Multidisciplinary care is a cornerstone of head and neck cancer (HNC) management, with prior studies highlighting improved functional and survival outcomes when utilizing an integrated approach. While the National Comprehensive Cancer Network (NCCN) guidelines recommend that “all patients need access to the full range of support services and specialists with expertise” in the management of HNC, the timing and frequency of these interventions has not been clearly defined. The Care Pathway Model (CPM) is a clinical roadmap that defines and standardizes the patient care experience throughout treatment and survivorship, permitting predictable and consistent prescription of multidisciplinary services. In line with the clinical vision of our Head and Neck Cancer Center of Excellence, we sought to develop CPMs to standardize our patient-centric, multidisciplinary approach to HNC care. Representatives across all disciplines participated in the CPM decision-making process. These included physician providers from Medical, Radiation and Surgical Oncology, supportive service providers (Nursing, Speech Language Pathology, Nutrition, Physical/Occupational Therapy, Social Work, Patient Navigation) and our program administrator. Multiple small group discussions were required to create the CPMs, with decisions surrounding timing and frequency of visits based on specialty clinical expertise, recommendations from the available literature, and feasibility based on our program’s infrastructure. Four CPMs were devised and implemented, including pathways for definitive chemoradiation, surgery followed by adjuvant radiation, surgery alone, and radiation alone. Order sets for each pathway were built into the electronic medical record to facilitate referral generation. A patient navigator program was developed to assist with care transitions. An education course was designed for new HNC patients to facilitate early introduction of the multidisciplinary paradigm. An education booklet will provide pertinent resources specific to HNC patients. Survivorship follow-up plans based on NCCN guidelines were created, with handouts provided to patients. Additionally, a nurse practitioner-driven survivorship clinic is underway. These pathways have provided the framework for implementation of integrated, highly coordinated multidisciplinary care. Our future directions include rigorous evaluation of how these CPMs impact functional and survival outcomes as well as overall patient experience.