Background: Nanohybrid composite resin is a dental restorative material that is widely used in modern dental practice. However, the interaction of these materials with acidic foods and drinks, such as pempek vinegar, can affect their mechanical properties. Materials and Methods: This research is laboratory experimental research with pretest-posttest with only group design. In this study, nanohybrid composite resin was used in the form of a circle on a mold with a thickness of 2 mm and a diameter of 10 mm which was immersed in a solution of pempek vinegar. The number of samples used is 6 samples with 4 test groups. The 4 test groups were divided into immersion times of 1,3,5,7 days. Results: After immersion, the results of the hardness of the composite resin were taken. Using the normality and homogeneity tests, the hardness test results data were processed. It was found that the data were normally distributed and not homogeneous for each data group. After that an analysis was carried out using independent t-test (p <0.005) it was found that there was a significant effect of the hardness of the composite resin on immersion in Pempek vinegar solution which was soaked for 3 days, 5 days and 7 days. Conclusion: Pempek vinegar solution affects the surface hardness of the nanohybrid composite resin which is probably influenced by pH, liquid absorption ability, and soaking time.
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