Background: Analogue computer techniques were applied to measure power delivered and assess electrophysical factors influencing broad based polypectomy. Methods: Total energy, cutting time and tissue effect were measured during snare polypectomy cuts using polyp models formed in porcine gastric tissue as well as 7 and 11mm polyp stalks fashioned from post mortem porcine muscle. Constant forces were applied to close the snares. The high frequency generator used was the Erbotom ICC 200 on it s CUT(1-4), ENDOCUT(a sequential blend of CUT 1-4 and Soft COAG) and COAG(Soft and Forced) settings. Results: FCOAG waveforms required more power to initiate polyp model cutting than ENDOCUT or CUT on all settings (p<0.05) and required more snare closing force. Increasing polyp stalk size increased wire contact-length and linearly the energy required. On CUT, ENDOCUT and FCOAG roughly the same energy was required for polypectomy if the force closing the snare was increased during FCOAG for the 7mm polyp stalks and gastric polyps. Interestingly, the 11mm polyp stalks required more power on FCOAG to cut than the higher CUT and ENDOCUT settings (p<0.05).The lower settings for CUT and ENDOCUT didn t cut well on the larger polyp models. The tissue effect on CUT and ENDOCUT was significantly less than forced COAG(but still adequate) despite increasing snare force(p<0.001). Time for polypectomy decreased significantly from FCOAG to ENDOCUT(p<0.001) and from ENDOCUT to CUT(p<0.001). Thin wire snares cut at lower power than thick (p<0.05), but often the tissue effect was poor. Increasing force exerted on snare increased cutting rate. Cutting efficiency varied widely. Conclusions: These experiments measured the effect of waveform, power-setting, polyp stalk - size and snare force on initiation, cutting efficiency and tissue effect of endoscopic snare polypectomy. Broad based polyps may be more safely resected using blended waveforms than coagulation alone. Background: Analogue computer techniques were applied to measure power delivered and assess electrophysical factors influencing broad based polypectomy. Methods: Total energy, cutting time and tissue effect were measured during snare polypectomy cuts using polyp models formed in porcine gastric tissue as well as 7 and 11mm polyp stalks fashioned from post mortem porcine muscle. Constant forces were applied to close the snares. The high frequency generator used was the Erbotom ICC 200 on it s CUT(1-4), ENDOCUT(a sequential blend of CUT 1-4 and Soft COAG) and COAG(Soft and Forced) settings. Results: FCOAG waveforms required more power to initiate polyp model cutting than ENDOCUT or CUT on all settings (p<0.05) and required more snare closing force. Increasing polyp stalk size increased wire contact-length and linearly the energy required. On CUT, ENDOCUT and FCOAG roughly the same energy was required for polypectomy if the force closing the snare was increased during FCOAG for the 7mm polyp stalks and gastric polyps. Interestingly, the 11mm polyp stalks required more power on FCOAG to cut than the higher CUT and ENDOCUT settings (p<0.05).The lower settings for CUT and ENDOCUT didn t cut well on the larger polyp models. The tissue effect on CUT and ENDOCUT was significantly less than forced COAG(but still adequate) despite increasing snare force(p<0.001). Time for polypectomy decreased significantly from FCOAG to ENDOCUT(p<0.001) and from ENDOCUT to CUT(p<0.001). Thin wire snares cut at lower power than thick (p<0.05), but often the tissue effect was poor. Increasing force exerted on snare increased cutting rate. Cutting efficiency varied widely. Conclusions: These experiments measured the effect of waveform, power-setting, polyp stalk - size and snare force on initiation, cutting efficiency and tissue effect of endoscopic snare polypectomy. Broad based polyps may be more safely resected using blended waveforms than coagulation alone.