PurposeRegardless of the diverse research on big data analytics (BDA) across different supply chains, little attention has been paid to exploit this information across service supply chains. The healthcare supply chains, where supply chain operations consume the second highest expenditures, have not completely attained the potential gains from data analytics. So, this paper explores the challenges of BDA at various levels of healthcare supply chains.Design/methodology/approachDrawing on the resource-based view (RBV), this research explores the various challenges of big data at organizational and operational level of different nodes in healthcare supply chains. To demonstrate the links among supply chain nodes, the authors have used a supplier-input-process-output-customer (SIPOC) chart to list healthcare suppliers, inputs (such as employees) supplied and used by the main healthcare processes, outputs (products and services) of these processes, and customers (patients and community).FindingsUsing thematic analysis, the authors were able to identify numerous challenges and commonalities among these challenges for the case of healthcare supply chains across United Arab Emirates (UAE). An applicable exploration on organizational (Socio-technical) and operational challenges to BDA can enable healthcare managers to acclimate efficient and effective strategies.Research limitations/implicationsThe identified common socio-technical and operational challenges could be verified, and their impacts on the sustainable performance of various supply chains should be explored using formal research methods.Practical implicationsThis research advances the body of literature on BDA in healthcare supply chains in that (1) it presents a structured approach for exploring the challenges from various stakeholders of healthcare chain; (2) it presents the most common challenges of big data across the chain and finally (3) it uses the context of UAE where government is focusing on medical tourism in the coming years.Originality/valueOriginality of this work stems from the fact that most of the previous academic research in this area has focused on technology perspectives, a clear understanding of the managerial and strategic implications and challenges of big data is still missing in the literature.