Healthy Exercise Research Articles

Exploring health behaviors and the role of pet dogs in households with autistic children: the DANE study.

Autism spectrum disorder (ASD) often presents a unique set of risk factors that impact healthy eating and physical activity. Animal-assisted interventions (AAI) are a promising approach for autistic children. There is growing evidence for the positive impact of AAIs on self-regulation, which is necessary for initiating and maintaining behavioral changes. Pet dogs offer several potential advantages as a vehicle for an AAI focused on health behaviors. However, little is known about the experiences of autistic children and their families with respect to dog ownership and the mechanisms through which such an AAI might operate. We conducted interviews with ten parent-child dyads to explore the role of pet dogs in the lives and lifestyle habits of families with an autistic child. Interview guides were designed to explore the relationship between the autistic child and the pet dog and the role of the dog in family life; attitudes and practices related to physical activity and nutrition; and thoughts about intervention strategies. We used a directed qualitative content analysis approach for analysis. Themes indicate a strong bond between the child and the dog, the child's enjoyment in caring for their dog, and successful integration of dogs within family routines. In contrast, minor themes emerged around the challenges that owning a pet dog posed for families with an autistic child. In terms of nutrition and physical activity, a major theme among children was that healthy eating and exercise were important for both them and their dogs. However, minor themes suggest challenges with healthy eating and exercise and room for improvement for these behaviors. Parents held favorable views toward an intervention that would incorporate the family dog to teach children about nutrition and physical activity, although they expressed some concerns about feasibility. This exploratory work suggests that AAIs to improve nutrition and physical activity could build on the strong bond that children have with their pet dogs, but should consider the specific needs of each family, including the needs of the pet dog.

Weight increase in people with cystic fibrosis on CFTR modulator therapy is mainly due to increase in fat mass.

Background: Ivacaftor, the first CFTR modulator drug, leads to significant long-term improvement in lung function and weight gain. The mechanism as well as the long-term impact of ivacaftor on weight, resting energy expenditure (REE) and body composition remains to be explored. Methods: This prospective observational study included 18 people with CF (pwCF) (age: median (range) 20 (6-58) years) carrying at least one CFTR gating mutation commencing ivacaftor. Assessments of body composition, REE and laboratory investigations were performed at baseline and 6, 12 and 24 months after treatment initiation. Results: Treatment with ivacaftor was associated with a significantly positive change in BMI z-score at 24 months. Fat mass (mean (95% CL) of 6.5kg (4.0; 9.0) from baseline, p = 0.0001), but not fat-free mass changed under ivacaftor treatment. There was a significant positive correlation between weight and fat mass change. Overall, there was no significant change in measured REE from baseline (mean (95% CL) of 108kcal/d (-12; 228), p = 0.07) in our cohort. Pancreatic function and other nutritional markers did not change with treatment, with the exception of an increase in serum vitamin A levels (p = 0.006). Conclusion: The weight gain observed in ivacaftor treated pwCF is predominantly secondary to increases in fat mass warranting early counseling of people starting on CFTR-modulating treatment with respect to healthy diet and physical exercise.

Doctors’ recommendations and healthy lifestyle behaviors among individuals with hypertension in Brazil

Little is known about whether doctors’ recommendations encourage healthy behaviors among individuals with hypertension in Brazil. This study examined the biological, social, and health factors related to doctor’s recommendations and the associations between doctor’s recommendations and healthy behaviors. The sample consisted of individuals with hypertension (N = 18,260) from Brazil’s 2019 National Health Survey. The outcomes examined included smoking, drinking, diet, salt intake, physical activity, and doctor visits. Study findings indicated that more than 80% of people with hypertension in Brazil received doctors’ recommendations to adhere to medical care and engage in healthy behaviors. Those who received recommendations were more likely to practice healthy eating and exercise regularly but also to be obese/overweight, smoke, and drink excessively. Nonetheless, the findings concerning diet and exercise suggest the value of doctors’ recommendations for individuals with hypertension in Brazil.

Evolved Eugenics and Reinforcement of "Othering": Renewed Ethico-Legal Perspectives of Genome Editing in Reproduction.

This article extends an exploration into renewed ethico-legal perspectives of genome editing technologies, examined from an evolved conceptualization of eugenics in contemporary human reproduction. Whilst the ethico-legal conundrums presented by genome-editing technologies in various aspects of modern medicine have thus far inspired a comprehensive trove of academic scholarship-and notwithstanding the World Health Organization's (WHO) publication of guidelines on human genome editing in 2021-the legislative landscape for these technologies remain relatively unchanged. Accordingly, this paper presents the unresolved problematic questions that still require significant reflection. First, the paper highlights these questions, which primarily center around the tension between reproductive autonomy and the legal governance of reproductive/genome editing technologies by a democratic state. Secondly, the paper interrogates the evolved conceptualization of eugenics, exercised on the part of prospective parents as part of reproductive autonomy. By this, the paper predicates that it indirectly reinforces societal and systemic problems of discrimination and "othering", increasing reproductive inequalities in excluded communities. Thirdly, the paper attempts to offer narratives of intersectionality as a facilitating tool in a continuing dialogue to build belonging, foster a healthy and balanced exercise of reproductive autonomy, and increase reproductive equalities.

Barriers and confidence among colorectal and prostate cancer survivors participating in two behavioral intervention studies.

Exercise and healthy diet are key components of cancer survivorship. We sought to explore perceived barriers to engaging in healthy diet and exercise, and whether these barriers change throughout remote-based behavioral interventions. Smart Pace (SP) and Prostate 8 (P8) were two 12-week pilot randomized controlled trials (RCTs) among 42 colorectal cancer (CRC) survivors and 76 prostate cancer (PC) survivors, respectively, that encouraged participants to implement exercise (both) and healthy diet (P8 only) through text messaging and wearable fitness monitors; P8 also included web materials. Participants completed surveys on perceived barriers and confidence in their ability to implement healthy behaviors at enrollment and 12 weeks; P8 also included a 52-week assessment. At enrollment, CRC survivors commonly reported a lack of discipline/willpower (36%), time (33%), and energy (31%); PC survivors often reported a lack of knowledge about healthy dietary behaviors (26%). Not having anyone with whom to exercise with was a common barrier among both groups (21% in CRC, 20% in PC). Among the intervention groups in both studies, various enrollment barriers (overall, functional/psychological disability, aversiveness, excuses, and inconveniences) were associated with change in behavior over time. Among CRC and PC survivors, there are multiple potential barriers related to motivation, time, social support, and lack of knowledge, that can be addressed and overcome to improve healthy behaviors. Tailoring lifestyle interventions to participants' individual barriers and confidence is needed to promote and sustain behavior change long-term.

Familial predisposition to diabetes: How do parents and offsprings perceive the risk?

Introduction: Familial predisposition to diabetes is an important determinant for its occurrence in the immediate descendants. Perception of this risk provides an opportunity to educate the family to adopt health-promoting behaviors and thereby delay or prevent new cases among children. Methods: A questionnaire-based cross-sectional study was conducted among parents with diabetes to assess their awareness on the risk of developing diabetes in their offsprings and recognition of the need for transference of health-related advice. Simultaneously, a questionnaire was presented to their offspring to determine their perceived risk of developing diabetes and motivation toward adoption of healthy lifestyles. Results: There were a total of 100 parents (Group 1) and 100 offspring (Group 2). Only 25% of parents perceived that their children were at an increased risk of acquiring diabetes. Only 10% and 15% advised their children to adhere to diet and exercise, respectively. The mean age of the offspring was 32.30 ± 9.33 years, and the body mass index was 25.08 ± 4.58 kg/m2; 10% were detected to have prediabetes and 8% overt diabetes during the study. A higher percentage (36%) of offspring perceived an increased risk of incurring diabetes than an average person due to a positive family history, while the majority (64%) did not perceive any increased risk. Only 20% were adopting healthy eating and exercise habits. Conclusion: The awareness of the risk of diabetes among the parents and offspring was low. Even those who understand the risk did not adopt healthy lifestyles. Almost one in five offsprings who were detected to be glucose intolerant were unaware of it.

Health Promotion Interventions for Reducing Non-Communicable Diseases (NCDs) in Developing Countries: a case study of India

NCDs are responsible for a significant proportion of premature deaths in developing countries. NCDs can have significant economic costs for individuals, families, and communities in developing countries. These costs can include healthcare expenses, lost productivity, and reduced quality of life. In many developing countries, people do not have access to the healthcare services they need to prevent and manage NCDs. There are several studies conducted on health promotion interventions for reducing non-communicable diseases (NCDs) in developing countries. Some key findings from the studies included community-based interventions which have been found to be effective in reducing NCDs in developing countries. These interventions typically involve engaging community members in health education and awareness programs, providing access to healthy foods and exercise facilities, and promoting healthy lifestyles. It was concluded that effective health promotion interventions include education, improving access to healthcare and healthy food, promoting physical activity, improving water and sanitation, reducing tobacco and alcohol use, and working with communities to develop culturally appropriate strategies. Implementing these interventions requires collaboration between governments, non-governmental organizations, and community groups. Addressing NCDs in developing countries requires a comprehensive and multi-sectoral approach. By implementing effective health promotion interventions, it is possible to prevent and manage NCDs. The study recommended that governments should invest in improving water and sanitation facilities to reduce the risk of NCDs. This can include building new water and sanitation facilities, improving hygiene practices, and promoting the use of clean water and sanitation facilities. Policies should be put in place to lower the usage of fossil fuels, promote the use of clean energy, and regulate industrial and transportation emissions to improve air quality. Keywords: Non-Communicable Diseases, Health Promotion Interventions, Developing Countries, India

592-P: Exercise Training and a Chow Diet Improve High-Fat Diet (HFD)–Induced Metabolic Disorders via Different Pathways in Female Mice

Understanding the mechanism by which healthy diet or exercise training improves metabolic outcomes is crucial to developing therapeutic targets for obesity-associated diseases. In this study, female mice were fed a high-fat diet (HFD) for 12 weeks and divided into 4 groups of lifestyle interventions that followed for 6 weeks: a. HFD; b. diet-change to chow; c. HFD+exercise; d. diet-change+exercise. Age-matched mice continuously fed a chow diet served as controls. An oral glucose tolerance test was performed 48 hours after the final exercise session. HFD induced obesity, dyslipidemia, fatty liver, and impaired glucose tolerance, which were completely reversed by diet-change. Exercise alone did not change obesity but partially improved glucose tolerance and fatty liver. The increased daily energy intake caused by HFD feeding was corrected by diet-change while exercise alone increased the energy expenditure and decreased RQ. Western blotting showed that HFD decreased pAKT, pAMPKβ, Glut4, and proteins involved in β-oxidation pathways in skeletal muscles compared to controls, which was reversed by diet-change alone. Exercise training alone partially reversed pAKT and Glut4 but significantly increased proteins in β-oxidation pathways compared to controls and the diet-change group. Exercise and diet-change in combination improved metabolic outcomes similarly to diet-change alone. RNAseq of visceral adipose tissue showed that HFD modified multiple canonical pathways. Among those pathways, 1) Ca+, G-protein coupled receptor, and hepatic fibrosis signaling were reversed by diet-change and exercise training alone; 2) cAMP-mediated and ILK signaling were reversed by diet-change alone; and 3) PKA signaling was reversed by exercise training alone. Further analysis of those pathways showed several genes that were modified by HFD and reversed by all three lifestyle interventions, which could be potentially targeted for improving metabolic diseases. Disclosure L.Zhu: None. J.An: None. B.Litts: None. C.L.Atzrodt: None. J.M.Stafford: None. Funding National Institutes of Health (DK109102, HL144846, AG077038); U.S. Department of Veterans Affairs (BX005459-01)

Pengaruh Senam Jantung Sehat terhadap Perubahan Tekanan Darah pada Penderita Hipertensi di Puskesmas Passo


 
 
 
 
 
 
 
 
 
 
 
 
 The formulation of the problem in this study is whether there is an effect of healthy heart gymnastics on changes in blood pressure in hypertensive patients in the working area of the Paso Health Center. Ambon, the purpose of the study was to determine the effect of heart-healthy healthy heart gymnastics on changes in blood pressure in hypertensive patients at the Passo Health Center. Ambon. The benefit of research is that it is an input for Puskesmas to be able to increase the knowledge of puskesmas officers and for people with hypertension to prevent stroke. The research method used in this study is Quasi-Experimental research, pseudo-Pre-Experiment, namely One Group Pretest Postest with control group. The population is hypertensive patients who seek treatment at the Paso Health Center. The sample was a hypertensive patient who went to the Paso Health Center. Data analysis techniques using paired t test. Hypothesis. Is there an effect of heart-healthy exercises, a healthy heart on changes in blood pressure in people with hypertension? The results of this study found that there was a significant difference in systole blood pressure before and after heart-healthy healthy heart exercise, the statistical test results of the significancy number were 0.000 with a mean difference of 15.33, and the confidence interval value (ik 95%) was between 9.554-21.113). And there was no significant difference in diastole blood pressure before and after heart-healthy exercises, the significancy figure was 0.187 with a mean difference of 2.667 and the confidence interval value (ik 95%) was between -1.369-6.702). Based on the paired sample t test, a value of p >0.05 was obtained
 
 
 
 
 
 
 
 
 
 
 
 

Perspectives about healthy eating and exercise among patients and providers at the safety-net Lyndon B. Johnson (LBJ) hospital oncology clinic.

e24055 Background: Previous studies have described barriers and facilitators of healthy eating and exercise among cancer patients, but none have done so in a primarily low-income minority population. Understanding the perspectives of patients and providers from safety net hospitals has important implications for optimizing diet and exercise counseling and referral strategies to bridge disparities in cancer care and outcomes. Methods: The population at LBJ hospital is majority Hispanic and Black that are uninsured or underinsured. We conducted semi-structured interviews with patients who were either undergoing or completed cancer treatment at LBJ, as well as with clinic providers, to compare perceived barriers and facilitators of healthy eating and exercise. Interviews were audio-recorded, transcribed, and analyzed via hybrid analysis. Results: Thirty-one patients were interviewed, including 20 (65%) survivors and 11 (35%) who were on active treatment. Twenty-one (68%) were female, 22 (71%) Black, 5 (16%) Hispanic, and 4 (13%) other. Twenty-one healthcare providers were interviewed, including 5 (24%) physicians, 5 (24%) nursing professionals, 4 (19%) dietitians, and 7 (33%) ancillary staff. Barriers to healthy diet and exercise for patients as perceived by providers included lack of knowledge (100%), low access (80%) due to financial difficulties, transportation issues, work and family responsibilities, and low motivation (76%). This resulted in reluctance to counsel patients about healthy living, in part due to anticipated low adherence to recommendations (33%). Most patients could name components of and thought they had a healthy diet (65%), but did not exercise enough (75%) due to cancer-related physical and mental health symptoms (68%). Patients recognized benefits of healthy eating and exercise during and after cancer treatment (32% each) and recalled recommendations from providers about healthy living (48%). Patients voiced high motivation to participate in healthy eating and exercise programming (84%) and follow their medical team’s recommendations (84%), so long as programming was convenient (29%) and included flexibility of multiple options (56%). Patients acknowledged resource-related barriers to healthy living but cited proximity to grocery stores and exercise facilities (84%), help from family in cooking meals (52%), and ability to walk outside or exercise with friends (13%). Conclusions: Despite multiple barriers of capacity, opportunity, and motivation to healthy eating and exercise, cancer patients in a safety-net hospital recognized the importance of healthy living, wanted to participate in such programs, and to get additional information or referrals from their medical team. Based on these results, ongoing studies are evaluating the implementation of referral pathways to healthy living programs for cancer patients at LBJ.

P55: Phentermine-Topiramate for Weight Loss in Obese Patients with Left Ventricular Assist Devices

Study: Obesity in VAD patients has been associated with an increase in infection rates, device malfunction, cardiac arrhythmias and hospitalizaitons. Obesity can also restrict access to heart transplantation. Unfortunately, significant weight loss is difficult to achieve through lifestyle modification, especially in patients with advanced heart failure. Pharmacologic therapy for weight loss can be very effective but has not been studied in patients with LVADs. Exploring this option may limit the necessity of bariatric surgery for this patient group. Methods: We reviewed data from patients on LVAD support with baseline BMI > 40 kg/m2 who were treated with generic phentermine and topiramate for at least 90 days. Statistical analysis was performed using paired Student’s t-tests. Results: From February 2022 to September 2022, 9 LVAD patients with baseline BMI > 40 kg/m2 were prescribed phentermine and topiramate for at least 90 days. The mean weight loss was 4.02±2.7 kg (p=0.002) at 30 days. The mean weight loss was 4.17±4.9 kg (p=0.04) at 90 days. At 30 days, 8 patients lost weight (mean loss in successful group was 4.55kg) while 1 patient did not have any weight loss (Figure 1). At 90 days, 7 patients lost weight (mean loss in successful group was 5.8kg) (Figure 1). Successful weight loss with these medications was associated with patients adhering to a healthy diet and exercise regimen. Three patients had cessation of treatment during therapy: one patient had VT requiring ICD shock; one patient had recurrence of their known paroxysmal atrial fibrillation; and one patient had arrhythmias in the setting of pump dysfunction unrelated to phentermine/topiramate. Importantly, all three patients had previous history of arrhythmias and it is unknown if these agents directly contributed to their recurrence. There were no additional adverse events documented. One patient has reached a BMI of 37, making them eligible for heart transplant evaluation at our center. Conclusions: Treatment of severely obese LVAD patients with a combination of generic medications that work by appetite suppression was generally well tolerated and effective in the majority of subjects. Further study is needed to confirm efficacy and safety and to determine if there are patient characteristics that help to determine responsiveness. Follow up is ongoing and will present additional 60- and 90-day data.

Risk factors for polycystic ovary syndrome among women of reproductive age in Egypt: A case control study.

Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder among women of reproductive age, associated with an increased risk of multiple diseases, and its pathogenesis is not fully understood. Purpose: identify risk factors for Polycystic Ovary Syndrome in reproductive-aged Egyptian women attending an outpatient gynecological clinic at a specialized hospital of Obstetrics and Gynecology in Port Said City, Egypt. The study population included 248 women; 124 women suffered from PCOS and 124 Non-PCOS. Methods: - Case-control study was conducted among women. PCOS women were diagnosed clinically by transvaginal ultrasound and laboratory investigations. Data were collected using; I) a structured interview questionnaire, including socio-demographic status, medical and family history, menstrual and obstetrical history and lifestyle habits, and clinical examination; II) anthropometric parameters; III) perceived stress scale. The mean age of cases was 26.18±0.45 years. The most common risk factors for PCOS were urban residence, high education, working, insufficient income, history of anemia, hypertension, cancer, and family history of PCOS and infertility, increasing body mass index, fast food, and drinking of coffee. The study concluded that the significant risk factors for polycystic ovarian disease in Egypt women included socio-demographic characteristics, medical and family history, increasing body mass index, and lifestyle habits. This study recommended that Polycystic Ovary Syndrome women follow a healthy diet and exercise regularly.

Engaging Men of Diverse Racial and Ethnic Groups With Advanced Prostate Cancer in the Design of an mHealth Diet and Exercise Intervention: Focus Group Study.

Healthy diet and exercise can improve quality of life and prognosis among men with prostate cancer. Understanding the perceived barriers to lifestyle change and patient preferences in a diverse cohort of men with prostate cancer is necessary to inform mobile health (mHealth) lifestyle interventions and increase health equity. We conducted a multisite study to understand the preferences, attitudes, and health behaviors related to diet and lifestyle in this patient population. This report focuses on the qualitative findings from 4 web-based focus groups comprising a racially and ethnically diverse group of patients with advanced prostate cancer who are on androgen deprivation therapy. We used grounded theory analyses including open, axial, and selective coding to generate codes. Qualitative data were analyzed as a whole rather than by focus group to optimize data saturation and the transferability of results. We present codes and themes that emerged for lifestyle intervention design and provide recommendations and considerations for future mHealth intervention studies. Overall, 14 men participated in 4 racially and ethnically concordant focus groups (African American or Black: 3/14, 21%; Asian American: 3/14, 21%; Hispanic or Latino: 3/14, 21%; and White: 5/14, 36%). Analyses converged on 7 interwoven categories: context (home environment, access, competing priorities, and lifestyle programs), motivation (accountability, discordance, feeling supported, fear, and temptation), preparedness (health literacy, technological literacy, technological preferences, trust, readiness to change, identity, adaptability, and clinical characteristics), data-driven design (education, psychosocial factors, and quality of life), program mechanics (communication, materials, customization, and being holistic), habits (eg, dietary habits), and intervention impressions. These results suggest actionable pathways to increase program intuitiveness. Recommendations for future mHealth intervention design and implementation include but are not limited to assessment at the individual, household, and neighborhood levels to support a tailored intervention; prioritization of information to disseminate based on individuals' major concerns and the delivery of information based on health and technological literacy and communication preferences; prescribing a personalized intervention based on individuals' baseline responses, home and neighborhood environment, and support network; and incorporating strategies to foster engagement (eg, responsive and relevant feedback systems) to aid participant decision-making and behavior change. Assessing a patient's social context, motivation, and preparedness is necessary when tailoring a program to each patient's needs in all racial and ethnic groups. Addressing the patients' contexts and motivation and preparedness related to diet and exercise including the household, access (to food and exercise), competing priorities, health and technological literacy, readiness to change, and clinical characteristics will help to customize the intervention to the participant. These data support a tailored approach leveraging the identified components and their interrelationships to ensure that mHealth lifestyle interventions will engage and be effective in racially and ethnically diverse patients with cancer. ClinicalTrials.gov NCT05324098; https://clinicaltrials.gov/ct2/show/NCT05324098.

The Effect of Overnutrition on Mediated Collagen in Drosophila Melanogaster Physiology

Obesity affects approximately 13% of the adult population, resulting in excessive fat cell deposition and metabolic dysfunction. Collagen, a protein that supports skin regeneration, muscle building, and pain relief, is studied in Drosophila melanogaster under different diet conditions. This experiment aims to test whether overnutrition affects physiology and collagen due to any anatomical changes in Drosophila Melanogaster, more commonly known as fruit flies. The research conducted over several weeks utilizes two diets: an obesity-inducing diet containing excessive glucose and coconut oil and a traditional diet of blue food medium, yeast, and water. The study groups include a wild-type, collagen-mutated, and obesity-mutated group, with multiple assays measuring how the obesity-inducing diet affects each population and their collagen levels. The results reveal that the obese group experienced higher food consumption levels but had lower locomotive ability than the other test groups. Hydroxyproline, the building amino acid for collagen, and collagen levels were higher in the obesity mutant than in the wild-type and collagen mutated group. The study shows that anatomical changes in organisms are influenced by both diet and movement. The obesity group, on an obesity-inducing diet, experienced decreased movement related to increased food intake and decreased neural activity. The high-fat and high-sugar diet suppressed neuronal autophagy, created inaccurate hunger and satiety perceptions, and increased collagen deposition. Anatomical changes were observed in collagen-heavy tissue areas, whereas decreased neural activity and increased feeding rates were behavioral changes. The study emphasized the importance of a healthy diet and exercise in promoting overall health.

The effects of voluntary exercise on histological and stereological changes of sciatic nerve, nitric oxide levels, and peripheral neuropathy caused by high-fat diet-induced type 2 diabetes in male rats

This research was conducted to investigate the possible beneficial impacts of voluntary exercise on sciatic tissue, nitric oxide levels, stereological changes, and peripheral neuropathy caused by "high-fat-diet (HFD)"-induced "type 2 diabetes mellitus (T2DM)" in male rats. Rats were put into four experimental groups at random: "healthy control (C), voluntary exercise (VE), diabetic (D), and diabetic rats treated by voluntary exercise (VED)"; each group contain eight animals. Animals in VE and VED groups performed "voluntary exercise (VE)" for ten weeks. Animals in D and VED groups became diabetic after receiving a HFD for four weeks and an intraperitoneal injection (IP) of "streptozotocin (STZ)" (35 mg/kg). In order to evaluate mechanical and thermal algesia, hot plate, tail withdrawal, and von Frey tests were carried out. At the end of this study, serum NOx levels were assessed, and histological and stereological analyses were conducted. Mechanical nociceptive thresholds indicated considerable reduction (p < 0.001) which was followed by a remarkable enhance (p < 0.001) in thermal nociceptive threshold of D group. Tissue changes were also seen in sciatic nerve of D group. Voluntary exercise modified thermal and mechanical sensitivity in diabetic rats. It also improved the damaged sciatic nerve in diabetic animals.

Detecting informal green, blue, and street physical activity spaces in the city using geotagged sports-related Twitter tweets.

Finland's natural physical environment and climate support a wide variety of informal outdoor sports, thereby motivating the population to do physical exercise in scenic environments. The vast majority of Finns enjoys outdoor recreational activities, and could thus be encouraged to post accounts of their year-round activities on social media. Our aim was to find out in what kind of areas and spaces, spatially, users are tweeting about sporting activities. We use geotagged Twitter tweets filtering for 16 sporting activity keywords in both English and Finnish. The case study was conducted in the Helsinki Metropolitan Area, Finland, with an emphasis on cross-country skiing as a sports activity when there is snow. In a secondary analysis we concentrated on the sports people were practicing in these locations when there was no snow. The location spaces are split in to three land cover types: green, blue, and street spaces. We found that approximately half of the 150 skiing-related tweets were geotagged in green spaces, and half in street spaces. This finding related to street space was attributable to a spatial scale error: when we checked the results manually we noticed that they referenced the sporting location in the green space. Hence, then over 90% of the 745 non-ski-related tweets were geotagged in a street space. We conclude that Twitter is a beneficial tool for detecting spaces used for informal physical activity. A shortcoming in current Finnish national sporting policies is that spaces for informal physical activity are not explicitly mentioned- we use the term informal with reference both to the space and to the sporting activity, whereby public spaces are used for physical activity. This new knowledge of sporting locations will help city planners and sports planners to improve informal sports facilities, which in turn will promote healthy exercise in cities.

The interplay of ADHD symptoms and exercise in youth

The interplay of ADHD symptoms and exercise in youth

Lifelong voluntary aerobic exercise-mediated preservation of physical function is related to changes in the plasma metabolome in aged mice

Declines in physical function with aging (i.e., grip strength, endurance, and coordination) are strongly linked to age-related diseases, and the plasma metabolome can predict the progression of healthy aging. A single bout of aerobic exercise induces changes in plasma metabolites that are implicated in healthy aging and lifespan (e.g., tRNA biosynthesis is required for protein synthesis; arginine biosynthesis contributes to nitric oxide production and skeletal muscle function; TCA cycle metabolites aid in cellular energy production). Moreover, lifelong voluntary aerobic exercise (VAE) preserves physical function with aging, but its relation to the plasma metabolome is unknown. Hypothesis: Lifelong VAE-mediated preservation of physical function is related to changes in the plasma metabolome. Design: We performed a secondary analysis of data from a lifelong study in male C57BL/6 mice, in which mice that engaged in voluntary wheel running (model of VAE; initiated at 3 mo) were compared to sedentary age-matched controls (SED) (n=8-9/group). Grip strength, endurance, and coordination were assessed at 6 and 18 mo. The plasma metabolome was measured at 19 mo by mass spectrometry. Group differences in metabolites were identified using independent t-tests (p&lt;0.05) following a Shapiro-Wilk test of normality. Then, KEGG pathway analyses (Metaboanalyst) were used to identify metabolic pathways changed with VAE (p&lt;0.05; false discovery rate&lt;0.20). Finally, simple linear regressions were used to assess the relation between the magnitude of change in grip strength, endurance, and coordination from 6 to 18 mo and plasma metabolite concentrations (all p&lt;0.05). Results: At 19 mo, VAE mice ran 3.2±0.1 km/day (mean±SE). Physical function was preserved from 6 to 18 mo (% decline) with VAE vs SED: grip strength, 0.4±1.7% vs 12±4.0% (p&lt;0.05); endurance, 1±15% vs 61±5% (p&lt;0.05); coordination, 10±4% vs 73±10% (p&lt;0.05). Group-related differences in plasma metabolites were identified at 19 mo: 23 single metabolites (p&lt;0.05) and 7 metabolic pathways. The top altered metabolic pathways are implicated in healthy aging (e.g., tRNA and arginine biosynthesis) and exercise metabolism (e.g., TCA cycle). Metabolomic differences in the VAE mice were associated with preservation of physical function: spermidine and DHA omega-3 fatty acid correlated with the change in grip strength, spermidine and L-ornithine correlated with the change in endurance, and 9 metabolites (e.g., citrate and spermidine) correlated with the change in coordination. Conclusions: We show associations between the preservation of physical function with lifelong VAE and plasma metabolite abundance. Plasma metabolomic differences in aged mice following lifelong VAE are consistent with observations of corresponding changes in response to acute exercise in young endurance trained adults. Changes in the plasma metabolome reflect preserved physical function with lifelong VAE. NIH T32 DK007135, R01 HL107120, K99 HL159241 This is the full abstract presented at the American Physiology Summit 2023 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Bimbingan Motorik Anak Meleui Senam Sehat Di TK Al- Karimah Pekanbaru

Al-Karimah Kindergarten (TK) Is one of the kindergarten schools in the handsome sub-district of Pekanbaru City. The number of children participating in healthy exercise is 25 people, this is due to maintaining their health after the pandemic. the implementation of children's motor guidance service activities through healthy gymnastics at Al-Karimah Kindergarten Pekanbaru aims to improve children's motor skills through healthy gymnastics. This service is carried out through the Hero University research and community service center in collaboration with the principal of the Al-Karimah Kindergarten. The results obtained by this activity are through healthy gymnastic movements that can improve the motor skills of children in Al-Karimah Kindergarten. And can help teachers in solving problems that exist in kindergarten.

The Correlation between Age, Fat Intake, and Visceral Fat and Body Mass Index at the Gym

Background: This study aimed to investigate the correlation between age, fat intake, visceral fat, and body mass index (BMI) of gym members. Methods: A cross-sectional approach was employed with a sample of 87 respondents. Primary data were obtained from three different gyms, while secondary data was obtained from gym owners. A questionnaire was used as the research instrument, and the Chi Square test was used for data analysis. Results: The majority of respondents had a higher fat intake than recommended, and most had high levels of visceral fat. In terms of BMI, the majority were classified as either overweight or obese. Bivariate analysis showed significant correlations between age, fat intake, and visceral fat with BMI among gym members. Conclusion: This study found that age, fat intake, and visceral fat were significantly correlated with BMI among gym members. The findings suggest the importance of promoting healthy dietary habits and exercise among gym members, particularly those older or with high visceral fat levels.