In this paper, environmental epidemiology data have been used in order to correlate air pollutants emitted from the Wazo Hill Cement Factory with the health of human communities Tegeta and Boko villages, which surround the factory. In this study, descriptive routing data and retrospective and cross-sectional studies of environmental epidemiological approaches are used. Data are collected from three dispensaries and two hospitals. The cross-sectional studies were then applied to compare the diseases in selected places with predicted ground level air pollution concentration and the measured exposure. Diseases such as PUO, chest pain, cough, RTI, and eye problems in the two-case study villages have shown that they may be environmentally derived due to cement dust. Moreover, the higher percentage of related diseases occurs near the source of pollutant. A relative risk ratio assessment indicates that in the two villages, the exposed subjects are 7.5 and 22.5 times in the two villages as likely to develop the disease during the follow-up period than the unexposed subjects.