In this 21st century era student health literacy is becoming increasingly important to improve and can see as an asset for students. Assessment for learning are viewed as powerful levers for improving student health literacy by giving feedback, so student as learners know their strengths and weaknesses and how to improve their learning. This study aimed to investigate Edmodo as Assessment for learning to assess student performance during the biology learning process. Data collection techniques used are teachers and students questionnaires, documentation, and students digestive system tasks based on health literacy indicators. The analytical technique used in this study is descriptive method. The result showed improvement students average score from task 1 to task 2 in every indicators that indicate by using Edmodo students can improve 4 dimension of health literacy indicators based on Partnership-21 Century Skills frameworks.
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