Current ISO standards that pertain to water-resistance testing with inkjet prints were developed for moisture-impermeable RC photo papers and do not take into account the kinds of ink diffusion behavior that can occur with inkjet printing on highly absorbent plain papers, especially with dye-based inks. Contact with water with plain paper documents can result in significant lateral ink bleeding, migration of inks through the paper to the backside of the sheet, transfer of ink from one sheet to adjacent sheets, and two-way transfer of inks with double-sided printed documents. Shipping labels and envelopes can become illegible should they become wet, and Barcodes and QR codes may be rendered completely unreadable. This study attempts to better understand the water-resistance behavior of plain paper documents printed with dye-based and pigment inkjet inks. The use of high-resolution multispectral imaging and colorimetric analysis systems to provide a quantitative assessment of ink bleeding, migration, and ink transfer to adjacent pages is explored as an alternative to the subjective, qualitative, water-resistance evaluation methods specified in current ISO standards.