Highest Number Of Publications Research Articles

Mapping the landscape: a bibliometric analysis of resting-state fMRI research on schizophrenia over the past 25 years

Schizophrenia, a multifaceted mental disorder characterized by disturbances in thought, perception, and emotion, has been extensively investigated through resting-state fMRI, uncovering changes in spontaneous brain activity among those affected. However, a bibliometric examination regarding publication trends in resting-state fMRI studies related to schizophrenia is lacking. This study obtained relevant publications from the Web of Science Core Collection spanning the period from 1998 to 2022. Data extracted from these publications included information on countries/regions, institutions, authors, journals, and keywords. The collected data underwent analysis and visualization using VOSviewer software. The primary analyses included examination of international and institutional collaborations, authorship patterns, co-citation analyses of authors and journals, as well as exploration of keyword co-occurrence and temporal trend networks. A total of 859 publications were retrieved, indicating an overall growth trend from 1998 to 2022. China and the United States emerged as the leading contributors in both publication outputs and citations, with Central South University and the University of New Mexico being identified as the most productive institutions. Vince D. Calhoun had the highest number of publications and citation counts, while Karl J. Friston was recognized as the most influential author based on co-citations. Key journals such as Neuroimage, Schizophrenia Research, Schizophrenia Bulletin, and Biological Psychiatry played pivotal roles in advancing this field. Recent popular keywords included support vector machine, antipsychotic medication, transcranial magnetic stimulation, and related terms. This study systematically synthesizes the historical development, current status, and future trends in resting-state fMRI research in schizophrenia, offering valuable insights for future research directions.

Orthopedic Surgery Matched Applicants Are Publishing More: A Bibliometric Analysis of Research Output.

Introduction This studyanalyzed the number of peer-reviewed publications submitted by matriculants prior to applying for the orthopedic surgery residency. The graduating residency classes of 2023 and 2027 were included in the study to understand the trend of publications, to inform aspiring orthopedic surgeons. Methods The top, middle, and bottom 10 orthopedic surgery residency programs were identified on the Doximity online website. Matriculants were searched on PubMed and Google Scholar for publication contributions. Variables including number of publications, orthopedic publications, first-author authorship, and H-index were analyzed. A logistic regression model was created, and a t-test was conducted to statistically compare the 2027 and 2023 graduating classes. Results Matriculants of the 2023 match had higher numbers of publications, orthopedic surgery-specific publications, first authorships, and h-indices than the matriculants of the 2018 match. Conclusion The average number of publications has been observed to increase over four years, indicating an increase in competition to match into orthopedic surgery residency. Publishing in higher numbers may be a good indicator of an applicant's success in not only matching but also matching into a higher-tier program.

Insights into the history and tendency of glycosylation and digestive system tumor: A bibliometric-based visual analysis.

Glycosylation, a commonly occurring post-translational modification, is highly expressed in several tumors, specifically in those of the digestive system, and plays a role in various cellular pathophysiological mechanisms. Although the importance and detection methods of glycosylation in digestive system tumors have garnered increasing attention in recent years, bibliometric analysis of this field remains scarce. The present study aims to identify the developmental trends and research hotspots of glycosylation in digestive system tumors. To find and identify the developmental trends and research hotspots of glycosylation in digestive system tumors. We obtained relevant literature from the Web of Science Core Collection and employed VOSviewer 1.6.19 and CiteSpace (version 6.1.R6) to perform bibliometric analysis. A total of 2042 documents spanning from 1978 to the present were analyzed, with the research process divided into three phases: the period of obscurity (1978-1990), continuous development period (1991-2006), and the rapid outbreak period (2007-2023). These documents were authored by researchers from 66 countries or regions, with the United States and China leading in terms of publication output. Reis Celso A had the highest number of publications, while Pinho SS was the most cited author. Co-occurrence analysis revealed the most popular keywords in this field are glycosylation, expression, cancer, colorectal cancer, and pancreatic cancer. Furthermore, the Journal of Proteome Research was the most prolific journal in terms of publications, while the Journal of Biological Chemistry had the most citations. The bibliometric analysis shows current research focus is primarily on basic research in this field. However, future research should aim to utilize glycosylation as a target for treating tumor patients.

Current status and trends in island ecosystem services research: A bibliometric analysis from 2000 to 2023

With the continuous development of the social economy, ecosystem services are very important for human production and living ecology, and human activities also affect the health of ecosystem services. However, there has yet to be a systematic review of sea island ecosystem services worldwide. This study aimed to use bibliometric analysis to provide a comprehensive review of the progress of research on island ecosystem services from 2000 to 2023 and an outlook on future research directions. This paper analyzed 730 publications that were related to island ecosystems during this period, covering 42 countries, 1252 institutions, and 3160 authors. The results showed that the country with the most research contributions in this field was the United States, which was followed by China and the United Kingdom. Among the research institutions, the cooperation among institutions was relatively single and fixed, and the Chinese Academy of Sciences had the highest number of publications and citations. Keyword clustering and emergence analysis showed that “ecosystem services”, “urban heat island”, and “climate change” were the main themes, while “InVEST model”, “ecological vulnerability model”, and “GEE (google earth engine)” were the most commonly used research techniques and tools. The results showed that the relationship between human drivers and island ecosystem services is a hot topic in current research, and nature-based solutions and the conservation of island ecosystem services may be the direction for future research. This study provides valuable insights and future research directions in the field of island ecosystem services to better define research topics and identify appropriate research partners.

Research on Family-Centered Care in pediatric patients: A Bibliometric Analysis

ObjectiveThis study is conducted as a bibliometric analysis to determine the trends in studies related to family-centered care in children. Materials and methodsThe Web of Science database was used to collect study data. A search was conducted on Web of Science using the keywords “family-centered care”, “family centered care”, “family-centred care”, “family centred care”, “family-integrated care”, “family integrated care”, “patient and family centered care”, “patient- and family-centered care” and “child” or “pediatric” or “pediatrics” or “child” or “newborn” or “neonatal” or “adolescent” together. The VOSviewer program was used for data analysis and visualization. The analysis included the number of publications by year, distribution by journals, most cited studies, countries with the highest publication output, most frequently used keywords, and co-authorship dimensions, presented with visual maps. ResultsA total of 2525 studies conducted from 1980 onwards were analyzed. The analysis revealed that the initial publications related to the subject emerged in 1980, and the United States was identified as the country with the highest number of publications, based on the Web of Science database. The Journal of Pediatric Nursing: Nursing Care of Children and Families (JPN) was determined as the journal with the highest number of publications, while the journal receiving the most citations was PEDIATRICS. ConclusionThe study found an increasing importance given to the Family-Centered Care Approach since the 1980s, with a majority of studies being descriptive in nature. It was determined that the studies were concentrated in the USA indicating a lack of global interest in the Family-Centered. Practical implicationsNursing researchers can build upon this study in the field of family-centered care by conducting more specific and in-depth investigations. This contributes to adding new information to the nursing literature and filling gaps in this area.

Worldwide productivity and research trend of publications concerning SIAD: a bibliometric study.

Syndrome of inappropriate antidiuretic(SIAD) occurs secondary to various diseases, which is characterised by hypotonic hyponatremia and impaired urinary diluting capacity. Research on SIAD in both domestic and international contexts has a long history. This study objectively and comprehensively analyses the research trends, hotspots and development of SIAD research of the past 20 years using the method of bibliometric analysis. The 2003-2022 data in the Web of Science Core Collection database were searched. The Bibliometrix software package, VOSviewer and CiteSpace were used to mine, extract and visualise the retrieved literature, and the generated maps were used in analysing the main topics and trends in the field of SIAD research. A total of 1215 articles published in 623 journals were included in the analysis, with a total of 18,886 citations. Results showed that the research output on SIAD has continuously increased in the past 20 years, and the United States had the highest number of publications and citations. Keywords with the highest burst strength in recent years were the most mentioned keywords, in addition to the search terms 'hyponatremia', 'covid-19', and 'mortality'. Thus, the relationship among SIAD, covid-19 and mortality may become research frontiers and trends. Fifteen milestone articles were identified through co-citation analysis, which mainly focused on the pathophysiology and treatment of SIAD. Based on bibliometric analysis and knowledge mapping, this study summarises development trends in the field of SIAD research, providing references for current and future research into SIAD.

Folic acid conjugated poly(propylene imine) dendrimer as a nanomedicine tool for targeted drug delivery: Bibliometric analysis using google scholar indexed vosviewer

By using bibliometric analysis and data mapping with the help of the VOSViewer program, this study aims to examine the breadth of research on the subject of folic acid-conjugated PPI dendrimers for targeted drug delivery. Data was collected from the Google Scholar scientific document database using the Harzing Publish or Perish 8 application. Journal articles containing the keywords "dendrimer," "PPI," "folic acid," and "drug delivery" that were published in the years 2018 through 2023 were used as the selection criteria for the data. The selection results in the form of 221 journal articles were analyzed and mapped. The total number of research publications has increased from 2018-2021 with the highest number of publications being 64 articles (in 2021). Research publications related to the topic experienced a decline in 2022-2023 due to the global COVID-19 pandemic. The items that are very closely related to the topic have the keywords drug delivery system, treatment, cancer, and ligand. This bibliometric analysis is expected to help researchers identify research trends and recommend future research prospects.

Preresidency research output among US neurological surgery residents.

Research productivity is often used to evaluate candidates for neurosurgery residency. Official annual reports describe the mean total number of research products of successful applicants for each match cycle; however, the average number of indexed publications, the highest-valued research product, is not reported separately from other research products. The primary objectives of this study were to describe the distribution of preresidency indexed publication quantity among successful neurosurgery applicants from 2017 to 2021 and determine whether any change in publication quantity across application cycles existed. Secondary objectives included determining the rate at which the average publication quantity is increasing across application cycles, whether this increase is driven by high-output applicants alone, and if a performance ceiling has been reached. US doctor of medicine seniors applying to the senior author's institution between 2017 and 2021 and who successfully matched into any US neurosurgery program were included. Publication quantities were extracted using Scopus. Additional variables were extracted from residency applications. Mean (SD) and median (IQR) publication quantities were used to describe the distribution and compare across years. Applicants were ranked by descending publication count and divided into quartiles. Averages within each quartile were compared with respective quartiles across years. Averages of the top 10% most productive applicants were compared across years to determine if a performance ceiling existed. Overall, 93.2% of matched applicants were captured. The mean and median total numbers of publications for applicants who matched from 2017 to 2021 were 5.6 ± 8.3 and 3.0 (1.0, 7.0), respectively. The mean and median numbers of publications increased from 3.7 ± 5.3 and 2.0 (0.0, 5.0) in 2016-2017 to 8.1 ± 10.0 and 5.0 (2.0, 11.0) in 2020-2021 (p < 0.001). The distribution of publication quantity was right-skewed. Multivariable analysis determined the application year to be independently and positively correlated with publication quantity (β 1.07 [95% CI 0.71-1.42], p < 0.001). All quartiles observed an increased average number of publications across years (p < 0.001). The mean and median numbers for the top 10% increased from 15.8 ± 8.7 and 13.0 (10.8, 15.5) in 2016-2017, respectively, to 31.3 ± 16.0 and 25.0 (21.0, 35.5) in 2020-2021 (p < 0.001). Indexed publications account for a small portion of the total research products that successful neurosurgery candidates list on applications. A high number of publications is not necessary for candidates to match, with approximately 50% of all applicants who successfully matched having ≤ 5 publications and 25% having ≤ 2 publications. The average preresidency publication quantity has been increasing yearly among neurosurgery applicants. This increase was present across the applicant pool. Additionally, no performance ceiling was observed.

Bibliometric analysis of scientific production on botulinum toxin and dentistry: Collaboration, impact, and trends

Abstract Aim: To conduct a detailed examination of the scientific literature on the topic of botulinum toxin in relation to dentistry, using bibliometric analysis methods. Materials and Methods: This study employed a retrospective and descriptive design with a bibliometric approach. The research focused on the intersection of botulinum toxin and dentistry, analyzing articles published from 2018 to 2023. This search was conducted on September 21, 2023. These articles were then organized and analyzed through metadata analysis. The selection criteria were defined based on the PICO question. Inclusion criteria encompassed research articles related to botulinum toxin and dentistry, published between 2018 and 2023, available in Scopus, and containing the specified keywords. Exclusion criteria were set to omit review articles, editorials, letters to the editor, commentaries, articles not written in English, articles that had not undergone peer review, and those whose full text was not accessible. This approach allowed for an objective measurement of variables using SciVal from Scopus, ensuring the reliability and validity of the study findings. The progressive increase in scientific production on botulinum toxin and dentistry over the last five years was thus effectively captured and analyzed. Results: From 2018 to 2023, the scientific production on botulinum toxin and dentistry was higher in Q2 and Q1. 2019 was the only year where there were a higher number of publications in Q1, since in the other years the publications were mostly in Q2. The scientific journal with the highest average of publications on this topic was the British Journal of Oral and Maxillofacial Surgery. Most of the publications were from Peking University, China, and the Universidade de Sao Paulo. The most prolific author was Paulo César Rodrigues Conti, and the countries with the most publications on botulinum toxin and dentistry were the United States and Brazil. Conclusions: During the last five years, the scientific production on botulinum toxin and dentistry has progressively increased, with most of the publications being in the Q2 and Q1 quartiles. The United States was the country with the highest number of publications. The author, Paulo César Rodrigues Conti, was the researcher with the highest average manuscripts.

Comprehensive bibliometric and visualized analysis of research on gut-liver axis published from 1998 to 2022

BackgroundThe concept of the gut-liver axis was proposed by Marshall in 1998, and since then, this hypothesis has been gradually accepted by the academic community. Many publications have been published on the gut-liver axis, making it important to assess the scientific implications of these studies and the trends in this field. MethodsPublications were retrieved from the Web of Science Core Collection. Microsoft Excel, CiteSpace, VOSviewer, and Scimago Graphica software were used for bibliometric analysis. ResultsA total of 776 publications from the Web of Science core database were included in this study. In the past 25 years, the number of publications on the gut-liver axis has shown an upward trend, particularly in the past 3 years (2020–2022). China had the highest number of publications (267 articles, 34.4%). However, the United States was at the top regarding influence and international cooperation in this field. The University of California San Diego had contributed the most publications. Suk, Ki Tae and Schnabl, Bernd were tied for the first rank in most publications. Thematic hotspots and frontiers were focused on gut microbiota, microbial metabolite, intestinal permeability, bacterial translocation, bile acid, non-alcoholic steatohepatitis, and alcoholic liver disease. ConclusionOur study is the first bibliometric analysis of literature using visualization software to present the current research status of the gut-liver axis over the past 25 years. The damage and repair of intestinal barrier function, as well as the disruption of gut microbiota and host metabolism, should be a focus of attention. This study can provide a reference for later researchers to understand the global research trends, hotspots, and frontiers in this field.

Bibliometric Analysis of Studies of Published in the Field of Volatility

Volatility, which is used to determine the risk structure of financial markets or instruments, is one of the most used methods by researchers. In this study which is conducted to reveal the tag of volatility studies, 11,894 articles related to volatility between 1975 and 2020, which were scanned in the Web of Science database, were subjected to bibliometric analysis. As a consequence of the investigation, the details of the subject such as the country with the highest number of publications, institutions, the most cited authors, articles, leading journals and keywords in the field were revealed. As a consequence of the, it was determined that the authors worked on three basic subjects such as "stocks and stock markets", "exchange rates" and "macroeconomic indicators" on volatility. It has been observed that the main objectives of the studies conducted are either to compare the performance of existing volatility estimation models or to develop new models by adding new variables.

Bibliometric and visualized analysis of reporting and data systems from 2000 to 2022: research situation, global trends, and hotspots.

The reporting and data system (RADS) has been researched across the world since it was first developed. This study used bibliometrics to analyze the research trends and current status of this field over the past almost 23 years and explored possible future research hotspots. We searched the Web of Science (WOS) literature on RADSs from January 1, 2000, to November 1, 2022, and evaluated the findings visually with VOSviewer (1.6.18), CiteSpace (6.1.3), and the "bibliometrix" package in R version 4.2.1. We included 6,239 publications from 88 countries and regions. The number of published has shown an overall growth trend, especially since 2016. The United States was the country with the highest number of publications and citations. The top 10 most productive institutions in RADS research were mainly from South Korea and the United States. Kim EK was the most published author, and Turkbey B had the most cited publication. European Radiology had the most publications on the subject, while Radiology was the most influential journal. Magnetic resonance imaging, carcinoma, ultrasound, RADS, mammography, breast neoplasms, and diagnosis were the most common keywords. Artificial intelligence (AI) appears to be an emerging hotspot in the research of RADS. This study provides an overview of the development status of research into RADSs over the past 23 years. Research into RADSs has included various systems of the body, with the most studied being the breast, prostate, liver, and thyroid. In terms of auxiliary diagnosis, there is an increasing amount of research into the application of AI in RADSs, which along with the interpretability of AI, will be a hotspot of research in the following years.

Systematic review on effects of global climate change on birds

AbstractConsequences of climatic change in migratory and resident birds in terms of behavior, physiology, genetics, ecology, and evolution are the best documented changes reported in the animal world. This systematic review focuses on the studies conducted/published in the two most recent decades (2001–2020) regarding the effects of global climate change on birds. The PSALSAR [Protocol, Search, Appraisal, Synthesis, Analysis and Reporting results] approach was used to conduct the review. Information from a total of 170 publications in two databases (PUBMED and Google Scholar) including journal articles, books, book chapters, reviews, and reports were extracted and analyzed under ten criteria. An increase in publication number was observed in both databases. Overall, the highest number of publications were available for the year 2019. The highest number (141) of selected publications were journal articles. The highest number of articles (41) were from PLOS One. Selected articles’ study periods ranged between 1830 to 2100. Twenty‐eight studies were done in a global scale. Other studies scaled around eight regions, five continents and 40 countries. Behavior and ecology related consequences were studied the most. Eighty‐two studies used primary data sources and 88 studies used secondary data sources. Quantification, mapping, and modeling were the most utilized modes of assessments. Most studies species are Pied Flycatcher (Ficedula hypoleuca), Blue Tit (Cyanistes caeruleus), and Tree Swallow (Tachycineta bicolor). Majority of the publications were based on expansion of knowledge.

Visualization Analysis of Artificial Intelligence Literature in Forensic Research.

To analyze the literature on artificial intelligence in forensic research from 2012 to 2022 in the Web of Science Core Collection Database, to explore research hotspots and developmental trends. A total of 736 articles on artificial intelligence in forensic medicine in the Web of Science Core Collection Database from 2012 to 2022 were visualized and analyzed through the literature measuring tool CiteSpace. The authors, institution, country (region), title, journal, keywords, cited references and other information of relevant literatures were analyzed. A total of 736 articles published in 220 journals by 355 authors from 289 institutions in 69 countries (regions) were identified, with the number of articles published showing an increasing trend year by year. Among them, the United States had the highest number of publications and China ranked the second. Academy of Forensic Science had the highest number of publications among the institutions. Forensic Science International, Journal of Forensic Sciences, International Journal of Legal Medicine ranked high in publication and citation frequency. Through the analysis of keywords, it was found that the research hotspots of artificial intelligence in the forensic field mainly focused on the use of artificial intelligence technology for sex and age estimation, cause of death analysis, postmortem interval estimation, individual identification and so on. It is necessary to pay attention to international and institutional cooperation and to strengthen the cross-disciplinary research. Exploring the combination of advanced artificial intelligence technologies with forensic research will be a hotspot and direction for future research.

Research state of the herbal medicine Huangqi (Radix Astragali): A global and bibliometric study.

Huangqi (Radix Astragali) is a natural medicine with a wide range of uses. The research related to Huangqi is getting hotter and the number of publications is gradually increasing. This study aims to explore the current status and emerging trends of Huangqi-related research. Huangqi-related literature was systemically obtained from the Web of Science database. The CiteSpace, VOSviewer, and, R package "Bibliometrix" tools were used to analyze the number of publications, countries, research institutions, journals, authors, keywords, references, and trends. A total of 2255 papers were retrieved for analysis. These papers were written by 11,247 authors from 1927 institutions in 71 countries, published in 570 journals, and cited 73,534 references from 11,553 journals. From 1999 to 2022, the number of publications gradually increased. China was the country with the highest number of publications. The most prolific institution was Shanghai University of Chinese Medicine. Evidence-Based Complementary and Alternative Medicine was the journal publishing the most Huangqi-related literature. Dr Karl Wah Keung Tsim was the authors with the most output publications. The Review, entitle "Review of the Botanical Characteristics, Phytochemistry, and Pharmacology of Astragalus membranaceous (Huangqi)," was the reference being cited most frequently. The major keywords were apoptosis, oxidative stress, and inflammation. Gut microbiota and epithelial-mesenchymal transitions were new research hotspots in recent years. This study used quantitative and visual analysis of Huangqi to provide insights into the research priorities, frontier research hotspots, and future research trends in this field.

Visualizing the bibliometrics of the inflammatory mechanisms in intervertebral disc degeneration

ObjectiveIntervertebral disc degeneration (IVDD) constitutes a crucial pathological foundation for spinal degenerative diseases (SDD) and stands as a primary contributor to both low back pain (LBP) and disability. The progression of IVDD is linked to structural and functional alterations in tissues, where an imbalance in the inflammatory microenvironment can induce extracellular matrix (ECM) degradation, senescence, and apoptosis. This imbalance is a key pathomechanism in the disease's development, gaining considerable attention in recent years. This study aims to conduct a bibliometric analysis of publications pertaining to the inflammatory mechanisms of IVDD to quantitatively assess current research hotspots and directions. MethodsIn this study, we queried the Web of Science Core Collection (WOSCC) database covering the period from January 1, 2001, to November 7, 2023. Content in this area was analyzed and visualized using software such as Citespace, Vosviewer, and the bibliometrix package. ResultsFindings indicate a consistent annual increase in the number of publications, highlighting the widespread attention garnered by research on the inflammatory mechanisms of IVDD. In terms of journal research, Spine emerged with the highest number of publications, along with significantly elevated total citations and average citations compared to other journals. Regarding country analysis, China led in the number of publications, while the USA claimed the highest number of citations and total link strength. Institutional analysis revealed Sun Yat-sen University as having the highest number of publications and total link strength, with Thomas Jefferson University securing the highest total citations. Author analysis identified Ohtori, S. with the highest number of publications, Risbud, M.V. with the highest number of citations, and Inoue, G. with the highest total link strength, all of whom have made significant contributions to the field's development. Citation and co-citation analyses indicated that highly cited documents primarily focused on classical studies exploring inflammatory mechanisms in IVDD pathogenesis. Keyword analysis showcased the ongoing research hotspot as the further investigation of mechanisms and treatment studies. Recent years have seen a shift towards exploring pyroptosis, necrotic apoptosis, autophagy, ferroptosis, oxidative stress, and bacterial infection, among other mechanisms. In terms of treatment, alongside traditional monomer, drug, and compound therapies for IVDD, research is increasingly concentrating on stem cell therapy, exosomes, hydrogels, and scaffolds. ConclusionThis bibliometric analysis of research on inflammatory mechanisms in IVDD provides insights into the current status, hotspots, and potential future trends. These findings can serve as a valuable reference and guide for researchers in the field.

Co-authorship network analysis of North Korean chemistry researchers based on issues of &lt;i&gt;Chemistry and Chemical Engineering&lt;/i&gt; published from 2008 to 2022: a bibliometric study

Purpose: This study conducted a comprehensive analysis of North Korean domestic journals, using scientific quantification methodologies to identify prominent researchers and research areas within the field of chemistry.Methods: Data were collected from the journal Chemistry and Chemical Engineering published in North Korea. Through an analysis of co-authorship relations and literature reviews of papers authored by researchers who were highly influential in research networks, core research areas were identified.Results: The researcher with the highest number of publications in the given period was Yong-Chol Lee, with 31 publications, followed closely by Gyun Kim, who also demonstrated significant research activity. When focusing on the last 5 years, Myeong-Cheol Hong emerged as a prominent figure. Yong-Chol Lee has expertise across diverse fields of chemistry, including fine chemicals, biochemistry, and mineral materials. Gyun Kim, in contrast, is recognized for his in-depth knowledge of organics, enzymes, processes, catalysis, fine chemicals, and industrial chemistry. Myung-Cheol Hong’s research primarily centers around organic chemical synthesis within the fine chemical domain. All three researchers are making substantial contributions to the chemical industry.Conclusion: The findings of this study provide valuable insights into research trends in the field of chemistry in North Korea and contribute to a broader understanding of the discipline’s internal knowledge structure within the global academic community. This research is anticipated to be especially useful for scholars who are analyzing bibliographic information pertaining to North Korea.

Osteotomy for treating knee osteoarthritis from 2012 to 2023: Bibliometric analysis and global trends.

Numerous surgical interventions are available for the treatment of knee osteoarthritis (KOA). In recent years, knee-preserving surgery, specifically osteotomy, has gained significant attention from patients, particularly those who are young and physically active, as it not only effectively alleviates pain but also preserves bone integrity, thereby allowing for potential future joint replacement. This study aims to comprehensively analyze the global application trends of osteotomy for KOA and identify the current research hotspots. We conducted a literature search encompassing English-language studies on osteotomy for KOA published from 2012 to 2023 in the Web of Science Core Collection (WoSCC) database. Bibliometric analysis tools, including VOSviewer, CiteSpace, and R Studio, were employed to analyze global trends and research hotspots. We analyzed 1520 eligible publications, comprising 1350 articles and 170 reviews. The number of articles on osteotomy for KOA has exhibited a consistent upward trend over the past decade. The top 3 contributing countries (South Korea, United States, and China) accounted for 45.98% of all published articles. U.S. scholars exhibited high productivity, prominence, and academic impact in this field. Seoul National University published the most papers on the relationship between osteotomy and KOA, while Sungkyunkwan University had the highest average citation rate. Among authors, Yong Seuk Lee from Korea and Steffen Schroeter from Germany had the highest number of publications and average citation values, respectively. Research interests were clustered into 5 categories: "High tibial osteotomy," "Biomechanics of osteotomy," "Osteotomy combined with cartilage repair techniques," "Postoperative prognosis and outcomes," and "Improvement of surgical techniques." Recent years have witnessed notable rapid progress in the research on osteotomy for KOA. The field is poised for continued growth in terms of academic literature. The United States has emerged as a global leader in knee osteotomy research, while Korea demonstrates considerable potential in this domain. Future research hotspots may encompass high tibial osteotomies, osteotomies combined with cartilage repair techniques, and advancements in surgical techniques for KOA.

Bibliometric analysis of intestinal microbiota and lung diseases.

Increasing evidence suggests a close association between the intestinal microbiome and the respiratory system, drawing attention to studying the gut-lung axis. This research employs bibliometric methods to conduct a visual analysis of literature in the field of intestinal microbiota and lung diseases over the past two decades. It offers scientific foundations for research directions and critical issues in this field. We retrieved all articles on intestinal microbiota and lung diseases from the SCI-Expanded of WoSCC on October 25, 2023. The analysis included original articles and reviews published in English from 2011 to 2023. We utilized Python, VOSviewer, and CiteSpace to analyze the retrieved data visually. A total of 794 publications were analyzed. China ranked first in the number of publications, while the United States had the highest citations and H-index. Jian Wang was the most prolific author. Zhejiang University was the institution with the highest number of publications. Frontiers in Microbiology was the journal with the most publications. Author keywords appearing more than 100 times included "intestinal microbiota/microbiome", "microbiota/microbiome", and "gut-lung axis". The correlation and underlying mechanisms between intestinal microbiota and lung diseases, including asthma, COPD, lung cancer, and respiratory infections, remain hot topics in research. However, understanding the mechanisms involving the gut-lung axis is still in its infancy and requires further elucidation.

Hotspot Analysis and Frontier Exploration of Stem Cell Research in Intervertebral Disc Regeneration and Repair: A Bibliometric and Visualization Study

BackgroundStem cells have shown tremendous potential and vast prospects in the research of intervertebral disc (IVD) regeneration and repair, attracting considerable attention in recent years. In this study, a bibliometric analysis and visualization techniques were employed to probe and analyze the hotspots and frontiers of stem cell research in IVD regeneration and repair, aiming to provide valuable references and insights for further investigations. MethodsThis study utilized the Science Citation Index Expanded (SCI-Expanded) from the Web of Science Core Collection (WoSCC) database to retrieve and extract relevant literature records as research samples. Visual analysis tools such as VOSviewer 1.6.19, CiteSpace 6.2.R4, and bibliometric online analysis platforms were employed to construct scientific knowledge maps, providing a comprehensive and systematic exposition from various perspectives including collaboration networks, co-citation networks, and co-occurrence networks. ResultsA total of 1,075 relevant studies have been published in 303 journals by 4,181 authors from 1,198 institutions across 54 countries/regions. Over the past 20 years, the field of research has witnessed a significant growth in annual publications and citations. China and the United States have emerged as the primary participants and contributors, with the AO Research Institute Davos, Zhejiang University, and Tokai University being the top three leading research institutions. The most productive and highly cited author is Sakai D, who is regarded as a key leader in this research field. The journals with the highest number of publications and citations are Spine and Biomaterials, which are considered to be high-quality and authoritative core journals in this field. The current research focuses primarily on the sources and selection of stem cells, optimization of transplantation strategies, mechanisms of IVD regeneration, and the combined application of stem cells and biomaterials. However, there are still some challenges that need to be addressed, including post-transplantation stability, assessment of regenerative effects, and translation into clinical applications. Future research will concentrate on the diversity of stem cell sources, the application of novel biomaterials, personalized treatments, and the development of gene editing technologies, among other cutting-edge directions. ConclusionThis study utilized bibliometric analysis and visualization techniques to unveil the hotspots and frontiers in the research on stem cells for IVD regeneration and repair. These research findings provide essential guidance and references for further experimental design and clinical applications. However, additional experiments and clinical studies are still needed to address the challenges and difficulties faced in the field of IVD regeneration and repair, thus offering novel strategies and approaches for the treatment of IVD diseases.