High Spatial Resolution X-ray Imaging Research Articles

High-Throughput Growth of Armored Perovskite Single Crystal Fibers for Pixelated Arrays.

The poor machinability of halide perovskite crystals severely hampered their practical applications. Here a high-throughput growth method is reported for armored perovskite single-crystal fibers (SCFs). The mold-embedded melt growth (MEG) method provides each SCF with a capillary quartz shell, thus guaranteeing their integrality when cutting and polishing. Hundreds of perovskite SCFs, exemplified by CsPbBr3, CsPbCl3, and CsPbBr2.5I0.5, with customized dimensions (inner diameters of 150-1000µm and length of several centimeters), are grown in one batch, with all the SCFs bearing homogeneity in shape, orientation, and optical/electronic properties. Versatile assembly protocols are proposed to directly integrate the SCFs into arrays. The assembled array detectors demonstrated low-level dark currents (< 1nA) with negligible drift, low detection limit (< 44.84nGys-1), and high sensitivity (61147µCGy-1cm-2). Moreover, the SCFs as isolated pixels are free of signal crosstalk while showing uniform X-ray photocurrents, which is in favor of high spatial resolution X-ray imaging. As both MEG and the assembly of SCFs involve none sophisticated processes limiting the scalable fabrication, the strategy is considered to meet the preconditions of high-throughput productions.

Growth of ultimate high-density scintillating films for high-resolution X-ray imaging at synchrotrons

Scintillators are X-ray to visible light converters applied in X-ray imaging detectors used at synchrotrons. Drastically improved performances of the 4th generation synchrotron sources enable us to perform X-ray imaging experiments at higher energies. For high spatial resolution X-ray imaging (micrometer to submicrometer), thin scintillating films are required. Consequently, especially for high X-ray energies (30keV to 100keV), the detection efficiency is limited due to the low X-ray absorption efficiency of the thin films. We have used Liquid Phase Epitaxy (LPE) to grow thin films of one of the ultimate high-density materials, Lu2Hf2O7:Eu3+, which demonstrate scintillating properties and thus combine high spatial resolution and maximized absorption efficiency. X-ray imaging experiments demonstrate that the Modulation Transfer Function (MTF) reaches 10% at 900 lp/mm, and radiographs visually confirm the promising imaging properties. We present structural, luminescent, and scintillation characterization of Lu2Hf2O7:Eu thin films grown on ZrO2:Y substrates, showing that the films crystallize in the disordered fluorite structure and the europium ions incorporate into the structure and enhance the luminescence intensity. This contribution is a first step toward developing promising ultra-dense, hafnate-based scintillating screens for high spatial resolution X-ray imaging.

The high energy X-ray probe (HEX-P): sensitive broadband X-ray observations of transient phenomena in the 2030s

HEX-P is a probe-class mission concept that will combine high spatial resolution X-ray imaging (&lt;10′′ FWHM) and broad spectral coverage (0.2–80 keV) with an effective area superior to NuSTAR above 10 keV to enable revolutionary new insights into a variety of astrophysical problems, especially those related to compact objects, accretion and outflows. HEX-P will launch at a time when the sky is being routinely scanned for transient gravitational wave, electromagnetic and neutrino phenomena that will require the capabilities of a sensitive, broadband X-ray telescope for follow up studies. These include the merger of compact objects such as neutron stars and black holes, stellar explosions, and the birth of new compact objects. A response time to target of opportunity observation requests of &lt;24 hours and a field of regard of 3π steradians will allow HEX-P to probe the accretion and ejecta from these transient phenomena through the study of relativistic outflows and reprocessed emission, provide unique capabilities for understanding jet physics, and potentially revealing the nature of the central engine.

The high energy X-ray probe (HEX-P): magnetars and other isolated neutron stars

The hard X-ray emission from magnetars and other isolated neutron stars remains under-explored. An instrument with higher sensitivity to hard X-rays is critical to understanding the physics of neutron star magnetospheres and also the relationship between magnetars and Fast Radio Bursts (FRBs). High sensitivity to hard X-rays is required to determine the number of magnetars with hard X-ray tails, and to track transient non-thermal emission from these sources for years post-outburst. This sensitivity would also enable previously impossible studies of the faint non-thermal emission from middle-aged rotation-powered pulsars (RPPs), and detailed phase-resolved spectroscopic studies of younger, bright RPPs. The High Energy X-ray Probe (HEX-P) is a probe-class mission concept that will combine high spatial resolution X-ray imaging (&lt;5 arcsec half-power diameter (HPD) at 0.2–25 keV) and broad spectral coverage (0.2–80 keV) with a sensitivity superior to current facilities (including XMM-Newton and NuSTAR). HEX-P has the required timing resolution to perform follow-up observations of sources identified by other facilities and positively identify candidate pulsating neutron stars. Here we discuss how HEX-P is ideally suited to address important questions about the physics of magnetars and other isolated neutron stars.

The High Energy X-ray Probe (HEX-P): probing accretion onto stellar mass black holes

Accretion is a universal astrophysical process that plays a key role in cosmic history, from the epoch of reionization to galaxy and stellar formation and evolution. Accreting stellar-mass black holes in X-ray binaries are one of the best laboratories to study the accretion process and probe strong gravity—and most importantly, to measure the angular momentum, or spin, of black holes, and its role as a powering mechanism for relativistic astrophysical phenomena. Comprehensive characterization of the disk-corona system of accreting black holes, and their co-evolution, is fundamental to measurements of black hole spin. Here, we use simulated data to demonstrate how key unanswered questions in the study of accreting stellar-mass black holes will be addressed by the High Energy X-ray Probe (HEX-P). HEX-P is a probe-class mission concept that will combine high spatial resolution X-ray imaging and broad spectral coverage (0.2–80 keV) with a sensitivity superior to current facilities (including XMM-Newton and NuSTAR) to enable revolutionary new insights into a variety of important astrophysical problems. We illustrate the capability of HEX-P to: 1) measure the evolving structures of black hole binary accretion flows down to low (≲ 0.1%) Eddington-scaled luminosities via detailed X-ray reflection spectroscopy; 2) provide unprecedented spectral observations of the coronal plasma, probing its elusive geometry and energetics; 3) perform detailed broadband studies of stellar mass black holes in nearby galaxies, thus expanding the repertoire of sources we can use to study accretion physics and determine the fundamental nature of black holes; and 4) act as a complementary observatory to a range of future ground and space-based astronomical observatories, thus providing key spectral measurements of the multi-component emission from the inner accretion flows of black hole X-ray binaries.

The high energy X-ray probe (HEX-P): Resolving the nature of Sgr A* flares, compact object binaries and diffuse X-ray emission in the Galactic center and beyond

HEX-P is a probe-class mission concept that will combine high spatial resolution X-ray imaging (&lt;10″ FWHM) and broad spectral coverage (0.2–80 keV) with an effective area far superior to current facilities’ (including XMM-Newton and NuSTAR). These capabilities will enable revolutionary new insights into a variety of important astrophysical problems. We present scientific objectives and simulations of HEX-P observations of the Galactic Center (GC) and Bulge. We demonstrate the unique and powerful capabilities of the HEX-P observatory for studying both X-ray point sources and diffuse X-ray emission. HEX-P will be uniquely equipped to explore a variety of major topics in Galactic astrophysics, allowing us to 1) investigate broad-band properties of X-ray flares emitted from the supermassive black hole (BH) at Sgr A* and probe the associated particle acceleration and emission mechanisms; 2) identify hard X-ray sources detected by NuSTAR and determine X-ray point source populations in different regions and luminosity ranges; 3) determine the distribution of compact object binaries in the nuclear star cluster and the composition of the Galactic Ridge X-ray emission; 4) identify X-ray transients and measure fundamental parameters such as black hole spin; 5) find hidden pulsars in the Galactic Center; 6) search for BH–OB binaries and hard X-ray flares from young stellar objects in young massive clusters; 7) measure white dwarf (WD) masses of magnetic CVs to deepen our understanding of CV evolution and the origin of white dwarf magnetic fields; 8) explore primary particle accelerators in the GC in synergy with future TeV and neutrino observatories; 9) map out cosmic-ray distributions by observing non-thermal X-ray filaments; 10) explore past X-ray outbursts from Sgr A* through X-ray reflection components from giant molecular clouds.

The high energy X-ray probe (HEX-P): probing the physics of the X-ray corona in active galactic nuclei

The hard X-ray emission in active galactic nuclei (AGN) and black hole X-ray binaries is thought to be produced by a hot cloud of electrons referred to as the corona. This emission, commonly described by a power law with a high-energy cutoff, is suggestive of Comptonization by thermal electrons. While several hypotheses have been proposed to explain the origin, geometry, and composition of the corona, we still lack a clear understanding of this fundamental component. NuSTAR has been playing a key role improving our knowledge of X-ray coronæ thanks to its unprecedented sensitivity above 10 keV. However, these constraints are limited to bright, nearby sources. The High Energy X-ray Probe (HEX-P) is a probe-class mission concept combining high spatial resolution X-ray imaging and broad spectral coverage (0.2–80 keV) with a sensitivity superior to current facilities. In this paper, we highlight the major role that HEX-P will play in further advancing our insights of X-ray coronæ notably in AGN. We demonstrate how HEX-P will measure key properties and track the temporal evolution of coronæ in unobscured AGN. This will allow us to determine their electron distribution and test the dominant emission mechanisms. Furthermore, we show how HEX-P will accurately estimate the coronal properties of obscured AGN in the local Universe, helping address fundamental questions about AGN unification. In addition, HEX-P will characterize coronæ in a large sample of luminous quasars at cosmological redshifts for the first time and track the evolution of coronæ in transient systems in real time. We also demonstrate how HEX-P will enable estimating the coronal geometry using spectral-timing techniques. HEX-P will thus be essential to understand the evolution and growth of black holes over a broad range of mass, distance, and luminosity, and will help uncover the black holes’ role in shaping the Universe.

The high energy X-ray probe (HEX-P): Galactic PeVatrons, star clusters, superbubbles, microquasar jets, and gamma-ray binaries

HEX-P is a probe-class mission concept that will combine high spatial resolution X-ray imaging (&lt;10″ FWHM) and broad spectral coverage (0.2–80 keV) with an effective area far superior to current facilities (including XMM-Newton and NuSTAR) to enable revolutionary new insights into a variety of important astrophysical problems. With the recent discoveries of over 40 ultra-high-energy gamma-ray sources (detected above 100 TeV) and neutrino emission in the Galactic Plane, we have entered a new era of multi-messenger astrophysics facing the exciting reality of Galactic PeVatrons. In the next decade, as more Galactic PeVatrons and TeV gamma-ray sources are expected to be discovered, the identification of their acceleration and emission mechanisms will be the most pressing issue in both particle and high-energy astrophysics. In this paper, along with its companion papers, we will present that HEX-P is uniquely suited to address important problems in various cosmic-ray accelerators, including Galactic PeVatrons, through investigating synchrotron X-ray emission of TeV–PeV electrons produced by both leptonic and hadronic processes. For Galactic PeVatron candidates and other TeV gamma-ray sources, HEX-P can fill in a large gap in the spectral-energy distributions (SEDs) of many objects observed in radio, soft X-rays, and gamma rays, constraining the maximum energies to which electrons can be accelerated, with implications for the nature of the Galactic PeVatrons and their contributions to the spectrum of Galactic cosmic rays beyond the knee at ∼3 PeV. In particular, X-ray observation with HEX-P and TeV observation with CTAO will provide the most powerful multi-messenger diagnostics to identify Galactic PeVatrons and explore a variety of astrophysical shock mechanisms. We present simulations of each class of Galactic TeV–PeV sources, demonstrating the power of both the imaging and spectral capabilities of HEX-P to advance our knowledge of Galactic cosmic-ray accelerators. In addition, we discuss HEX-P’s unique and complementary roles to upcoming gamma-ray and neutrino observatories in the 2030s.

The High Energy X-ray Probe (HEX-P): supernova remnants, pulsar wind nebulae, and nuclear astrophysics

HEX-P is a probe-class mission concept that will combine high spatial resolution X-ray imaging (&lt;10″ full width at half maximum) and broad spectral coverage (0.2–80 keV) with an effective area far superior to current facilities (including XMM-Newton and NuSTAR) to enable revolutionary new insights into a variety of important astrophysical problems. HEX-P is ideally suited to address important problems in the physics and astrophysics of supernova remnants (SNRs) and pulsar wind nebulae (PWNe). For shell SNRs, HEX-P can greatly improve our understanding via more accurate spectral characterization and localization of non-thermal X-ray emission from both non-thermal-dominated SNRs and those containing both thermal and non-thermal components, and can discover previously unknown non-thermal components in SNRs. Multi-epoch HEX-P observations of several young SNRs (e.g., Cas A and Tycho) are expected to detect year-scale variabilities of X-ray filaments and knots, thus enabling us to determine fundamental parameters related to diffusive shock acceleration, such as local magnetic field strengths and maximum electron energies. For PWNe, HEX-P will provide spatially-resolved, broadband X-ray spectral data separately from their pulsar emission, allowing us to study how particle acceleration, cooling, and propagation operate in different evolution stages of PWNe. HEX-P is also poised to make unique and significant contributions to nuclear astrophysics of Galactic radioactive sources by improving detections of, or limits on, 44Ti in the youngest SNRs and by potentially discovering rare nuclear lines as evidence of double neutron star mergers. Throughout the paper, we present simulations of each class of objects, demonstrating the power of both the imaging and spectral capabilities of HEX-P to advance our knowledge of SNRs, PWNe, and nuclear astrophysics.

Interlayer-Spacing Engineering of Lead-Free Perovskite Single Crystal for High-Performance X-Ray Imaging.

Lead-free A3 Bi2 I9 -type perovskites are demonstrated as a class of promising semiconductors for high-performance X-ray detection due to their high bulk resistivity and strong X-ray absorption, as well as reduced ion migration. However, due to their long interlamellar distance along their c-axis, their limited carrier transport along the vertical direction is a bottleneck for their detection sensitivity. Herein, a new A-site cation of aminoguanidinium (AG) with all-NH2 terminals is designed to shorten the interlayer spacing by forming more and stronger NH···I hydrogen bonds. The prepared large AG3 Bi2 I9 single crystals (SCs) render shorter interlamellar distance for a larger mobility-lifetime product of 7.94×10-3 cm2 V-1 , which is three times higher than the value measured on the best MA3 Bi2 I9 SC (2.87 ×10-3 cm2 V-1 ). Therefore, the X-ray detectors fabricated on the AG3 Bi2 I9 SC exhibit high sensitivity of 5791 uCGy-1 cm-2 , a low detection limit of 2.6nGy s-1, and a short response time of 690µs, all of which are far better than those of the state-of-the-art MA3 Bi2 I9 SC detectors. The combination of high sensitivity and high stability enables astonishingly high spatial resolution (8.7 lpmm-1 ) X-ray imaging. This work will facilitate the development of low-cost and high-performance lead-free X-ray detectors.

Demonstration of the X-ray imaging capabilities of the newly installed multilayer monochromator at SPring-8 BL20B2

Double multilayer monochromators (DMMs) for 40 keV and 110 keV have been installed at BL20B2 in SPring-8. The DMMs provide X-rays with a few percent bandwidths at those energies. The flux density of the X-rays is more than several hundred times higher than that of monochromatic X-rays with a silicon double crystal monochromator, which enables us to perform high-speed X-ray imaging with a large field of view and high spatial resolution X-ray imaging in those high-energy X-rays. Here characteristics of DMMs and some demonstrations of X-ray imaging using the high flux density beams are shown.

2D perovskite-based high spatial resolution X-ray detectors

X-ray radiography is the most widely used imaging technique with applications encompassing medical and industrial imaging, homeland security, and materials research. Although a significant amount of research and development has gone into improving the spatial resolution of the current state-of-the-art indirect X-ray detectors, it is still limited by the detector thickness and microcolumnar structure quality. This paper demonstrates high spatial resolution X-ray imaging with solution-processable two-dimensional hybrid perovskite single-crystal scintillators grown inside microcapillary channels as small as 20 µm. These highly scalable non-hygroscopic detectors demonstrate excellent spatial resolution similar to the direct X-ray detectors. X-ray imaging results of a camera constructed using this scintillator show Modulation Transfer Function values significantly better than the current state-of-the-art X-ray detectors. These structured detectors open up a new era of low-cost large-area ultrahigh spatial resolution high frame rate X-ray imaging with numerous applications.

Coupled x-ray high-speed imaging and pressure measurements in a cavitating backward facing step flow

The two-phase flow generated behind a cavitating backward-facing step is studied using the combination of three experimental techniques: wall-pressure measurements, global high-speed imaging with visible light, and high spatial and temporal resolution x-ray imaging. Three zones are identified based on the topology of the vapor fraction maps, that correspond to vaporization, transport, and condensation. Simultaneous pressure and void fraction measurements reveal that extreme events are associated with a change from a shear layer mode to a wake mode, with a temporal signature that is heavily affected by the presence of the vapor phase.

Experimental investigation of wet pharmaceutical granulation using in-situ synchrotron X-ray imaging

Observing and measuring wet granulation processes of pharmaceutical powders is challenging with conventional experimental methods due to their opacity and the complex interaction that happens in a short time. In this study, synchrotron in-situ imaging technique was employed to capture the dynamic granulation process with a single drop impacting method. Two common pharmaceutical excipients and an active pharmaceutical ingredient (API) were used as the powder beds. Three liquids were used as binders. A new parameter, overall movement ratio, rm, is introduced to quantitatively describe the movement of the liquid binders in the powder beds. The dynamic interactions between the liquid binder and solid powders were captured via high temporal and spatial resolution X-ray images. Results show that particles with smaller sizes have the tunneling mechanism, and the spreading mechanism occurs with larger particles, as expected. Liquid binder properties including viscosity and contact angle, and operation parameters including droplet release height and volume show significant impacts on the dynamic granulation process. This study demonstrates the potential of using in-situ synchrotron X-ray imaging to quantitatively study the dynamic wet granulation process.

Characterization of Fine-Pixel X-Ray Imaging Detector Array Fabricated by Using Thick Single-Crystal CdTe Layers on Si Substrates Grown by MOVPE

A novel approach for developing a large area, high-spatial-resolution X-ray imaging detector is presented. This approach uses metal–organic vapor phase epitaxy grown thick single-crystal CdTe layers grown directly on Si substrates. The detector consists of a p-CdTe/n-CdTe/n+-Si heterojunction diode structure, where the n-CdTe and the p-CdTe layers are successively grown on the n+-Si substrate. An array of ( $128\times128$ ) pixels was formed on the p-CdTe side, where each pixel is $60~\mu \text{m}^{\textsf {2}}$ in an 80- $\mu \text{m}$ pixel pitch. The detector array was bump bonded to a charge integration-type CMOS readout ASIC. The basic performance of this detector was evaluated by measuring the dark currents, the X-ray generation currents as well as taking the X-ray images of some objects. The results were promising which confirmed that the detector developed can be applied in high spatial resolution X-ray imaging.

Visible photoluminescence of aggregate colour centres in lithium fluoride thin films for low-energy proton beam radiation detectors at high doses

Colour centres (CCs) in lithium fluoride (LiF) are well known for application in tuneable lasers and dosimeters. The visible photoluminescence (PL) of radiation-induced, broad-band light-emitting aggregate CCs in LiF crystals and films has been proposed for high spatial resolution X-ray imaging; use of LiF-based detectors has been recently successfully extended to advanced diagnostics of low-energy proton beams. After exposure, transversal dose mapping was obtained on LiF films by acquiring the visible PL image of the irradiated spots in a fluorescence microscope under blue-light pumping.Irradiation of thermally evaporated LiF thin films with a proton beam of 3 MeV nominal energy, produced by a linear accelerator, in the fluence range of 1011–1015 protons/cm2, induces the formation of stable CCs, mainly the primary F centre and the aggregate F2 and F3+ defects. A comparison with irradiations performed at 7 MeV shows that the spectrally integrated PL as a function of the absorbed dose is independent on the selected beam energy, at least as far as typical LiF film thicknesses are concerned. The PL behaviour vs. dose can be described by a linear growth which covers up to three order of magnitude, followed by saturation at high values (> ≈105 Gy). The spectral contributions of F2 and F3+ CCs to the detected PL, in the red and in the green respectively, under laser pumping were carefully analysed in order to investigate behaviour differences of these defects at high doses.

Performance study of double SOI image sensors

Double silicon-on-insulator (DSOI) sensors composed of two thin silicon layers and one thick silicon layer have been developed since 2011. The thick substrate consists of high resistivity silicon with p-n junctions while the thin layers are used as SOI-CMOS circuitry and as shielding to reduce the back-gate effect and crosstalk between the sensor and the circuitry. In 2014, a high-resolution integration-type pixel sensor, INTPIX8, was developed based on the DSOI concept. This device is fabricated using a Czochralski p-type (Cz-p) substrate in contrast to a single SOI (SSOI) device having a single thin silicon layer and a Float Zone p-type (FZ-p) substrate. In the present work, X-ray spectra of both DSOI and SSOI sensors were obtained using an Am-241 radiation source at four gain settings. The gain of the DSOI sensor was found to be approximately three times that of the SSOI device because the coupling capacitance is reduced by the DSOI structure. An X-ray imaging demonstration was also performed and high spatial resolution X-ray images were obtained.

Development of vertically aligned ZnO-nanowires scintillators for high spatial resolution x-ray imaging

Newly designed scintillator of (0001)-oriented ZnO vertical nanowires (vnws) for X-ray imaging was prepared on a Ga-doped ZnO/soda-lime glass by electrodeposition, and the light emission feature was estimated in a synchrotron radiation facility. The ZnO-vnws scintillator revealed a strong light emission and improved resolution on CMOS image compared with that for the ZnO-layer scintillator, although the light emission performance was deteriorated in comparison to the Lu3Al5O12:Ce3+. The light emission property closely related to the nanostructure and the resultant photoluminescence characteristic.

Pinhole diffraction holography for fabrication of high-resolution Fresnel Zone Plates

Fresnel zone plates (FZPs) play an essential role in high spatial resolution x-ray imaging and analysis of materials in many fields. These diffractive lenses are commonly made by serial writing techniques such as electron beam or focused ion beam lithography. Here we show that pinhole diffraction holography has potential to generate FZP patterns that are free from aberrations and imperfections that may be present in alternative fabrication techniques. In this presented method, FZPs are fabricated by recording interference pattern of a spherical wave generated by diffraction through a pinhole, illuminated with coherent plane wave at extreme ultraviolet (EUV) wavelength. Fundamental and practical issues involved in formation and recording of the interference pattern are considered. It is found that resolution of the produced FZP is directly related to the diameter of the pinhole used and the pinhole size cannot be made arbitrarily small as the transmission of EUV or x-ray light through small pinholes diminishes due to poor refractive index contrast found between materials in these spectral ranges. We also find that the practical restrictions on exposure time due to the light intensity available from current sources directly imposes a limit on the number of zones that can be printed with this method. Therefore a trade-off between the resolution and the FZP diameter exists. Overall, we find that this method can be used to fabricate aberration free FZPs down to a resolution of about 10 nm.

Applications of non-periodic multilayer optics for high-resolution x-ray microscopes below 30 keV

Multilayer mirrors with enhanced bandwidth were developed with special performances for dense plasma diagnostics and mainly for high spatial resolution x-ray imaging. The multilayer coatings are designed to provide broadband x-ray reflectance at low grazing incidence angles. They are deposited onto toroidal mirror substrates. Our research is directed at the development of non-periodic (depth graded) W∕Si multilayer specifically designed for use in the 1 to 30 keV photon energy band. First, we present a study for a 5 to 22 keV x-ray spectral window at 0.45° grazing angle. The goal is to obtain a high and constant reflectivity. Second, we have modeled a broadband mirror coating for harder x-rays in the range from 10 to 30 keV, with a non-periodic structure containing 300 W∕SiC layers with periods in the range from 0.8 to 4 nm, designed for 0.35° grazing incidence angle.