High Intensity Conditions Research Articles

The Effects of a Cycling Warm-up Including High-Intensity Heavy-Resistance Conditioning Contractions on Subsequent 4-km Time Trial Performance.

Chorley, A and Lamb, KL. The effects of a cycling warm-up including high-intensity heavy-resistance conditioning contractions on subsequent 4-km time trial performance. J Strength Cond Res 33(1): 57-65, 2019-Previous exercise has been shown to improve subsequent performance through different mechanisms. Sport-specific conditioning contractions can be used to exploit the "post-activation potentiation" (PAP) phenomenon to enhance performance although this has rarely been investigated in short endurance events. The aim of this study was to compare a cycling warm-up with PAP-inducing conditioning contractions (CW) with a moderate-intensity warm-up (MW) on performance and physiological outcomes of a 4-km time trial. Ten well-trained male endurance cyclists ((Equation is included in full-text article.)max 65.3 ± 5.6 ml·kg·min) performed two 4-km cycling time trials after a 5-minute recovery after a warm-up at 60% of (Equation is included in full-text article.)max for 6.5 minutes (MW), and a warm-up with conditioning contractions (CW) consisting of 5 minutes at 60% of (Equation is included in full-text article.)max then 3 × 10-second at 70% of peak power interspersed with a 30-second recovery. Blood lactate concentrations were measured before and after time trial. Expired gases were analyzed along with time, power output (PO), and peak forces over each 500 m split. After CW, mean completion time was reduced (1.7 ± 3.5 seconds p > 0.05), PO increased (5.1 ± 10.5 W p > 0.05) as did peak force per pedal stroke (5.7 ± 11 N p > 0.05) when compared with MW. (Equation is included in full-text article.)increased (1.4 ± 1.6 ml·kg·min p ≤ 0.05) after CW, whereas respiratory exchange ratio (RER) decreased (0.05 ± 0.02 p ≤ 0.05). Physiological and performance differences after CW were greatest over the first 1,500 m of the trials. The results suggest that a PAP-inducing warm-up alters (Equation is included in full-text article.)kinetics and can lead to performance improvements in short endurance cycling but work and recovery durations should be optimized for each athlete.

The Experimental Effects of Acute Exercise Intensity on Episodic Memory and Working Memory Function

The purpose of this study was to evaluate the potential intensity-dependent effects of acute exercise on episodic memory and working memory capacity. A counterbalanced, randomized controlled, within-subject design was employed (N=20; Mage=20.8 yrs). The three counterbalanced visits included a control visit, moderate-intensity exercise (40% of HRR) and high-intensity exercise (70% of HRR). Episodic memory was assessed from a word-list task, including an immediate and delayed (20-min delay) assessment. Working memory capacity was assessed from the Brown-Peterson task. Immediate episodic memory recall was similar across the three conditions (8.5-8.7 words). However, for the 20-min delay period, the high-intensity exercise condition had a higher word recall score than the two other conditions (5.7 vs. 4.9). For the working memory task, there was a statistically significant main effect for condition (F=4.3, P=0.02, η2p=0.18), main effect for delay period (F=30.6, P

한 종합병원 간호사들의 노동시간 유형에 대한 평가

Objective: The aim of this study is to investigate the working time patterns including length, shift type, shift intensity, and special aspects of working hours for hospital nurses.BR Background: Working time patterns, such as long working hours and shift work with night shift, are important public health issue. However, most of the previous studies were based on the self-report data, and only a few studies have attempted to comprehensively estimate the working time pattern by considering various aspects of work.BR Method: The work schedule of a total of 1,254 nurses who worked at a general hospital in 2017, were analyzed using the electronic data recorded in the computerized system. We examined 15 potentially health-relevant working time factors for nurses, categorized under four main domain heading of: (1) Time of the day, (2) length of working hours, (3) shift intensity, and (4) special aspects of working hours.BR Results: Among a total of 1,254 nurses, most nurses (82.4%) were work with 3-shift type. 2-shfit nurses had 32.3±24.3% of the experience of more than 40 hours a week, followed by 3-shift nurses (22.5±18.7), and daytime nurses (14.7±11.6). But the experience of three consecutive night shift spells were higher among 3-shift (4.1±6.2 times) than 2-shift nurses (0.3±0.5), and the experience of working on weekend or legal holiday was higher in 3-shift nurses (42.9±23.2%) than 2-shift (36.6±17.9) and daytime (12.7±11.3) nurses, while the number of having more than three consecutive free days was lowest in 3-shift nurses (8.9±6.0 times) compared with 2-shift (21.3±12.6) and daytime nurses (10.3±5.9).BR Conclusion: 3-shift nurses had less long working hours, but high shift intensity and disadvantageous social working conditions than 2-shfit nurses, and 2-shift nurses worked with night shift and had long working hours, high shift intensity, but advantageous in social aspects than daytime nurses.BR Application: The results of this study might help to improve understanding of working time pattern in hospital nurses, and lay an important foundation for further research on health of nurses in Korea.

Combined effects of unsteady wake and free-stream turbulence on turbine blade film cooling with laid-back fan-shaped holes using PSP technique

Detailed film cooling effectiveness distribution for a gas turbine blade under the effects of unsteady wakes and oncoming free-stream turbulence intensities was obtained using pressure sensitive paint (PSP) technique. Tests were performed on a linear cascade at Reynolds number of 3.85 × 105 based on the blade chord at cascade exit. Upstream unsteady wakes were simulated using a spoke-wheel type wake generator. The test blade has three rows of compound angled cylindrical film holes at the leading edge, five rows of laid-back fan-shaped holes on the pressure surface and three rows of laid-back fan-shaped holes on the suction surface. The wake Strouhal number was varied from 0 to 0.36 and three mass flux ratios were determined. The oncoming free-stream turbulence intensities are 2.7% and 26.9%, respectively. Results show that the effect of the mass flux ratio on the film cooling effectiveness decreases under the high turbulence intensity and unsteady wake conditions. In most regions of the blade surface, the film cooling effectiveness decreases with the increase of wake Strouhal number, and the free-stream turbulence superimposed on the unsteady wake reduces the film cooling effectiveness further. The effect of the unsteady wake decreases under the high free-stream turbulence conditions.

Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease

Notch signals drive pathogenic T cell alloreactivity in mouse models of allogeneic bone marrow transplantation (allo-BMT) leading to lethal graft-versus-host disease (GVHD). In a mouse model of MHC-mismatched allo-BMT with high intensity whole body conditioning (11 Gy), residual recipient or donor hematopoietic cells were dispensable sources of Notch signals to drive T cell alloreactivity. Instead, abrogating the expression of Delta-like1 (Dll1) and Delta-like4 (Dll4) Notch ligands in Ccl19-Cre+ secondary lymphoid organ (SLO) fibroblastic stromal cells protected mice from GVHD (Chung et al., JCI 2017). In this study we sought to 1) understand the expression and regulation of Notch ligands in fibroblastic stromal cells during allo-BMT; 2) test whether fibroblastic stromal cells are still critical sources of Notch signals in models of allotransplantation with reduced or no conditioning (when other radiation-sensitive sources of Notch ligands are better preserved); and 3) assess whether SLO fibroblastic stromal also present alloantigens to T cells during GVHD.To characterize stromal sources of Notch ligands early after allo-BMT, we combined a Ccl19-Cre transgene with a ROSA26-YFP Cre-activated allele in Dll4-mCherry BAC reporter mice. We observed combined Ccl19-Cre activity and Dll4-mCherry reporter expression in CD157hi fibroblastic reticular cells, MAdCAM1+ marginal reticular cells, CD21+ follicular dendritic cells, and a subset of MAdCAM1+ lymphatic endothelial cells. 12 hours after high intensity conditioning and allo-BMT, Dll4 mRNA and cell surface expression increased in fibroblastic but not in hematopoietic or endothelial cellular compartments. Dll4 upregulation required transfer of alloreactive T cells and was potentiated by the intensity of myeloablative conditioning, suggesting that fibroblastic stromal cells have increased availability of Notch ligands to drive GVHD after high-intensity conditioning.To assess the functional impact of conditioning on the cellular sources of Notch ligands, we studied a parent-to-F1 allo-BMT model in which recipients are tolerant to donor-derived T cells, and the conditioning intensity can be titrated (C57BL/6 [H-2b] or BALB/c [H-2d] into BALB/c x C57BL/6 F1 [H-2d/b]). Cell-specific genetic loss of function systems combining floxed alleles for Dll1 and Dll4 with Ccl19-Cre+ and Mx-Cre+ transgenes allowed conditional deletion in SLO fibroblastic stromal cells or hematopoietic cells, respectively. Across all conditioning intensities tested, upregulation of core-2 O-glycosylation machinery in alloreactive T cells was critically regulated by Notch signals. Thus, induction of the core-2 glycoform of CD43 could be used as a sensitive surrogate readout of Notch signals received by alloreactive T cells. In models of allotransplantation with high-intensity (11 Gy), low-intensity (3 Gy), and no conditioning, fibroblastic stromal cells remained essential and hematopoietic cells were dispensable as sources of Notch signals driving both T cell core-2 O-glycosylation and lethal alloimmunity.Because previous studies indicated that non-hematopoietic cells can serve as antigen-presenting cells in CD4+ T cell mediated GVHD, we tested if fibroblastic stromal cells could present MHC class II alloantigens in addition to Notch ligands. We used Ccl19-Cre+ crossed to mice with a floxed I-A allele to delete the cell-intrinsic ability of fibroblastic stromal cells to present MHC class II alloantigens. In multiple models of high-intensity conditioned CD4+ T cell mediated GVHD (BALB/c [H-2d] into BALB/c x C57BL/6 F1 [H-2d/b] and TEa TCR Tg into BALB/c x C57BL/6 F1 [H-2d/b]), fibroblastic stromal cells were dispensable as sources of alloantigen to drive T cell alloreactivity and lethal GVHD. Together, these results indicate that across varying conditioning intensities, specialized subsets of SLO fibroblastic stromal cells critically regulate T cell alloreactivity through presentation of Notch ligands independently of antigen presentation. Selective targeting of Delta-like Notch ligand expression on SLO fibroblastic cells may prevent T cell immunopathology while preserving other beneficial antigen-dependent T cell responses after both high-intensity conditioned allo-BMT and allotransplantation with reduced intensity conditioning. DisclosuresBlazar:Kadmon Corporation, LLC: Consultancy, Research Funding. Siebel:Genentech: Employment.

Partition-coordinated control of soil and water loss for chestnut forests in the Yanshan Mountain Region, China

Soil erosion from chestnut forests is one of the most important factors causing land degradation in the Yanshan Mountain Region. A 2-year field study was done to compare the effects on erosion of a control plot (CP), a repaired and maintained horizontal ditch built with an engineering baffle every 6 m (MP 1), and a repaired and maintained horizontal ditch built with an engineering baffle every 8 m (MP 2). The results showed that the slope runoff of chestnut forests was influenced by rainfall characteristic factors. No single rainfall characteristic factor showed dominance for hill slope runoff. The runoff reduction effect of the partition-coordinated erosion control measures (MP 1 and MP 2) was substantial for chestnut forests under high rainfall intensity conditions. However, the runoff reduction efficiency was higher under the conditions of heavy rainfall and low average rainfall intensity than for storms with higher intensity and lower total rainfall. The reduction effect of the partition-coordinated erosion control measures on the runoff and sediment yield of chestnut forest slopes was MP 2 > MP 1 > CP. The runoff reduction rate and erosion reduction rate of MP 2 reached 61.70% and 97.41%, respectively, and that for MP 1 was 54.15% and 85.31%, respectively. Therefore, after a comprehensive comparison, MP 2 was determined to be more effective for soil erosion control for a sloping chestnut forest.

Carbon storage implications of active management in mature Pseudotsuga menziesii forests of western Oregon

Mature stands, mid-successional communities in which large live trees are the dominant structural feature, are a major component of forested landscapes across North America. Despite this prominence at regional scales, mature stands have rarely been the focus of research on forest carbon dynamics. We utilized an observational study design to (i) examine the medium-term impact of active management on carbon storage in live and dead vegetation in mature Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco)–dominated stands in western Oregon, and (ii) provide baseline estimates of total non-soil carbon storage during the mature phase of stand development for this forest type. Stands aged 106–193 years at the time of sampling were selected to represent a gradient in harvest intensity, from passive (reserve-based) management, to low-intensity (commercial thinning) and high-intensity (regeneration harvest with structural retention) active management. Active management treatments were implemented following the onset of maturity in stands with no prior management history, and sampling was conducted an average of 38 years and 22 years following treatment (mean for thinned and retention harvest conditions, respectively). Total non-soil carbon storage was significantly greater in stands managed using a reserve-based approach (mean of 575 Mg C ha−1) than those subject to retention harvest (mean 257 Mg C ha−1) 17 to –34 years previously, but was not different from stands managed over extended rotations with commercial thinning (mean 546 Mg C ha−1). A similar trend was evident for carbon storage in live overstory trees, which were also the dominant component of total non-soil carbon in all management conditions. Dead wood pools varied greatly among stands, but estimates did not indicate any systematic differences in carbon storage in dead wood between management conditions. Our results suggest that shifting from passive management to a high-intensity harvest regime in mature Douglas-fir stands will entail substantial reductions in carbon storage. By contrast, managing stands over extended rotations with light thinning may enable the provision of wood products while maintaining relatively high carbon storage in the forest ecosystem. In absolute terms, mean carbon storage across our full sample of unmanaged, low-intensity and high-intensity harvest conditions exceeded previously reported values from inventories of mature plots across a similarly broad range of site conditions, but remains below the potential upper bounds to carbon storage in Douglas-fir-dominated forests. However, total aboveground carbon stocks in excess of 700 Mg ha−1 in individual mature stands in our dataset implies that, under certain conditions, forest biomass approaches its maximum by the close of the mature phase of stand development in Douglas-fir-dominated forests.

Reduced Graphene Oxide Nanostructures by Light: Going Beyond the Diffraction Limit

Graphene oxide (GO) offers excellent possibilities that are recently demonstrated in many applications ranging from biological sensors to optoelectronic devices. The process of thermal annealing aids in removing the oxygen-containing groups in GO, making GO more graphene-like, or the so-called reduced graphene oxide (rGO). Thermal reduction can also be achieved by intense light. Here, we demonstrate a scalable, inexpensive, and environmentally friendly method to pattern graphene oxide films beyond the diffraction limit of light using a conventional laser. We show that contrary to previous reports, non-linear effects that occur under high intensity conditions of laser irradiation allow the fabrication of highly conductive carbon nanowires with dimensions much smaller than the laser spot size. The potential of this method is illustrated by the fabrication of several devices on flexible and transparent substrates, including hybrid plasmonic/rGO sensors.

Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity

AbstractIn this study, we sought to identify specific individual high-intensity or reduced-intensity conditioning regimens with the best relapse-free survival (RFS) rather than the global high- vs reduced-intensity regimen comparison. Patients (median age, 58 years) with acute myeloid leukemia (AML; n = 1258), who were in first or subsequent remission, or with MDS (n = 951) who had refractory anemia with unilineage or multilineage dysplasia, 5q− syndrome, or refractory anemia with excess blasts received nonirradiation-containing regimens and were transplanted between 2009 and 2014 in the United States. Three-year RFS with high-intensity busulfan/cyclophosphamide (Bu4/Cy; 44%) was comparable to conditioning with high-intensity fludarabine/busulfan (Flu/Bu4; 44%), reduced-intensity fludarabine/melphalan (Flu/Mel; 52%; P = .53), and Flu/Mel + anti-thymocyte globulin (ATG; 44%; P = .38). RFS was lower with reduced-intensity Flu/Bu2 + ATG (31%; P = .0006). RFS was also lower with high-intensity Flu/Bu4 + ATG (38%; P = .05) and reduced-intensity Flu/Bu2 (38%; P = .02), although the difference did not reach the level of significance set for these analysis. RFS with Flu/Mel was superior to RFS with Flu/Bu2 (P = .01) and Flu/Bu2 + ATG (P = .0006). The 3-year incidence of relapse was 22% with Flu/Mel compared with 46% with Flu/Bu2 and 56% with Flu/Bu2 + ATG. With only a modest reduction in nonrelapse mortality with the Flu/Bu2 regimens, the higher relapse incidence resulted in lower RFS. The data support optimal RFS with Bu4/Cy, Flu/Bu4, and Flu/Mel regimens for AML in remission or MDS. The low relapse rate with reduced-intensity Flu/Mel resulted in RFS comparable to that after the higher-intensity regimens.

Predator odour but not TMT induces 22-kHz ultrasonic vocalizations in rats that lead to defensive behaviours in conspecifics upon replay

Predator odours induce defensive behaviour in prey animals such as rats. The present study investigated (1) whether laboratory rats exposed to predator odours emit 22-kHz calls which may have an alarming function and (2) whether playback of such calls induces behavioural changes in conspecifics. For this, Sprague-Dawley rats were exposed to samples of fox and lion urine, as well as to the synthetic predator odour TMT. Despite that all odours induced defensive behaviour, only predator urine samples but not TMT were able to induce 22-kHz calls in a few rats. In a second experiment, naive rats were exposed to playback presentations of the 22-kHz calls recorded in the first experiment, as well as to phase-scrambled and frequency-shifted control stimuli. Low intensity playback presentations led to a reduction of locomotor activity during the presentation of the 22-kHz calls but not of the control stimuli. This effect was less specific under high intensity conditions. Taken together the present findings show that natural predator odours are able to induce emission of 22-kHz calls in rats and support the hypothesis that these calls have an alarming function.

Site-directed mutagenesis of two amino acid residues in cytochrome b559 α subunit that interact with a phosphatidylglycerol molecule (PG772) induces quinone-dependent inhibition of photosystem II activity

X-ray crystallographic analysis (1.9-Å resolution) of the cyanobacterial photosystem II (PSII) dimer showed the presence of five phosphatidylglycerol (PG) molecules per reaction center. One of the PG molecules, PG772, is located in the vicinity of the QB-binding site. To investigate the role of PG772 in PSII, we performed site-directed mutagenesis in the cytochrome (Cyt) b559 α subunit of Synechocystis sp. PCC 6803 to change two amino acids, Thr-5 and Ser-11, which interact with PG772. The photosynthetic activity of intact cells was slightly lower in all mutants than that of cells in the control strain; however, the oxygen-evolving PSII activity was decreased markedly in cells of mutants, as measured using artificial quinones (such as p-benzoquinone). Furthermore, electron transport from QA to QB was inhibited in mutants incubated with quinones, particularly under high-intensity light conditions. Lipid analysis of purified PSII showed approximately one PG molecule per reaction center, presumably PG772, was lost in the PSII dimer from the T5A and S11A mutants compared with that in the PSII dimer from the control strain. In addition, protein analysis of monomer and dimer showed decreased levels of PsbV and PsbU extrinsic proteins in the PSII monomer purified from T5A and S11A mutants. These results suggest that site-directed mutagenesis of Thr-5 and Ser-11, which presumably causes the loss of PG772, induces quinone-dependent inhibition of PSII activity under high-intensity light conditions and destabilizes the binding of extrinsic proteins to PSII.

Effect of light intensity and nutrients supply on microalgae cultivated in urban wastewater: Biomass production, lipids accumulation and settleability characteristics

Microalgae cultivation systems fed with wastewater as source of nutrients represents the principal sustainable condition to produce microalgal biomass to be converted conveniently to biofuels. In order to optimize microalgae growth and their lipid content, the effect of light intensity and nutrients load in real wastewater was investigated through batch microalgal cultivation tests. A microalgal polyculture was used as inoculum and grown for 10 days in batch at different conditions of light intensity (i.e. 20, 50 and 100 μmol s−1m−2) and nutrients concentration in wastewater. Experimental results showed that biomass productivity decreased for rich nutrients conditions and increased for high light intensities. The highest lipid mass content (29%) was found for high light intensity condition (100 μmol s−1m−2). Furthermore, microalgae settleability tests, conducted at the end of the cultivation time, resulted in the highest biomass recovery efficiency (72%) for low light intensity and nutrients supply conditions.

Railway track inspection and maintenance priorities due to dynamic coupling effects of dipped rails and differential track settlements

Abstract Each year, there can be three to six millions of service train axles running over an open plain track. In fact, these trains could impose a variety of dynamic loading conditions depending on the wheel and rail maintenance levels. Inevitably, the risk of high-intensity dynamic loading conditions by wheel-rail interactions due to wheel or rail irregularity cannot be disregarded. Imperfection of rail tracks could lead directly to the exceedance of permissible stress of a track component and later amplify rapid track deterioration rates causing cracking in sleepers and failure of track substructure. Practical railway track irregularities can be typically classified into short wave length (high frequency) and long wave length (low frequency) defects, of which previous researchers had studied each in isolation. This paper is the first to study the influence on railway track inspection and maintenance priorities caused by the coupling of wave lengths between dipped rail joint and differential track settlements. To study the dynamic coupling effects, P1 and P2 forces are evaluated at the track irregularity together with rail/sleeper contact force, ballast pressure and bending moments of sleepers using dynamic multi-body simulation approach. It is found that some patterns of coupling irregularity could cause a significant reduction in dynamic impact factors whilst some are associated with an increase in the wheel/rail impact force. The insight has then been integrated to establish track performance indicators that are paramount for prioritising track inspection and maintenance.

Differential effects of intensity and response preparation components of acoustic warning signals

Abstract It is known that the increase of intensity on a warning signal (WS) usually decreases reaction times to targets and occasionally is accompanied by a startle reflex reaction that influences the speediness of response execution. In a simple detection task (Experiment 1), a detection task with catch trials (Experiment 2) and a Go-NoGo discrimination task (Experiment 3), we studied the relationship between response preparation and alerting mechanisms operating upon the presentation of warning signals. A WS was presented either synchronously with the target (simultaneous condition) or 1400 ms before it (delayed condition). In all three experiments, the intensity of the WS and the simultaneity between WS and target were orthogonally manipulated. Results confirmed shorter reaction times by increasing the WS intensity. In Experiment 1, all conditions presented a clear acoustic intensity effect. In Experiment 2 we observed shorter reaction times in higher intensity conditions but only when the WS and the target were presented simultaneously. In Experiment 3, the intensity effect was observed only when the WS preceded the target. In all experiments, trials where the WS triggered a startle reflex showed a systematic increase in reaction time, which was independent of response preparation and task demands. In general, our findings suggest that response preparation modulates the alerting mechanisms, as a function of task set, but not the startle reflex. The dissociation between intensity, response preparation and startle supports the interdependence between these mechanisms elicited by the presentation of warning signals.

Removal behavior of slime from pentlandite surfaces and its effect on flotation

Jinchuan is the largest nickel producer in China. The separation of pentlandite from serpentine gangue is difficult in this flowsheet because serpentine slime can attach to the valuable minerals as a slime coating. To solve this problem, the removal of different sized serpentine slimes from sulfide surfaces and its effect on flotation were studied using flotation experiments, particle size analysis, and X-ray diffraction. The results illustrated that the slime particles attached to coarse particle surfaces after grinding and depressed pentlandite flotation. The slimes comprised mainly MgO minerals. High-intensity conditioning could be used to remove the coarser slimes, while sodium hexametaphosphate could be used to remove the fine slimes. These two methods were used in combination in the flotation of Jinchuan nickel sulfide ore and the metallurgical performance was significantly improved: nickel recovery increased from 82.97% to 86.27% and the MgO content decreased to 6.22%.

MODERATE INTENSITY IS A BETTER STIMULUS TO INDUCE QUADRIPECS FEMORIS POWER IN ELDERLY ADULTS

ABSTRACT Introduction: The best strategy for improving knee extensor power, a major functional capacity indicator in older adults, is power training. Nonetheless, the training intensity required to induce optimal gains is yet to be found. Objective: Our purpose was to compare knee extensor peak power responses between low, moderate, and high intensity load conditions (30%, 50% and 70% of 1RM). Methods: Thirteen sedentary elderly women performed six knee extensions in each load condition, calculating knee extensor mechanical work/power output and knee extension peak angular velocity. Results: No difference in peak power was found between the high (207.0 ± 68.1 W) and moderate (206.1 ± 71.6 W) load conditions (p = 0.994), and both had higher values (p ≤0.004) than the low intensity condition (135.6 ± 56.3 W). Conclusion: Moderate load at 50% of 1RM appears to be the preferred strategy for inducing knee extensor power output because in contrast with the high intensity condition, the moderate load yielded higher angular peak velocity, which is also a functional indicator. Level of Evidence ll; Therapeutic studies - Investigating treatment results.

Numerical simulation of movement of both rock mass and surface under thick loose layer high-intensity mining condition

Numerical simulation of movement of both rock mass and surface under thick loose layer high-intensity mining condition

Roller massage decreases spinal excitability to the soleus.

Roller massage (RM) interventions have shown acute increases in range of motion (ROM) and pain pressure threshold (PPT). It is unclear whether the RM-induced increases can be attributed to changes in neural or muscle responses. The purpose of this study was to evaluate the effect of altered afferent input via application of RM on spinal excitability, as measured with the Hoffmann (H-) reflex. A randomized within-subjects design was used. Three 30-s bouts of RM were implemented on a rested, nonexercised, injury-free muscle with 30 s of rest between bouts. The researcher applied RM to the plantar flexors at three intensities of pain: high, moderate, and sham. Measures included normalized M-wave and H-reflex peak-to-peak amplitudes before, during, and up to 3 min postintervention. M-wave and H-reflex measures were highly reliable. RM resulted in significant decreases in soleus H-reflex amplitudes. High-intensity, moderate-intensity, and sham conditions decreased soleus H-reflex amplitudes by 58%, 43%, and 19%, respectively. H-reflexes induced with high-intensity rolling discomfort or pain were significantly lower than moderate and sham conditions. The effects were transient in nature, with an immediate return to baseline following RM. This is the first evidence of RM-induced modulation of spinal excitability. The intensity-dependent response observed indicates that rolling pressure or pain perception may play a role in modulation of the inhibition. Roller massage-induced neural modulation of spinal excitability may explain previously reported increases in ROM and PPT. NEW & NOTEWORTHY Recent evidence indicates that the benefits of foam rolling and roller massage are primarily accrued through neural mechanisms. The present study attempts to determine the neuromuscular response to roller massage interventions. We provide strong evidence of roller massage-induced neural modulation of spinal excitability to the soleus. It is plausible that reflex inhibition may explain subsequent increases in pain pressure threshold.

Đặc điểm hình thái, giải phẫu thích nghi của một số loài thực vật sống tại núi đá ven biển xã Nhơn Lý, thành phố Quy Nhơn, tỉnh Bình Định

Coastal region has extremely harsh conditions for living. Plants changed the morphological and anatomical features for adapting to this particular environment. The plants, which live in coastal region of Nhon Ly, Quy Nhon city, Binh Dinh province, have adaptive traits with strong winds, high lighting intensity and drought conditions. The study was carried out on the morphological and anatomical features of 5 plant species of undershrub and grass in Magnoliopsida. The methods used include morphological comparison, microsurgery, double staining, microscope measurement and microscope photograph of leaf, stem and root. The results showed that the leaf palisade tissue developed (92.70% of leaf thickness), leaf upper epidermis is covered by thick hair layer or thick cuticle (4.55% of leaf thickness) which helped plant adapt to bright sunlight and high temperature; the short stem or growing close to the ground, the secondary xylem developed in stem (up to 59.21% of the stem radius) and in root (up to 78.34% of the root radius); xylem and phloem fibers much located in stem for adapting to strong winds; the high numbers of root xylem (183.17 ± 6.15 vessels/mm2 ) for adapting to drought.

Response of leaf traits of common plants in alpine meadow to plateau pika disturbance

Leaf traits have been proven to reflect the adaptation of individual plants to disturbance environments in a grassland ecosystem. A field survey was conducted to investigate the effects of the disturbance intensity of plateau pika on the leaf traits of a dominant (Kobresia pygmaea) and two common plants (Elymus nutans and Anemone rivularis var. flore-minore) in an alpine meadow. This study indicated that the plateau pika disturbance enables the individuals of three plants to exhibit respective plasticity because the three plants had different leaf indices (LI) as the disturbance intensity increased. K. pygmaea, E. nutans and A. rivularis var. flore-minore had high specific leaf area (SLA), leaf dry mass content (LDMC), and leaf nitrogen content (LNC) at relatively low, moderate, and high disturbance intensities of plateau pika, respectively. K. pygmaea, E. nutans and A. rivularis var. flore-minore suffered low nutrient stress at low, moderate and high disturbance intensities due to high N : P at corresponding disturbance intensities. These results indicated that K. pygmaea, E. nutans and A. rivularis var. flore-minore grew well at relatively low, moderate, and high disturbance intensity conditions, respectively, which contributed to the improvement of alpine meadows with a higher proportion of E. nutans at a moderate disturbance intensity or the deterioration of alpine meadows with a higher proportion of A. rivularis var. flore-minore at a high disturbance intensity. Our findings suggest that leaf traits are effective tools to explain how small burrowing herbivore disturbances often lead to the improvement or deterioration of alpine meadows under different disturbance intensities.