High Levels Of Polycyclic Aromatic Hydrocarbons Research Articles

The key metabolic signatures and biomarkers of polycyclic aromatic hydrocarbon-induced blood glucose elevation in chinese individuals exposed to diesel engine exhaust

Due to the complexity of environmental exposure factors and the low levels of exposure in the general population, identifying the key environmental factors associated with diabetes and understanding their potential mechanisms present significant challenges. This study aimed to identify key polycyclic aromatic hydrocarbons (PAHs) contributing to increased fasting blood glucose (FBG) concentrations and to explore their potential metabolic mechanisms. We recruited a highly PAH-exposed diesel engine exhaust testing population and healthy controls. Our findings found a positive association between FBG concentrations and PAH metabolites, identifying 1-OHNa, 2-OHPh, and 9-OHPh as major contributors to the rise in FBG concentrations induced by PAH mixtures. Specifically, each 10 % increase in 1-OHNa, 2-OHPh, and 9-OHPh concentrations led to increases in FBG concentrations of 0.201 %, 0.261 %, and 0.268 %, respectively. Targeted metabolomics analysis revealed significant alterations in metabolic pathways among those exposed to high levels of PAHs, including sirtuin signaling, asparagine metabolism, and proline metabolism pathway. Toxic function analysis highlighted differential metabolites involved in various dysglycemia-related conditions, such as cardiac arrhythmia and renal damage. Mediation analysis revealed that 2-aminooctanoic acid mediated the FBG elevation induced by 2-OHPh, while 2-hydroxyphenylacetic acid and hypoxanthine acted as partial suppressors. Notably, 2-aminooctanoic acid was identified as a crucial intermediary metabolic biomarker, mediating significant portions of the associations between the multiple different structures of OH-PAHs and elevated FBG concentrations, accounting for 16.73 %, 10.84 %, 10.00 %, and 11.90 % of these effects for 1-OHPyr, 2-OHFlu, the sum concentrations of 2- and 9-OHPh, and the sum concentrations of total OH-PAHs, respectively. Overall, our study explored the potential metabolic mechanisms underlying the elevated FBG induced by PAHs and identified 2-aminooctanoic acid as a pivotal metabolic biomarker, presenting a potential target for intervention.

Chronological evaluation of polycyclic aromatic hydrocarbons in sediments of tangxun lake in central China and impacts of human activities.

This study sheds light on the contamination of polycyclic aromatic hydrocarbons (PAHs) in Tangxun Lake sediments, an urban lake reflecting environmental changes in Central China. By analyzing sediment cores from both the inner and outer areas of the lake, we determined the historical trends and sources of PAHs over the past century. The results reveal a significant increase in PAHs concentrations, particularly since the 1980s, coinciding with China's rapid urbanization and industrialization. Using diagnostic ratios and Absolute principal component score-multivariate linear regression (APCS-MLR) methods, we identified petroleum combustion, coal combustion, and biomass combustion as the primary sources of PAHs in the lake sediments. The spatial analysis indicates higher PAHs levels in the inner lake, likely due to its closer proximity to industrial activities. Moreover, by comparing PAH trends in Tangxun Lake with those in other urban, suburban, and remote lakes across China, based on data from 49 sedimentary cores, we highlight the impact of regional socio-economic dynamics on PAH deposition. These insights are crucial for developing effective pollution mitigation strategies and promoting sustainable development in rapidly urbanizing regions.

Personal exposure monitoring to polycyclic aromatic hydrocarbons bound to size-segregated aerosol

Air pollution is a global problem, where impaired air quality significantly damages human health and the environment. Twenty-four hours of personal exposure to size-segregated airborne particulate matter (PM) and associated polycyclic aromatic hydrocarbons (PAHs) were measured in 129 non-smoking residents living in two Czech cities, Ostrava (an industrial area with high levels of air pollution) and Ceske Budejovice (an agricultural area with lower air pollution level) in various seasons between years 2018–2020. Particulate matter (PM) was sampled by cascade impactors based on their aerodynamic diameter (dae, μm) and divided into size fractions: coarse (2.5 < dae), fine (0.25 < dae < 2.5) and ultrafine (<0.25). Size distributions of 20 priority PAHs adsorbed on these PM fractions were analyzed by gas chromatography coupled to tandem mass spectrometry in electron ionization (GC-EI-MS/MS). The total concentration of ∑20PAHs to which residents were exposed ranged from 0.09 ng/m3 to 47.18 ng/m3. A higher level of PAHs was detected in Ostrava (mean: 5.59 ng/m3) than in Ceske Budejovice (mean: 1.96 ng/m3). Statistically significant concentration differences between PAHs in individual seasons were observed in both sampled localities, with higher concentrations measured in winter than in summer. Fine and ultrafine particles predominated in the mass composition of the particulate matter. The ultrafine particle size contained 67–80% of total PAHs. Respiratory health risk was estimated based on inhalation cancer risk (ICR). Cancer risk attributable to personal inhalation exposure ranged from 2.8 × 10−8 to 4.3 × 10−4. In winter, higher cancer risk were found in Ostrava, mainly caused by a high concentration of carcinogenic PAHs bound to ultrafine particles. Overall, the personal monitoring data confirmed a higher air pollution burden in the industrial area and the winter season and highlighted the importance of focusing on ultrafine particles as the main carriers of potentially mutagenic and carcinogenic substances, such as PAHs. In addition, personal monitoring data provided more detailed and accurate information on individual-level exposures, revealing significant differences in exposure concentrations in people living in the same area.

Concentration of Polycyclic Aromatic Hydrocarbons in Water from Hand-dug Wells in Some Communities in Ekpeyeland, Rivers State, Nigeria

Well water sources from selected communities in Ekpeyeland were assessed for the concentrations of polycyclic aromatic hydrocarbons (PAHs). The assessment was conducted seasonally in six communities. The concentrations of the PAHs were determined using standard methods and procedures and finally quantified by the use of GC-MS chromatography. The result showed the presence of all the 16 USEPA priority PAHs in the examined water samples. Seasonal variations were not significant. The summed values of PAHs from stations and seasons were above the permissible limit required for by WHO. Classification of the different categories of PAHs identified higher molecular weight (HMW) PAHs more in concentration than lower molecular weight (LMW) PAHs in the wells. Source identification proved that both pyrogenic and petrogenic sources were responsible for the presence of PAHs in the well water. However, pyrogenic source was the more prominent source of PAHs in the water. There was high level of carcinogenic PAHs in the water and thus the water portends danger to the users. Therefore, the locals are advised not to consume the water to avoid its effect on the long run.

Analyzing the Presence and Dispersion of Hydrocarbons at Mechanic Workshop Dumpsites, Port Harcourt, Rivers State, Nigeria

The study aimed to analyze the presence and dispersion of hydrocarbons in dumpsites at mechanic workshops in Port Harcourt, Rivers State, Nigeria. Soil samples were collected from within 15-25 cm soil depth from three mechanic workshops in Port Harcourt, situated at Elekahia, Rumeme and Eleme Local Governments. The total petroleum (TPH) and Polycyclic aromatic hydrocarbons (PAHs) concentrations in the soil samples were determined using standard methods. Total TPH concentration in mechanic workshop dumpsites ranged from 9508.18 ppm to 10342.41 ppm, while in the control the concentration was 424.41 ppm. Total PAH concentration in mechanic workshop dumpsites ranged from 312.45 ppm to 1654.08 ppm, while in the control the concentration was 157.89 ppm. All the dumpsites had high levels of PAHs, which was several folds more than in the control. Results revealed that soil at mechanic workshop dumpsites was highly contaminated with hydrocarbons, exceeding the allowable limit 50 mg/kg by the Department oof Petroleum Resources (DPR). Remediation of the soil is recommended, as well as proper management of waste, where relocation of the dumpsite is not possible.

Associations between Urinary Concentrations of Polycyclic Aromatic Hydrocarbons and Overactive Bladder in US Adults: Data from the National Health and Nutrition Examination Survey 2005–2016

Introduction: Polycyclic aromatic hydrocarbons (PAHs) are a group of chemicals that can induce oxidative stress and related cytotoxicity. Whether urinary concentrations of PAHs have effects on overactive bladder (OAB) in the general population is still unclear. This study investigated the associations between urinary PAHs and OAB. Methods: 7,146 adults aged over 20 who participated in the US National Health and Nutrition Examination Survey 2005–2016 were studied. The impact of the six PAHs on OAB was evaluated by multivariate logistic regression, and percent changes related to different quartiles of those six PAH levels were calculated. Confounders including age, logarithmic urinary creatinine, gender, race, body mass index, educational level, marriage, poverty income ratio, diabetes, hypertension, and metabolic syndrome were controlled. Results: There is a significant positive correlation between urinary concentrations of the six PAHs we include in the study and the occurrence of OAB. Furthermore, individuals with higher PAH levels also reported a more severe OAB symptom score (OABSS). Conclusions: Our findings revealed that adult men in the USA with higher urinary PAHs had a higher risk of OAB incidence. These findings suggest the importance of strong environmental regulation of PAHs to protect population health. However, the underlying mechanisms still need further exploration.

Assessing the Formation of Polycyclic Aromatic Hydrocarbons in Grilled Beef Steak and Beef Patty with Different Charcoals by the Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) Method with Gas Chromatography-Mass Spectrometry.

This study investigated the effects of different charcoals on the occurrence of 16 polycyclic aromatic hydrocarbons (PAHs) in grilled beef steaks and beef patties. Seven different charcoals were used as follows: from oak wood (C1), from orange wood (C2), from Valonia oak wood (C3), from Marabu wood (C4), extruded charcoal from beech wood (C5), from coconut shells (C6), and from hazelnut shells (C7). The grilling times for each charcoal type were 6 min for the beef patties and 7 min for the beef steaks, until the internal temperature reached at least 74°C. The total concentration of 16 PAHs (PAH16) in beef steaks grilled with C1 (35.75 μg/kg) and C7 (36.39 μg/kg) was higher than that of C3 (23.80 μg/kg) and C6 (24.48 μg/kg; p<0.05). The highest amounts of PAH16 (216.40 μg/kg) were determined in the beef patty samples grilled using C5 (p<0.05). The summation of benzo[a]anthracene, chrysene, benzo[b]fluoranthene and benzo[a]pyrene, referred to as PAH4, was not detected in any of the beef steaks, whereas it was determined in the beef patties grilled with C2 (7.72 μg/kg) and C5 (22.95 μg/kg; p<0.05). The PAH16 concentrations of the beef patty samples in each charcoal group were significantly higher compared to the beef steaks (p<0.05). To avoid the formation of high PAH levels, the use of extruded charcoal and hazelnut shell charcoal should therefore be avoided when charcoal grilling beef steaks and beef patties, and low-fat meat products should be preferred.

Recent Evidence on Polycyclic Aromatic Hydrocarbon Exposure.

This review provides a comprehensive conclusion of the relationship between the intake of various polycyclic aromatic hydrocarbons (PAHs) and different dietary patterns, pointing to the accompanying potential health risks. To achieve this, existing pertinent research was collected and analyzed. The collation revealed that the concentration of PAHs in food and their dietary patterns were diverse in different regions. Specifically, the concentration of PAHs in food was found to be related to the level of pollution in the area, including soil, air, and water pollution, which is then accumulated through the food chain into food that can be ingested directly by the human body, resulting in malformations in offspring, increased risk of cancer, and gene mutation. Guidebooks and dietary surveys were consulted to uncover disparities in dietary patterns, which indicated regional variations in taste preferences, traditional foods, and eating habits. Different regions are spatially categorized in this assessment by cities, countries, and continents. Notably, smoking and grilling are two of the food processing methods most likely to produce high levels of PAHs. To prevent excessive intake of PAHs from food items and attain a higher quality of life, more health education is urgently needed to promote healthy eating patterns.

Sources of Polycyclic Aromatic Hydrocarbons in Fecal Pellets of a Marphysa Species (Annelida: Eunicidae) in the Yoro Tidal Flat, Japan.

The fecal pellets of Marphysa sp. E sensu Abe et al. (2019) (Annelida, Eunicidae) living in the Yoro tidal flat (Ichihara, Chiba, Japan) contain high levels of polycyclic aromatic hydrocarbons (PAHs), and the concentrations rapidly decrease over time. To investigate the origin of the high-concentration PAHs in the fecal pellets and food sources of the worms, the PAH concentrations, carbon and nitrogen stable isotope ratios (δ13C and δ15N), total organic carbon, and total nitrogen for two types of sediment (sands and reduced muds), fecal pellets, and the body of the worms were determined. The PAH concentrations and chemical properties of the fecal pellets were similar to those of the reduced muds (20-30 cm sediment depth). The δ13C, δ15N, and C/N values of reduced muds were the same as the typical values of terrestrial C3 plants, suggesting that reduced muds were derived from terrestrial plants. These data indicated that the worms selectively take up reduced muds containing high levels of PAHs. The δ13C and δ15N values of the worm bodies indicated that the worms did not use the organic carbon derived from terrestrial C3 plants as primary nutrition. Taking into consideration their selective uptake of reduced muds, excretion, and subsequent rapid decrease of PAHs in the fecal pellets, the worms could contribute to the remediation of chemical pollutants in the tidal flat sediments.

Determination of Polycyclic Aromatic Hydrocarbons in the Water of Ijegun-Egba Community of Lagos State, Nigeria

Introduction: Polycyclic Aromatic Hydrocarbons (PAHs) are common pollutants in water that have been reported to cause severe health effects in humans and harm the ecosystem. Aims: This study examined the concentrations of PAHs in different water sources used for domestic purposes in Ijegun- Egba community. Materials and Methods: Twenty-four (24) groundwater samples were collected from four sites in Ijegun-Egba. The Physicochemical parameters were determined using standard methods and PAHs were determined through Gas chromatography-flame – Flame ionization detector. Results: The appearance, odour, and temperature were within the limits of World Health Organisation (WHO). Conductivity levels were within the WHO limit (2,500µS/cm) in well water (1,400µS/cm) and borehole water (1,470 µS/cm) except for river water (4,432.5 µS/cm) which was above WHO recommended limit (2,500µS/cm). pH was within limits in all sites studied except for borehole water (pH =4.0). Among the 16 PAHs, Naphthalene (NAPH) was generally the most abundant PAH (23.89% to Σ16PAHs). There was a significant difference (at &lt; 0.005) in the level of PAHs in the four sources of water. Conclusion: River water has the highest level of PAHs. This points to the activities of the tank farms and suggests that petrol and oil deposits find themselves either through percolation, soil runoffs, or erosion into the water bodies. The Lagos State Environmental Protection Agency should continue to monitor the activities of oil tankers in Ijegun community oil deports. Truck stations should be built outside the community and the residents should avoid the use of water from rivers in Ijegun community.

Spatial and individual factors mediate the tissue burden of polycyclic aromatic hydrocarbons in adult and chick brown pelicans in the northern Gulf of Mexico

The northern Gulf of Mexico supports a substantial level of oil and gas extraction in marine waters and experiences acute and chronic exposure to marine pollution events. The region also supports a diverse array of breeding and migratory seabirds that are exposed to these pollutants during foraging and other activities. Among the pollutants of highest concern within the region are polycyclic aromatic hydrocarbons (PAHs) which tend to be toxic, carcinogenic, mutagenic, or teratogenic. We assessed PAH loads in blood from adult brown pelicans and from feathers of adults and chicks of brown pelicans in relation to individual (e.g., body condition, sex) and spatial (e.g., breeding location within the Gulf, home range size, migration distance) factors. Of the 24 PAHs assessed, 17 occurred at least once among all samples. There were no PAHs found in chicks that were not also found in adults. Alkylated PAHs occurred more commonly and were measured at higher summed concentrations compared to parent PAHs in all samples, indicating that exposure to oil and/or byproducts of oil may have been a substantial source of PAH contamination for brown pelicans during this study. Within adults, PAHs were more likely to occur, and to increase in concentration, in blood samples of females compared to males, although no difference was found in feather samples. We also found that occurrence of and concentration of PAHs increased in adults that migrated longer distances. In adults and chicks, the background levels of oil and gas development within the region of the colony was not a consistent predictor of the presence of or concentration of PAHs. We also found correlations of PAHs with hematological and biochemical biomarkers that suggested compromised health. Our results indicate that both short- and long-term exposure (i.e., blood and feathers, respectively) are occurring for this species and that even nest-bound chicks can accumulate high levels of PAHs. Long-term tracking of PAHs, as well as an assessment of sublethal effects of PAHs on pelicans, could enhance our understanding of the persistence and effects of this contaminant in the northern Gulf as could increasing the breadth of species studied.

Evaluation of the Formation of Polycyclic Aromatic Hydrocarbons (PAHs) in Chicken Cooked by Saudi Traditional Methods and Their Dietary Risk Assessment

This study evaluates the formation of 13 polycyclic aromatic hydrocarbons (PAHs) in chicken thighs and breasts, cooked by different methods. These methods are: madhbi, charcoal mandi, electric oven mandi, gas flame oven mandi and shawaya. Chicken samples were collected from a restaurant in Riyadh, Saudi Arabia. Analysis of the samples was carried out using high-performance liquid chromatography with a fluorescence detector (HPLC-FLD). The data obtained showed that madhbi chicken had higher PAHs levels than other cooking styles, with the mean concentration in chicken breast of 87.72 µg/kg and thigh of 75.56 µg/kg. Phenanthrene was the compound detected at the highest concentration in different cooking methods. There was no significant difference in concentration of PAHs between the parts of chicken cooked with the same method. However, the method of cooking had a significant impact on the formation of PHAs. Therefore, the formation of PAHs in chicken meat could be reduced by choosing appropriate cooking methods. Moreover, the margin of exposure was used to assess the health risk in adults due to madhbi chicken ingestion. The results showed that there is no serious health concern.

Investigating industrial PAH air pollution in relation to population exposure in major countries: A scoring approach

Polycyclic aromatic hydrocarbons (PAHs) are common air pollutants worldwide, associated with industrial processes. In the general population, both modeling and field studies revealed a positive correlation between air PAH concentrations and urinary PAH metabolite levels. Many countries lack population urinary data that correspond to local PAH air concentrations. Thus, we proposed a scoring-based approximate approach to investigating that correlation in selected countries, hypothesizing that PAH air concentrations in selected regions could represent the national air quality influenced by industrial emission and further correlate to PAH internal exposure in the general population. This research compiled 85 peer-reviewed journal articles and 9 official monitoring datasets/reports covering 34 countries, 16 of which with both atmospheric PAH data and human biomonitoring data. For the air pollution score (AirS), Egypt had the highest AirS at 0.94 and Pakistan was at the bottom of the score ranking at −1.95, as well as the median in the UK (AirS: 0.50). For the population exposure score (ExpS), China gained the top ExpS at 0.44 and Spain was with the lowest ExpS of −1.52, with the median value in Italy (ExpS: 0.43). Through the correlation analysis, atmospheric PAHs and their corresponding urinary metabolites provided a positive relationship to a diverse extent, indicating that the related urinary metabolites could reflect the population's exposure to specific atmospheric PAHs. The findings also revealed that in the 16 selected countries, AirS indexes were positively correlated with ExpS indexes, implying that higher PAH levels in the air may lead to elevated metabolite urinary levels in general populations. Furthermore, lowering PAH air concentrations could reduce population internal PAH exposure, implying that strict PAH air regulation or emission would reduce health risks for general populations. Notably, this study was an ideal theoretical research based on proposed assumptions to some extent. Further research should focus on understanding exposure pathways, protecting vulnerable populations, and improving the PAH database to optimize PAH pollution control.

The combined effect of heavy metals and polycyclic aromatic hydrocarbons on arthritis, especially osteoarthritis, in the U.S. adult population

The evaluation of heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs) impact on arthritis is usually limited to the analysis of the arthritis subtype (rheumatoid arthritis, RA), whereas studies on osteoarthritis (OA) are relatively sparse. Furthermore, the combined effect of HMs and PAHs co-exposure on arthritis also has rarely been analyzed. Herein, we aimed to comprehensively estimate the association between HMs and PAHs (three blood HMs and six urinary PAHs metabolites) co-exposure and arthritis. Using data from the National Health and Nutrition Examination Survey (NHANES), 2003–2016, we included 9735 adults, of whom 2464 had total arthritis, 1371 had OA, and 468 had RA. The logistic regression model was conducted to estimate the single effect of HMs and PAHs on arthritis. Moreover, weighted quantile sum (WQS) regression, quantile-based g computation (qgcomp), and Bayesian kernel machine regression (BKMR) were separately performed to assess the combined effect of HMs and PAHs co-exposure on arthritis. In the single-exposure analyses, cadmium (Cd) and lead (Pb) statistically grew the risk of total arthritis, OA, and RA. Among PAHs, 1-hydroxynaphthalene (1-NAP) and 3-hydroxyfluorene (3-FLU) showed a positive association with total arthritis, OA, and RA. Meanwhile, 2-NAP also was significantly associated with total arthritis. 2-NAP, 2-FLU, and 1-hydroxyphenanthrene (1-PHE) also were significantly associated with RA. Furthermore, the three complementary models consistently demonstrated that co-exposure to high levels of HMs and PAHs was positively associated with total arthritis, OA, and RA risk. The above associations were more obvious in young and medium-aged people. Interestingly, BKMR analyses indicated that 1-NAP might interact with Cd and 3-FLU in total arthritis, while Pb might interact with Cd in OA. Therefore, this study provided novel evidence that co-exposure to HMs and PAHs positively correlated with arthritis, especially OA, and these results were worthy of further prospective studies.

Concentration of Polycyclic Aromatic Hydrocarbons (PAHs) in Human Serum and Adipose Tissues and Stimulatory Effect of Naphthalene in Adipogenesis in 3T3-L1 Cells.

Polycyclic aromatic hydrocarbons (PAHs) are one of the most prevalent classes of environmental pollutants. Some evidence shows that PAHs could be involved in human obesity. However, little is known about the distribution patterns of PAHs in human adipose tissue (AT) and the role of PAHs on adipogenesis/lipogenesis. The aims of this pilot study were to determine concentrations of 16 PAHs defined as high-priority pollutants in the plasma and adipose tissue of French and Polish bariatric patients, as well as their correlation with body mass index (BMI), plasma and AT adipokines expression levels. We finally investigated the role of naphthalene on cell proliferation, viability, and differentiation in 3T3-L1 preadipocytes. The concentration of most PAHs was similar in the three types of AT and it was significantly higher in AT as compared to plasma, suggesting bioaccumulation. Polish patients had higher PAH levels in AT than French ones. Only the concentration of naphthalene in AT was positively correlated with the BMI and serum or adipose chemerin, adiponectin and resistin expression, in French but not in Polish patients, who had significantly higher BMIs. Moreover, naphthalene exposure increased the cell proliferation of 3T3-L1 preadipocytes and lipogenesis, and increased the expression of genes involved in adipogenesis after cell differentiation. Taken together, PAHs and more particularly naphthalene could be an obesogenic molecule and increase the risk of obesity.

Association of Polycyclic Aromatic Hydrocarbons exposure with sleep quality among coking plant workers

Objective: To explore the relationship between polycyclic aromatic hydrocarbons (PAHs) exposure and sleep quality in workers from a coking plant. Methods: From April to June 2019. Selected 632 employed workers in the coking plant of a large state-owned enterprise in Shanxi Province as the exposed group, and 477 employed workers in the water-pump plant belonged to the same enterprise as the control group. We used self-designed questionnaires to collect the basic information of subjects. We measured the concentrations of 12 PAHs in the peripheral blood of workers using gas chromatography-mass spectrometry (GC-MS) ; Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the sleep quality of workers; The relationship between plasma PAHs concentration and sleep quality was analyzed using multiple linear regression model, restricted cubic spline (RCS) regression and logistic regression. Results: The concentration of 12 polycyclic aromatic hydrocarbons in the peripheral blood of the exposure group was (2.36±1.46) ng/ml, which was significantly higher than that of the control group (2.19±1.21) ng/ml. The detection rate of sleep disorder in the exposure group (18.0%) was higher than that in the control group (16.8%) , which was manifested by the significantly increased scores in subjective sleep quality, sleep latency, sleep disorders, daytime dysfunction, and PSQI. Multiple linear regression analysis showed that the PSQI score of workers in the high exposure group decreased by 0.80 (95% CI: -1.40~-0.19) points compared with the low exposure group, with a statistically significant difference (P<0.05) . RCS analysis showed a non-linear dose-response relationship of PSQI score with PAHs cumulative exposure (plasma PAHs concentration multiplied by length of service) . The results of logistic regression showed that compared with the low level group, the risk of somnipathy in the middle level group of PAHs cumulative exposure decreased by 44%, among which the risk of sleep disorder in the drinkers decreased by 40%, while the risk of somnipathy in the high level group increased by 96% compared with the low level group. Stratified analysis of alcohol drinking habit showed non-significant difference in PSQI score with low, medium, and high levels of PAHs cumulative exposure in non-drinkers (P>0.05) , and that the PSQI score was significantly increased in alcohol drinkers with high level of PAHs cumulative exposure compared to those with low and medium levels of PAHs cumulative exposure. Conclusion: The workers in the coking plant had high levels of PAHs in plasma and poor sleep quality, Higher level of PAHs cumulative exposure (>1396.56ng/ml) is a risk factor of poor sleep quality.

Polycyclic aromatic hydrocarbons in Fildes Peninsula, maritime Antarctica: Effects of human disturbance

This study provides the first data on the distribution, sources, and transport dynamics of polycyclic aromatic hydrocarbons (PAHs) in Fildes Peninsula, Antarctica via summertime analyses of lakes, seawater, snow, and air in 2013. Relatively high PAH levels and similar composition profiles (dominance of two- and three-ring PAHs) in the investigated marine and terrestrial environmental matrices were found, indicating substantial primary emissions of petrogenic PAHs. This result was corroborated by nonequilibrium partitioning of atmospheric PAHs caused by release of anthropically-derived lighter PAHs and air mass movement trajectories mainly originated from the Antarctic marginal seas. Notable geographical disparities of PAH pollution in the various types of samples consistently suggested impacts of station-related activities, rather than long-range atmospheric transport, on PAHs in Fildes Peninsula. The lack for temperature dependence for gas-phase concentrations and various molecular diagnostic ratios of atmospheric PAHs demonstrated that the impact of local anthropogenic inputs on air PAH variability supersedes the re-emission effect. The derived air–water and air–snow exchanges of PAHs in this remote region indicated a disequilibrium state, partially associated with intense local emissions of PAHs. PAH outgassing from, and absorption into, lake and marine waters were both observed, probably due to differences in anthropogenic influences among sites, while the net deposition of gaseous PAHs into snow prevailed. The results of this study shed lights on the major importance of native anthropogenic sources in the footprint and fate of PAHs in the Fildes Peninsula, which merits further monitoring.

Polycyclic aromatic hydrocarbons in commercial tea from China and implications for human exposure

Tea consumption may increase the level of human exposure to polycyclic aromatic hydrocarbons (PAHs), while relevant health risks are unclear. This study collected 218 samples of five categories of tea (dark, green, black, oolong, and white) from seven major tea sources in China. High performance liquid chromatography was used to determine the concentrations of 16 common PAHs. The concentration of all 16 PAHs (ΣPAHs) varied from 11.4 to 1251 ng/g, with a median value of 86.4 ng/g. Of the five tea categories from the seven source provinces, the median ΣPAHs concentration values were ordered as 189 ng/g (dark tea) > 110 ng/g (oolong tea) > 83.3 ng/g (green tea) > 49.7 ng/g (black tea) > 33.7 ng/g (white tea). Dark tea from Hunan had the highest level of PAHs, and white tea was the least contaminated with PAHs. The 3-ring PAHs and 4-ring PAHs were dominant in tea. The sources of PAHs in tea were mainly attributed to grass, wood, and coal combustion. The median margin of exposure (MOE) and incremental lifetime cancer risk (ILCR) values of benzo(a)pyrene (BaP) were 4.22E+ 04 and 6.86E-06 (dark tea), 8.14E+ 04 and 3.55E-06 (green tea), 1.71E+ 05 and 1.69E-06 (black tea), 4.97E+ 04 and 5.88E-06 (oolong tea), 7.42E+ 05 and 3.89E-07 (white tea), respectively. The results showed that chronic exposure to PAHs via the consumption of dark, oolong, black, and green tea, can result in a carcinogenic risk to humans, which should be a public health concern.

Toxicity determination, pollution source delineation, and microbial diversity evaluation of PAHs-contaminated sediments for an urban river.

The Feng-Sang River is a metropolitan river in Kaohsiung City, Taiwan. In this study, Feng-Sang River sediments were analyzed to investigate the distributions and sources of polycyclic aromatic hydrocarbons (PAHs). The Sediment Quality Guidelines (SQGs), potentially carcinogenic PAHs (TEQcarc), and toxic equivalence quotient (TEQ) were applied to evaluate influences of PAHs on ecosystems and microbial diversities. Results indicate that PAHs concentrations varied between seasons and locations. The concentrations of ∑16PAHs ranged from 73.6 to 603.8 ng/kg in dry seasons and from 2.3 to 199.3 ng/kg in wet seasons. This could be because of the flushing effect during wet seasons, which caused the movement and dilution of the PAH-contaminated sediments. Diagnostic ratio analysis infers that high PAHs levels were generated by combustion processes and vehicle traffic, and results from multivariate descriptive statistical analysis also demonstrate that the vehicular traffic pollution could be the major emission source of PAHs contamination. Comparisons of PAHs with SQGs indicate that PAHs concentrations in sediment were below the effects range low (ERL) values, and thus, the immediate threat to organisms might not be significant. The diagnostic ratio analyses are effective methods for PAH source appointment. The metagenomic assay results imply that sediments contained essential microbial species with eminent diversity. The detected PAH-degrading bacteria (Desulfatiglans, Dechloromonas, Sphingomonas, Methylobacterium, Rhodobacter, Clostridium, and Exiguobacterium) played a key role in PAHs biotransformation, and Dechloromonas and Rhodobacter had a higher relative abundance. Results of microbial diversity analyses indicate that the contaminated environment induced the changes of governing microbial groups in sediments. PRACTITIONER POINTS: Diagnostic ratio analyses are effective methods for PAHs source appointment. Microbial composition in sediments are highly affected by anthropogenic pollution. Combustion and vehicle traffic contribute to urban river sediments pollution by PAHs. Dechloromonas and Rhodobacter are dominant PAHs-degrading bacteria in sediments.

Occurrence and sources of microplastics and polycyclic aromatic hydrocarbons in surface sediments of Svalbard, Arctic.

Due to the distinct environment condition and geographic location, Svalbard has been recognized as a potential pollution reservoir in the Arctic. In this study, 8 surface sediment samples were collected from two fjords in Svalbard (Kongsfjorden and Rijpfjorden) in 2017, and they were searched for microplastics and polycyclic aromatic hydrocarbons (PAHs). PAHs were also investigated in 10 soil samples of Ny-Ålesund for local anthropogenic source analysis. The level of microplastics and other anthropogenic particles ranged from not detected (ND) to 4.936 particles/kg dry weight (DW). Fiber was the only shape of the microplastics found and three polymers (polyester, rayon and cellulose) were detected, which suggested that fisheries-related debris and textile materials were possible sources of microplastics and anthropogenic particles. For PAHs, the level of ∑26PAH was 9.2ng/g to 67.1ng/g (DW), and were dominated by lnP and BghiP, indicating petroleum combustion source. Further analysis revealed that traffic emissions from cars and diesel combustion from a local power plant were major sources of PAHs in soils of Ny-Alesund, while traffic emissions from ships were the dominate source of PAHs in sediments of Kongsfjorden and Rijpfjorden. A higher level of PAHs was observed in Ny-Alesund, confirming an anthropogenic input, while transport via ocean currents might contribute to the higher abundance of microplastics in Rijpfjorden. Further research and even long-term observation of pollutants are needed to fully understand the pollution status in polar regions.