Background: Four methods are available for detecting suspected schistosomiasis. These include microscopic, serological, molecular, and imaging techniques. Objectives: In this study, the author describes diagnosis tools of schistosomiasis. These include microscopic, serological, molecular, and imaging techniques Methodology: The author searched Google, ScienceDirect, and PubMed Database at National Center for Biotechnology Information (NCBI) published between 2009 and 2020. Articles were unrestricted open access, articles with permissions from Elsevier if required, and in English. Other relevant publication were also included. Results: All diagnosis tools are beneficial for detecting schistosomiasis in all Schistosoma species. Diagnosis tools may include microscopic, serological, molecular, and imaging techniques. These methods can include such as the Kato-Katz, Schsitosoma japonicum 16-fraction antigen, electrochemical immunosensor array (Sj16FA-ECISA), loop-mediated isothermal amplification (LAMP), and magnetic resonance imaging (MRI). Microscopic approaches of diagnosis are for the high endemic areas. Serological and molecular approaches are for low endemic areas in particular. Molecular approaches could be beneficial for both endemic areas and low endemic areas. Imaging techniques consists of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI). All are beneficial to assess schistsomiasis accurately. Conclusion: All diagnosis tools were beneficial for detecting schistsomiasis. Microscopic tools are for high endemic areas. Both molecular and serological tests are for low-endemic areas. Imaging techniques are for making imaging for damage to organs such as the liver due to schistsome infections. These tools can include such as the Kato Katz, HAMA-EITB, LAMP, and MRI. Diagnosis tools have important role in eliminating schistos