In view of the abnormal vibration of the body end wall during the high-speed operation of electric multiple units (referred hereafter as EMU), the vibration and noise characteristics of the body end wall area are analyzed through the line test. Combined with the end wall modal simulation results, the generation mechanism of the abnormal vibration of the body end wall is analyzed. The results show that when the train is running at a high speed, the aerodynamic excitation of the windshield cavity outside the body end wall acts on the end wall, arousing the first-order bending natural frequency of the body end wall, resulting in resonance of the body end wall, and then causing abnormal vibration and noise in the body end wall area. In order to solve this problem, installing a deflector (guiding plate) above the windshield in the vehicle body end wall area can effectively suppress the aerodynamic excitation acting on the vehicle body end wall. After optimization, the abnormal vibration and noise in the vehicle body end wall area are significantly reduced. The corresponding peak value at 40 Hz of the vehicle body end wall vibration spectrum is reduced by 85%, and the peak noise is reduced by 12%, The correctness of the mechanism analysis of abnormal vibration in the headwall area is verified, which provides a reference basis for guiding the structural optimization and operation and maintenance of rail vehicles.