An extreme drought occurred from 1876 to 1878 in most regions of northern China, leading to a series of social impacts, including harvest failures, price inflation, and population migration. Most regions of the Northern Hemisphere concurrently experienced extreme drought. Here, we use reconstructed high-resolution hydroclimatic (Palmer Drought Severity Index/precipitation) datasets and investigate the seasonal–annual hydroclimatic spatial patterns and drought intensity in North China from 1876 to 1878. Furthermore, we select combined sea surface temperature (SST) modes with positive Indian Ocean Dipole (IOD)/Pacific Decadal Oscillation (PDO) and El Niño conditions from the 1200-year control run simulations of HadCM3 to determine the possible causes of this severe drought. The extent and intensity of the selected SST modes are similar to those in the Pacific and Indian oceans during the 1876–1878 period from the National Oceanic and Atmospheric Administration (NOAA) Extended Reconstructed Sea Surface Temperature (ERSST) dataset. The results show that the large-scale drought of 1876–1878 is mainly driven by El Niño and a positive PDO, while the effect of IOD is not significant. El Niño may trigger the circumglobal teleconnection of the Northern Hemisphere. And, the meridional disturbance of the eastward Rossby wave train at mid-latitudes may change the intensity of the troughs and ridges and further block water vapor transport from ocean to land.