Objective: To determinate that male fertility influenced by testicular volumein albino rats. Study Design: Experimental. Place and Duration of study: Institute of BasicMedical Sciences, Dow University of Health Sciences, Karachi, 10 months (November 2009to August 2010). Methodology: Sixty four adult albino rats were obtained from animal houseJinnah Postgraduate Medical Centre for the study and divided into 2 groups. Group A receivedinjection normal saline 1 cc intraperitoneally (IP) daily for 8 weeks. Group B received leadchloride in a dose of 10 mg/kg body weight IP daily. On the day of completion of treatmentthe animals were sacrificed testes along with epididymis removed and place in Petri dish. Thelength, breath and width of testes were measured with help of vernier caliper. The spermatozoawere obtained from cauda epididymis. Results: The mean ± SEM of volume testes in groupA and B after eight week of treatment were 0.77142 ± 0.04778 cm3 & 0.11768 ± 0.01673 cm3respectively. The volume of testes of group B was significantly decreased as compare to groupB (P = 0.000). Mean ±. The mean ± SEM number of sperm cells million / ml in groups A andB after eight week of treatment was 7.65 ± 186706.553 & 1.84 ± 132792.770 respectively.Number of sperms in group B were significantly decreased as compared to group A (P =0.000). Conclusion: There was relationship between volume of testes and male fertility.
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