High Incidence Of Hepatitis Research Articles

Reduced Hepatitis After Blood Transfusion by Australia Antigen Testing of Donor Blood.

Excerpt A means was sought to reduce the high incidence of hepatitis after blood transfusion in patients at Philadelphia General Hospital (PGH). This was prompted by the finding that the incidence ...

Hepatitis Among Missionaries in Ethiopia and Sudan

Among a group of 178 adult missionaries in Ethiopia, icteric hepatitis occurred at an annual rate of 5.5%. In another group of 57 adults in Ethiopia, and among 66 adults in Sudan, the annual rates were 3.9% and 2.0%, respectively. The incidence among children tended to be lower. The incidence of hepatitis continued at a high level for many years. As a prophylactic, γ-globulin would have been required for many years, not only for the first few. Not more than 55% appeared likely to develop immunity because of inapparent (anicteric) infection. The rate of second bouts of icteric hepatitis was about one fifth the rate for first attacks. The presence of a cold season in the climate may have contributed to the high incidence of hepatitis in Ethiopia, as compared to Sudan.

Postnecrotic cirrhosis without antecedent acute liver disease.

Postnecrotic cirrhosis is considered, in the United States, almost always to be a residual of infectious or homologous serum hepatitis, although in occasional instances, exposure to toxic chemicals may be blamed.¹In the tropics, malnutrition is believed to be an important etiologic factor. Whatever the basic cause, all appear to have in common the ability to produce the diffuse hepatocellular necrosis required in the pathogenesis of postnecrotic cirrhosis. During and since World War II, there has been a high incidence of hepatitis throughout the world. This has stimulated great interest in the possible residuals of that disease. In our experience and in that of others,^2,3there also has recently been an increase in the frequency of postnecrotic cirrhosis, and it is natural to associate the two conditions. There have been, however, a number of patients in whom postnecrotic cirrhosis appears to have developed<i>de novo</i>.^4,5Not only