This paper introduces a new type of cold-formed steel (CFS) built-up closed cross-section (CBC-C) column to connect multi-directional wall panels easily. Axial compression experiments and numerical analysis on 18 columns as well as theoretical calculations are carried out to evaluate the stability and bearing capacity of the proposed column. The effect of factors such as width-to-thickness, slenderness ratios, and screw spacing on the buckling behavior and failure mechanism was studied. As the slenderness ratio increased, the ultimate bearing capacity of specimens with the same section decreased. For specimens with a web width of 140 mm, the ultimate strength increased by 7.35 % when the slenderness ratio was reduced from 26.7 to 3.2. It was observed that the failure modes of short and intermediate long columns were generally local and distortion-related buckling, while the long columns experienced local, distortional, and finally global buckling when the slenderness ratio reached 36.73. The local buckling load and ultimate strength of specimens of the same length and section were reduced with the growth of the width-to-thickness ratio. On average, as the web width-to-thickness ratio increased by 10 %, the local buckling load decreased and the ultimate bearing capacity decreased by 22.37 % and 14.79 %, respectively. It was found that changing the section thickness had a greater effect on the stability and strength of the specimens compared to changing the web width of the CBC-C column. The mechanical properties of the CBC-C were not affected by the screw spacing and the differences among data were less than 5 %. Finally, the effective width method (EWM) and the direct strength method (DSM) in the AISI S100-16 wereassessed for CBC-C. The novel built-up column proposed in this paper has advantages in modular structures for their flexibility in configurations as well as high torsional rigidity and good stability.