The Lipovka and Alabashka ruby occurrences in the Central Urals hosted in marble of the Murzinka–Adui Anticlinorium are considered. The field works were carried out; the chemical compositions of rocks and minerals and oxygen isotopic composition of corundum and silicates were determined; and micas were dated by the K–Ar method. These occurrences are similar in geological environment and mineral assemblages to the ruby occurrences in the South Urals and deposits in Southeast Asia. At the Alabashka occurrence, ruby was also found from brecciated mineralized granite and amphibolite. The mineralized breccia and ruby-bearing marble are enriched in K- and Cr-bearing minerals. Ruby characterized by a narrow range of the oxygen isotopic composition (δ18О = 14.2–17.8‰) corresponding to that of metamorphic and metasomatic corundum. The hydrogen isotopic composition of fuchsite ranges from –78.5 to –89.6‰, while the δD value calculated for fluid equilibrated with fuchsite varies from –48.8 to –79.7‰ that is consistent with the high-temperature equilibrium with magmatic rocks. Aluminum and Cr were mobile elements and could be inflowed by fluids during ruby formation. Corundum mineralization at both occurrenceswas dated at 280–260 Ma, which is consistent with the beginning of post-collisional relaxation. The Murzinka–Adui Anticlinorium is the most prospective area in the Urals for the high-quality ruby deposits.