In order to avoid cardiac complications, patients with coronary artery disease (CAD) should the effect of self-care agency on health risk behaviors. Coronary artery engage in heart-healthy behaviors. Therefore, it is presumed that individuals have acquired self-care agency and a thorough understanding of their disease. Therefore, we investigated the associations between healthy affect, Self-Care, Disease Knowledge to improve their Health Risks status of patient. A descriptive-correlational design involving patients with having coronary artery disease (CAD) and being treated in Ho Chi Minh City. The participants (N =191) who living in Binh Chanh, Nha Be, Can Gio and answer questionnaires which included Exercise in Self-care Agency scale (ECSA), Health Behavior Scale (HBS) and the Baecke questionnaire. The Linear regression correlation coefficient analysis, and computed r was applied this study. Result showed significant predictive relationships between self-care agency, disease-related knowledge, and health risk behaviors. Higher levels of self-care agency and disease-related knowledge were associated with lower health risk behaviors. Gender, marital status, and specific health conditions like hypertension and stroke also played significant roles in influencing health risk behaviors. Mediation analysis further revealed that disease-related knowledge partially mediates disease, self-care, health knowledge, health behavior.
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