High Coverage Research Articles

Optimizing air quality monitoring spatial layout by maximizing the coverage of the population in Beijing–Tianjin–Hebei and surrounding areas

The spatial layout of the air quality monitoring network (AQMN) is crucial for objective, accurate, and comprehensive air quality assessment. The current technical standard specified the minimum quantity requirements for air quality monitoring sites, but there were no standards to specify the spatial of monitoring sites. This study proposed a novel framework to evaluate and optimize the spatial layout of AQMN. First, this study proposed three indicators to evaluate the performance of the current AQMN. They were monitoring area repetition rate, population coverage rate, and correlations. The assessment of AQMN in Beijing–Tianjin–Hebei and surroundings areas (BTHs) showed the overall monitoring area repetition rate and population coverage rate was 81.07 % and 35.5 %, respectively, which means the current AQMN in BTHs has very high monitoring repeatability and limited population coverage. Secondly, a large-scale linear programming model was built to optimize the spatial layout and determine the spatial location of 279 newly added monitoring sites in BTHs according to the Environmental Monitoring 14th Five-Year Plan of China. The optimization results showed that the optimized AQMN covered 97 million additional people, and the population coverage rate increased to 49.5 %. The proposed framework provided a valuable tool to evaluate and optimize AQMN and could be a potential solution for developing new technical standards of AQMN.

Cs/O, Cs/NF3, and Cs/Li/NF3 coadsorption on GaAs0.5P0.5 (001) β2(2×4) reconstruction surface: A first principle study

The activation process of p-type doped GaAs0.5P0.5 (001) β2(2 × 4) reconstruction surface is investigated based on first principle calculations. For Cs-only adsorption, the adsorption energy rises as the Cs coverage increases, and when the Cs coverage is at 0.75 ML, the work function hits its minimum. Cs/O and Cs/NF3 concurrent adsorption are conducive to increasing steadiness and lowering the work function of the reconstruction surface during the phase of high Cs coverage. The work function reaches its minimum when Cs coverage is 0.75 ML in Cs/O coadsorbed models while that occurs when Cs coverage is 1.00 ML in Cs/NF3 coadsorbed models. Results indicate that the Li atoms intercalation with low coverage in Cs/NF3 coadsorbed models is conducive to establishing dipole moments, strengthening stability, and lowering the work function. The optimal adsorption recipe is 6Cs/2Li/NF3, with which the surface owns the lowest work function and shows the most stable property.

Intraday analyses on weather-induced sentiment and stock market behavior

We examine the intraday relationship between weather conditions and investor sentiment in the Korean equity market. By uncovering the intermediary role of weather-induced sentiment in affecting market variables, we suggest a potential link between weather conditions, sentiment, and market dynamics. High temperatures, humidity, and cloud coverage hurt investors’ moods, while strong winds and long sunshine durations have a positive impact. Though only cloud coverage marginally impacts stock returns, weather factors significantly affect market turnover, volatility, and illiquidity, especially when altering sentiment dynamics.

Journalism Versus Churnalism: How News Factors in Press Releases Affect Journalistic Processing of Ocean Plastic Research in Newspapers Globally

ABSTRACT This study evaluates the impact of news factors in press releases sent from scientific organizations on the representation of ocean plastic research in newspapers. We tracked 84 press releases discussing peer-reviewed ocean plastic studies, published between 2017 and 2021 on EurekAlert! and identified their presence in 495 English-language newspapers worldwide. Text comparison showed that press releases contribute highly to the construction of newspaper articles, with copied text segments in over half of the articles. News factors highlighting the prestige of the scientific study, like research published in high-impact journals or conducted by elite researchers were indicators of high newspaper coverage, as were the news factors bad news, magnitude, and social/economic relevance. Scientific press releases usually provide essential details about research, such as sample characteristics, research sites, and methods. However, funding information and research limitations were only marginally present. This study showed that providing research details does not reduce newsworthiness, instead sometimes even increasing it. Providing research details in press releases can influence journalists’ understanding and evaluation of the scientific study and thereby their decision to report. Hence, to assess the newsworthiness of scientific research, we propose that news factor analysis should include research details.

Novel thermal-regulation and temperature-responsive controlled-release fibermats with porous sheath-core structures

Active regulation of the wound microenvironment as well as on-demand drug delivery have proven to be effective ways to accelerate wound healing, and the development of advanced textiles offers feasibility. A novel fibermat with thermal-regulation and temperature-responsive controlled-release properties was fabricated by using coaxial electrospinning, consisting of porous sheath-core polylactic acid (PLA)/ polyethylene glycol (PEG) fibers. The pore generation in the PLA shell of the PLA/PEG fiber was achieved through a phase separation method. The fiber diameter and pore size of the obtained fiber could be controlled by adjusting the flow rate of shell solution during electrospinning. Increasing the flow rate of shell solution form 0.8 mm·min-1 to 1.4 mm·min-1 resulted in an increase in fiber diameter from 4.8 μm to 15.3 μm, and an increase in pore size from 59.4 nm to 305.6 nm. Due to the high enthalpy and coverage of the PEG core, the PLA/PEG fibermats exhibited excellent thermal-regulation performance, with a surface temperature that was 2.5 °C- 5.6 °C lower than that of pure PLA fibermat during heating process. On-demand release was achieved by directly controlling the core layer of the coaxial PLA/PEG fiber through temperature. The hydrophobicity of the PLA shell initially reduced burst release, followed by increased release as the temperature reached the phase transition temperature of PEG. Furthermore, this advanced fibermat demonstrated desirable moisture permeability, appropriate mechanical properties and good thermal stability, indicating broad potential applications in medical and health fields.

Harnessing the sustainable potential of groundwater in Saudi Arabia via remote sensing

Groundwater resources in water-stressed regions, such as the Middle East, face significant challenges due to low precipitation, high temperatures, and elevated evaporation rates, which are compounded by anthropogenic stresses. In this context, Saudi Aramco (the national petroleum and natural gas company of Saudi Arabia) has contributed in the search for potential groundwater sources to ensure an adequate supply of potable water for the country’s citizens, agricultural needs, and industrial usage. In this study, we combined geographic information system (GIS), remote sensing (RS) and analytic hierarchy process (AHP) techniques to evaluate the vulnerability of groundwater potential (taking Hail as a case study). With a total of 7 thematic layers (i.e., geology, slope, lineament density, land use/land cover, annual rainfall, drainage density, and soil texture), we found that groundwater potential zones with moderate to high coverage account for 91.9%, which is notably close to the borehole data, with a groundwater potential validation accuracy of 90.0%. The obtained results offer a crucial tool for decision-makers and managers, enabling them to develop timely protection and monitoring measures for groundwater resources.

Analysis of spatial and temporal evolution and driving factors of carbon emission in Shandong Province: based on the perspective of land use

Land use/cover change is the second major contributor to carbon emissions, following energy emissions. Studying provincial land-use carbon emissions is crucial for achieving the “double carbon” goal. This study selects 16 prefecture-level cities in Shandong Province as the research object. It analyzes the spatial and temporal distribution pattern of carbon emissions in Shandong Province based on land-use data and energy consumption. In terms of net carbon emissions, this study utilizes the standard deviation ellipse and kernel density estimation to analyze net carbon emissions change from the municipal and regional perspectives. In terms of carbon ecological carrying capacity, not only the carbon ecological carrying capacity of forest and grassland was considered, but also the carbon ecological carrying capacity of crops in Shandong Province, which is a large grain province. Using the geographic detector to explore the drivers. Research findings indicate that carbon sources and sinks show a clear spatial and temporal distribution pattern, with the center of gravity of net carbon emissions extending to the northeast. Areas with high carbon ecological carrying capacity have high forest coverage, grassland coverage, and crop yields. Regarding driving factors, the urbanization rate, economic aggregate, and technological progress demonstrate significant explanatory power through single and interaction tests, suggesting that these factors are critical drivers of land-use carbon emissions within Shandong Province. Based on the spatiotemporal pattern analysis of land-use carbon emissions in Shandong Province, each city's growth rate and spatial distribution characteristics can be clarified, providing a scientific basis for the local government to formulate regional and differentiated emission-reduction policies. In addition, by exploring the driving factors of land-use carbon emissions in Shandong Province, the influence level of factors on carbon emissions can be revealed to provide references for formulating regional sustainable development strategies.

Remotely Sensed Comparative Spatiotemporal Analysis of Drought and Wet Periods in Distinct Mediterranean Agroecosystems

Drought is a widespread natural hazard resulting from an extended period of reduced rainfall, with significant socioeconomic and ecological consequences. Drought severity can impact food security globally due to its high spatial and temporal coverage. The primary objective of this paper consists of a comparative spatiotemporal analysis of environmental extremes (drought/wetness) through the estimation of a twelve-month Standardized Precipitation Index (SPI12) between three distinct vulnerable agricultural regions in the Mediterranean basin (i.e., Spain, Lebanon and Tunisia), under a climate change environment in the last 38 years (1982–2020). The added value of this paper lies in the simultaneous estimation of temporal and spatial variability of drought and wetness periodic events, paying special attention to the geographical patterns of these extremes both in annual and interannual (seasonal) time scales. The results indicated that Spain and Tunisia (western Mediterranean) exhibit similar patterns over the studied period, while Lebanon demonstrates contrasting trends. Comparing the two extreme dry hydrological years, the Spanish study area faced the highest drought intensity, areal extent and duration (SPI12 = −1.18; −1.84; 28–78%; 9–12 months), followed by the Lebanese (SPI12 = −1.28; −1.39; 37–50%; 7–12 months) and the Tunisian ones (SPI12 = −1.05; −1.08; 10–34%; 8 months). Concerning the wettest hydrological years, the Lebanese study domain has recorded the highest SPI12 values, areal extent and duration (SPI12 = 1.58; 2.28; 66–83%; 8–11 months), followed by the Tunisian (SPI12 = 1.55; 1.79; 49–73%; 7–10 months) and Spanish one (SPI12 = 1.07; 1.99; 21–73%; 4–11 months). The periodicity of drought/wetness episodes is about 20 years in Spanish area and 10 years in the Lebanese area (for drought events), whereas there seems no periodicity in the Tunisian one. Understanding the spatial distribution of drought is crucial for targeted mitigation strategies in high-risk areas, potentially avoiding broad, resource-intensive measures across entire regions.

Effects of different mulching technologies on rainfed maize field energy exchange and evapotranspiration partitioning in northwest China

Artificial mulching, a prevalent water-saving tool in arid and semiarid agroecosystems, complicated energy exchange and water transport process between land surface and atmosphere. The field energy and evapotranspiration (ET) partitioning within a soil-mulch-plant-atmosphere continuum have not been comprehensively examined, which limited cognition of the underlying mechanisms that control hydrological processes and achieve yield improvement. Here, a four-season experiment in a rainfed summer maize field with four mulching treatments (NM: non-mulching, SM: straw mulching, RPBF: plastic-mulched ridge with bare furrow, and RPSF: plastic mulched ridge with straw-mulched furrow) was conducted to study the dynamics of surface energy and ET components and their regulation mechanisms. Results indicated that the effects of mulching on field energy partitioning were most evident at the maize initial stage, during which net radiation was significantly decreased under PM treatments (RPBF and RPSF), while soil heat flux was significantly reduced in SM treatments (p < 0.05). The average latent heat flux (LE) was 3.55 and 5.65 MJ·d−1 for NM maize at sowing and seedling stages, but decreased by 9.01 %, 27.04 %, 29.58 % at sowing, and 7.08 %, 9.56 % and 16.46 % at seedling stages for SM, RPBF and PRSF, respectively. The energy component differences among different treatments were minimal during the middle and late stages with high leaf coverage, and total LE and sensible heats were not significantly different. Mulch exerted a notable impact on soil evaporation (E) and crop transpiration (T), characterized by the average E of 0.96, 0.82, 0.57 and 0.46 mm·d−1 in NM, SM, RPBF and RPSF, while the value for T was 1.67, 1.88, 2.03 and 2.10 mm·d−1, respectively. PM conserved soil water by reducing E during the initial growing season and in dry periods, but also enhancing T and deepening the depth of soil water consumption under higher leaf cover. Energy exchange and ET partitioning were found to be more sensitive to soil water content (SWC) during periods characterized by lower leaf coverage, while the role of underlying canopy coverage characteristics overwhelmed soil properties in controlling energy and ET partitioning along with the leaf expansion. These findings contributed to a more comprehensive understanding of different mulching management on rainfed maize energy exchange and water use in Northwest China.

Factors Associated With Appropriateness of Vaccination Age Coverage For Measles Vaccine In Kufa District, Najaf Governorate, Iraq

Measles is one of the diseases that can be effectively managed with vaccination. Herd immunity is a concept that describes the situation where a large proportion of a population is vaccinated, resulting in high coverage rates. Measles infections persist at high levels in specific areas despite the general vaccination rates. Administering the vaccination at the recommended age is crucial for attaining protection and reducing the transmission of vaccine-preventable illnesses . Cross –sectional study was conducted from 1st of OCT .2023 until 25th of JAN. 2024 among mothers with their child aged 12-23 month. The purpose of this study was to assess age-appropriate measles vaccination coverage and associated factors. Collected data using pre-tested questionnaires also data on measles vaccination were taken from vaccination card.This study analyzed 388 mothers, revealing that the majority of father age were between 20-34y, with 41.2% having primary education. Mother age found to be 258(66.5%) between 20-34y .225(57.9%) of father occupation were free job and 334(86.1%) were house wife by occupation, the sex of child 201(51.8%) were found to be female .68.61% were vaccinated with measles vaccine on time, (29.38%) were delayed and (1.80%) were found to be unvaccinated. The education level, number of children in the family and child order are significantly associated with measles vaccination status of child. As we revealed that the proportion of individuals receiving the vaccine within the designated timeframe is below 70%. We should focus on enhancing on time of routine children immunization. This can be achieved by reinforcing existing techniques, developing new approaches, and emphasizing the media's role in promoting the significance of timely vaccine administration.

A novel whole blood assay to quantify the release of T cell associated cytokines in response to Bordetella pertussis antigens

BackgroundBordetella pertussis continues to cause whooping cough globally even in countries with high immunisation coverage. Booster vaccinations with acellular pertussis vaccines are thus used in children, adolescents, and adults. T cell immunity is crucial for orchestrating the immune response after vaccination. However, T cell assays can be expensive and difficult to implement in large clinical trials. In this study, a whole blood (WB) stimulation assay was developed to identify secreted T cell associated cytokines in different age groups after acellular pertussis booster vaccination. Material and methodsLongitudinal WB samples were collected from a small set of subjects (n = 38) aged 7–70 years participating in a larger ongoing clinical trial. For assay development, samples were diluted and incubated with purified inactivated pertussis toxin (PT), filamentous haemagglutinin (FHA), inactivated B. pertussis lysate, and complete medium (M) as stimulating conditions, with anti-CD28 and anti-CD49d as co-stimulants. Different timepoints around the vaccination (D0, D7, D14, D28), WB dilution factor (1:2, 1:4) and incubation time (24 h, 48 h, 72 h) were compared. Responses to 15 cytokines were tested with Luminex/multiplex immunoassay. ResultsThe optimized assay consisted of WB incubation with M, PT, and FHA (including the two co-stimulants). After 48 h incubation, supernatants were collected for measurement of seven selected T cell associated cytokines (IL-2, IL-5, IL-10, IL-13, IL-17 A, IL-17F, and IFN-y) from samples before and 28 days after vaccination. PT stimulation showed a trend for upregulation of IL-2, IL-13, and IL-17 A/F for adult subjects, whereas the responses of all cytokines were downregulated for the paediatric subjects. Furthermore, PT and FHA-stimulated WB showed diverse cytokine producing profiles. ConclusionsThe developed WB-based cytokine assay was shown to be less costly, easy to perform, and functional in differently aged individuals. Further, it requires only a small amount of fresh blood, which is beneficial especially for studies including infants. Our results support the use of this assay for other immunological studies in the future.

HPV Vaccination Coverage in Brazil's State of Paraná: Spatial Distribution and Advances in Public Health.

Background/Objectives: To analyze the spatial distribution of HPV vaccination coverage in relation to sociodemographic variables in a state of Southern Brazil. Methods: This was an ecological, retrospective study with secondary data from the Department of Information Technology of the Unified Health System/Ministry of Health from 2015 to 2022. The cohort method was used to calculate vaccination coverage. Geographically weighted regression was used for the independent variables. Results: There was a 22.04% reduction in vaccination between the first and second doses. Coverage with the first dose of the vaccine reached 95.17% for the female population, 64.67% for the male population, and 79.57% for both sexes. In 50.62% of cities, coverage exceeded 90% for both sexes. In 80.45% of cities, the recommended coverage for females was achieved. The variable municipal performance was positively significant for the increase in vaccination coverage in 45.45% of the regions for girls, 18.18% for boys, and 36.36% for both sexes. The family health strategy variable was significant in 9.09% of the regions for girls and both sexes. The education variable showed an inverse significance for girls in 40.90%, for boys in 18.18%, and for both sexes in 36.36% of the regions. Conclusions: HPV vaccination declined between the first and second doses, with high first-dose coverage among females and moderate coverage among males. Municipal performance notably impacted coverage, particularly for girls. The family health strategy was relevant in specific regions, while educational factors had a variable effect. Addressing these variables may enhance vaccination coverage and minimize the gap between doses.

Does Urban Green Space Pattern Affect Green Space Noise Reduction?

The effect of urban green spaces on traffic noise reduction has been extensively studied at the level of single vegetation, hedges, etc., but there is a lack of corresponding studies at the scale of spatial patterns of urban green spaces. Therefore, this study aims to analyze the relationship between the spatial pattern of urban green space and the change in green space’s noise reduction capacity. Through the morphology spatial pattern analysis method, this analysis divides the urban green space in the Fuzhou high-tech zone into seven types of elements with different ecological definitions and simulates the noise condition of the urban environment with the presence of green space as well as without the presence of green space by computer simulation, calculates the distribution map of the noise reduction produced by the urban green space, and analyzes the correlation between the seven types of green space elements and the noise reduction with the geographically weighted regression modeling analysis. The study finds that (1) Urban green space patterns can significantly affect the net noise reduction of green space. Areas with high green coverage can produce a stronger green space noise reduction effect. (2) More complex green space shapes and more fragmented urban green space can produce higher noise reduction. (3) The green space close to the source of noise can exert a stronger noise reduction effect. Therefore, in the process of planning and design, from the perspective of improving the urban acoustic environment, the configuration of high-quality green spaces in areas with higher levels of noise pollution should be given priority, which may have better noise reduction effects.

Simultaneous integrated boost-intensity modulated radiation therapy (SIBIMRT) planning for pelvic tumours: dose coverage to target volume and normal tissue sparing.

To evaluate the better radiotherapy plan for pelvic tumours that may achieve a high target coverage dose and low normal tissue tolerance dose using simultaneous integrated boost-intensity-modulated radiation therapy technique. The analytical, cross-sectional, descriptive study was conducted from October 2020 to March 2021 at Al- Amal National Hospital for Cancer Treatment, Baghdad, Iraq, and comprised male pelvic cancer patients aged 50-80 years. Computed tomography scans were randomly selected. For each patient, 4 treatment plans (phases Ι and Π) were generated using the simultaneous integrated boost-intensity-modulated radiation therapy technique while keeping all parameters constant except the number of beams, which were 5, 7, 9 and 11. The optimal and safe dose was defined as the one to cover 95% planning target volume. Homogeneity and conformity indices were used to assess the uniformity of dose distribution in the target volume, and various treatment plans in the same patient were compared. Data was analysed using SPSS 24. There were 15 males with mean age 67.12±2.84 years. There was a significant variance in the target volume dose and organ at risk in the 4 different plans generated using the simultaneous integrated boost-intensitymodulated radiation therapy technique (p<0.05). The 9-beam treatment plan was the best for coverage of tumours and protection of healthy organs assessed through homogeneity and conformity indices (p<0.05). The 9-beam treatment plan showed significant tumour coverage, homogeneity and conformity values, and sparing dose for organs at risk.

Dosimetric advantages of adaptive IMPT vs. Enhanced workload and treatment time – A need for automation

IntroductionIn head-and-neck IMPT, trigger-based offline plan adaptation (Offlinetrigger-based) is often used. Our goal was to compare this to four alternative adaptive strategies for dosimetry, workload and treatment time, considering also foreseen further technological advancements, including anticipated automation. Materials and methodsAlternative strategies included weekly offline re-planning (Offlineweekly), daily plan selection from a library (Librarystatic and Libraryprogsressive) and a fast, approximate daily online re-optimization approach (Onlinere-opt). Impact on CTV coverage and NTCPs was assessed by simulations based on repeat-CTs from 15 patients. Full daily re-planning was used as dosimetric benchmark. Increases in workload and treatment time were estimated. ResultsBoth for coverage and NTCPs, fast Onlinere-opt performed as well as full re-planning. Compared to current practice, Onlinere-opt showed enhanced probabilities for high coverage, and resulted in reductions in grade ≥ II NTCPs of 4.6 ± 1.7 %-point for xerostomia and 4.2 ± 2.3 %-point for dysphagia. Offlineweekly and library strategies did not show coverage enhancements and resulted in smaller NTCP improvements. Further automation can largely limit workload and treatment time increases. With anticipated further automation, adaptation-related workload of Offlineweekly, Librarystatic, Libraryprogressive, and Onlinere-opt was expected to increase by 3, 8, 21, and 66 h for 35 fraction treatment courses compared to Offlinetrigger-based. The corresponding adaptation-related prolonged treatment times were estimated to be 0, 4, 6, and 29 min/fraction. ConclusionOnline adaptive strategies could approach dosimetric quality of full re-planning at the cost of additional workload and prolonged treatment time compared to the current offline adaptive strategy. Automation needs to play a key role in making more complex adaptive approaches feasible.

The equity road ahead for financing non-national immunization program vaccines in China: challenges and opportunities from a qualitative study

BackgroundIn China, national immunization program (NIP) vaccines benefit from robust financial support and have achieved high coverage. Non-NIP vaccines rely on fragmented funding sources, mostly out-of-pocket payment, and face sub-optimal and inequitable coverage. Sustainable financing needs to be secured for addressing equity in non-NIP vaccine delivery. However, discussion and understanding of this issue remain limited. This study aims to analyze the current situation, comprehensively identify challenges and opportunities in non-NIP vaccine financing, and offer suggestions to enhance vaccine uptake and improve public health.MethodsBetween July and December 2023, we conducted a series of semi-structured, in-person interviews with 55 stakeholders from the Health Bureau, Centers for Disease Control and Prevention, Medical Insurance Bureau, and Finance Bureau across five provinces in China. Participants were selected through stratified sampling, and the interviews mainly included their involvement in non-NIP vaccine financing, challenges faced, and strategies for improvement to enhance financing performance. Informed consent was obtained, and thematic analysis was used to analyze the data.ResultsNon-NIP vaccine financing sources include out-of-pocket payments, government fiscal, health insurance and other external funds. These four channels differ in vaccine types covered, costs, and target populations, each with unique challenges and opportunities. High out-of-pocket costs remain a significant barrier to equitable vaccine uptake, while market competition has lowered the vaccine price and improved accessibility. Local fiscal support for free vaccination programs faces challenges related to sustainability and regional disparity, though governmental commitment to vaccination is growing. Nevertheless, centralized procurement organized by the government has lowered the price and reduced the financial burden. Despite legal restrictions on using basic health insurance for vaccinations and limited commercial insurance options, private medical savings accounts and mutual-aid mechanisms present new opportunities. Although the scope and impact of external support are limited, it has successfully increased awareness and social attention to vaccination.ConclusionRelying on individual payments as the main financing channel for non-NIP vaccines is unsustainable and inadequate for ensuring universal vaccine access. A concerted and synergistic approach is essential to ensure sufficient, sustainable resources and enhance public financial management to improve equity in the non-NIP vaccines.

Joint HIV and hepatitis C virus phylogenetic analyses signal network overlap among women engaged in sex work and men who purchase sex.

Transmission of HIV and hepatitis C virus (HCV) are heavily influenced by complex interactions within sexual or injecting networks where risk behaviors occur. In Ukraine, women engaged in sex work (WSW) and men who purchase sex (MWPS) are disproportionately affected by both viruses. The aim of our study was to the investigate the influence of underlying networks on transmission of HIV and HCV. A cross-sectional integrated bio-behavioural survey was implemented among 560 WSW and 370 MWPS representative of sex work hotspots in Dnipro, Ukraine (December 2017 to March 2018). A portion of the HIV reverse transcriptase gene (n = 13; 62% WSW, 38% MWPS) and HCV NS5B gene (n = 46; 70% WSW, 30% MWPS) were sequenced from dried blood spot specimens. Tip-to-tip distances on phylogenetic trees were used to infer phylogenetic clusters for identifying potential transmission clusters. Phylogenetic analyses identified two HIV clusters containing four sequences (50% WSW; 50% MWPS) and 11 HCV clusters containing 31 sequences - the majority comprising infections in WSW (83.9%). Nearly half (45.4%) of HCV clusters contained at least one WSW with a history of injecting drugs. Joint analyses of HIV and HCV signal overlap in sex work and injecting networks in Ukraine, suggesting implications for the comprehensive coverage of prevention programs for WSW including harm reduction services. Conducting phylogenetic analyses with HCV may provide a more complete appraisal of underlying transmission networks than HIV alone, particularly in the context of high HIV treatment coverage yielding viral suppression.

Bright compact ultrabroadband source by orthogonal laser-sustained plasma

Laser-sustained plasma (LSP) source featuring high brightness and broadband spectral coverage is found to be powerful in various fields of scientific and industrial applications. However, the fundamental limit of low conversion efficiency constrains the system compactness and widespread applications of such broadband light sources. In this paper, we propose an innovative orthogonal LSP to break through the conversion efficiency limitation. Driven by the elevated conversion efficiency from absorbed laser power to ultraviolet (UV) emission, a compact broadband source (250–1650 nm) with UV spectral radiance exceeding 210 mW/(mm2⋅sr⋅nm)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$${mW}/({{mm}}^{2}\\,\\cdot\\, {sr}\\,\\cdot\\, {nm})$$\\end{document} is achieved with >100 W pump laser. With the plot of a two-dimensional refractive index model, we report an important conceptual advance that the orthogonal design eliminates the influence of the negative lensing effect on laser power density. Experimental results unambiguously demonstrate that we achieve a bright compact UV-VIS-NIR source with negligible thermal loss and the highest conversion efficiency to our knowledge. Significant enhancement of 4 dB contrast-to-noise ratio (CNR) in spectral single-pixel imaging has been demonstrated using the proposed ultrabroadband source. By establishing the quantitative link between pumping optics design and plasma absorption, this work presents a compact broadband source that combines superior conversion efficiency and unprecedented brightness, which is essential to high-speed inspection and spectroscopy applications.

The mitigating effect of social protection on undernourishment during economic downturns: A longitudinal study of 46 low- and middle-income countries over the last two decades

BackgroundLow- and middle-income countries (LMICs) are particularly vulnerable to the adverse effects of economic downturns on the Prevalence of Undernourishment (PoU). Our study aimed to evaluate the impact of Social Protection and Labor Programs (SPL) on PoU in 46 LMICs from 2001 to 2019, and to estimate SPL mitigating effects during economic downturns. MethodsThis cohort study used a multi-country ecological design with two-ways fixed effects multivariable linear regression models, adjusted for relevant demographic, socioeconomic, and contextual variables. Interaction terms between economic downturns and SPL were used to evaluate SPL mitigating effects. FindingsOur study cohort displayed an average 15.30% PoU and 34.34% SPL coverage in the initial year, contrasting with 8.58% PoU and 43.81% SPL coverage in the final year. A 10% SPL coverage was associated with a 0.51% PoU reduction (95%CI: 0.04–0.99) across all countries and 0.78% reduction within the poorest subgroup. SPL have been able to prevent an estimated 1.01 billion (95% UI: 0.16–1.86) cases of undernourishment over the study period in the 46 LMICs. Economic downturns were associated with a 4.55% PoU increase (95% CI: 1.28–7.81) in all countries, and a 6.06% PoU increase in the poorest subgroup. High SPL coverage during the downturns had significant mitigating effects, reducing an overall 1.17% PoU for every 10% SPL coverage in all countries, and 1.81% PoU in the poorest nations. InterpretationAmid the ongoing multiple global crises, expanding the coverage of social protection could effectively mitigate the potential increases in undernourishment during economic downturns, contributing to the achievement of nutrition-related Sustainable Development Goals in LMICs.

Assessment of ethanolic extract of Dittrichia viscosa from Kardoussa Douar region of Taza in Morocco as antioxidant and green inhibitor for carbon steel corrosion in acidic medium

This study targeted evaluating the anticorrosive and antioxidative characteristics of Dittrichia viscosa (ZS-OH) extract. ZS-OH was first extracted by deploying a soxhlet and characterized by chromatographic analysis (GC/MS). In addition, a quantitative assessment of the total phenolic (TPC) and flavonoids (FC) content of the ZS-OH extract, as well as phytochemical analyses, were carried out. Antioxidant testing was conducted using the bioassay: 2,2-diphenyl-1-picrylhydrazyl (DPPH). The ability of ZS-OH extract to stymie the corrosion of carbon steel in 1.0 M HCl was considered through potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). ZS-OH extract yield was 4.73 %, and GC-MS revealed 32 distinct chemicals. Neryl isovalerate (29.8 %), 1,10-di-epi-Cubenol (25.4 %), and 2,5-dimethoxy-p-cymene (11.6 %) made up the majority of the ZS-OH extract. The electrochemical results reveal that the ZS-OH extract acts as a mixed-type with an inhibition efficiency of up to 96.8 % at 500 ppm under 303 K. Surface analyses using SEM/EDS confirmed the formation of the protective layer of ZS-OH extract molecules on the C-S surface. The three major components are fully optimized in the DFT through the B3LYP functional and 6–311++G(d,p) basis sets. Molecular dynamics simulation data show the molecules of ZS-OH extract oriented beneficially on metal surfaces, providing a high surface coverage, and thus, a high inhibition performance.