Background: Pica, hunger, or thirst are common causative factors for poisoning in childhood. Children are at more risk of accidental poisoning due to their impulsive alertness, curious mind, virtue, and habit of mouthing of objects. There are many measures for interruptions and safety to prevent poisoning in pediatric age group still morbidity and mortality among children are higher. Health policy makers and managers should have robust information regarding types of poisoning, place, substances, etc. to prepare effective protective strategies. This study will provide such information. Aim and Objectives: The aim of the study was to identify epidemiological determinants of poisoning in pediatric age group. Materials and Methods: It is an observational and cross-sectional study. Total study population (n = 204) of poisoning in the age group (1–13 years) conducted at M.P. Shah Medical College, Guru Govind Sinh hospital, Jamnagar. Data were collected from the Medical Records Department section of hospital, from January to December for 1 year of 2013. Results: Kerosene was the most frequent poisoning agent found in this study. Incidence establishes more in age group of 2–4 years. Boys were affected much as compared to girls. Home was found common place of oisoning, others were playground and school. All cases were accidental in nature. April and October months have more cases as compared to other months. Conclusion: Majority of the cases were accidental in nature among young children so precautions like conventional storage methods and disposal facilities of chemicals or guardian awareness can sufficiently decrease the occurrence.