Introduction: One of potential public health issues in Indonesia is the problem of Adolescent Reproduction Health (ARH), particulary the behavior of having sex premaritaly and promiscuity, which is at risk of having unwanted pregnancy and sexually transmitted deseases such as HIV/AIDS. Increase in student’s knowledge, attitude, and skill by application of education of adolescent reproduction health (EARH)is hopefully will reduce the ARH problem.Method: This was experimental research with randomized pretest-posttest control group design. This research was conducted in Grade VIII of Junior High School with 72 research samples. Data were analysed by using Multivariate Analysis of Variances (Manova). Result: Data analysis showed that ECPPB learning strategy was better to improve students’ knowledge ARH, students’ attitude toward reproduction health, and students’ skill in ARH problem solving than students who were treated by using conventional teaching strategy in which the p = 0.0001(p < 0,05). The Partial Ata Squared (PTA) was 87.4 %, which means the learning strategy was able to improve learning achievement as much as 87.4 %. The highest improvement of learning achievement by using ECPPBlearning strategy was on students’ skill in ARH problem solving (PES=80.9%). Improvement of health reproduction attitude was 63.2 %, and improvement of students’ knowledge about reproduction health was 25.1%. Conclusion: Based on the result of this study was suggested in order to students be given EARH was integrated on the subject of science in junior high school by using ECPPB strategy.