A high level of compliance is required to achieve the desired outcomes of treatment among HIV/AIDS patients. There is paucity of information about compliance to preventive strategies in Katsina State of Northern Nigeria. In this study, a questionnaire was developed, validated, and applied to evaluate adherence to prevention strategies in HIV/AIDS patients attending the Federal teaching hospital, Katsina (FTH) in Nigeria using an investigative descriptive study design. The questionnaire was distributed to 303 respondents that were randomly selected out of 1, 250 population of FTH, and all were returned for data analysis. Descriptive statistics, chi-square and t-tests were used to describe the respondent’s demographic information, test the main and sub-hypotheses. Results showed. Results showed significantly higher adherence to prevention strategies among HIV/AIDS patients attending FTH, Katsina (x2 194.55 df 3 p<0.05). HIVAIDS patients attending the FTH, Katsina are subject to guidelines for preventing transmission of HIV/AIDS (x2202.939 df 3 p<0.05). There was also a significant gender-based difference in adherence to prevention strategies among HIV/AIDS patients attending FTH, Katsina (t 25.690 df 301, p value 0.000). Among HIV/AIDS patients attending the FTH, Katsina, there was a significant difference in adherence to prevention strategies based on educational status (t 219.094 df 302, p-value 0.000). Based on location, there was a significant difference in adherence to prevention strategies among HIV/AIDS patients attending the FTH, Katsina (t 23.038 df 301, p-value 0.000). Results from this study shows that HIV/AIDS patients attending Federal Teaching Hospital Katsina significantly adhere to preventive guidelines for curbing the transmission of HIV/AIDS. However to further achieve the desired quality of life improvements for individual subjects and reduce prevalence in the society, concerted efforts are needed to promote compliance to therapy.
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