Freeze-thaw cycles are recognized as one of the key triggers for some major landslides in cold regions around the world. Though the effects of freeze-thaw cycles on the rock strength degradation have been studied extensively, little effort has been made to qualitatively evaluate how it contributes to the evolution from a stable rock slope to a large-scale mass movement. In this study, we use a discrete element-based numerical model to simulate the entire process of the initiation of landslide under the action of freeze-thaw cycles in a slope with randomly distributed initial cracks. The main goal of this work is to quantitatively describe the landslide evolution process regarding the slope displacement, crack propagation, stress chain and load-bearing structure. Our results show the essence of the displacement evolution of a landslide subjected to freeze-thaw cycles; namely frost heave pressure induces the generation of new cracks, leading to the failure and reconstruction of the load-bearing structure of the slope. Deep-seated landslides can occur when the slope is crossed by a fault; otherwise, the slope is prone to surface erosion or shallow landslides.