When straw pulp papermaking wastewater was treated by the process of coagu-flocculation and nuclear-flocculation, there were still high CODCr. UV254 can reflect organic pollutants and organic pollutants of unsaturated aromatic ring, carbon-carbon double bond. With the decrease of molecular weight of organic pollutants, absorption of ultraviolet light will decrease. Indirectly, it reflectd that the combination process had a good removal effect on high molecular aromatic hydrocarbons difficult to be biodegraded. Meanwhile it can improve the the biodegradability. It used the activated sludge process as subsequent process of coagulation and-flocculation process. The test results showed that the removal rate of CODCr was 24.1%, CODCr was the 88.1mg/L. It reached effluent standard.