ISEE-29 Introduction: Since year 1997, the EMECAS project evaluates the effect of current air pollution on the health of urban population in Spain. In this paper we present the results for the association between gaseous air pollution and hospital admissions for cardiovascular diseases. Methods: Daily emergency admissions for all cardiovascular diseases (CVS) (ICD-9: 390–459), heart diseases (HD) (ICD-9: 410–414, 427, 428); ischemic heart diseases (IHD) (ICD-9: 410–414), and cerebrovascular diseases (Stroke) (ICD-9: 430–438) were collected from hospital records (1995–1999). Air pollutants data were obtained from local networks. Variables for 24 hours daily levels of SO2, and NO2; 8 hours maximum moving average of CO and ozone; and, lastly, 1 hour maximum of SO2, NO2 and ozone were constructed. Magnitude of association in each city was estimated using generalized additive models (GAM) of Poisson controlling for confusion and overdispersion. Lagged effects, up to three days, for each cause and pollutant were examined. Data were analysed using S-Plus GAM function with more stringent convergence criteria. Combined estimates were obtained under a ′fixed effects’ model, and, if heterogeneity, under ’random effects’ one. For ozone the analyses were restricted to the warm period (May to October). Results: Concurrent and one day were the most consistent lags showing associations, only ozone showed a more delayed relationship. In the combined estimates an increase of 10 ug/m3 in SO2 daily levels was associated with a 1.3% (95% CI: 0.2–2.5%) increase in the number of hospital admissions for CVS, and 1.7% (95% CI: 0.7–2.9%) for HD. The same increase in concentrations of NO2 was significantly associated with a 0.4% increase in CVS, and 0.9% in HD admissions. For ozone the corresponding estimates were 0.7 in both cases. An increase in 1 mg/m3 levels of CO was associated with an increase of 2.1% in CVS, and 4.2% in HD admissions. Only ozone presented some suggestion of association with stroke. In two pollutant models the coefficients of SO2 and NO2 were affected after control for other pollutants. On the contrary, CO and ozone were unaffected by the inclusion of the second pollutant. Conclusions: A short-term association between increases in daily levels of air pollutants and the number of daily admissions for cardiovascular diseases in the Spanish cities was found with greater estimates for heart diseases. CO and ozone showed an independent effect of the other pollutants.
Read full abstract