High-intensity Physical Activity Research Articles

The association between parameters of physical activity and olfactory function-the importance of frequency and moderate intensity.

Overall physical activity (PA) has been linked to decreased olfactory dysfunction and could improve olfactory function. Additionally, decreased olfactory function can contribute to reduced overall PA levels, given its association with neurodegenerative disorders. This study aims to examine the relationship between specific PA parameters (duration, frequency, intensity) and olfactory function in adults. A total of 3,527 participants from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 underwent assessments for weekly PA duration, frequency, and intensity, alongside a smell test (including odors such as chocolate, strawberry, grape, onion, smoke, natural gas, leather, and soap). Correlation analyses and binary logistic regressions using SPSS were used to evaluate associations. The total smell score exhibited small yet significant positive correlations with the duration, frequency, and volume of moderate PA (correlation coefficients ranging between 0.05 and 0.08; all p ≤ 0.05) and frequency of vigorous PA (correlation coefficient of 0.05; p < 0.05). For moderate PA, the duration, frequency, and volume were significantly and positively associated with the ability to correctly detect the smell of grapes while the frequency was significantly and positively associated with the ability to identify smoke and leather odors (odds ratios ranging from 1.01 to 1.07; p < 0.05). For vigorous PA, the frequency of PA was positively associated with the detection of grape smell (odds ratio of 1.05; p < 0.05). Some parameters of an active lifestyle are associated with improved odds of accurately identifying odors by up to 7.4%. Moderate PA duration, frequency, and volume were linked to better olfactory scores, while high-intensity PA had limited associations.

The Effects of Supervision and Activity Status on Physical Activity Participation with Activity Zoned Playgrounds in Elementary-Aged Children

Objective: We compared changes in physical activity (PA) in active and inactive youth during school recess with supervised and unsupervised activity zoned playgrounds (AZP). Methods: We analyzed PA of 143 third-, fourth-, and fifth-graders from 2 elementary institutions using Actigraph-GT3X accelerometers for 4 weeks. We collected baseline data for one week prior to activity zoning. Afterwards, the playgrounds were divided into 6 activity zones for 2 weeks, with activity zones supervised at only one institution. Activity zones were removed, and PA data were collected for one-week post intervention. Results: We saw few differences in PA engagement between the supervision conditions throughout the duration of AZP implementation such that moderate and vigorous PA decreased with supervision (ps &lt; .05). Initial activity status influenced PA engagement with AZP implementation. AZPs significantly reduced vigorous PA engagement in active kids with subsequent increases in light PA engagement, whereas PA engagement remained relatively unchanged among inactive children. Conclusion: Supervising AZP may be detrimental to PA engagement during recess; however, this could be dependent on the reliability of employed supervisors. Additionally, considerable attention is needed with activity development that will appease students of differing activity statuses and prevent decreases in higher intensity PA engagement.

The Effect of Physical Activity Levels on Cognitive Performance: Research in Portuguese Adolescents.

The literature unequivocally acknowledges the numerous health benefits that physical activity (PA) provides. However, in other variables, such as cognitive performance (CP), the PA characteristics required to elicit favorable benefits remain controversial, particularly among adolescents. The aim was to investigate the evolution of CP in adolescents over the school year, as well as the role of regular PA levels. The study included 366 adolescents (boys n = 154), between 12 and 20 years old (15.46 ± 1.63), from middle school (n = 123) and high school (n = 243). CP was assessed through a face-to-face interview employing the Cognitive Telephone Screening Instrument. The variation in CP (∆CP) was determined by the difference between the value of the final assessment (end of the school year) and the initial assessment (start of the school year). PA was assessed using accelerometry (ActiGraph GT3X+). The CP score improved from the initial to the final assessment (37.80 ± 9.26 vs. 40.45 ± 10.05) (t = -6.135; p < 0.001; Glass's Delta = 0.37. Multiple linear regression revealed that age (ß = -0.332; t = -4.255; p < 0.001) and high-intensity PA (ß = 0.283; t = 3.627; p < 0.001) accounted for 17.2% of the variation in ∆CP. CP improved significantly over the school year, emphasizing the significance of age and vigorous PA in ∆CP in adolescents.

Identifying Subgroups of Suicidality Among Adolescents and Influencing Factors Using Latent Class Analysis.

We aimed to classify subgroups of suicidality among adolescents and identify the influencing factors of the classification of these latent classes. Suicidal thought, plans, and attempts as well as the feelings of sadness/hopelessness and loneliness were utilized as indicators to derive the suicidality classes. Additionally, health behaviors, such as dietary habits, physical activity, experiences of violence victimization, sexual activity, and deviant behavior, along with demographic factors, such as sex, school year, grades, and household income, were considered as influencing factors. The analysis utilized data from the 18th Youth Health Behavior Survey (2022) conducted by the Korea Disease Control and Prevention Agency, involving 51,850 middle and high school students. The findings revealed three latent classes of suicidality among adolescents: "active suicidality," "passive suicidality," and "non-suicidality." The influencing factor analysis indicated that all factors, with the exception of high-intensity physical activities, significantly influenced the classification of latent classes of suicidality. Notably, walking exercise and the frequency of exercise during physical education class were found to be factors that differentiated between active and passive suicidality within the suicidality classes. This study employed nationwide data to identify the exhibited suicidality classes among adolescents and tested the influencing factors necessary for predicting such classes. The study's findings offer valuable insights for policy development in suicide prevention and suggest the need for developing customized interventions tailored to each identified class.

What are the important factors influencing the physical activity level of junior high school students: a cross-sectional survey.

Engaging in regular physical activity has been consistently linked to improved physical health and academic performance. Despite its known benefits, there is a concerning trend of decreased physical activity among children globally. The study primarily aims to investigate the level of physical activity among junior high school students in Taiyuan and analyse the main affecting factors from a socio-ecological perspective. A cross-sectional study was conducted, involving 650 junior high school students from 7 schools in Taiyuan, and 648 valid questionnaires were ultimately collected. The data on students' physical activity levels were collected through the Children's Leisure Activities Study Survey Questionnaire, and the data on factors affecting students' physical activity were collected through the Student Perceived Factors Affecting Physical Activity Questionnaire. In this study, students from the 7th, 8th, and 9th grades participated in physical activities, averaging 214.500 min per week in moderate-intensity and 25.000 min in high-intensity activities, cumulatively averaging 280.000 min weekly. Notably, a significant disparity (p = 0.012) was observed in the combined duration of moderate and high-intensity activities, with male students engaging more time compared to their female counterparts (307.500 vs. 255.000 min). This variance extended across different grades, particularly evident in 8th graders who recorded the highest weekly high-intensity activity duration (31.000 min) and overall physical activity time (320.500 min), surpassing the 7th graders(p = 0.007 for high-intensity activities). Furthermore, an exploratory factor analysis of a 32-item questionnaire, designed to identify determinants of physical activity, revealed six principal components. These components were found to positively correlate with both moderate and high-intensity physical activities. Results emphasize that educational institutions and community programs should collaborate to offer engaging weekend physical activity programs. Schools should develop and implement tailored physical education curricula addressing gender and grade differences. Furthermore, schools and local governments should invest in high-quality sports equipment and facilities.

Hubungan Aktivitas Fisik Sedenter dengan Siklus Menstruasi Mahasiswi Fakultas Kedokteran UHAMKA

High intensity physical activity affects Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) while low physical activity that leads to less body movement affects oxidative energy reserves. This study aims to determine the relationship between sedentary physical activity and the menstrual cycle of students of the Faculty of Medicine, Universitas Muhammadiyah Prof. Dr. HAMKA (UHAMKA). The research design was an observational analytic survey with a cross sectional approach. The sample size was determined by the Slovin formula, which was 92 subjects. The results showed that most of the female students (95.65%) with sedentary physical activity, and female students with abnormal menstrual cycle disorders (polymenorrhea) were 31.52% oligomenorrhea 11.96%, hypomenorrhea 64.13%, while hypermenorrhea was only 3.27%. There is no significant relationship between the level of sedentary physical activity with menstrual cycle disorders.

Predictors of physical activity and public safety perception regarding technology adoption for promoting physical activity in Jeddah, Saudi Arabia

BackgroundThis study aims to identify the predictors of levels of physical activity among the residents of Jeddah, Saudi Arabia. Additionally, it seeks to understand the public's safety perception regarding the adoption of technology for promoting physical activity. MethodThis is an analytical cross-sectional study using self-administered web-based survey. A stratified sampling technique was used to select participants from adult population in Jeddah and data collection took place from May 2023 to December 2023. Multivariable logistic regression models were applied to identify predictors of low-intensity (walking steps) and high-intensity physical activities. ResultA total of 462 participated in the study. Gender significantly influenced walking habits, with males more likely to walk than females (AOR = 2.37; 95 % CI: 1.55–3.62; P < 0.001). Smoking status was also a predictor, with smokers more inclined to walk compared to non-smokers (AOR = 2.15; 95 % CI: 1.20–3.82; P = 0.010). High-intensity physical activity strongly correlated with increased walking, especially among those active 3–7 days per week (AOR = 3.03; 95 % CI: 1.91–4.78; P < 0.001). Chronic diseases negatively impacted walking frequency (AOR = 0.57; 95 % CI: 0.34–0.95; P = 0.031). Furthermore, males were likelier to engage in high-intensity activities compared to females (AOR = 1.61; 95 % CI: 1.04–2.50; P = 0.033). Those walking ≥ 10,000 steps weekly were more likely to participate in high-intensity activities (AOR = 3.07; 95 % CI: 1.95–4.82; P < 0.001). Excellent self-rated health was associated with higher participation in such activities (AOR = 2.00; 95 % CI: 1.30–3.06; P = 0.002). Most respondents (84.9 %) felt safe on public walkways, and 78.1 % indicated safety perceptions influenced their walkway use. Technology use was divided, with about half (49.1 %) using apps for tracking physical activity. The majority (90.9 %) supported adding motivational features to the 'Sehhaty' app, and 73.6 % favored financial rewards for walking. However, only 45.5 % believed that public walkways are designed to encourage walking. ConclusionThe study highlights significant predictors of physical activity among general population in Jeddah. The study also revealed the impact of safety perceptions and technology use on physical activity, with strong support for motivational features in health apps. However, there is a need for improved design of public walkways to encourage walking.

Association between physical activity and allostatic load among pregnant women.

Allostatic load (AL) in pregnant women is associated with maternal and infant health outcomes. Whether physical activity (PA) is a modifiable factor associated with AL during pregnancy is unknown. In this cross-sectional study, including 725 pregnant women in 3 different trimesters, 8 biomarkers were included, and the high-risk quartile approach based on sample distribution was used to construct AL index (ALI). ALI <2 was defined as a low level and ≥2 as a high level. Student's t-test or Mann-Whitney U test and chi-squared test or Fisher exact test were used to compare differences in AL with different demographic characteristics among pregnant women. The relationship between PA and AL in pregnant women was analyzed using a binary logistic regression model. The results show that the detection rate of high-risk AL during pregnancy was 47.3%. In the adjusted model, sufficient PA was related to a lower AL than insufficient PA (OR=.693, 95%CI:.494,.971; p=.033). Compared with low- and high-intensity PAs, moderate-intensity PA was associated with lower AL (OR=.645, 95%CI:.447,.930; p=.019). The results suggest that PA is a modifiable factor related to AL, and intervention is recommended to be carried out in the first trimester to prevent the increased likelihood of high AL as pregnancy progresses. In addition, health care personnel should encourage pregnant women to participate in PA, especially moderate-intensity PA, in order to obtain lower AL and promote maternal and child health.

Evaluation of a High Intensity Interval Training (HIIT) Program for Military Personnel Receiving Inpatient Treatment for a Substance Use Disorder

This study aimed to evaluate a high intensity interval training (HIIT) program delivered in an inpatient treatment setting serving military personnel. This recreational therapy (RT) program assessed the impact of a single session (60-minute) HIIT program on participant affect and state-anxiety. Using a single-group pretest-posttest design, 58 data sets were collected from participants (N = 20). Results indicated an increase in positive affect (z = -.6.52, p &lt; .001), a decrease in negative affect (z = -2.64, p &lt; .01), and a significant reduction in anxiety, t (57) = 1.99, p = .05 following the intervention. The program also resulted in a significant elevation in heart rate, t (57) = -25.89, p &lt; .001 with most participants reaching moderate to high intensity physical activity levels. On a scale of 1–10, participants rated their likelihood of participating in HIIT post-discharge at 6.28 (SD = 2.43). Additional qualitative data provides valuable insight on the perceived benefits to participants and offers suggestions for future program development and research in this area.

Association between intensity of physical activity and cognitive function in hypertensive patients: a case–control study

Previous studies have shown that a higher intensity of physical activity (PA) is associated with a lower risk of cognitive impairment (CI), whereas hypertension is associated with higher CI. However, there are few studies on the association between PA intensity and cognitive function in hypertensive patients. This study investigated the association between PA intensity and cognitive function in hypertensive patients. A total of 2035 hypertensive patients were included in this study, including 407 hypertensive patients with CI and 1628 hypertensive patients with normal cognitive function matched 1:4 by age and sex. The International Physical Activity Questionnaire-Long Form and the Mini-mental State Examination were used to evaluate PA intensity, total metabolic equivalents, and cognitive function in patients with hypertension. Multivariate logistic regression was used to analyze the correlation between PA intensity and CI in hypertensive patients. The Spearman correlation coefficient was used to analyze the correlation between PA intensity and the total score of each component of the MMSE and the correlation between PA total metabolic equivalents and cardiac structure in hypertensive patients. After adjusting for all confounding factors, PA intensity was negatively associated with CI in hypertensive patients (OR = 0.608, 95% CI: 0.447–0.776, P < 0.001), and this association was also observed in hypertensive patients with education level of primary school and below and junior high school and above (OR = 0.732, 95% CI: 0.539–0.995, P = 0.047; OR = 0.412, 95% CI: 0.272–0.626, P < 0.001). The intensity of PA in hypertensive patients was positively correlated with orientation (r = 0.125, P < 0.001), memory (r = 0.052, P = 0.020), attention and numeracy (r = 0.151, P < 0.001), recall ability (r = 0.110, P < 0.001), and language ability (r = 0.144, P < 0.001). PA total metabolic equivalents in hypertensive patients were negatively correlated with RVEDD and LAD (r = − 0.048, P = 0.030; r = − 0.051, P = 0.020) and uncorrelated with LVEDD (r = 0.026, P = 0.233). Higher PA intensity reduced the incidence of CI in hypertensive patients. Therefore, hypertensive patients were advised to moderate their PA according to their circumstances.

Relationship between 24-h activity behavior and body fat percentage in preschool children: based on compositional data and isotemporal substitution analysis

ObjectiveThis study aims to elucidate the dose‒response relationship between 24-h activity behaviors and body fat percentage (BFP) in Chinese preschool children using a compositional isotemporal substitution model (ISM).MethodsIn a cross-sectional design, 881 children aged 3–6 from urban and rural areas of Jiangxi Province were sampled. Activity behaviors, including sedentary behavior (SB), low-intensity physical activity (LPA), and moderate- to high-intensity physical activity (MVPA), were measured using accelerometers. Sleep patterns were assessed through questionnaires, and BFP was determined by bioelectrical impedance analysis (BIA). The study employed compositional data analysis (CoDA) and ISM to estimate the impact of reallocating durations of different activity behaviors on BFP.ResultsHigher BFP was found in urban vs. rural children, decreasing with age. Overweight and obesity rates were 10.6% and 7.6%, respectively, above national averages. MVPA and LPA were negatively correlated with BFP, while SB was positively correlated.A 30-min MVPA reduction significantly increased zBFR, particularly in overweight children. Gender-specific nuances revealed that boys' MVPA negatively influenced zBFP (β = -0.155), P < 0.05), while girls' SB positively impacted zBFP (β = 0.636, P < 0.01). Isotemporal simulations emphasized amplified effects in overweight children, with boys' zBFR rising rapidly when MVPA was substituted and girls displaying a notable substitution effect between SB and LPA.ConclusionBFP is closely linked to 24-h activity behaviors, notably in overweight and obese preschoolers. ISM identified MVPA as a critical influencer, with a 30-min reduction substantially increasing BFP. Gender disparities were evident, implicating MVPA in boys and LPA and SB in girls.

Age-specific association of physical activity on visceral obesity: Cross-sectional study

AimsObesity is a chronic disease that needs to be managed worldwide. High-intensity physical activity has a positive effect on the improvement and prevention of metabolic diseases. The purpose of this study was to investigate the age-specific association of physical activity on abdominal and visceral obesity. MethodsThe study involved 456 health check-up participants who underwent abdominal computed tomography scans for the assessment of visceral fat area from January 2017 to December 2017. Physical activity levels were categorized as none-to-low-intensity or moderate-to-vigorous-intensity based on the International Physical Activity Questionnaire. Logistic regression analysis, adjusted for covariates, assessed the association of physical activity with abdominal and visceral obesity across 10-year age intervals. ResultsThe moderate-to-vigorous physical activity group showed 56.5% visceral obesity, while the none-to-low-intensity physical activity group had 63.2%. Most age groups exhibited no significant differences in abdominal or visceral obesity according to physical activity. However, the 50 to 59 age group demonstrated a noteworthy association between visceral obesity and none-to-low-intensity physical activity (odds ratio 3.79, 95% confidence interval 1.12–12.84). ConclusionsThis study highlights a distinct age-related response to physical activity, emphasizing the 50 to 59 age group's significant association between visceral obesity and none-to-low-intensity physical activity.

Associations between monitor-independent movement summary (MIMS) and fall risk appraisal combining fear of falling and physiological fall risk in community-dwelling older adults.

Introduction: Fall Risk Appraisal (FRA), a process that integrates perceived and objective fall risk measures, serves as a crucial component for understanding the incongruence between fear of falling (FOF) and physiological fall risk in older adults. Despite its importance, scant research has been undertaken to investigate how habitual physical activity (PA) levels, quantified in Monitor-Independent Movement Summary (MIMS), vary across FRA categories. MIMS is a device-independent acceleration summary metric that helps standardize data analysis across studies by accounting for discrepancies in raw data among research-grade and consumer devices. Objective: This cross-sectional study explores the associations between MIMS (volume and intensity) and FRA in a sample of older adults in the United States. Methods: We assessed FOF (Short Falls Efficacy Scale-International), physiological fall risk (balance: BTrackS Balance, leg strength: 30-s sit-to-stand test) and 7-day free-living PA (ActiGraph GT9X) in 178 community-dwelling older adults. PA volume was summarized as average daily MIMS (MIMS/day). PA intensity was calculated as peak 30-min MIMS (average of highest 30 non-consecutive MIMS minutes/day), representing a PA index of higher-intensity epochs. FRA categorized participants into following four groups: Rational (low FOF-low physiological fall risk), Irrational (high FOF-low physiological fall risk), Incongruent (low FOF-high physiological fall risk) and Congruent (high FOF-high physiological fall risk). Results: Compared to rational group, average MIMS/day and peak 30-min MIMS were, respectively, 15.8% (p = .025) and 14.0% (p = .004) lower in irrational group, and 16.6% (p = .013) and 17.5% (p < .001) lower in congruent group. No significant differences were detected between incongruent and rational groups. Multiple regression analyses showed that, after adjusting for age, gender, and BMI (reference: rational), only irrational FRA was significantly associated with lower PA volume (β = -1,452.8 MIMS/day, p = .034); whereas irrational and congruent FRAs were significantly associated with lower "peak PA intensity" (irrational: β = -5.40 MIMS/day, p = .007; congruent: β = -5.43 MIMS/day, p = .004). Conclusion: These findings highlight that FOF is a significant barrier for older adults to participate in high-intensity PA, regardless of their balance and strength. Therefore, PA programs for older adults should develop tailored intervention strategies (cognitive reframing, balance and strength exercises, or both) based on an individual's FOF and physiological fall risk.

Per- and polyfluoroalkyl substances and bone mineral content in early adolescence: Modification by diet and physical activity

BackgroundPer- and polyfluoroalkyl substance (PFAS) exposures may negatively impact bone mineral accrual, but little is known about potential mitigators of this relation. We assessed whether associations of PFAS and their mixture with bone mineral content (BMC) in adolescence were modified by diet and physical activity. MethodsWe included 197 adolescents enrolled in a prospective pregnancy and birth cohort in Cincinnati, Ohio (2003–2006). At age 12 years, we collected serum for PFAS measurements and used dual-energy x-ray absorptiometry to measure BMC. We calculated dietary calcium intake and Health Eating Index (HEI) scores from repeated 24-h dietary recalls, physical activity scores using the Physical Activity Questionnaire for Older Children (PAQ-C), and average moderate to vigorous physical activity (MVPA) based on accelerometry. We estimated covariate-adjusted differences in BMC z-scores per interquartile range (IQR) increase of individual PFAS concentrations using linear regression and per simultaneous IQR increase in all four PFAS using g-computation. We evaluated effect measure modification (EMM) using interaction terms between each modifier and PFAS. ResultsHigher serum perfluorooctanoic acid, perfluorooctanesulfonic acid, and perfluorononanoic acid concentrations and the PFAS mixture were associated with lower BMC z-scores. An IQR increase in all PFAS was associated with a 0.27 (−0.54, 0.01) lower distal radius BMC z-score. Associations with lower BMC were generally stronger among adolescents classified as < median for calcium intake, HEI scores, or MVPA compared to those ≥ median. The difference in distal radius BMC z-score per IQR increase in all PFAS was −0.38 (−0.72, −0.04) for those with <median calcium intake versus −0.03 (−0.48, 0.35) for ≥ median (EMM p-value = 0.16); the corresponding differences by MVPA were −0.42 (−0.76, −0.07) for < median and −0.05 (−0.42, 0.32) for ≥ median (EMM p-value = 0.13). ConclusionHealthy, calcium-rich diets and higher intensity physical activity may mitigate the adverse impact of PFAS on adolescent bone health.

Role of Different Forms and Intensities of Physical Activity in Prevention of Dementia

IntroductionDementia is one of the greatest health challenges worldwide. According to the World Health Organisation (WHO) factsheet, currently more than 55 million people worldwide have dementia, with over 60% living in low- and middle-income countries. Every year, there are nearly 10 million new cases of dementia. WHO Global Status Report 2021 estimated growth of 139 million people with dementia by 2050. The estimated total global cost of dementia is likely to surpass US$ 2.8 trillion by 2030. As one grows older, the risk of developing dementia, particularly Alzheimer’s Disease, progressively increases. The Lancet Commission Reports 2017 and 2020 on dementia prevention, intervention, and care identified 12 modifiable risk factors, including physical inactivity, obesity, midlife hypertension, and diabetes. Addressing these lifestyle factors may significantly reduce the risk of dementia and its progression. While no curative or disease-modifying treatment is available for dementia at his stage, addressing modifiable risk factors may have a preventive role in reducing the risk of dementia.ObjectivesThe objective of the literature review is to explore current evidence on Physical Activity (PA) in reducing the risk of developing dementia and its progression. The focus is also to see the association of different forms and intensities of PA and their intensities, including aerobic, strength-based, and leisure, with the risk and progression of dementia.MethodsNarrative reviewResultsResults from the reviewed studies showed that PA was found to be associated with a reduced risk of dementia, particularly Alzheimer’s Disease. Studies comparing different intensities of PA indicate though all levels of PA decrease the risk of dementia, there is a linear relationship between the higher intensity PA and the increased beneficial effect in terms of reduced risk of dementia. Leisure-time PA also has a protective role against dementia in longitudinal studies. There is more consistent evidence in favour of aerobic PA; however, it has a ceiling effect. The combination of aerobic and strength-based experience provides optimum beneficial effects. The elderly population who started physical activity in their 80s experienced the beneficial effects of PA in reducing the risk of dementia. There is mixed evidence of the protective effect of PA on the population who have already developed cognitive impairment or have genetic vulnerabilities. The author will also include the results of any relevant study published by 31 March 2024.ConclusionsThe details of the literature results and conclusions will be discussed at the conference.Disclosure of InterestI. Singh Consultant of: The author declare that the review was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., R. Chandra: None Declared

A Field Study to Assess Physical Activity Levels During Weekdays Among Students in the First Cycle and its Relationship with Lower Limb Muscle Strength

This study aimed to assess physical activity levels during 3 school days among first cycle students and its relationship with lower limb muscle strength. Twenty-eight students from the Governor of Muscat were participated in this study, (age: 11.8±0.3 years, height: 9.0±148 cm, mass Body: 14.5±34.8 kg, BMI: 5.3±19.2 kg.m-2 To assess physical activity levels, the ActiGraph GT3X device was used for 3 school days during the week (from 8:00 am to 12:00 pm, daily). All participating performed two tests of lower limb muscle strength (CMJ - FCM). Study results showed that the average physical activity levels of students during 3 school days were (455.9± 56.7minutes) and (26.3±6.6 minutes) for both sedentary physical behavior (SPA) and high-intensity physical activity (VPA), respectively. The results also revealed that the level of moderate and vigorous physical activity level (MVPA) during 3 days of school reached (67.9 ±17.01minutes), which is approximately (22.6 minutes per day), meaning that there was a noticeable decrease in the levels of physical activity practiced during school days (3 days). per week for first cycle students. The results also showed that there was no relationship between all physical activity levels (SPA, LPA, MPA, VPA, MVPA) and lower limb muscle strength tests (CMJ - FCM) among the students (0.05&lt;p).

The Correlation between the Level of Physical Activity and the Incidence of Breast Cancer in RSUD Dr. Soetomo Surabaya

Breast cancer is one of the most common cancers worldwide. This study aims to investigate and analyze the relationship between the level of physical activity and the occurrence of breast cancer at Dr. Soetomo Hospital Surabaya. The research method employed in this study is correlation analysis. The sample population was obtained from the Cancer Service Development Center (PPLK) at Dr. Soetomo Hospital Surabaya. The results of this study indicate that the majority of the 53 research subjects suffering from breast cancer had low-intensity physical activity since childhood to adolescence, with 41.5% of the total subjects (22 patients). In contrast, only 24.5% (13 patients) and 34% (18 patients) had moderate and high-intensity physical activity, respectively. Statistical analysis using Microsoft Excel version 2019 and SPSS showed that the calculated Chi-square value was greater than the tabulated Chi-square value, thus rejecting the null hypothesis (H0). This indicates a significant relationship between the intensity of physical activity during childhood to adolescence and the occurrence of breast cancer in the research subjects. This study implicates the importance of awareness regarding the significance of physical activity in maintaining breast health, especially from a young age. The practical implication of this research is the necessity of a preventive approach to breast cancer involving the promotion of a healthy lifestyle and regular physical activity, particularly during childhood and adolescence.

Immunosuppressant medication behaviours in solid organ transplant recipients: a cross-sectional study from south-central China during COVID-19 reopening period

ObjectiveMedication non-adherence to immunosuppressants threatens allograft survival and function maintenance among solid organ transplant (SOT) recipients. This study aimed to investigate the prevalence of immunosuppressant medication non-adherence and associated factors...

Зв’язок способу життя і ментального здоров’я дітей міста Києва на другому році війни

The aim of the study was to research changes in the daily routine and learning of schoolchildren during the war and their association with mental health. Materials and methods: A study of daily routines and mental health of schoolchildren in Kyiv was conducted using an online questionnaire. Informed consent was obtained from parents. For analyzing 1417 questionnaires were selected (743 boys, 674 girls). The study of responses to the questionnaires made it possible to determine the weekly duration of physical activity (PA) of light (LPA) and moderate and high-intensity physical activity (MVPA), the duration of sedentary activity (SB) and sleep, as well as to determine the gradation of anxiety-depressive indicators and signs of post-traumatic stress disorder (PTSD). The formats of the learning process were evaluated (full-time, distance, mixed). The data obtained were also compared with the data at the beginning of the full-scale invasion. Statistical methods of data obtained were used. Results: The study showed that during the war, Kyiv schoolchildren’s daily routine and level of physical activity changed. In the spring of 2023, (47.0±1.4)% of Kyiv schoolchildren had full-time learning, (19.3±1.1)% - in distance learning, (32.9±1.3_% - in mixed learning, in contrast to 2022, when children learned mainly in a distance format. In 2023, there was a 6.4% decrease in sleep duration compared to 2022. Additionally, there was a 19.2% increase in total physical activity due to LPA, while conversely, there was a 17.7% decrease in MVPA. In 2022, 23.1% of school-age children had the optimal level of MVPA (60 min/day), while in 2023, this percentage decreased to 11.3% (p&lt;0.001). The proportion of children with anxiety, depression indicators and PTSD in 2023 was 10.5%, 26.4%, and 13.9%, respectively. In the presence of signs of depression and/or anxiety, schoolchildren demonstrated a decrease in all types of physical activity, a reduction in sleep duration, and, conversely, an increase of SB. Conclusions: Further research is needed to study the impact of lifestyle on the mental health of schoolchildren during the war, given the decreased duration of MVPA in Kyiv schoolchildren against the background of increased level of depression indicators. This will enable the identification of at-risk groups and the implementation of comprehensive measures to assist children in adapting during humanitarian emergencies.

Fractional amplitude of low-frequency fluctuations associated with μ-opioid and dopamine receptor distributions in the central nervous system after high-intensity exercise bouts.

Dopaminergic, opiod and endocannabinoid neurotransmission are thought to play an important role in the neurobiology of acute exercise and, in particular, in mediating positive affective responses and reward processes. Recent evidence indicates that changes in fractional amplitude of low-frequency fluctuations (zfALFF) in resting-state functional MRI (rs-fMRI) may reflect changes in specific neurotransmitter systems as tested by means of spatial correlation analyses. Here, we investigated this relationship at different exercise intensities in twenty young healthy trained athletes performing low-intensity (LIIE), high-intensity (HIIE) interval exercises, and a control condition on three separate days. Positive And Negative Affect Schedule (PANAS) scores and rs-fMRI were acquired before and after each of the three experimental conditions. Respective zfALFF changes were analyzed using repeated measures ANOVAs. We examined the spatial correspondence of changes in zfALFF before and after training with the available neurotransmitter maps across all voxels and additionally, hypothesis-driven, for neurotransmitter maps implicated in the neurobiology of exercise (dopaminergic, opiodic and endocannabinoid) in specific brain networks associated with "reward" and "emotion." Elevated PANAS Positive Affect was observed after LIIE and HIIE but not after the control condition. HIIE compared to the control condition resulted in differential zfALFF decreases in precuneus, temporo-occipital, midcingulate and frontal regions, thalamus, and cerebellum, whereas differential zfALFF increases were identified in hypothalamus, pituitary, and periaqueductal gray. The spatial alteration patterns in zfALFF during HIIE were positively associated with dopaminergic and μ-opioidergic receptor distributions within the 'reward' network. These findings provide new insight into the neurobiology of exercise supporting the importance of reward-related neurotransmission at least during high-intensity physical activity.