Medical Industry Research Articles

Design of dual peak star shaped metamaterial absorber for S and C band sensing applications

This paper presents the detailed design configuration and investigation of a small-scale dual-band metamaterial absorber (MTMA) for solid and liquid sensing applications. The overall dimension of the MTMA unit cell is 10 × 10 × 1.57 mm3 and constitutes an affordable FR-4 substrate. The absorber exhibits dual absorption peaks at 3.470 GHz for the S-band and 7.219 GHz for the C-band, respectively. Both absorption characteristics have been validated through comprehensive simulation and experimental procedures. The dual-band absorption rate exceeded 99% during simulations, and experimental validation showed an absorption rate above 98%. For sensing applications, various solid materials, including different Rogers substrates ( RT 5880, RT 5870, RT 4003 and RT 4835) and liquids such as sunflower and crown oil, were utilized. Our findings indicate that the proposed MTMA achieves a maximum Q-factor of 191 and a sensitivity of up to 2.5 for both solid and liquid sensing applications compared to previous studies. The simulation and experimental validation of the result indicate that suggested MTMA can be effectively used in different sensing applications such as the medical and communications industry.

Optimization of a sustainable supply chain for medical device industry under uncertainty and COVID-19 pandemic

Optimization of a sustainable supply chain for medical device industry under uncertainty and COVID-19 pandemic

Stability and bifurcation analysis of a 2DOF dynamical system with piezoelectric device and feedback control

This study aims to demonstrate the behaviors of a two degree-of-freedom (DOF) dynamical system consisting of attached mass to a nonlinear damped harmonic spring pendulum with a piezoelectric device. Such a system is influenced by a parametric excitation force on the direction of the spring’s elongation and an operating moment at the supported point. A negative-velocity-feedback (NVF) controller is inserted into the main system to reduce the undesired vibrations that affect the system’s efficiency, especially at the resonance state. The equations of motion (EOM) are derived by using Lagrangian equations. Through the use of the multiple-scales-strategy (MSS), approximate solutions (AS) are investigated up to the third order. The accuracy of the AS is verified by comparing them to the obtained numerical solutions (NS) through the fourth-order Runge-Kutta Method (RK-4). The study delves into resonance cases and solvability conditions to provide the modulation equations (ME). Graphical representations showing the time histories of the obtained solutions and frequency responses are presented utilizing Wolfram Mathematica 13.2 in addition to MATLAB software. Additionally, discusses the bifurcation diagrams, Poincaré maps, and Lyapunov exponent spectrums to show the various behavior patterns of the system. To convert vibrating motion into electrical power, a piezoelectric sensor is connected to the dynamical model, which is just one of the energy harvesting (EH) technologies with extensive applications in the commercial, industrial, aerospace, automotive, and medical industries. Moreover, the time histories of the obtained solutions with and without control are analyzed graphically. Finally, resonance curves are used to discuss stability analysis and steady-state solutions.

Efficient directional biosynthesis of isoquercitrin from quercetin by Bacillus subtilis CD-2 and its anti-inflammatory activity

Isoquercetin, as the sole product, was directionally biosynthesized from quercetin in a non-aqueous system using Bacillus subtilis CD-2 (1 g/L quercetin), and its structure was identified by LC-MS and NMR analysis. CCK8 assays showed no cytotoxicity and good cell proliferation. The anti-inflammatory experiments demonstrated strong inhibition of NO release, transcriptional downregulation of classical effective cellular factors tumour necrosis factor-α, interleukin-6, interleukin-1β, and transcriptional upregulation of interleukin-10 in LPS-induced RAW264.7 cells. Its stronger anti-inflammatory activity than quercetin provided a reference for modifying the structure of quercetin to obtain more compounds with better pharmacological activities for medical industry.

Polymer Nanocomposites: A Review on Recent Advances in the Field of Green Polymer Nanocomposites

Abstract: In order to address environmental issues, polymer nanocomposites are becoming more and more popular because of their remarkable functionality. Their use in various fields is highlighted by their special physicochemical features (i.e., stability, high reactivity, robustness, regenerability, etc.), conductivity, electronic compatibility, quick interfacial contacts, simplicity of functionalization, simplicity of synthesis, interface-to-volume ratio, and low cost. Green polymer nanocomposites have drawn a lot of attention for use in a variety of applications to preserve the environment. Because they are made of eco-friendly materials, they are frequently utilised in the automobile, building, packaging, and medical industries. Eco-friendly solutions to the problems caused by plastic trash are biodegradable polymers produced from renewable sources (microbes, plants, and animals). Plant fibres and natural resins are combined to create green composite materials. These fibres and resins used in green composites can be broken down by bacteria. The mixing of natural fillers and organic polymers results in green polymer nanocomposites with distinct characteristics. This review is anticipated to be comprehensive, compelling, and practical for the scientists and business professionals who collaborate to address a variety of environmental problems on a global scale using green polymer nanocomposites.

Ultraviolet-diethyl sulfate composite mutagenesis of Rhodosporidium toruloides and culture optimization to improve carotenoid production

Rhodosporidium toruloides is a carotenoid-producing oleaginous yeast, and its carotenoids are of considerable value to food, chemical, and medical industries. In this study, to improve carotenoid production capacity, the parent R. toruloides strain (CK) was compound mutagenized using ultraviolet-diethyl sulfate (UV-DES), and cultivation conditions were simultaneously optimized to enhance the carotenoid synthesis ability of the mutant strain (M5). The carotenoid content was significantly increased following UV-DES compound mutagenesis (CK = 249.34 μg/g, M5 = 535.28 μg/g). The carotenoid content of M5 was increased to 763.85 μg/g under optimal culture conditions. In addition, mutagenesis altered the carotenoid components, and torulene and torularhodin levels were also increased following mutation, leading to changes in antioxidant capacity. Real-time quantitative PCR results showed that expression of six genes (CAR1, CAR2, CrtE, CrtI, ME1, HMG1) related to carotenoid accumulation were significantly upregulated by UV-DES composite mutagenesis. In conclusion, combined UV-DES mutagenesis and optimal culture conditions promoted the biosynthesis of carotenoids in R. toruloides.

PHYSICOCHEMICAL AND SPECTROSCOPIC ANALYSIS OF INTERACTIONS BETWEEN ASPIRIN AND NORMAL SALINE AT DIFFERENT TEMPERATURES

The primary goal of the current investigation is to explore the molecular interactions between the aspirin (2-Acetoxybenzoic acid) and normal saline (0.9% w/v aqueous NaCl) at various concentrations (0.001–0.010) m and temperature (T= 300.15–315.15) K. To understand the various possible molecular interactions, volumetric, acoustic, conductometric and viscometric parameters were evaluated using experimental measured values of densities (ρ), ultrasonic velocities (u), specific conductance (κ), and viscosities (η). The results derived from these parameters have been examined in terms of drug–solvent and drug-drug interactions. The results of physicochemical studies indicate that aspirin exhibits strong interactional and structure–forming behaviour in normal saline. These results were well supported by UV-visible spectral studies which indicate the existence of intense aspirin–normal saline interactions in the form of modification in absorption maximum and absorption wavelength. The cyclic voltammetric studies were also performed to explore the oxidation/reduction behaviour and effect of aspirin on hemolysis. The experimental analysis of these studies provides valuable insights for better drug design, drug delivery, compatibility, potential safety, and biological relevance for the pharmaceutical and health industries.

Assessing the shielding capability of NiO-infused BPSCCO ceramics against low-energy X-rays

This research examines the improvement of radiation shielding capabilities in Bismuth Strontium Calcium Copper Oxide (BSCCO) superconductors via NiO doping. With the increasing need for advanced shielding materials in high-risk areas, exploring effective and nonhazardous alternatives is becoming increasingly important. The purpose of the study was to investigate the radiation-shielding characteristics of BPSCCO superconducting ceramics and the effects of NiO additives on their shielding properties. Comparisons of linear attenuation coefficient (LAC), mass attenuation coefficient (MAC), half-value layer (HVL), tenth-value layer (TVL), mean free path (MFP), as well as fully simulated values for transmission factor (TF), neutron removal cross section (ΣR), electrical conductivity (Ceff), alpha and proton stopping powers, and radiation protection efficiency (RPE) using NIST XCOM, Phy-X, NIST Pstar and NIST Astar for all ceramic samples. The results indicate that optimal NiO doping notably enhances the radiation shielding capabilities of BSCCO ceramics, highlighting their significant potential for use in the medical, aerospace, and nuclear industries. This research provides a fundamental understanding of the potential of doped superconductor ceramics for radiation protection, promoting further research into these materials and the creation of safer, more efficient shielding solutions.

2025 ACSM Worldwide Fitness Trends: Future Directions of the Health and Fitness Industry

Apply It! • Identify predictions for the top 20 fitness trends in the United States and across the globe for 2025. • Utilize data informed decision making to promote physical activity in the commercial, clinical, corporate, and community fitness sectors. • Evaluate trend themes across regions to support consumer health and fitness.

Risk-oriented source apportionment and implications for mitigation strategies of VOCs in industrial parks: Insights from odor pollution and health risks

A typical industrial park in the upper reaches of the Yangtze River Economic Belt, which is 70 km from the Chongqing urban center, was used to investigate the occurrence and exposure of harmful volatile organic compounds (VOCs). An exposure risk method and a risk-oriented source apportionment approach were performed to assess the inhalation risks and apportion VOC sources, respectively. The quantitative relationships between risk factors and pollution sources were established, identifying key pathogenic and odorous VOCs. The quantitative emission reduction strategies were developed based on risk thresholds. Residents within the industrial parks face potential health risks due to pathogenic VOCs and nuisance odors, and workers in specific sectors experience two to six times higher risks than those in residential areas. Six risk sources were identified in the industrial park, ranked according to their contribution to VOC concentrations as follows: industrial sewage treatment (IST) (32.59 %), natural gas chemical industry (NGCI) (27.77 %), diesel vehicle exhaust (DVE) (12.04 %), pharmaceutical manufacturing industry (PMI) (11.14 %), chemical raw materials manufacturing (CRMM) (9.96 %), and iron and steel industry (ISI) (6.5 %). Among these, NGCI, IST, and CRMM were the top contributors to pathogenic risks, with contributions of 32.13 %, 29.71 %, and 21.71 % to non-carcinogenic risks, and 18.15 %, 19.87 %, and 27.99 % to carcinogenic risks, respectively. DVE produced significantly higher odor pollution compared to other sources, with intensities that were 3 to 10 times greater. The key pathogenic and odorous VOCs differ by source, resulting in varying control priorities for different VOC species. Reducing emissions from these six sources for 20 high-risk species (e.g., acrolein, 2-chlorotoluene, 1,2-dibromoethane, dichloromethane, and p-diethylbenzene) will simultaneously lower pathogenic and odor risks, with cumulative reduction rates ranging from 4.11 % to 93.75 %. This study provides quantitative control targets for VOCs from a health risk perspective, offering valuable guidance for developing risk management policies in industrial parks.

Occupational health and safety in the construction industry: a comprehensive review with emphasis on Nigeria

The construction industry holds remarkable benchmarks of aptitude and creativity; however, it is among the most lethal industries when it comes to occupational health and safety (OHS). This study incorporates a detailed analysis of the key OHS issues within the construction sector with a special regard for developing countries such as Nigeria. The paper discusses different physical, chemical, biological, and psychological risks within the industry and highlights the importance of compliance with OHS requirements aimed at avoiding mishaps, incidents, and even fatalities. Moreover, it discusses the issues relating to poor training, funding limitations, and project pressures while highlighting the significance of maintaining a strong safety culture, workers' awareness, and compliance in enhancing OHS results. In addition to that, the review also examines current safety measures, identifies gaps, and suggests improvements, drawing on global best practices to inform future policies and strategies. This study serves as a valuable resource for policymakers, construction stakeholders, and employers to minimize health risks and optimize construction workers’ productivity and well-being.

Graphene: future prospects for biomedical engineering applications

Graphene is one of the allotropic forms of Carbon. It is typically presented as a thin, almost transparent, and very lightweight sheet, despite its remarkable mechanical strength. Recent studies have demonstrated that graphene has significant potential for application in the medical industry, not only due to its mechanical resistance and lightness, which suggest its use in prosthetics and bionic limbs, but also because of its excellent electrical conductivity, indicating its potential in medical measurement equipment. Moreover, graphene's biocompatibility and resistance to corrosion make it an ideal material for long-term medical implants. It has been explored in the development of biosensors, enabling real-time monitoring of biological signals such as heart rate and brain activity. For instance, graphene-based sensors could be implanted to detect subtle electrical changes in neurons, which might be particularly useful in neuroprosthetics or for individuals with spinal cord injuries. Graphene's flexibility also paves the way for the creation of flexible electronic devices that could be worn on the skin or integrated into clothing for continuous health monitoring. These innovations could revolutionize personalized medicine by offering more accurate, accessible, and non-invasive diagnostic tools. As research continues to advance, graphene holds the promise of transforming biomedical engineering with cutting-edge applications that could improve patient care and treatment outcomes.

Abstracts from the 2024 Chinese Congress on Gerontology and Health Industry November 1st - 3rd 2024 Haikou, Hainan Province, the People's Republic of China.

Abstracts from the 2024 Chinese Congress on Gerontology and Health Industry November 1st - 3rd 2024 Haikou, Hainan Province, the People's Republic of China.

Abstracts from the 2024 Chinese Congress on Gerontology and Health Industry November 1st - 3rd 2024 Haikou, Hainan Province, the People's Republic of China.

Abstracts from the 2024 Chinese Congress on Gerontology and Health Industry November 1st - 3rd 2024 Haikou, Hainan Province, the People's Republic of China.

Investment Research of China Medical Device Industry under the Concept of Corporate Finance — Take Yuyue Medical Co., Ltd. as Example

With the optimization of China’s healthcare policy, the rise of the aging population, the increasing health awareness of society, and the impact of the global epidemic, China’s medical device industry has become a key market for investors. However, compared with the mature and well-funded medical device companies in overseas developed countries, China’s local medical device companies have apparent disadvantages and jumping battles. Yuyue Medical Co., Ltd. is a prominent player in the medical device industry in China, having sustained a significant profit margin over an extended period. Its profitability has changed over the post-epidemic period, in any case. Given Yuyue Medical Co., Ltd.’s exceptional standing in the medical equipment sector, an analysis of the company as an industry investment case makes sense. Based on Yuyue Medical Co., Ltd. as the industry investment benchmark, the study analyses the industry’s competitive development situation, financial performance, and impact on the external environment by adopting Porter’s Five Forces, ratio analysis, and PESTEL. The study found that China’s medical device industry has growth potential due to the low bargaining power of customers and suppliers, high technological barriers, and low threat of substitution by new entrants. Yuyue Medical Co., Ltd. has healthy financial performance and several advantages from the external environment, so Yuyue Medical Co., Ltd. is worthy of investment.

Trainee's Perceptions on Simulation-Based Education and Its Impact on Transitioning to the Role of Medical Registrar: A Qualitative Study.

Background and aim In 2019, a three-year internal medicine training (IMT) program replaced the two-year core medical training program in the United Kingdom, incorporating the first year of medical registrar (MR) training into the same curriculum. In light of the considerable evidence supporting the effectiveness of simulation-based education (SBE) and the challenges inherent in transitioning, the design and delivery of SBE are now ideally positioned to facilitate this transition process and assess its impact. However, trainees' perceptions regarding the effectiveness of SBE in the IMT curriculum for transitioning to the MR role are not well-documented. This study aimed to explore and examine trainees' views on SBE in the IMT curriculum to prepare them to transition to the role of the MR. It sought to identify the critical qualities and skills that IMT trainees believe SBE should address to enable them to successfully fulfill the MR role, as well as to assess the extent to which internal medicine year three trainees perceive that SBE in its current form within the IMT curriculum has prepared them for the role of MR. Methods This qualitative study employed focus groups to explore individuals' perspectives on SBE in the IMTcurriculum and its role in preparing them for the transition to the MR position. Four focus groups were conducted, two with core trainees (CTs) and two with MRs. Sessions were recorded, transcribed verbatim, and analyzed using a thematic analysis approach. Results Eleven trainees participated in the study. Seven of them were CTs, with the remaining four in their first year as a MR. Six main themes emerged from the data, grouped into two main headings. The heading titled "Perceptions of SBE" included the themes "Valuable Teaching Tool," "A Squandered Resource," and "Avoid Over-Reliance." In contrast, the heading "Areas/Suggestions for Improving SBE" included the themes "Quantity and Scheduling," "Feedback," and "Draw on Others' Experiences." Conclusion The value of SBE was recognized, alongside the vital role of high-quality feedback. Other medical specialties and industries were highlighted for their effective implementation of SBE, offering a possible standard for educators involved in the IMT curriculum to pursue. There was a perception that SBE did not adequately supportthe ongoing maintenance of skills, placing considerable reliance on real-world clinical practice to fulfill this need. The limitations inherent in SBE were acknowledged, and educators are encouraged to explore ways to optimize the use of all educational tools at their disposal, which may include the formal introduction of a shadowing period for trainees.

Innovations in Biodegradable Batteries: A Sustainable Future

The increasing demand for batteries in several industries such as medical and electric car (EV) Industry has led to significant environmental challenges due to the production and disposal of traditional batteries, which are nonbiodegradable and pose risks to ecosystems. This report investigates the potential of biodegradable batteries as a sustainable alternative to traditional batteries, aiming to minimize environmental impact. This study analyzing and comparing the fiber batteries, zinc-molybdenum batteries, plant-based batteries (Flower battery), crab shell battery as well as algal biopolymers battery. It also highlights the key materials, methods for manufacture, and performance characteristics (biodegradability, energy capacity, degradation time) of each type of biodegradable batteries. The findings suggest that biodegradable batteries offer promising solutions for specific applications, such as in biomedical devices, wearable electronics, and precision agriculture, where their biocompatibility and environmental safety are crucial. Future development should focus on enhancing energy density, optimizing degradation timelines, and reducing costs to make these batteries more competitive with traditional options.

Immobilization of Phospholipase D on Magnetic Graphene Oxide for Efficient Phosphatidylserine Production

Phosphatidylserine (PS) has significant applications in various sectors, such as the medical and food industries. However, its production relies heavily on phospholipase D (PLD), a crucial tool that is hindered by issues like poor stability and irrecoverability. Immobilization presents itself as an effective solution to overcome these limitations. In this study, magnetic graphene oxide (MGO) modified with an amino (NH2) group was synthesized and utilized for PLD immobilization. The activity of the immobilized PLD (MGO-PLD) reached 3062 U/gMGO, with a specific activity of 33.9 U/mgPLD, virtually identical to that of the free PLD. MGO-PLD was utilized to synthesize PS efficiently in a biphasic system. Under optimal conditions, the PS yield reached 18.66 g/L, with a conversion rate of 92.8% and a productivity of 3.11 g/L/h. Notably, MGO-PLD retained an impressive PS conversion rate of 77.4% even after seven repetitive usages. Moreover, MGO-PLD displayed enhanced thermal and pH resistance properties compared to free PLD, alongside augmented storage stability. After an 8-week preservation at 4 °C, its residual activity was maintained at 76.3%. This study provides a sustainable and highly efficient pathway for the biocatalytic synthesis of PS.

Application of polymer adhesive hydrogel in wound healing

As the global adhesive industry continues to grow, researchers are discovering that polymer adhesives are playing an increasing role in the medical field, polymer adhesives have attracted more and more attention from the medical industry due to their unique advantages, such as hydrogels, have gradually appeared, which can effectively help wound healing. Most of the hydrogels have good biocompatibility and water absorption, and have the advantages of controllable structure, adjustable performance and easy degradation. Compared with traditional wound healing methods, hydrogels effectively reduce additional trauma and leakage and allow for greater tissue integration. This paper reviews the types of polymeric adhesive hydrogels and examples of some of them being artificially modified to be applied to the field of wound healing. Analyzes their mechanism of action and the advantages and shortcomings of their clinical applications, and finally looks into the potential functions and clinical efficacy of hydrogels in the future.

Exploring In Vitro Antibiofilm Potential and In Vivo Toxicity Assessment of Gold Nanoparticles.

In this study, biogenically synthesized AuNPs were first characterized via UV visible spectroscopy, SEM, XRD, and FTIR followed by toxicity evaluation using mice model. UV-visible spectroscopy of biogenic AuNPs showed peaks at 540-549 nm, while FTIR spectrum showed various functional groups involving O-H, Amide I, Amide II, O-H, C-H groups, and so on. SEM showed the size variation from 30 to 60 nm. Antibacterial potential against pathogenic isolates showed bigger ZOI (31.0 mm) against Pseudomonas aeruginosa AuNPs. Antibiofilm activity showing up to 100% inhibition at 90 µg mL-1 concentration of AuNPs. Toxicity evaluation showed LD50 as 70 mg kg-1. Exposure to AuNPs caused significant changes in the levels of serum AST (p < 0.05) at 100-150 mg kg-1 of AuNPs exposure. Histopathology of male albino mice kidney and liver revealed that mice exposed to maximum concentration of AuNPs showed necrosis, cell distortion, and hepatocytes detachment. Present study showed that biologically synthesized AuNPs possess effective antimicrobial and biofilm inhibitory potential. AuNPs strong bactericidal effect even at lower concentration suggest that NPs could have excellent potential for combating pathogens. In conclusion, nanotechnology may revolutionize human life and medical industry by developing innovative drugs with the potential to treat diseases in shorter and noninvasive time period. Hence, in vitro biosafety and experimental observations followed by in vivo outcomes are crucial in shifting the novel therapeutics into medical practice thus leading further into their future development.