High Incidence Of Positive Findings Research Articles

P-015 A New Grading System for Predicting Angiogram Negative Subarachnoid Haemorrhage

IntroductionAngiogram negative subarachnoid haemorrhage (AN-SAH) account for about 15% of all non-traumatic SAH cases. In this paper we developed a new CT based grading system for distinguishing AN-SAH vs. aneurysmal...

Prognostic and therapeutic implication of residual timorous tissue in cervix conizate

Conization is an excisive technique used for both diagnostic and therapeutic purposes. If conizate margines do not show any pathologic changes (negative findings) it is also the only therapeutic measure which should be applied. In case of conizate margins affected by the disease (positive findings), it is necessary not only to assess various parameters but also to decide on a further therapeutic approach. The aim of this study was to determine the incidence of positive findings and its impact on a further optimal therapeutic approach choice. The data for analyses were retrospectively acquired through an insight into the medical records of the female patients who had undergone conization in the Institute for Gynecology and Obstetrics, Clinical Center of Serbia, within a period from 1995 to 2000. Histopathologic analyses of the bioptic and cervical conizate and reconizate samples were performed in the same institute. The acquired data were analyzed and statistically processed. Within the above mentioned period, a total of 823 conizations were done. In 76 patients, positive findings were determined. The acquired data analysis revealed positive findings decrease during this period, yet with no statistical significance. Higher statistically significant incidence of positive findings, however, was revealed in the patients over 40 years of age. Also, a statistically significantly higher incidence of positive findings was revealed in the apex as compared with other localizations. During the period observed, there was the raise of the number of patients only followed up after the conization without reconization. Also evident was decreasing in the number of histerectomies followed by increasing in the number of reconizations, as the method for reintervention. The most common cause of histerectomy was the apex positive findings with no statistical significance, while of reconization it was positive finding on lateral conizate margins with statistical significance. The association of the apical conizate positive finding with that in the curettements in all the cases was in correlation with positive findings at reintervention. According to the results obtained by analyzing and statistical processing of the acquired data, it could be concluded that reconization does represent a more suitable reintervention in patients with positive conizate findings as compared to histerectomy.

Is the posterior belly of the digastric muscle palpable? A qualitative systematic review of the literature

Palpation of the posterior belly of the digastric muscle in the postmandibular region is included in many study protocols and examination schemes of the masticatory system. The aim of the present investigation was to systematically search the dental/medical literature to find evidence for the palpability of this muscle. In August 2004, a systematic search was carried out using different electronic databases (PubMed, Cochrane Library, Web of Science, Japana Centra Revuo Medicina, MedPilot, Latin American and Caribbean Health Sciences, and three on-line databases of dental journals not listed currently in Medline), supplemented by manual search in the Austrian journal Stomatologie. Additional manual searches were carried out in the Journal of Orofacial Pain and Journal of Dental Research to identify pertinent abstracts of scientific congresses. One relevant hit was found in the Japanese database. The manual search showed one pertinent congress abstract. In both publications, the authors concluded that due to anatomical reasons the posterior belly of the digastric muscle was not palpable. Hence, evidence is lacking that the posterior digastric muscle is accessible to palpation. Because the postmandibular region is usually tender upon palpation, a high incidence of positive findings can be expected even among healthy subjects. This may lead to wrong clinical judgments, possibly provoking unnecessary diagnostic and therapeutic measures.

Panoramic radiographic examination of edentulous patients

A study of panoramic radiographs made on 114 edentulous patients was described. Six radiographic entities were identified: (1) root fragments, (2) retained teeth, (3) radiolucencies, (4) radiopacities, (5) foreign bodies, and (6) mental foramina at or near the crest of the residual ridge. The percent of positive findings in this study and those of previous studies support the fact that one of three edentulous patients has a potentially complicating condition within the denture base foundation. These investigations stress the necessity of radiographic examination of all edentulous patients prior to treatment with complete dentures. The high incidence of positive findings suggests not only the need for radiographic examinations of all patients, but also the frequency with which the dentist is faced with the necessity of modifying the treatment plan.

Sperm antibody testing in infertile men.

Six hundred male patients were examined for circulating spermagglutinating antibodies by the Kibrick sperm-agglutination test and 20% demonstrated autoantibodies. The high incidence of positive findings may be explained by the select population studied. Of 80 men tested who demonstrated more than 10% agglutination in their semen, but were otherwise normospermic, 41% demonstrated positive titers by the Kibrick method. Of 300 men examined for circulating sperm-immobilizing antibodies by the Isojima sperm-immobilizing test, 6% had autoantibodies. This high incidence of positive findings demonstrates the need for these tests in males who otherwise appear normospermic or demonstrate an unexplained infertility.

Epidemiologic aspects of viral hepatitis in Greece.

Studies of hepatitis-associated antigen (HAA) in viral hepatitis in Greece have shown a high incidence of positive findings not only in serum hepatitis, but also in cases classified as infectious because of the absence of a history of parenteral inoculation. 1-3 However, in most of these studies, no distinction between adults and children was made, and no cases of epidemic hepatitis were included. 2,3 We believe it of interest, therefore, to present briefly additional findings of ours on the incidence of HAA in three major epidemiological cateogries of viral hepatitis (serum, epidemic, and sporadic) and to compare the findings in adults with those in children. Material and Methods Two hundred twenty-nine patients with viral hepatitis were included; 132 were adults and 97 were children (under 14 years of age). Viral hepatitis was classified in three major epidemiological groups: (1) posttransfusion or syringe (50 cases), (2) sporadic without history of

Duodenal Ulcers in Children

Duodenal ulcers have been reported in children with increasing frequency (5–11) since Alexander (1) published his group of thirty cases in this journal in 1951, but few of these reports have appeared in the radiologic literature (2). In the same year Morgan (10) also published an excellent review, which thoroughly discussed this condition in children. Many of the more recent papers (3, 6, 12) have stressed the psychiatric factors in the background of these young patients and we have recognized in most of our cases a typical psychologic pattern or have discovered a strong stress situation as a precipitating factor in the production of ulcer. Since 1949 we have made the diagnosis of duodenal ulcer 15 times in children between two and fifteen years old, out of approximately 92 patients of this age group seen in our office for gastrointestinal studies. This high incidence of positive findings reflects, we feel, not so much a high incidence of disease in this age group as a very conservative attitude on the part of the physicians who refer patients to us for examination. The children must complain for a long time before they are sent for study, and we feel, therefore, that we are dealing with a selected group in which a high percentage of positive examinations may be expected. The etiology of duodenal ulcer in children, as in adults, is unknown. According to Alexander, “the factors of nervousness, worry, and strain and overindulgence in food, alcohol, or tobacco would seem to play little, if any, part in the production of ulcer in patients of this age.” The implication that children have no worries is at variance with our experience, although many of the things that trouble a child would, to an adult, be inconsequential. A good example of this type of worry and nervous strain is afforded by a four-year-old boy whom we saw in 1951. He had always been well until his parents went to Europe for three months, leaving him and his brother with an aunt. The boy stopped eating, started complaining of severe abdominal pain, and on our examination was found to have a large crater in the duodenal cap. This was treated medically, and after his parents' return his symptoms subsided completely. We saw this child in 1958, after seven years, and he had had no further stomach trouble. Morgan, after reviewing the various theories of the etiology of ulcer, held the neurogenic theory to be the most tenable. In infants with brain damage, disturbances of the autonomic nervous system controlling centers may cause vascular change in the stomach or duodenum sufficiently great to allow erosive lesions to form. In older children with a suppressed anxiety state continued over a period of time, similar vascular changes may be mediated through the autonomic nervous system, leaving the mucosa of the stomach and duodenum open to ulceration.

A comparison of the Hinton, Kahn, Kline, and Mazzini tests for syphilis

Abstract These results confirm the findings of Mazzini and Giordano as to the specificity and sensitivity of the Mazzini test. Since the Mazzini test is more sensitive than the Kline and Kahn diagnostic tests and the Hinton test, it gave a lower incidence of negative reactions and a higher incidence of positive findings. The Kline, Kahn, Hinton and Mazzini tests gave a relative agreement of approximately 95.26 per cent, and an absolute agreement of 93.93 per cent. In an additional series of 1,042 specimens from college students, the Kline and Mazzini tests gave a relative agreement of 99.8 per cent and a complete agreement of 99.51 per cent. The occurrence of nonspecific (false positive) reactions is mentioned. The occurrence of conflicting results of various tests in clinically diagnosed cases of syphilis is discussed. The results, in our opinion, justify the use of a multiple test system. In our opinion the Mazzini test is an excellent test for the laboratory diagnosis of syphilis.