Health Risks Of Metals Research Articles

Seasonal variations, source apportionment, and health risk assessment of trace metals in PM2.5 in the typical industrial city of changzhi, China

Studying the source-specific health risks of trace metals in PM2.5 is important for controlling its emission sources that are hazardous to human health. In this study, PM2.5-bound trace metals were analyzed during winter, spring, summer, and autumn in 2018 in Changzhi, a typical industrial city in China. The results revealed that the annual concentration of total trace metals in PM2.5 was 7531.9 ng m−3 in the study area, and the concentration was maximum in spring (14,781.7 ng m−3), followed by autumn (7163.8 ng m−3), winter (5237.0 ng m−3), and summer (3226.1 ng m−3). Dry and continual windy days in spring often led to high concentrations of trace metals in Changzhi. Trace metals with high enrichment factor (>100), such as Cd, Sn, Pb, and Zn, were predominantly released from coal combustion. Four sources, such as coal combustion, traffic emissions, resuspended dust, and industry, were established by positive matrix factorization, with contributions to PM2.5-bound trace metals of 29.5%, 26.6%, 26.3%, and 17.6%, respectively. In terms of their contribution to cancer risk, the top contributor both for children and adults was industry, with 1.50×10−6 and 5.99×10−6, respectively, both of which were higher than the safe level (1 × 10−6); coal combustion ranked second (0.49 × 10−6 and 1.94 × 10−6 for children and adults, respectively). In addition to the advancement of control measures for pollutants and control of industrial production, more attention should also be given in limiting coal consumption through the use of clean energy (e.g., natural gas).

Selected Mollusks from Pujada Bay, Philippines: Heavy Metal Health Risk Assessment and Antibacterial Activities

Selected Mollusks from Pujada Bay, Philippines: Heavy Metal Health Risk Assessment and Antibacterial Activities

A comparative study on the metal loads and related human health risks of toxic metals between the vegetables from Southern and Northern regions of Nigeria consumed in Akwa Ibom State

Vegetables are consumed in both the developing and developed countries of the world due to their high nutritive values, however they also contain some high levels of toxic substances including metals. This research examined the variations in toxic metal loads between the vegetables from the southern and northern parts of Nigeria consumed in Akwa Ibom State. This study also assessed the sources of these toxic metals in the studied vegetables from both regions of the country. The cancer and non-cancer health risks related to the consumption of these vegetables by the adults and children populations were investigated. The results showed higher levels of As, Cd, and Ni in vegetables from the North than in the South; the levels of Cr were higher in vegetables from the South, whereas the levels of Pb varied between the vegetables from both regions. The difference in the variations in toxic metal levels was significant at p < 0.05 for As and Ni. The study identified two major separate factors responsible for the accumulation of toxic metals in the studied vegetables from both regions. The results also revealed that the consumers of these vegetables were not exposed to serious cancer and non-cancer health risks however, were exposed to more Cd via the consumption of Solanum lycopersicum. It was also observed that the consumers were more expose to the carcinogens through the consumption of vegetables from the north and the children were more susceptible.

A comparative study on the metal loads and related human health risks of toxic metals between the vegetables from Southern and Northern regions of Nigeria consumed in Akwa Ibom State

A comparative study on the metal loads and related human health risks of toxic metals between the vegetables from Southern and Northern regions of Nigeria consumed in Akwa Ibom State

Bibliometric overview of research trends on heavy metal health risks and impacts in 1989–2018

Health risks caused by heavy metal pollution are one of the most concerning issues globally due to heavy metal toxicity, carcinogenicity, bioaccumulation, and complex mechanisms with multiple sources and pathways. Much effort has been devoted to researching heavy metal emissions, pollution, health risk assessments, and mitigation strategies in past decades. In this study, a bibliometric analysis of heavy metal health risks and impacts was performed to obtain an overview of the health risk levels, sources and control strategies of heavy metals in various regions worldwide in 1989–2018. The results showed there was a significant increase in the concern over heavy metal risks and impacts in the past ten years, especially in China and other developing countries. China surpassed the USA and became the most productive country in 2010; furthermore, China has contributed to nearly one-half of the total growth caused by increasing concerns about severe heavy metal pollution issues. The most concerning issues can be categorized into five hotspots: 1) soil-to-plant-to-dietary intake is the primary exposure pathway for public health, with the main pollutants being Cd, As and Pb, especially in China and other developing countries; 2) fish/shellfish consumption is the main exposure pathway for Hg intake, which is especially affected by methylmercury bioaccumulation in aquatic organisms; 3) the reduction of health risks caused by arsenic in drinking water, especially in Bangladesh and Pakistan due to natural geochemical sources, is important; 4) heavy metals in road dust and room dust combined with atmospheric emissions and air quality represent a research hotspot in the last decade; and 5) comprehensive assessment methods and related policies are popular research topics.

Determination of essential and toxic elements content of Turkish peanut and assessment of health risk

ABSTRACT Peanut (Arachis hypogaea L.), which is one of the most important members of the legumes family, contains appreciable amounts of high-quality dietary oil and vegetable protein. It can be added to many foods to enhance their levels of high-quality protein in diets lacking in nutrition. In this study, 18 essential elements (V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Se, Mo, Mg, P, S, K, Ca, Cl, Br and I) and 4 non-essential potentially toxic elements (Cd, Sn, Hg, and Pb) in 42 peanut samples from Mediterranean region of Turkey were analysed by using an energy-dispersive X-ray fluorescence spectrometer. The most abundant essential elements of K, P, S, Ca, Mg and Cl were determined with average concentrations of 13437, 5058, 3451, 1786, 1759 and 209 mg kg−1, respectively. The daily intake of potentially toxic elements for an adult person due to the consumption of peanuts was estimated based on the measured concentrations of the potentially toxic elements (V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sn, Cd, Pb, and Hg). The results revealed that peanut samples contain health-enhancing nutritional elements and consumption of peanut samples as food does not pose any health risk for toxic metals.

Health risks of metal(loid)s in maize (Zea mays L.) in an artisanal zinc smelting zone and source fingerprinting by lead isotope

Metal(loid) contamination caused by industrial activities in agricultural soils has become a universal environmental and food safety concern. This study revealed the contamination, pathway, and source contribution of metal(loid)s such as lead (Pb), zinc (Zn) and cadmium (Cd) in maize and soils in different residential areas impacted by long-term historical artisanal zinc smelting activities from Southwest China. Results revealed that the soils were contaminated heavily by metals like Pb, Zn and Cd, with contents of 40–14,280, 150–47,020 and 1.28–61.7 mg/kg, respectively. Hazard quotients of food uptake for Pb, Cd and Cr in maize grains were extremely high for residents, in particular for the children. To trace the sources of metal health risk, lead isotope fingerprinting and binary mixing modeling were applied. It indicated that the anthropogenic activities contributed over 80% to the Pb contamination in maize grains. The findings highlighted warning levels of health risks to the residents in consuming maize grains in the historical artisanal PbZn smelting area. Therefore, an effective strategy including pollution source control and remediation measures must be taken to improve the soil quality and guarantee food safety around the historical smelting areas likewise.

Fingerprint characteristics and health risks of trace metals in market fish species from a large aquaculture producer in a typical arid province in Northwestern China.

Concentrations of nine metals were measured in eight common cultured fish species obtained from forty-three aquatic product markets across three cities in Xinjiang province, to establish fingerprint characteristics and assess potential human health risks due to the consumption of fish. Metal levels (g/kg, wet weight) in fish muscles were: 1204.88–5113.19 Al, 2.09–12.44 V, 6.10–31.86 Cr, 2368.80–8949.52 Fe, 2.01–10.26 Co, 4082.72–12785.68 Zn, 174.89–763.83 Cu, 0.33–2.24 Cd, and 5.74–9.90 Pb. Fingerprint analysis revealed that the studied fish species from the three cities exhibited a similar pattern of distribution. From the viewpoint of human health, the assessment of non-carcinogenic risk indicated no significant adverse health effects due to consumption of the assessed fish species.

Bioaccessibility and health risk assessment of trace metals in soils of greenhouse vegetable production near the industrial areas of the Yangtze River Delta, China.

As a common environmental problem in China, trace metal accumulation and contamination in soils of greenhouse vegetable production (GVP) may pose significant health risk via oral ingestion, inhalation, and dermal contact to vegetable farmers and children playing in greenhouse fields. Thus, bioaccessibility and health risk of Cr, Ni, Cu, Zn, Cd, and Pb in GVP soils collected from 13 GVP farms or bases near industrial areas of the Yangtze River Delta, China, were investigated as a case study. The results suggested that both GVP and industrial discharges contributed a lot to accumulation or contamination especially of Zn and Cd in soil, which subsequently increased their bioaccessible concentrations. In addition, soil acidification caused by GVP also increased bioaccessible Cr and Ni concentrations in soil of the Anthrosols study area. However, the health risk assessment of metals in GVP soil through inhalation and oral ingestion considering metal bioaccessibility suggested no non-carcinogenic and carcinogenic risks to both farmers and children. In contrast, there was potential carcinogenic risk within acceptable level posed by Cr in GVP soil through dermal contact to farmers and children. This indicates that both GVP and industrial activities had limited effect on health risk of trace metals in GVP soil via ingestion, inhalation, and dermal contact. However, the carcinogenic risk posed by Cr, which mainly originated from natural sources, still cannot be negligible. Overall, the results will provide valuable information for decision-makers to develop reasonable strategies and guidelines for risk management of trace metals in GVP soil.

Heavy metal intake and health risk implications from consumption of dried pulses in Trinidad and Tobago, W.I

ABSTRACT The increase in urbanisation and industrialisation have contributed significantly to elevated concentrations of heavy metals in soils. The eventual uptake of heavy metals by agronomic crops could potentially affect human health based on consumption patterns in various regions of the globe. This study investigated the potential health risks to consumers of dried legumes in a small island developing state that rely primarily on the importation of those crops from major producers. Several varieties were analysed for selected heavy metals in which Cd and Pb were not detected and Cr was only present in certain legumes. The concentrations of Cu, Mn, Ni, and Zn were all below the established World Health Organisation (WHO) maximum permissible limit (MPL) and the target hazard quotient (THQ) and hazard index (HI) values were below one for all samples, suggesting no non-carcinogenic risk to consumers.

Environmental, ecological and health risks of trace metals in sediments of a large reservoir on the Euphrates River (Turkey)

The contents of trace metals (Cd, As, Pb, Cr, Cu, Zn, Ni, Co, Mn and Fe) in sediment samples from eleven sampling sites in The Keban Dam Reservoir, which is Turkey's second biggest reservoir, were examined to evaluate spatial distribution, possible sources, contamination status and environmental, ecological and health risks of these metals. The results indicated that enrichment factor, geoaccumulation index and contamination factor values were higher at sampling sites receiving industrial and domestic wastewater discharges. Only Cr and Ni concentrations exceeded their corresponding probable effect concentrations in 47.7% and 93.2% of the samples. Ecological risk factor and ecological risk index values at all sites were <40 and <150, respectively, indicating low ecological risk in the reservoir. Cluster, correlation and factor analyses suggested that Cr and Ni originated from mixed sources of lithogenic and anthropogenic origins, while other metals mainly originated from natural sources. For children and adults, hazard quotient value of each metal from ingestion and dermal contact pathways did not exceed 1. Carcinogenic risk (CR) values of arsenic from these two exposure pathways and total CR value were within the range of acceptable risks. Thus, in terms of recreational uses, the reservoir is considered to be safe for human health.

Ecological and Human Health Risks of Heavy Metals in Shooting Range Soils: A Meta Assessment from China.

Contamination of shooting ranges by heavy metals in particular Pb represents a widespread environmental issue attracting concern worldwide. Contaminant accumulation in shooting range soils can pose potential ecological risks and health risks for shooters and workers. Based on the published data on metal contamination at five shooting ranges in China, potential ecological and human health risks of several metals, and in particular, Pb were assessed for the five surveyed shooting ranges. Data show the mean concentrations of Pb, Cu, Hg, Sb, Ni and Cr in various ranges were all higher than the local soil background values, implying their accumulation was induced by shooting activities. The degree of contamination varied with sites and metals, very high Pb contamination at Range 1, Range 2 and Range 5-1, while moderate Pb contamination at Range 3 and Range 5-2. Comparatively, As, Zn and Co showed no contamination. Among the surveyed metals, Pb, Cu, Hg and Sb in shooting range soils displayed relatively high potential ecological risks. The overall degree of potential ecological risk was very high at Range 1 and Range 2, considerable at Range 4 and Range 5-1, and low at Range 3 and Range 5-2. The mean HI (hazard index) of Pb at Range 2 and the maximum HI values at Range 1 and Range 4 were higher than 1, suggesting a possibility of non-carcinogenic risks of Pb contamination at these sites. However, Pb in other range soils and other metals, across the five ranges, all exhibited no non-carcinogenic risks. The cancer risks of the four carcinogenic contaminants (As, Co, Cr, and Ni) were acceptable or negligible at all ranges. In conclusion, contamination of Pb and other metals such as Cu, Hg and Sb can cause various potential ecological risks at all the surveyed ranges, but only Pb at three ranges shows possible health risks. Contamination of Pb in the surveyed shooting ranges should be managed to reduce its possible environmental and health risks.

Potential ecological and health risks of toxic metals associated with artisanal mining contamination in Ijero, southwest Nigeria

This investigation was done to decide the concentrations, sources and potential risks of metals in media around Ijero area. A total of 80 samples including topsoils, sediments, tailings and whole plants were gathered from this territory while control samples were taken from zone with less human exercises. Samples were pounded, sieved and chemically analyzed utilizing Agilent High Plasma Liquid Chromatography Inductively Coupled Plasma-Mass Spectrometer. Results demonstrated that the mean concentrations of lead (Pb) and zinc (Zn) in soils are 30.61 and 123.71 µg/g individually. In tailings the mean distribution of Pb and Zn are 33.16 and 22.44 µg/g each. Toxic units in all media were less than 4, indicating low effect on the ecosystem. Bivariate correlation, hierarchical cluster and principal component analyses revealed that metals in media from this area originated from mining and mineral processing activities, mixed and geogenic sources. Study revealed that metals in the media pose high degree of contamination and moderate to high ecological hazard. Also, there is high cancer-causing hazard index (HI) (10−6–10−4) and non-cancer-causing (HI > 1) dangers which is more articulated in kids than the grown-ups. It is important to introduce measures that will decrease the negative impacts associated with mining in the area.

Determination and characterization of metal nanoparticles in clams and oysters.

With the extensive application of nanotechnology, metal nanoparticles (MNPs) have been widely used, thus are universally detected in the environment. This has caused increasingly concerns due to their toxicity and the potential health risks they pose to humans. In this work, the concentrations and particle size distributions of MNPs and concentrations of associated metal ionic species in shellfish seafood (clams and oysters) were investigated using single particle inductively coupled plasma mass spectrometry (sp-ICP-MS) and inductively coupled plasma mass spectrometry (ICP-MS). The MNPs in the clam and oyster tissues were extracted via an alkaline digestion method with a recovery rate of 95.9% (for gold nanoparticles (AuNPs)). Then total concentrations of 41 metal elements were measured in the two types of seafood, of which 20 were selected for sp-ICP-MS analysis. The results showed that 5 types of MNPs were detectable in clams (Y, La, Ce, Pr, Gd) and 5 types of MNPs were detectable in oysters (Y, La, Ce, Pr, Nd). Size distributions of MNPs in clams and oysters were in the range of 35-55nm and 30-65nm, respectively. Nanoparticle concentrations in clams and oysters ranged from 0.6 to 37.7ng/g and 4.2-19.7ng/g, and accounted for 3.4%-50% and 5.5%-46% of the total metal content, respectively. Based on this analysis, the health risks of metals in the two kinds of seafood were evaluated by comparing the Provisional Tolerable Weekly Intake (PTWI) with limits recommended by the World Health Organization (WHO)/Food and Agriculture Organization (FAO). These results provide important information about the presence of metal nanoparticles in seafood and, to the best of our knowledge, this is the first time that the nanoparticles of rare earth elements have been detected and reported in bivalve mollusc tissues.

Human health risk assessment of heavy metals from surface water of Chott Merouane, Algeria

ABSTRACTToday, human health risk caused from exposure to heavy metals in water is a great international concern. Therefore, this study was performed to investigate the content of Cadmium (Cd), Chromium (Cr), Copper (Cu), Iron (Fe), Manganese (Mn), Nickel (Ni), Lead (Pb) and Zinc (Zn) in surface water (24 samples) of Chott Merouane and to estimate the potential health risks of metals to humans. The concentrations (mg/L) of metals ranged between 0.05 and 0.89 for Cd, bDL (below detection limit) – 2.05 for Cr, 0.03–0.27 for Cu, 0.4–7.4 for Fe, 0.15–1.19 for Mn, 0.27–4.53 for Ni, 0.23–5.87 for Pb, 0.01–0.28 for Zn. Both non-carcinogenic and carcinogenic health risks via oral and dermal absorption pathways were evaluated from two exposure scenario (Residential and Industrial scenario). For the first scenario, the Hazard Quotient (HQ) and Hazard index (HI) for both the children and the adult via oral pathway were less than one, whereas HI for children was greater than one (1.36) indicating an unacceptable risk of non-carcinogenic effects on child health. Carcinogenic Risk (CR) was found within the USEPA’s acceptable cancer risk range of 10−6–10−4. For the industrial exposure, the HItotal at S1, S2 and S7 were slightly higher than the acceptable guideline (1.47, 1.98 and 1.11, respectively). Also, the CRtotal of Cr at these stations was slightly higher than the acceptable cancer risk range (1.8E-04, 1.6E-04 and 1.7E-04, respectively). Both non-carcinogenic and carcinogenic risks were mainly attributed to the oral pathway. The findings of this study indicating minor adverse health risk but suggest necessary conservation and management measures should be taken to improve the water quality of this Ramsar wetland.

Health risk assessment of heavy metal and its mitigation by glomalin-related soil protein in sediments along the South China coast

Knowledge regarding the exposure risk of heavy metals in estuarine wetland is important for people (especially fishermen and consumers of local fish) living in the coastal area and the coastal reclamation. Here, we assessed the ecological and human health risks of sediment-associated metals in the large-scale estuary area based on different sediment textures (Mud, Mud-Sand, and Sand). To investigate the potential impact of terrestrial material on the contamination risks, glomalin-related soil protein (GRSP), a recalcitrant soil protein fraction, was used. Results showed that the estuarine sediment texture played a rather important role in the heavy metal distribution, risk assessment, and the metal sequestration capacity of the land-derived GRSP fraction. We found arsenic, Pb, Cd, and Cr had the highest enrichment in the estuarine wetlands by calculating multiple contamination indices, and that confirmed similar findings of heavy metal contents, except Cd. The average pollution load index (PLI) was 1.67 in all the estuarine sediments, indicating multi-element contamination, with the Muddy sediments (PLI = 2.07) significantly higher than the Mud-Sand mixed sediments (PLI = 1.85), and the lowest (0.78 < 1) in the Sandy sediments. The health risk assessment suggested that the potential cancer risk occurred (>1.00E-6) but no obvious non-carcinogenic effects occurred (<1). Arsenic was found to be the primary contributor to non-carcinogenic risk, accounting for 44.2% of hazard index, while Ni is the primary control metal for carcinogenic risk (except arsenic in the Sandy sediments). As a proxy of terrestrial organic matter, GRSP fraction possessed a high sequestration capacity for heavy metal, especially in the Sandy sediments, and it was significantly associated with the mitigation of ecological and health risks, which may provide new insights into the in situ remediation of anoxic estuarine wetlands.

Health risks associated with multiple metal(loid)s in groundwater: A case study at Hetao Plain, northern China

To compare the health risks of multiple metal(loid)s in groundwater, and discuss the feasibility of drinking water standards, 66 groundwater samples were collected from the Hetao Plain in October 2017. Eighteen metal(loid) species (boron (B), manganese (Mn), iron (Fe), strontium (Sr), barium (Ba), lithium (Li), scandium (Sc), titanium (Ti), vanadium (V), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), selenium (Se), rubidium (Rb), molybdenum (Mo), uranium (U)) were analyzed, and the related non-carcinogenic risks were assessed. The results showed that 83.3% of the groundwater samples had As and Fe contents above the maximum allowed contaminant levels (MCLs) in drinking water standards, followed by Mn (70.2%), B (65.2%), Se (60.6%), U (18.2%), Ni (18.2%) and Mo (1.50%). Compared with the dermal exposure pathway, oral ingestion made a risk contribution of more than 99% for all target metal(loid)s. Site-specific hazard quotient (HQ) values ranged from 2.30E+00 to 1.75E+02, indicating that multiple metal(loid)s in the drinking groundwater cause a serious non-carcinogenic risk to the local people. The risk contributions (mean value) were ranked as As (55.2%) > U (25.5%) > Li (10.8%) > other total metal(loid)s (8.60%), and the contributions of U and Li could reach 91.7% (site 20) and 69.8% (site 56), respectively. The calculation of specific health risks further indicated that the MCLs of metal(loid)s do not match the corresponding health risk well. Some metal(loid)s such as Li that showed high exposure risks in this study, still have no MCL values until now. Therefore, current drinking water standards need to be updated.

Occurrence, sources and health risks of toxic metal(loid)s in road dust from a mega city (Nanjing) in China

Potential toxic metal(loid)s (PTMs) in road dust are a major concern in relation to urban environmental quality. Identifying pollution hotspots and sources of PTMs is an essential prerequisite for pollution control and management. Herein, the concentrations, pollution and potential health risks of 8 PTMs (As, Cd, Co, Cu, Hg, Mo, Pb and Zn) in road dust from the highly urbanized areas of Nanjing were studied. Spatial occurrences and sources of PTMs were explored using geostatistics, principal component analysis (PCA) and local Moran’s index. The contamination factor (CF) results showed that Co was mainly natural in origin, while the other PTMs were polluted, with average CFs ranging from 1.4 to 11.0 as follows: Hg > Mo > Cd > Cu > Pb > Zn > As, indicating moderate to very high contamination. Except for Co and Hg, the other PTMs were heavily loaded on PC1, which explained 44.72% of the total variance. Combining the statistical results and distributions of potential sources, we deduced that industrial emissions dominated the spatial patterns of all polluted PTMs in road dust, which showed high levels in the northern parts of the study region and generally decreasing levels southwards. Moreover, Pb and Zn in the south-central area and Cd in the north-central area displayed hotspots, with maximum CFs of 5.5 (Pb), 4.2 (Zn) and 16.2 (Cd), which were related to additional automotive and railway braking emissions, respectively. The resuspension of legacy pesticides in soil is likely responsible for the As pollution hotspot in the southwestern part. Despite the high anthropogenic contributions (27% for As and 68–88% for the other metals) to the PTMs in road dust, their noncarcinogenic and carcinogenic health risks were rarely found for children and adults based on the values of the hazard index and carcinogenic risk index. However, attention still should be paid to the pollution hotspots in the northern region.

Chemical characteristics and health risks of trace metals in PM2.5 from firework/firecracker burning during the Spring Festival in North China

Firework/firecracker (FF) burning can significantly deteriorate air quality, whereas little is known about its influences on the elemental composition and associated health risks. Fine particles (PM2.5) and trace elements were characterized based on a multi-site campaign at Chifeng, China around 2016 Chinese Spring Festival (SF). Severe pollution levels average of 57.70 μg m−3 were observed during the SF with maximum to 471.00 μg m−3 shortly after the intensive FF activities. Largely enhanced PM2.5-bound metals were found in both urban and rural sites especially for K (8.27±5.36 μg m−3) and Al (2.36±1.41 μg m−3). Ba and Sr as the tracer of fireworks also increased more than 20-fold compared to non-SF period. Accordingly, FF burning factor identified via PMF model contributed significantly to the total elemental mass (71.34±24.94%) during the SF. Its major impacts on both crustal elements as Al, Ca, K and heavy metals as Cr, Cu and Pb were both identified. Elevated non-cancer risks (0.76 to children, 0.11 to adults) and cancer risks (3.96 × 10−6) were assessed during the SF, with As, Cd, Pb exerted the most adverse threats. The FF burning contributed the second largest share of the health threats after coal combustion, accounted for 28.35% and 12.64% of non-cancer risks for children and adults, respectively, and 10.03% of cancer risks, respectively. This study provided scientific evidences for stricter firework/firecracker regulations to protect public health.

Pollution and health risk assessment of toxic metal(loid)s in soils under different land use in sulphide mineralized areas

Toxic metal(loid) pollution in sulphide mineralized area has been increasingly concerned. In the present study, the pollution characteristics and the health risk of Hg, As, Tl and other metal(loid)s in soils under different land use, from a rural area impacted by Tl-Hg-rich sulphide mineralization, were assessed using statistical analysis, enrichment factor (EF), potential ecological risk index (RI) and health risk assessment model. The results showed that Tl, Hg and As were highly enriched in the mine area due to the historic sporadic mining activities, and Tl, Hg and Sb were enriched in the peripheral area. Hg and Tl pollution in soils of the mine area impacted by past mining activities posed high ecological risk. High contents and enrichment of Tl and Hg in forest/grass land had a greater impact on the ecological risk in the mine area; whereas Tl and Hg in the grain land and vegetable land dominated the soil ecological risk in the peripheral area. Human health risk assessment indicated that children are more sensitive and vulnerable to toxic metal(loid)s in soils than the adults. Hg, Tl and As have potential non-carcinogenic risk to local children and adults. The HQ levels for different exposure pathways of toxic metal(loid)s were in the order of ingestion > dermal contact > air inhalation for Tl and As, and dermal contract > ingestion > air inhalation for Hg. For carcinogenic risk, all the mean CR values of ingestion in the mine area were higher than 10−4, indicating seriously potential risk. The descending order of ILCR via different pathways was the same as the HQ, for which ingestion was predominant, followed by dermal and air inhalation. The findings may help provide basic knowledge and guidelines for toxic metal(loid) pollution remediation in similar sulphide mineralized areas.