Helical strakes as a classic passive control method for vortex-induced vibration (VIV), have been extensively studied, but wake-induced galloping (WIG) control of three tandem cylinders has received no previous attention. The current wind tunnel experimental study tries to fill this gap in the context of mechanical science. WIG of three tandem cylinders considering different structures of helical strakes is modeled and investigated. Helical strakes with varying heights G, pitches P, and cross-sectional shapes (square “S”, involute “I”, and D-shaped “D”) are first designed. Wind tunnel tests are conducted to experimentally study the dynamics responses of tandem cylinders (m*ξ = 0.09) at different spacings, and three vibration modes are obtained. This study delves into the characterization and quantification of the impact of various parameters of helical strakes on WIG of three tandem cylinders. These aspects, scarcely addressed in existing research, are thoroughly explored through statistical analysis, focusing on vibration amplitude, vibration frequency, and wavelet analysis. It is found that helical strakes can effectively suppress the multi-frequency vibration instability of bare cylinders. For wind speeds below 6 m/s, the "S" helical strakes achieves a vibration suppression efficiency of up to 665 %; Three-dimensional computational fluid dynamics (3D-CFD) demonstrate the coupling effect in the flow field, revealing that the "S" helical strakes has a greater impact on boundary layer formation than the "D" helical strakes; Reducing the pitch of the helical strakes can enhance the disturbance ability of the spanwise position, thereby increasing its suppression effect. This work improves vibration reduction and sheds light on how the helical strakes' cross-section controls vibrations in the tandem cylinders.