature to the occupational performance issues described by older adults with MCI. Implications for Rehabilitation Older adults with SCD identified difficulties in performing social and leisure activities, maintaining healthy lifestyle behaviours, and managing multiple daily tasks. The daily challenges described by older adults with SCD are similar in nature to those identified by those with MCI. Older adults with SCD and MCI describe their daily challenges are related not only to memory problems, but also to executive dysfunction. Interventions for older adults with SCD should aim to improve self-identified problems in everyday functioning.

Social Networks in an Assisted Living Community: Correlates of Acquaintance and Companionship Ties Among Residents.

ObjectivesSocial relationships are important for older adults’ well-being, including those who live in assisted living (AL) communities. This study explores coresident networks within an AL community and identifies factors associated with residents’ social ties.MethodsAcquaintance and companionship networks within the community are described using cross-sectional survey data (N = 38). We use inferential network statistical methods to estimate parameters for factors associated with residents’ acquaintance and companionship ties.ResultsResidents reported an average of 10 acquaintances and almost 4 companionships with other residents in the sample. The likelihood a resident had an acquaintance was associated with higher levels of cognitive functioning (p < .05), higher levels of physical limitations (p < .01), living in the AL community for a longer time (p < .01), and less frequent contact with outside family and friends (p < .05). Acquaintances were more likely between residents who moved in around the same time as each other (p < .01), lived on the same floor (p < .001), or had similar levels of physical limitations (p < .05). Companionships were more likely to be reported by male residents (p < .05) and residents with higher levels of cognitive functioning (p < .05) or depressive symptoms (p < .05). Longtime residents were more popular as companions (p < .01). Companionships were more likely between residents who lived on the same floor (p < .001) or were similar in age (p < .01).DiscussionThis research contributes to the literature of older adults’ nonkin social relationships by providing detailed descriptions of the acquaintance and companionship networks within an AL community, quantifying correlates of residents’ social ties, and distinguishing between acquaintances and companions.

I know what I saw

Evolutionary Cognition Over the past several decades, evidence has accumulated showing that some nonhuman animals have conscious awareness. Some argue that despite high-level cognitive function, this may be occurring without conscious awareness of self. Unfortunately, we cannot ask animals to report their experiences. Ben-Haim et al. exploited the human faculty for crossover double dissociation between nonconscious and conscious processing and applied it to rhesus macaques. People perform in completely opposite ways when they are aware of stimuli compared with when they are not. In the authors' visual tests, the macaques showed nearly identical responses to those of humans, indicating that the monkeys reacted differently when they were consciously aware that they had seen a stimulus compared with when they were not. Proc. Natl. Acad. Sci. U. S. A. 118 , e2017543118 (2021).

Relationship between mindfulness, stress, and performance in medical students in pediatric emergency simulations.

Objectives: Pediatric teams of emergency departments work under extreme stress, which affects high-level cognitive functions, specifically attention and memory. Therefore, the methods of stress management are being sought. Mindfulness as a process of intentionally paying attention to each moment with acceptance of each experience without judgment can potentially contribute to improving the performance of medical teams. Medical simulation is a technique that creates a situation to allow persons to experience a representation of a real event for the purpose of education. It has been shown that emergency medicine simulation may create a high physiological fidelity environment similarly to what is observed in a real emergency room. The aim of our study was to determine whether the technical and non-technical skills of medical students in the course of pediatric high fidelity simulations are related to their mindfulness and stress. Participants and methods: A total of 166 standardized simulations were conducted among students of medicine in three simulation centers of medical universities, assessing: stress sensation (subjectively and heart rate/blood pressure), technical (checklists) and non-technical skills (Ottawa scale) and mindfulness (five facet mindfulness questionnaire): ClinicalTrials.gov ID: NCT03761355. Results: The perception of stress among students was lower and more motivating if they were more mindful. Mindfulness of students correlated positively with avoiding fixation error. In the consecutive simulations the leaders’ non-technical skills improved, although no change was noted in their technical skills. Conclusion: The results of our research indicate that mindfulness influence the non-technical skills and the perception of stress of medical students during pediatric emergency simulations. Further research is needed to show whether mindfulness training leads to improvement in this field.