PurposeThe aim of this study was to determine the central corneal thickness (CCT) of healthy Saudi children aged 7-12 years and investigate variations in CCT according to age and sex.Patients and methodsIn this prospective study, one eye was analyzed from each of 412 healthy children. The CCT was measured using a noncontact Nidek CEM 530 specular microscope. A regression analysis was carried out to determine the relationship between CCT and age, and an unpaired t-test was used to compare findings between the sexes; CCT percentiles were then calculated for each age.ResultsThe median CCT among all participants was 576 μm. Regression analysis detected a strong positive correlation between CCT and age (r = 0.64, P < 0.0001), and CCT was found to increase by 8.26 μm each year. The mean CCT of boys was 0.45 μm thicker than that of girls, but this difference was not statistically significant (P = 0.83).ConclusionThe CCT increased with age from 7 to 12 years, and there was no statistically significant difference in the CCT of boys and girls.