ABSTRACTThe aim of this study was to describe the lifestyles of undergraduate students, examine patterns and identify predictor variables and specific subpopulations at risk. The participants were 1,879 students from a Chilean university who answered an online survey. Overall results indicated that the participants’ dietary patterns were unhealthy with some gender-based differences. Only 23.7% of the sample exercised regularly, 30% exhibited problematic alcohol consumption and 90.5% claimed responsible sexual behavior. The latent class analysis identified four homogenous lifestyle classes. There is only one group that represents the 17.20% of the sample, which met the majority of the healthy behavior criteria. One group was characterized as highly risky, their members exhibited poor diet; lack of exercise; and higher prevalence of smoking, drug use and problematic alcohol consumption.Students who lived with families and engaged in religious and sporting activities had a greater likelihood of belonging to the groups with healthier lifestyles. Being male, between the ages of 22 and 24 with a higher level of social self-concept were more likely to belong to the group that exhibit high-risk lifestyle behavior.These findings reinforce the need to address health promotion in a meaningful manner and may help in the identification of high-risk students.