To the Editor.— The criteria for the administration of rabies vaccine after animal bites have been outlined by the Public Health Service. 1 However, the situation becomes somewhat more complex when the victim is a hemophiliac since the expense and possible risks involved in maintaining even minimal hemostatic levels during the course of rabies prophylaxis becomes prohibitive. This report describes the successful use of rabies vaccine in a moderately severe hemophiliac without replacement therapy, and suggests that future patients with this unusual combination of events can be managed in a similar fashion. Report of a Case.— A 25-year-old classic hemophiliac (factor VIII deficiency) was seen after an attack by a stray dog. The patient had a factor VIII level of 2 units/100 ml and had a history of spontaneous hemarthrosis. The wounds were treated with appropriate local therapy and factor VIII concentrate calculated to bring the patient level to 30