Efficiency during operation is besides reliability and cost effective production one of the most important demands on machines and components. Especially within the automotive sector, components need to fulfill these requirements. Since the demands for high efficiency and reliability cannot be met solely by typical base materials such as case hardened steels, physical vapor deposition (PVD) coatings for the application on highly loaded components gain increasing importance. A possible approach to reduce friction and wear in tribological systems are triboactive and tribocatalytic coatings which contain triboactive elements such as Mo and Cu which can interact with lubricants and lead to the formation of friction and wear reducing tribochemical reaction layers. Besides coating development, also the design of lubricants is in the focus of research activities to reach friction reductions. Therefore, increasing interest gains towards low viscosity lubricants e.g. for e-mobility applications, since reduced friction would lead to extended range.Within the current work, triboactive (Cr,Al,Mo)N and (Cr,Al,Cu)N, (Cr,Al,Mo,Cu)N coatings were deposited by means of cathodic arc evaporation (Arc PVD) in an industrial scale coating unit. The contents of Mo and Cu were varied. As substrate material the case hardened gear steel AISI 5115 (16MnCr5E) was used. The effects of Mo and Cu on the phase formation were investigated by means of X-ray diffraction (XRD). Analysis of the mechanical properties was conducted by nanoindentation (NI) measurements. Tribological behavior of the coatings was analyzed under continuous sliding conditions in pin on disc (PoD) tribometer under minimum quantity lubrication with lubricant amounts of V = 0.05 ml at a temperature T = 80 °C. As lubricants, a low viscosity lubrication oil and a conventional mineral oil were used. Both lubricants contained sulphur and phosphor (S-P) or sulphur (S) additives. In order to investigate the influence of the counter part material on the tribological behavior, inert Si3N4 balls and 100Cr6 steel balls were used. Initial Hertzian contact pressures were set to pH ≈ 1400 MPa and pH ≈ 1600 MPa, respectively. Wear was analyzed by confocal laserscanning microscopy (CLSM). Tribochemical interactions between the coatings and lubricants were studied by Raman spectroscopy. It was found that tribochemical interactions between Mo of the coatings and S of the lubricants can lead to the in situ formation of MoS2 in tribological contact.