Skin blood-pressure was measured in 30 lower limbs, of which 10 were normal, 10 had ileofemoral stenosis, and 10 had popliteal arterial stenosis. A Heaf gun was used to inject the skin with a concentrated solution of histamine and a transparent sphygmomanometer cuff was placed around the leg over the localised flare. The pressure at which blanching of the skin disappeared, as the inflated transparent sphygmomanometer cuff was gradually deflated, was called skin occlusive blood-pressure. This test may be of considerable clinical value.